ATE220690T1 - Katze-maus-heterohybridoma und genfragment, das für die konstant-region von katze-immunoglobulin codiert - Google Patents

Katze-maus-heterohybridoma und genfragment, das für die konstant-region von katze-immunoglobulin codiert

Info

Publication number
ATE220690T1
ATE220690T1 AT90115426T AT90115426T ATE220690T1 AT E220690 T1 ATE220690 T1 AT E220690T1 AT 90115426 T AT90115426 T AT 90115426T AT 90115426 T AT90115426 T AT 90115426T AT E220690 T1 ATE220690 T1 AT E220690T1
Authority
AT
Austria
Prior art keywords
gene fragment
cat
coding
amino acid
constant region
Prior art date
Application number
AT90115426T
Other languages
English (en)
Inventor
Hiroaki Maeda
Yasuyuki Eda
Kazuhiko Kimachi
Yoichi Ono
Sachio Tokiyoshi
Original Assignee
Chemo Sero Therapeut Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1208822A external-priority patent/JP2811086B2/ja
Priority claimed from JP25542489A external-priority patent/JP2811095B2/ja
Priority claimed from JP1344465A external-priority patent/JP2811102B2/ja
Application filed by Chemo Sero Therapeut Res Inst filed Critical Chemo Sero Therapeut Res Inst
Application granted granted Critical
Publication of ATE220690T1 publication Critical patent/ATE220690T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/166—Animal cells resulting from interspecies fusion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT90115426T 1989-08-10 1990-08-10 Katze-maus-heterohybridoma und genfragment, das für die konstant-region von katze-immunoglobulin codiert ATE220690T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1208822A JP2811086B2 (ja) 1989-08-10 1989-08-10 ネコ×マウスヘテロハイブリドーマおよびネコ免疫グロブリンλ鎖の定常領域をコードする遺伝子断片
JP25542489A JP2811095B2 (ja) 1989-09-30 1989-09-30 ネコ免疫グロブリンκ鎖の定常領域をコードする遺伝子断片およびマウス×ネコキメラ抗体
JP1344465A JP2811102B2 (ja) 1989-12-28 1989-12-28 ネコ免疫グロブリンγ鎖の定常領域をコードする遺伝子断片およびマウス×ネコキメラ抗体

Publications (1)

Publication Number Publication Date
ATE220690T1 true ATE220690T1 (de) 2002-08-15

Family

ID=27328935

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90115426T ATE220690T1 (de) 1989-08-10 1990-08-10 Katze-maus-heterohybridoma und genfragment, das für die konstant-region von katze-immunoglobulin codiert

Country Status (7)

Country Link
US (2) US5504198A (de)
EP (2) EP0417486B1 (de)
AT (1) ATE220690T1 (de)
AU (1) AU632843B2 (de)
CA (1) CA2022959C (de)
DE (1) DE69033987T2 (de)
ES (1) ES2180526T3 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69328799T2 (de) 1992-02-28 2000-10-26 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute, Kumamoto Anti-Felincalicivirus rekombinanter Antikörper und dafür kodierendes Gen
JP3919830B2 (ja) * 1992-11-28 2007-05-30 財団法人化学及血清療法研究所 抗ネコヘルペスウイルス−1組換え抗体および該抗体をコードする遺伝子断片
SG10201500957QA (en) * 2011-05-06 2015-04-29 Nvip Pty Ltd Anti-nerve growth factor antibodies and methods of preparing and using the same
AU2012252152B2 (en) * 2011-05-06 2016-07-07 Zoetis Services Llc Anti-nerve growth factor antibodies and methods of preparing and using the same
GB2561352B (en) * 2017-04-10 2023-01-18 Genome Res Ltd Animal models and therapeutic molecules
CN109627331B (zh) * 2019-01-22 2022-03-29 长春西诺生物科技有限公司 一种抗犬细小病毒抗体的重链、轻链可变区及基因工程抗体
CN110283246A (zh) * 2019-06-20 2019-09-27 长春西诺生物科技有限公司 一种抗猫细小病毒的猫源化基因工程抗体
CN110501509A (zh) * 2019-09-03 2019-11-26 长春西诺生物科技有限公司 一种抗猫细小病毒猫源化基因工程抗体elisa试剂盒及其检测方法
CN111909259A (zh) * 2020-07-10 2020-11-10 青岛博隆基因工程有限公司 猫细小病毒抗体序列、四肽链分子、球蛋白分子及应用
CN111848788B (zh) * 2020-07-10 2022-10-14 青岛博隆基因工程有限公司 猫杯状病毒抗体序列、四肽链分子、免疫球蛋白分子
CA3251683A1 (en) * 2022-02-18 2023-08-24 Adivo Gmbh FELINE ANTIBODY LIBRARIES
GB202209247D0 (en) * 2022-06-23 2022-08-10 Petmedix Ltd Animal models and therapeutic molecules
CN118599004B (zh) * 2024-06-11 2024-11-26 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 一种抗猫IgG单克隆抗体或其抗原结合片段及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DE3689123T2 (de) * 1985-11-01 1994-03-03 Xoma Corp Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung.
CA1340898C (en) * 1987-04-30 2000-02-15 The Wistar Institute Monoclonal antibodies against lymphoma-associated antigens, hybrid cell lines producing these antibodies, and use therefore
CA1339857C (en) * 1987-05-29 1998-05-05 Cecily Rou-Yun Sun Monoclonal antibodies to gp120 which neutraleze hiv-1
AU625613B2 (en) * 1988-01-05 1992-07-16 Novartis Ag Novel chimeric antibodies

Also Published As

Publication number Publication date
EP0417486A1 (de) 1991-03-20
US5504198A (en) 1996-04-02
EP0417486B1 (de) 2002-07-17
DE69033987D1 (de) 2002-08-22
ES2180526T3 (es) 2003-02-16
AU632843B2 (en) 1993-01-14
CA2022959A1 (en) 1991-02-11
EP1156064A2 (de) 2001-11-21
AU6081290A (en) 1991-02-14
US5880274A (en) 1999-03-09
DE69033987T2 (de) 2003-03-27
CA2022959C (en) 2001-03-20

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