ES2180526T3 - Heterohibridoma de gato-raton y fragmento genico que codifica para la region constante de una inmunoglobulina felina. - Google Patents
Heterohibridoma de gato-raton y fragmento genico que codifica para la region constante de una inmunoglobulina felina.Info
- Publication number
- ES2180526T3 ES2180526T3 ES90115426T ES90115426T ES2180526T3 ES 2180526 T3 ES2180526 T3 ES 2180526T3 ES 90115426 T ES90115426 T ES 90115426T ES 90115426 T ES90115426 T ES 90115426T ES 2180526 T3 ES2180526 T3 ES 2180526T3
- Authority
- ES
- Spain
- Prior art keywords
- constant region
- gen
- fragment
- feline immunoglobulin
- immunoglobulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- C12N5/166—Animal cells resulting from interspecies fusion
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
- C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
LA APLICACION REVELA UN FRAGMENTO DE GEN QUE CONSTA DE UNA CODIFICACION DE SECUENCIA DE DNA PARA UNA SECUENCIA DE AMINOACIDOS DE UNA REGION CONSTANTE DE UNA CADENA LAMBDA DE INMUNOGLOBULINA FELINA; UN FRAGMENTO DE GEN QUE CONSTA DE UNA CODIFICACION DE SECUENCIA DE DNA PARA UNA SECUENCIA DE AMINOACIDO DE UNA REGION CONSTANTE DE UNA CADENA X DE INMUNOGLOBULINA FELINA; UN FRAGMENTO DE GEN QUE CONSTA DE UNA CODIFICACION DE MOLECULA DE DNA PARA LA REGION CONSTANTE DE UNA CADENA GAMMA DE INMUNOGLOBULINA FELINA; UNA CODIFICACION DE MOLECULA DE DNA RECOMBINANTE PARA UNA SECUENCIA DE AMINOACIDO DE UN ANTICUERPO QUIMERICO DE GATO-RATON QUE CONSTA DE UNA CODIFICACION DE FRAGMENTO DE GEN PARA UNA SECUENCIA DE AMINOACIDO DE UNA REGION VARIABLE DE INMUNOGLOBULINA DE RATON Y UNA CODIFICACION DE FRAGMENTO DE GEN PARA UNA SECUENCIA DE AMINOACIDO DE UNA REGION CONSTANTE DE UNA INMUNOGLOBULINA FELINA, EN DONDE EL SEGUNDO FRAGMENTO DE GEN SE UNE AL LUGAR 3'' DEL PRIMER FRAGMENTO DE GEN; UN POLIPEPTIDO DE UN ANTICUERPO QUIMERICO DE GATO-RATON QUE SE EXPRESA A PARTIR DE UNA CELULA TRANSFORMADA POR UN VECTOR DE EXPRESION PARA CELULAS, EN DONDE SE INCORPORA DICHA CODIFICACION DE MOLECULA DE DNA RECOMBINANTE PARA UNA SECUENCIA DE AMINOACIDO DEL ANTICUERPO QUIMERICO DE GATO-RATON; UN HETEROHIBRIDOMA DE GATO-RATON QUE PRODUCE INMUNOGLOBULINA FELINA; Y UN PROCESO PARA LA PREPARACION DE UN GEN DE INMUNOGLOBULINA FELINA.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1208822A JP2811086B2 (ja) | 1989-08-10 | 1989-08-10 | ネコ×マウスヘテロハイブリドーマおよびネコ免疫グロブリンλ鎖の定常領域をコードする遺伝子断片 |
| JP25542489A JP2811095B2 (ja) | 1989-09-30 | 1989-09-30 | ネコ免疫グロブリンκ鎖の定常領域をコードする遺伝子断片およびマウス×ネコキメラ抗体 |
| JP1344465A JP2811102B2 (ja) | 1989-12-28 | 1989-12-28 | ネコ免疫グロブリンγ鎖の定常領域をコードする遺伝子断片およびマウス×ネコキメラ抗体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2180526T3 true ES2180526T3 (es) | 2003-02-16 |
Family
ID=27328935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90115426T Expired - Lifetime ES2180526T3 (es) | 1989-08-10 | 1990-08-10 | Heterohibridoma de gato-raton y fragmento genico que codifica para la region constante de una inmunoglobulina felina. |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5504198A (es) |
| EP (2) | EP0417486B1 (es) |
| AT (1) | ATE220690T1 (es) |
| AU (1) | AU632843B2 (es) |
| CA (1) | CA2022959C (es) |
| DE (1) | DE69033987T2 (es) |
| ES (1) | ES2180526T3 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69328799T2 (de) | 1992-02-28 | 2000-10-26 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute, Kumamoto | Anti-Felincalicivirus rekombinanter Antikörper und dafür kodierendes Gen |
| JP3919830B2 (ja) * | 1992-11-28 | 2007-05-30 | 財団法人化学及血清療法研究所 | 抗ネコヘルペスウイルス−１組換え抗体および該抗体をコードする遺伝子断片 |
| SG10201500957QA (en) * | 2011-05-06 | 2015-04-29 | Nvip Pty Ltd | Anti-nerve growth factor antibodies and methods of preparing and using the same |
| AU2012252152B2 (en) * | 2011-05-06 | 2016-07-07 | Zoetis Services Llc | Anti-nerve growth factor antibodies and methods of preparing and using the same |
| GB2561352B (en) * | 2017-04-10 | 2023-01-18 | Genome Res Ltd | Animal models and therapeutic molecules |
| CN109627331B (zh) * | 2019-01-22 | 2022-03-29 | 长春西诺生物科技有限公司 | 一种抗犬细小病毒抗体的重链、轻链可变区及基因工程抗体 |
| CN110283246A (zh) * | 2019-06-20 | 2019-09-27 | 长春西诺生物科技有限公司 | 一种抗猫细小病毒的猫源化基因工程抗体 |
| CN110501509A (zh) * | 2019-09-03 | 2019-11-26 | 长春西诺生物科技有限公司 | 一种抗猫细小病毒猫源化基因工程抗体elisa试剂盒及其检测方法 |
| CN111909259A (zh) * | 2020-07-10 | 2020-11-10 | 青岛博隆基因工程有限公司 | 猫细小病毒抗体序列、四肽链分子、球蛋白分子及应用 |
| CN111848788B (zh) * | 2020-07-10 | 2022-10-14 | 青岛博隆基因工程有限公司 | 猫杯状病毒抗体序列、四肽链分子、免疫球蛋白分子 |
| CA3251683A1 (en) * | 2022-02-18 | 2023-08-24 | Adivo Gmbh | FELINE ANTIBODY LIBRARIES |
| GB202209247D0 (en) * | 2022-06-23 | 2022-08-10 | Petmedix Ltd | Animal models and therapeutic molecules |
| CN118599004B (zh) * | 2024-06-11 | 2024-11-26 | 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) | 一种抗猫IgG单克隆抗体或其抗原结合片段及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DE3689123T2 (de) * | 1985-11-01 | 1994-03-03 | Xoma Corp | Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung. |
| CA1340898C (en) * | 1987-04-30 | 2000-02-15 | The Wistar Institute | Monoclonal antibodies against lymphoma-associated antigens, hybrid cell lines producing these antibodies, and use therefore |
| CA1339857C (en) * | 1987-05-29 | 1998-05-05 | Cecily Rou-Yun Sun | Monoclonal antibodies to gp120 which neutraleze hiv-1 |
| AU625613B2 (en) * | 1988-01-05 | 1992-07-16 | Novartis Ag | Novel chimeric antibodies |
-
1990
- 1990-08-09 CA CA002022959A patent/CA2022959C/en not_active Expired - Fee Related
- 1990-08-09 AU AU60812/90A patent/AU632843B2/en not_active Ceased
- 1990-08-10 EP EP90115426A patent/EP0417486B1/en not_active Expired - Lifetime
- 1990-08-10 DE DE69033987T patent/DE69033987T2/de not_active Expired - Fee Related
- 1990-08-10 AT AT90115426T patent/ATE220690T1/de not_active IP Right Cessation
- 1990-08-10 ES ES90115426T patent/ES2180526T3/es not_active Expired - Lifetime
- 1990-08-10 EP EP01118802A patent/EP1156064A2/en not_active Withdrawn
-
1994
- 1994-05-23 US US08/247,486 patent/US5504198A/en not_active Expired - Lifetime
-
1995
- 1995-11-17 US US08/559,947 patent/US5880274A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0417486A1 (en) | 1991-03-20 |
| US5504198A (en) | 1996-04-02 |
| EP0417486B1 (en) | 2002-07-17 |
| DE69033987D1 (de) | 2002-08-22 |
| AU632843B2 (en) | 1993-01-14 |
| CA2022959A1 (en) | 1991-02-11 |
| EP1156064A2 (en) | 2001-11-21 |
| AU6081290A (en) | 1991-02-14 |
| US5880274A (en) | 1999-03-09 |
| ATE220690T1 (de) | 2002-08-15 |
| DE69033987T2 (de) | 2003-03-27 |
| CA2022959C (en) | 2001-03-20 |
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