ES2193047T3 - (3,4 dihydro-2h-benzo(1,4) oxazinilmetil)(3-(1h-indol-3-il)-alquil)-aminas. - Google Patents
(3,4 dihydro-2h-benzo(1,4) oxazinilmetil)(3-(1h-indol-3-il)-alquil)-aminas.Info
- Publication number
- ES2193047T3 ES2193047T3 ES00902331T ES00902331T ES2193047T3 ES 2193047 T3 ES2193047 T3 ES 2193047T3 ES 00902331 T ES00902331 T ES 00902331T ES 00902331 T ES00902331 T ES 00902331T ES 2193047 T3 ES2193047 T3 ES 2193047T3
- Authority
- ES
- Spain
- Prior art keywords
- oxazinylmetil
- aminas
- alquil
- indol
- benzo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Indole Compounds (AREA)
Abstract
Compuesto de fórmula: **(Fórmula)** en la que: R es hidrógeno, alquilo de 1 a 6 átomos de carbono, fenilo, bencilo o fenilo sustituido; X e Y son, cada uno independientemente, hidrógeno, halógeno, ciano o alcoxi de 1 a 6 átomos de carbono; y m es 1 a 5; o una sal del mismo aceptable desde el punto de vista farmacéutico.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22683199A | 1999-01-07 | 1999-01-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2193047T3 true ES2193047T3 (es) | 2003-11-01 |
Family
ID=22850596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES00902331T Expired - Lifetime ES2193047T3 (es) | 1999-01-07 | 2000-01-06 | (3,4 dihydro-2h-benzo(1,4) oxazinilmetil)(3-(1h-indol-3-il)-alquil)-aminas. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1140925B1 (es) |
| JP (1) | JP2002534427A (es) |
| CN (1) | CN1335845A (es) |
| AT (1) | ATE238300T1 (es) |
| AU (1) | AU2406700A (es) |
| CA (1) | CA2355308A1 (es) |
| DE (1) | DE60002292T2 (es) |
| DK (1) | DK1140925T3 (es) |
| ES (1) | ES2193047T3 (es) |
| PT (1) | PT1140925E (es) |
| TW (1) | TW546299B (es) |
| WO (1) | WO2000040580A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0301458A2 (hu) | 2000-10-26 | 2003-10-28 | Smithkline Beecham Plc. | Benzoxazinonszármazékok, eljárás előállításukra és a vegyületek felhasználása |
| EP1373203A1 (en) | 2001-03-29 | 2004-01-02 | Bristol-Myers Squibb Company | Cyclopropylindole derivatives as selective serotonin reuptake inhibitors |
| WO2004106298A1 (en) * | 2003-05-30 | 2004-12-09 | Janssen Pharmaceutica N.V. | Indole derivatives with an improved antipsychotic activity |
| WO2006006741A1 (ja) | 2004-07-15 | 2006-01-19 | Japan Tobacco Inc. | 縮合ベンズアミド化合物及びバニロイド受容体１型(ｖｒ１)活性阻害剤 |
| US7635696B2 (en) | 2004-11-26 | 2009-12-22 | Janssen Pharmaceutica N.V. | Isoxazoline-indole derivatives with an improved antipsychotic and anxiolytic activity |
| US7906508B2 (en) | 2005-12-28 | 2011-03-15 | Japan Tobacco Inc. | 3,4-dihydrobenzoxazine compounds and inhibitors of vanilloid receptor subtype 1 (VRI) activity |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8803419D0 (en) * | 1988-02-15 | 1988-03-16 | Erba Carlo Spa | 1 4-benzoxazine & 1 4-benzothiazine derivatives & process for their preparation |
| JP2002510682A (ja) * | 1998-04-08 | 2002-04-09 | アメリカン・ホーム・プロダクツ・コーポレイション | うつ病治療用のインドール−３−イル−シクロヘキシルアミン誘導体（５−ｈｔ１受容体拮抗薬） |
-
2000
- 2000-01-05 TW TW089100094A patent/TW546299B/zh active
- 2000-01-06 PT PT00902331T patent/PT1140925E/pt unknown
- 2000-01-06 EP EP00902331A patent/EP1140925B1/en not_active Expired - Lifetime
- 2000-01-06 ES ES00902331T patent/ES2193047T3/es not_active Expired - Lifetime
- 2000-01-06 DK DK00902331T patent/DK1140925T3/da active
- 2000-01-06 CN CN00802505A patent/CN1335845A/zh active Pending
- 2000-01-06 JP JP2000592288A patent/JP2002534427A/ja active Pending
- 2000-01-06 WO PCT/US2000/000230 patent/WO2000040580A1/en not_active Ceased
- 2000-01-06 CA CA002355308A patent/CA2355308A1/en not_active Abandoned
- 2000-01-06 AT AT00902331T patent/ATE238300T1/de not_active IP Right Cessation
- 2000-01-06 AU AU24067/00A patent/AU2406700A/en not_active Abandoned
- 2000-01-06 DE DE60002292T patent/DE60002292T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK1140925T3 (da) | 2003-08-11 |
| WO2000040580A1 (en) | 2000-07-13 |
| ATE238300T1 (de) | 2003-05-15 |
| DE60002292D1 (de) | 2003-05-28 |
| PT1140925E (pt) | 2003-08-29 |
| DE60002292T2 (de) | 2003-10-23 |
| CN1335845A (zh) | 2002-02-13 |
| CA2355308A1 (en) | 2000-07-13 |
| EP1140925A1 (en) | 2001-10-10 |
| JP2002534427A (ja) | 2002-10-15 |
| TW546299B (en) | 2003-08-11 |
| EP1140925B1 (en) | 2003-04-23 |
| AU2406700A (en) | 2000-07-24 |
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