ATE220203T1 - Nachweis einer substanz durch brechzahländerung - Google Patents
Nachweis einer substanz durch brechzahländerungInfo
- Publication number
- ATE220203T1 ATE220203T1 AT99908814T AT99908814T ATE220203T1 AT E220203 T1 ATE220203 T1 AT E220203T1 AT 99908814 T AT99908814 T AT 99908814T AT 99908814 T AT99908814 T AT 99908814T AT E220203 T1 ATE220203 T1 AT E220203T1
- Authority
- AT
- Austria
- Prior art keywords
- substance
- laser
- detection
- change
- laser cavity
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
- G01N21/774—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01D—MEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
- G01D5/00—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable
- G01D5/26—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light
- G01D5/268—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light using optical fibres
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
- G01N21/45—Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
- G01N21/7746—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the waveguide coupled to a cavity resonator
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Optical Transform (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK9198 | 1998-01-23 | ||
| PCT/EP1999/000401 WO1999037996A1 (en) | 1998-01-23 | 1999-01-22 | Detection of a substance by refractive index change |
| US09/624,891 US6493090B1 (en) | 1998-01-23 | 2000-07-24 | Detection of a substance by refractive index change |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE220203T1 true ATE220203T1 (de) | 2002-07-15 |
Family
ID=26063288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99908814T ATE220203T1 (de) | 1998-01-23 | 1999-01-22 | Nachweis einer substanz durch brechzahländerung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6493090B1 (de) |
| EP (1) | EP1066507B1 (de) |
| JP (1) | JP2002501190A (de) |
| AT (1) | ATE220203T1 (de) |
| AU (1) | AU2829499A (de) |
| DE (1) | DE69902023T2 (de) |
| DK (1) | DK1066507T3 (de) |
| WO (1) | WO1999037996A1 (de) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001040757A2 (en) * | 1999-10-14 | 2001-06-07 | University Of Utah Research Foundation | Resonant optical cavities for high-sensitivity, high-throughput biological sensors and methods |
| US6592733B1 (en) * | 1999-11-12 | 2003-07-15 | Motorola, Inc. | Capillary electrophoresis devices incorporating optical waveguides |
| GB9927249D0 (en) * | 1999-11-18 | 2000-01-12 | Farfield Sensors Ltd | Device |
| WO2001098756A2 (en) * | 2000-06-20 | 2001-12-27 | The Regents Of The University Of California | Tunable laser cavity sensor chip |
| US6899849B2 (en) | 2000-07-28 | 2005-05-31 | The Regents Of The University Of California | Integrated sensor |
| WO2002021110A1 (de) * | 2000-09-04 | 2002-03-14 | Zeptosens Ag | System und verfahren zur multianalytbestimmung |
| WO2002027303A2 (en) * | 2000-09-25 | 2002-04-04 | Massachusetts Institute Of Technology | Optical micro-cavity sensors |
| US7384797B1 (en) | 2000-10-12 | 2008-06-10 | University Of Utah Research Foundation | Resonant optical cavities for high-sensitivity high-throughput biological sensors and methods |
| US7267797B1 (en) * | 2000-11-14 | 2007-09-11 | Cornell Research Foundation, Inc. | Nanofabricated photon tunneling based sensor |
| GR1004178B (el) * | 2001-11-29 | 2003-03-05 | "����������" | Ολοκληρωμενος οπτοηλεκτρονικος βιοαισθητηρας πυριτιου για ανιχνευση βιομοριων επισημασμενων με χρωμοφορες ομαδες ή νανοσωματιδια |
| US6810066B2 (en) * | 2002-02-20 | 2004-10-26 | Agilent Technologies, Inc. | Fiber-coupled tunable single-mode long-wavelength vertical-cavity laser |
| JP2004016609A (ja) * | 2002-06-19 | 2004-01-22 | Omron Healthcare Co Ltd | 体液成分濃度測定方法及び体液成分濃度測定装置 |
| US20050168749A1 (en) * | 2002-07-08 | 2005-08-04 | Hongke Ye | Optical olfactory sensor with holographic readout |
| US7619739B1 (en) * | 2002-08-29 | 2009-11-17 | Science Applications International Corporation | Detection and identification of biological agents using Bragg filters |
| WO2004034527A2 (en) | 2002-10-11 | 2004-04-22 | Canon Kabushiki Kaisha | Sensor |
| US7149396B2 (en) * | 2003-06-16 | 2006-12-12 | The Regents Of The University Of California | Apparatus for optical measurements on low-index non-solid materials based on arrow waveguides |
| US7447391B2 (en) * | 2004-05-11 | 2008-11-04 | Tel Aviv University Future Technology Ltd. | Planar-resonator based optical chemo- and biosensor |
| GB0415881D0 (en) * | 2004-07-15 | 2004-08-18 | Univ Southampton | Multiwavelength optical sensors |
| US7492979B2 (en) * | 2004-09-27 | 2009-02-17 | Hewlett-Packard Development Company, L.P. | Photonic crystal laser sensors and methods |
| US7289221B2 (en) * | 2004-09-27 | 2007-10-30 | Hewlett-Packard Development Company, L.P. | Mach Zehnder photonic crystal sensors and methods |
| WO2006047408A2 (en) * | 2004-10-22 | 2006-05-04 | Vanderbilt University | On-chip polarimetry for high-throughput screening of nanoliter and smaller sample volumes |
| US8178046B2 (en) * | 2005-02-23 | 2012-05-15 | Sierra Sensors Gmbh | Microfluidic devices with SPR sensing capabilities |
| DE102005027023A1 (de) * | 2005-06-11 | 2006-12-14 | Gerhart Schroff | Verfahren und Anordnung zur integralen Dichtheitsprüfung |
| KR20080031750A (ko) * | 2005-06-24 | 2008-04-10 | 코닌클리즈케 필립스 일렉트로닉스 엔.브이. | 랩온어칩 진단을 위한 집적 도파로 레이저 |
| US7218802B1 (en) | 2005-11-30 | 2007-05-15 | Corning Incorporated | Low drift planar waveguide grating sensor and method for manufacturing same |
| RU2422204C2 (ru) * | 2006-03-20 | 2011-06-27 | Конинклейке Филипс Электроникс Н.В. | Платформа система в корпусе для электронно-микрофлюидных устройств |
| US7428055B2 (en) * | 2006-10-05 | 2008-09-23 | General Electric Company | Interferometer-based real time early fouling detection system and method |
| US7652767B2 (en) * | 2006-10-19 | 2010-01-26 | Sporian Microsystems, Inc. | Optical sensor with chemically reactive surface |
| US7602496B2 (en) * | 2006-10-19 | 2009-10-13 | Sporian Microsystems, Inc. | Optical sensor with biologically reactive surface |
| US7746466B2 (en) * | 2007-05-14 | 2010-06-29 | The Regents Of The University Of California | System and method for flow cytometry |
| US7835013B2 (en) * | 2007-05-18 | 2010-11-16 | Vanderbilt University | Interferometric detection system and method |
| US8445217B2 (en) | 2007-09-20 | 2013-05-21 | Vanderbilt University | Free solution measurement of molecular interactions by backscattering interferometry |
| WO2009103339A1 (en) * | 2008-02-21 | 2009-08-27 | Valtion Teknillinen Tutkimuskeskus | Biosensor and a related manufacturing method |
| US7489835B1 (en) * | 2008-03-28 | 2009-02-10 | General Electric Company | Sensing system with fiber gas sensor |
| US9518288B2 (en) | 2008-04-11 | 2016-12-13 | University Of Utah Research Foundation | Methods and compositions related to quantitative, array based methylation analysis |
| WO2010008789A2 (en) * | 2008-06-23 | 2010-01-21 | University Of South Florida | Interferometric chemical sensor array |
| US8218151B2 (en) | 2009-03-12 | 2012-07-10 | Tel Aviv University Future Technology Development Ltd | Light-emitting intra-cavity interferometric sensors |
| DE102009013878B3 (de) * | 2009-03-16 | 2010-05-20 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Sensoranordnung und Detektionsverfahren |
| JP5373478B2 (ja) * | 2009-05-27 | 2013-12-18 | 日本航空電子工業株式会社 | 化学物質センサ |
| CN101694463B (zh) * | 2009-10-19 | 2011-07-20 | 浙江大学 | 半导体激光内腔光微流生物传感器 |
| US9772284B2 (en) | 2010-04-20 | 2017-09-26 | President And Fellows Of Harvard College | Biomedical and chemical sensing with nanobeam photonic crystal cavities using optical bistability |
| WO2011156713A1 (en) | 2010-06-11 | 2011-12-15 | Vanderbilt University | Multiplexed interferometric detection system and method |
| US8798414B2 (en) | 2010-09-29 | 2014-08-05 | President And Fellows Of Harvard College | High quality factor photonic crystal nanobeam cavity and method of designing and making same |
