ATE220330T1 - Deltorphin zur behandlung von ischemie - Google Patents

Deltorphin zur behandlung von ischemie

Info

Publication number: ATE220330T1
Authority: AT; Austria
Prior art keywords: deltorphin; ischemia; seq; deltorphins; administered
Prior art date: 1998-05-01

Application number

AT99920203T

Other languages

English (en)

Inventor

Peter R Oeltgen

Mark S Kindy

Paul D Bishop

Original Assignee

Univ Kentucky Res Found

Zymogenetics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-05-01

Filing date

1999-04-30

Publication date

2002-07-15

1999-04-30 Application filed by Univ Kentucky Res Found, Zymogenetics Inc filed Critical Univ Kentucky Res Found

2002-07-15 Application granted granted Critical

2002-07-15 Publication of ATE220330T1 publication Critical patent/ATE220330T1/de

Links

208000028867 ischemia Diseases 0.000 title abstract 3
101800005209 Deltorphin Proteins 0.000 title abstract 2
BHSURCCZOBVHJJ-NWOHMYAQSA-N Deltorphin A Chemical compound C([C@H](N)C(=O)N[C@H](CCSC)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(N)=O)C1=CC=C(O)C=C1 BHSURCCZOBVHJJ-NWOHMYAQSA-N 0.000 title abstract 2
241000124008 Mammalia Species 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
108700040992 Ala(2)- deltorphin I Proteins 0.000 abstract 1
108700040991 Ala(2)- deltorphin II Proteins 0.000 abstract 1
201000006474 Brain Ischemia Diseases 0.000 abstract 1
206010008120 Cerebral ischaemia Diseases 0.000 abstract 1
NUNBRHVOPFWRRG-RCEFDBTISA-N Deltorphin B Chemical compound C([C@@H](C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@H](C(=O)N[C@@H](C(C)C)C(=O)NCC(N)=O)C(C)C)NC(=O)[C@@H](C)NC(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=CC=C1 NUNBRHVOPFWRRG-RCEFDBTISA-N 0.000 abstract 1
CJAORFIPPWIGPG-QXYJMILXSA-N Deltorphin C Chemical compound C([C@@H](C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C(=O)N[C@@H](C(C)C)C(=O)NCC(N)=O)C(C)C)NC(=O)[C@@H](C)NC(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=CC=C1 CJAORFIPPWIGPG-QXYJMILXSA-N 0.000 abstract 1
208000036982 Spinal cord ischaemia Diseases 0.000 abstract 1
230000037396 body weight Effects 0.000 abstract 1
230000002490 cerebral effect Effects 0.000 abstract 1
206010008118 cerebral infarction Diseases 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
230000000302 ischemic effect Effects 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
208000031225 myocardial ischemia Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cardiology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Heart & Thoracic Surgery (AREA)
Genetics & Genomics (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Plant Substances (AREA)
Medicinal Preparation (AREA)

AT99920203T 1998-05-01 1999-04-30 Deltorphin zur behandlung von ischemie ATE220330T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7123698A	1998-05-01	1998-05-01
PCT/US1999/009452 WO1999056766A2 (en)	1998-05-01	1999-04-30	Method for treating ischemia

Publications (1)

Publication Number	Publication Date
ATE220330T1 true ATE220330T1 (de)	2002-07-15

Family

ID=22100105

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99920203T ATE220330T1 (de)	1998-05-01	1999-04-30	Deltorphin zur behandlung von ischemie

Country Status (11)

Country	Link
EP (1)	EP1073451B1 (de)
JP (1)	JP2003522727A (de)
AT (1)	ATE220330T1 (de)
AU (1)	AU756200B2 (de)
BR (1)	BR9909876A (de)
CA (1)	CA2325387A1 (de)
DE (1)	DE69902096T2 (de)
MX (1)	MXPA00010616A (de)
NZ (1)	NZ507523A (de)
WO (1)	WO1999056766A2 (de)
ZA (1)	ZA200005920B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6900178B2 (en)	2000-09-12	2005-05-31	University Of Kentucky Research Foundation	Protection against ischemia and reperfusion injury
US6875742B2 (en)	2000-10-10	2005-04-05	Zymogenetics, Inc.	Method for treating cytokine mediated hepatic injury
US6645938B2 (en) *	2000-10-10	2003-11-11	Zymogenetics, Inc.	Protection against ischemia and reperfusion injury
KR20040096554A (ko)	2002-02-06	2004-11-16	비코르 테크놀로지스 인코포레이티드	경색방지 분자
EP2286731B1 (de)	2003-10-17	2012-05-09	Tyco Healthcare Group LP	Chirurgische Klammervorrichtung
US7705119B1 (en)	2007-04-09	2010-04-27	University Of Kentucky Research Foundation	Compositions and methods useful for treating circulatory and hypovolemic shock

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5656420A (en) *	1995-02-24	1997-08-12	University Of Kentucky Research Foundation	Method for employing the delta opioid dadle to extend tissue survival time during ischemia

1999
- 1999-04-30 JP JP2000546790A patent/JP2003522727A/ja active Pending
- 1999-04-30 EP EP99920203A patent/EP1073451B1/de not_active Expired - Lifetime
- 1999-04-30 CA CA002325387A patent/CA2325387A1/en not_active Abandoned
- 1999-04-30 NZ NZ507523A patent/NZ507523A/xx unknown
- 1999-04-30 DE DE69902096T patent/DE69902096T2/de not_active Expired - Fee Related
- 1999-04-30 AT AT99920203T patent/ATE220330T1/de not_active IP Right Cessation
- 1999-04-30 MX MXPA00010616A patent/MXPA00010616A/es unknown
- 1999-04-30 BR BR9909876-8A patent/BR9909876A/pt not_active Application Discontinuation
- 1999-04-30 WO PCT/US1999/009452 patent/WO1999056766A2/en not_active Ceased
- 1999-04-30 AU AU37758/99A patent/AU756200B2/en not_active Ceased
2000
- 2000-10-23 ZA ZA200005920A patent/ZA200005920B/en unknown

Also Published As

Publication number	Publication date
JP2003522727A (ja)	2003-07-29
CA2325387A1 (en)	1999-11-11
EP1073451A3 (de)	2003-06-04
WO1999056766A3 (en)	2003-04-17
ZA200005920B (en)	2003-03-05
AU756200B2 (en)	2003-01-09
DE69902096D1 (de)	2002-08-14
NZ507523A (en)	2002-09-27
WO1999056766A2 (en)	1999-11-11
BR9909876A (pt)	2000-12-19
MXPA00010616A (es)	2002-07-02
EP1073451A2 (de)	2001-02-07
EP1073451B1 (de)	2002-07-10
DE69902096T2 (de)	2003-02-27
AU3775899A (en)	1999-11-23

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Legal Events

Date	Code	Title	Description
2003-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties