ATE220690T1 - Katze-maus-heterohybridoma und genfragment, das für die konstant-region von katze-immunoglobulin codiert - Google Patents

Katze-maus-heterohybridoma und genfragment, das für die konstant-region von katze-immunoglobulin codiert

Info

Publication number
ATE220690T1
ATE220690T1 AT90115426T AT90115426T ATE220690T1 AT E220690 T1 ATE220690 T1 AT E220690T1 AT 90115426 T AT90115426 T AT 90115426T AT 90115426 T AT90115426 T AT 90115426T AT E220690 T1 ATE220690 T1 AT E220690T1
Authority
AT
Austria
Prior art keywords
gene fragment
cat
coding
amino acid
constant region
Prior art date
Application number
AT90115426T
Other languages
English (en)
Inventor
Hiroaki Maeda
Yasuyuki Eda
Kazuhiko Kimachi
Yoichi Ono
Sachio Tokiyoshi
Original Assignee
Chemo Sero Therapeut Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1208822A external-priority patent/JP2811086B2/ja
Priority claimed from JP25542489A external-priority patent/JP2811095B2/ja
Priority claimed from JP1344465A external-priority patent/JP2811102B2/ja
Application filed by Chemo Sero Therapeut Res Inst filed Critical Chemo Sero Therapeut Res Inst
Application granted granted Critical
Publication of ATE220690T1 publication Critical patent/ATE220690T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/166—Animal cells resulting from interspecies fusion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT90115426T 1989-08-10 1990-08-10 Katze-maus-heterohybridoma und genfragment, das für die konstant-region von katze-immunoglobulin codiert ATE220690T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1208822A JP2811086B2 (ja) 1989-08-10 1989-08-10 ネコ×マウスヘテロハイブリドーマおよびネコ免疫グロブリンλ鎖の定常領域をコードする遺伝子断片
JP25542489A JP2811095B2 (ja) 1989-09-30 1989-09-30 ネコ免疫グロブリンκ鎖の定常領域をコードする遺伝子断片およびマウス×ネコキメラ抗体
JP1344465A JP2811102B2 (ja) 1989-12-28 1989-12-28 ネコ免疫グロブリンγ鎖の定常領域をコードする遺伝子断片およびマウス×ネコキメラ抗体

Publications (1)

Publication Number Publication Date
ATE220690T1 true ATE220690T1 (de) 2002-08-15

Family

ID=27328935

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90115426T ATE220690T1 (de) 1989-08-10 1990-08-10 Katze-maus-heterohybridoma und genfragment, das für die konstant-region von katze-immunoglobulin codiert

Country Status (7)

Country Link
US (2) US5504198A (de)
EP (2) EP0417486B1 (de)
AT (1) ATE220690T1 (de)
AU (1) AU632843B2 (de)
CA (1) CA2022959C (de)
DE (1) DE69033987T2 (de)
ES (1) ES2180526T3 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2149182T3 (es) 1992-02-28 2000-11-01 Chemo Sero Therapeut Res Inst Anticuerpo recombinante dirigido contra el calicivirus felino y fragmentos de genes de este anticuerpo.
JP3919830B2 (ja) * 1992-11-28 2007-05-30 財団法人化学及血清療法研究所 抗ネコヘルペスウイルス−１組換え抗体および該抗体をコードする遺伝子断片
GB2504887B (en) * 2011-05-06 2016-02-03 Nvip Pty Ltd Anti-Nerve growth factor antibodies and methods of preparing and using the same
ES2704007T3 (es) * 2011-05-06 2019-03-13 Nexvet Australia Pty Ltd Anticuerpos anti-factor de crecimiento nervioso y procedimientos de preparación y uso de los mismos
GB2561352B (en) * 2017-04-10 2023-01-18 Genome Res Ltd Animal models and therapeutic molecules
CN109627331B (zh) * 2019-01-22 2022-03-29 长春西诺生物科技有限公司 一种抗犬细小病毒抗体的重链、轻链可变区及基因工程抗体
CN110283246A (zh) * 2019-06-20 2019-09-27 长春西诺生物科技有限公司 一种抗猫细小病毒的猫源化基因工程抗体
CN110501509A (zh) * 2019-09-03 2019-11-26 长春西诺生物科技有限公司 一种抗猫细小病毒猫源化基因工程抗体elisa试剂盒及其检测方法
CN111848788B (zh) * 2020-07-10 2022-10-14 青岛博隆基因工程有限公司 猫杯状病毒抗体序列、四肽链分子、免疫球蛋白分子
CN111909259A (zh) * 2020-07-10 2020-11-10 青岛博隆基因工程有限公司 猫细小病毒抗体序列、四肽链分子、球蛋白分子及应用
JP2025508603A (ja) * 2022-02-18 2025-03-26 アディヴォ ゲゼルシャフト ミット ベシュレンクテル ハフツング ネコ抗体ライブラリー
GB202209247D0 (en) * 2022-06-23 2022-08-10 Petmedix Ltd Animal models and therapeutic molecules
CN118599004B (zh) * 2024-06-11 2024-11-26 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 一种抗猫IgG单克隆抗体或其抗原结合片段及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DE3689123T2 (de) * 1985-11-01 1994-03-03 Xoma Corp Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung.
CA1340898C (en) * 1987-04-30 2000-02-15 The Wistar Institute Monoclonal antibodies against lymphoma-associated antigens, hybrid cell lines producing these antibodies, and use therefore
DE3853779T2 (de) * 1987-05-29 1995-09-07 Baylor College Medicine Hiv-1 neutralisierende monoklonale antikörper.
AU625613B2 (en) * 1988-01-05 1992-07-16 Novartis Ag Novel chimeric antibodies

Also Published As

Publication number Publication date
DE69033987D1 (de) 2002-08-22
US5504198A (en) 1996-04-02
AU6081290A (en) 1991-02-14
AU632843B2 (en) 1993-01-14
EP1156064A2 (de) 2001-11-21
DE69033987T2 (de) 2003-03-27
CA2022959C (en) 2001-03-20
EP0417486B1 (de) 2002-07-17
US5880274A (en) 1999-03-09
EP0417486A1 (de) 1991-03-20
CA2022959A1 (en) 1991-02-11
ES2180526T3 (es) 2003-02-16

Similar Documents

Publication Publication Date Title
DE69019447D1 (de) Hund-Maus-Heterohybridoma und für die konstante Region von Hunde-Immunglobulinen kodierendes Genfragment.
ATE220690T1 (de) Katze-maus-heterohybridoma und genfragment, das für die konstant-region von katze-immunoglobulin codiert
FR14C0070I1 (fr) Procede de la production des anticorps humanises
NO885326L (no) Human vevfaktor-beslektede dna-segmenter, polypeptider ogantistoffer.
ATE88572T1 (de) Antikoerper gegen polypeptide, die gegen peptide oder proteine mit mindestens teilweise bekannter aminosaeure oder kodierender nukleotidsequenz komplementaer sind und diesbezuegliches aufbauverfahren.
FR2715664B1 (fr) Baculovirus recombinant et son utilisation pour la production d'anticorps monoclonaux.
DE68922869D1 (de) Rezeptor-Proteine für humanen B-Zellen stimulierenden Faktor 2.
FI104262B (fi) Proteeinien, joissa on disulfidisillat, saannon parantaminen erityksessä
NO841277L (no) Nye faktor viii koagulerende polypeptider, og monoklonale antistoffer overfor disse
ES2140398T3 (es) Produccion de factor xiii a por tecnologia genetica.
ATE88754T1 (de) Transformierte hefen die lysozym produzieren, fuer diese transformation zu verwendende plasmide und deren verwendung.
DE69031726D1 (de) Antikörper, ihre Herstellung und Verwendung
ATE50458T1 (de) Bestimmung von fibrin mit fibrin-spezifischen antikoerpern.
DE69434741D1 (de) Reagenzien für die Diagnose von rheumatoiden Arthritis
PT93178A (pt) Agente proteico anticanceroso
ATE35427T1 (de) Rekombinante dna, damit transformierter mikroorganismus und dessen verwendung.
KR870010190A (ko) 펩타이드의 생산방법, 이 방법에 사용하기 위한 재조합 플라스미드 및 이 플라스미드로 형질 전환시킨 동물세포
DK515889A (da) Proteinoprensning

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties