ATE220665T1 - Azetidincarboxamidderivate zur behandlung von zns-erkrankungen - Google Patents
Azetidincarboxamidderivate zur behandlung von zns-erkrankungenInfo
- Publication number
- ATE220665T1 ATE220665T1 AT99901781T AT99901781T ATE220665T1 AT E220665 T1 ATE220665 T1 AT E220665T1 AT 99901781 T AT99901781 T AT 99901781T AT 99901781 T AT99901781 T AT 99901781T AT E220665 T1 ATE220665 T1 AT E220665T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- carboxamide derivatives
- cns diseases
- azetidine carboxamide
- azetidine
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title abstract 2
- PVXOUGHWLCBJOW-UHFFFAOYSA-N azetidine-1-carboxamide Chemical class NC(=O)N1CCC1 PVXOUGHWLCBJOW-UHFFFAOYSA-N 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9801499.6A GB9801499D0 (en) | 1998-01-23 | 1998-01-23 | Chemical compounds iii |
| GBGB9824458.5A GB9824458D0 (en) | 1998-11-06 | 1998-11-06 | Chemical compounds II |
| PCT/GB1999/000223 WO1999037613A1 (en) | 1998-01-23 | 1999-01-22 | Azetidinecarboxamide derivatives for treating cns disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE220665T1 true ATE220665T1 (de) | 2002-08-15 |
Family
ID=26313009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99901781T ATE220665T1 (de) | 1998-01-23 | 1999-01-22 | Azetidincarboxamidderivate zur behandlung von zns-erkrankungen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6831078B1 (de) |
| EP (1) | EP1049670B1 (de) |
| JP (1) | JP4542264B2 (de) |
| AT (1) | ATE220665T1 (de) |
| AU (1) | AU2178099A (de) |
| DE (1) | DE69902142T2 (de) |
| DK (1) | DK1049670T3 (de) |
| ES (1) | ES2181387T3 (de) |
| PT (1) | PT1049670E (de) |
| WO (1) | WO1999037613A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9917384D0 (en) * | 1999-07-23 | 1999-09-22 | Cerebrus Ltd | Chemical compounds-III |
| JP5621087B2 (ja) * | 2008-11-24 | 2014-11-05 | インテグレイティブ・リサーチ・ラボラトリーズ・スウェーデン・アーベー | 皮質のカテコールアミン作動性神経伝達のモジュレーターとして有用な新規な3−フェニル−アゼチジン誘導体 |
| CN115650893B (zh) * | 2022-10-24 | 2024-08-06 | 南通华祥医药科技有限公司 | 一种1-二苯甲基氮杂环丁烷-3-酮的合成方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB872447A (en) * | 1958-12-23 | 1961-07-12 | Lepetit Spa | 1-carbamyl-3-substituted azetidines |
| US4226861A (en) | 1978-04-18 | 1980-10-07 | A. H. Robins Company, Inc. | N-Lower-alkyl 3-phenoxy-1-azetidinecarboxamides |
| IL68699A (en) | 1982-08-19 | 1986-08-31 | Robins Co Inc A H | 3-phenoxy-1-azetidine-carboxamides,their preparation and pharmaceutical compositions containing them |
| US4505907A (en) | 1982-09-02 | 1985-03-19 | A. H. Robins Company, Inc. | N-Formyl and N-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides |
| IE58943B1 (en) * | 1985-02-28 | 1993-12-01 | Robins Co Inc A H | 3-Aryloxy-azetidine-carboxamides |
| US4956359A (en) * | 1985-02-28 | 1990-09-11 | A. H. Robins Company, Inc. | 3-aryloxy and 3-arylthioazetidinecarboxamides as anticonvulsants and antiepileptics |
-
1999
- 1999-01-22 JP JP2000528537A patent/JP4542264B2/ja not_active Expired - Lifetime
- 1999-01-22 PT PT99901781T patent/PT1049670E/pt unknown
- 1999-01-22 DK DK99901781T patent/DK1049670T3/da active
- 1999-01-22 ES ES99901781T patent/ES2181387T3/es not_active Expired - Lifetime
- 1999-01-22 AU AU21780/99A patent/AU2178099A/en not_active Abandoned
- 1999-01-22 US US09/600,631 patent/US6831078B1/en not_active Expired - Lifetime
- 1999-01-22 WO PCT/GB1999/000223 patent/WO1999037613A1/en not_active Ceased
- 1999-01-22 DE DE69902142T patent/DE69902142T2/de not_active Expired - Lifetime
- 1999-01-22 AT AT99901781T patent/ATE220665T1/de not_active IP Right Cessation
- 1999-01-22 EP EP99901781A patent/EP1049670B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT1049670E (pt) | 2002-12-31 |
| US6831078B1 (en) | 2004-12-14 |
| ES2181387T3 (es) | 2003-02-16 |
| AU2178099A (en) | 1999-08-09 |
| DE69902142D1 (de) | 2002-08-22 |
| JP4542264B2 (ja) | 2010-09-08 |
| DE69902142T2 (de) | 2003-01-09 |
| WO1999037613A1 (en) | 1999-07-29 |
| EP1049670B1 (de) | 2002-07-17 |
| JP2002501046A (ja) | 2002-01-15 |
| EP1049670A1 (de) | 2000-11-08 |
| DK1049670T3 (da) | 2002-11-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |