BR0214967A - Composto, sal famaceuticamente aceitável, processo para a preparação de um composto, composição farmacêutica, uso de um composto e método de tratar um distúrbio de um paciente - Google Patents

Composto, sal famaceuticamente aceitável, processo para a preparação de um composto, composição farmacêutica, uso de um composto e método de tratar um distúrbio de um paciente

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Publication number
BR0214967A
BR0214967A BR0214967-2A BR0214967A BR0214967A BR 0214967 A BR0214967 A BR 0214967A BR 0214967 A BR0214967 A BR 0214967A BR 0214967 A BR0214967 A BR 0214967A
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BR
Brazil
Prior art keywords
compound
treating
pharmaceutically acceptable
acceptable salt
pharmaceutical composition
Prior art date
Application number
BR0214967-2A
Other languages
English (en)
Inventor
S Ren Ebdrup
Johannes Cornelis De Jong
Poul Jacobsen
Holger Claus Hansen
Per Veds
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of BR0214967A publication Critical patent/BR0214967A/pt

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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
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    • C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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Abstract

"COMPOSTO, SAL FARMACEUTICAMENTE ACEITáVEL, PROCESSO PARA A PREPARAçãO DE UM COMPOSTO, COMPOSIçãO FARMACêUTICA, USO DE UM COMPOSTO E MéTODO DE TRATAR UM DISTúRBIO DE UM PACIENTE". Uso de compostos para inibir lipase sensível-a-hormónio, composições farmacêuticas compreendendo os compostos, métodos de tratamento que empregam estes compostos e composições, e composos inéditos. Os presentes compostos são inibidores de lipase sensível-a-hormónio e podem ser úteis no tratamento e/ou prevenção de distúrbios médicos em que é desejável uma menor atividade de lipase sensível-a-hormónio.
BR0214967-2A 2001-12-14 2002-12-13 Composto, sal famaceuticamente aceitável, processo para a preparação de um composto, composição farmacêutica, uso de um composto e método de tratar um distúrbio de um paciente BR0214967A (pt)

Applications Claiming Priority (5)

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DKPA200101879 2001-12-14
DKPA200200645 2002-04-30
DKPA200201000 2002-06-27
DKPA200201562 2002-10-11
PCT/DK2002/000852 WO2003051841A2 (en) 2001-12-14 2002-12-13 Compounds and uses thereof for decreasing activity of hormone-sensitive lipase

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BR0214967A true BR0214967A (pt) 2005-05-10

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EP (2) EP1458374A2 (pt)
JP (2) JP2005518376A (pt)
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CN (1) CN1326519C (pt)
AU (2) AU2002351731A1 (pt)
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