| US9562853B2 (en) | 2011-02-22 | 2017-02-07 | Vanderbilt University | Nonaqueous backscattering interferometric methods |
| US9273949B2 (en) | 2012-05-11 | 2016-03-01 | Vanderbilt University | Backscattering interferometric methods |
| CN103018200B (zh) * | 2012-11-30 | 2015-02-18 | 清华大学 | 透明介质折射率的监测装置及监测方法 |
| US9553419B2 (en) | 2014-08-22 | 2017-01-24 | Bae Systems Information And Electronic Systems Integration Inc. | Shared multi-wavelength laser resonator with gain selected output coupling |
| US10073188B2 (en) * | 2014-10-02 | 2018-09-11 | Halliburton Energy Services, Inc. | Three-dimensional waveguide sensors for sample analysis |
| WO2016118812A1 (en) | 2015-01-23 | 2016-07-28 | Vanderbilt University | A robust interferometer and methods of using same |
| US10627396B2 (en) | 2016-01-29 | 2020-04-21 | Vanderbilt University | Free-solution response function interferometry |
| CN107064012B (zh) | 2017-04-11 | 2019-06-25 | 山西大学 | 基于拍频效应的石英增强光声光谱气体检测装置及方法 |
| US11125689B2 (en) * | 2018-07-13 | 2021-09-21 | The Government Of The United States Of America, As Represented By The Secretary Of The Navy | Highly stable semiconductor lasers and sensors for III-V and silicon photonic integrated circuits |
| US11619580B2 (en) * | 2018-07-23 | 2023-04-04 | The University Of Chicago | Resonator-based ion-selective sensor |
| CN110514233B (zh) * | 2019-10-10 | 2024-04-26 | 中国计量大学 | 一种空腔悬浮通道型光纤线上马赫-曾德干涉仪 |
| US20220091031A1 (en) * | 2020-09-18 | 2022-03-24 | Salvus, Llc | Interferometric Detection and Quantification System and Methods of Use in Chemical Processing |
| CN113092385B (zh) * | 2021-05-10 | 2022-03-22 | 山东大学 | 中高层大气折射率测量装置及测量方法 |
| DE102021131644A1 (de) | 2021-12-01 | 2023-06-01 | Carl Zeiss Ag | Diffraktiver PIC Sensor |
| EP4644870A1 (de) * | 2024-05-03 | 2025-11-05 | Munster Technological University | Brechungsindexsensor |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4325635A (en) * | 1980-10-07 | 1982-04-20 | The United States Of America As Represented By The Secretary Of The Army | Heterodyne indicial refractometer |
| IT1155284B (it) * | 1982-02-10 | 1987-01-28 | Cselt Centro Studi Lab Telecom | Procedimento e apparecchiatura per la misura dell'indice di rifrazione e dello spessore di materiali trasparenti |
| US5465151A (en) * | 1993-01-21 | 1995-11-07 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon | Sensors employing interference of electromagnetic waves passing through waveguides having functionalized surfaces |
| US5513913A (en) * | 1993-01-29 | 1996-05-07 | United Technologies Corporation | Active multipoint fiber laser sensor |
| KR960015900B1 (ko) * | 1993-04-22 | 1996-11-23 | 국방과학연구소 | 광섬유 레이저를 이용한 물리량 측정장치 |
| US5437840A (en) | 1994-04-15 | 1995-08-01 | Hewlett-Packard Company | Apparatus for intracavity sensing of macroscopic properties of chemicals |
| US5793485A (en) | 1995-03-20 | 1998-08-11 | Sandia Corporation | Resonant-cavity apparatus for cytometry or particle analysis |
| US5766956A (en) | 1997-05-27 | 1998-06-16 | American Research Corporation | Diode laser-based chemical and biological sensor |
-
1999
- 1999-01-22 EP EP99908814A patent/EP1066507B1/de not_active Expired - Lifetime
- 1999-01-22 JP JP2000528855A patent/JP2002501190A/ja active Pending
- 1999-01-22 WO PCT/EP1999/000401 patent/WO1999037996A1/en not_active Ceased
- 1999-01-22 AT AT99908814T patent/ATE220203T1/de not_active IP Right Cessation
- 1999-01-22 AU AU28294/99A patent/AU2829499A/en not_active Abandoned
- 1999-01-22 DK DK99908814T patent/DK1066507T3/da active
- 1999-01-22 DE DE69902023T patent/DE69902023T2/de not_active Expired - Fee Related
-
2000
- 2000-07-24 US US09/624,891 patent/US6493090B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6493090B1 (en) | 2002-12-10 |
| WO1999037996A1 (en) | 1999-07-29 |
| DE69902023T2 (de) | 2003-02-27 |
| DE69902023D1 (de) | 2002-08-08 |
| EP1066507A1 (de) | 2001-01-10 |
| JP2002501190A (ja) | 2002-01-15 |
| AU2829499A (en) | 1999-08-09 |
| EP1066507B1 (de) | 2002-07-03 |
| DK1066507T3 (da) | 2002-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |