ATE220715T1 - Verfahren zur selektiven vermehrung von cd34 positiven zellen - Google Patents

Verfahren zur selektiven vermehrung von cd34 positiven zellen

Info

Publication number
ATE220715T1
ATE220715T1 AT92923129T AT92923129T ATE220715T1 AT E220715 T1 ATE220715 T1 AT E220715T1 AT 92923129 T AT92923129 T AT 92923129T AT 92923129 T AT92923129 T AT 92923129T AT E220715 T1 ATE220715 T1 AT E220715T1
Authority
AT
Austria
Prior art keywords
positive cells
stem cells
selective propagation
cells
propagation
Prior art date
Application number
AT92923129T
Other languages
English (en)
Inventor
Shelly Heimfeld
Ronald J Berenson
Ruigao Fei
Randal A Goffe
Dale R Peterson
Christopher H Porter
Original Assignee
Nexell Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nexell Therapeutics Inc filed Critical Nexell Therapeutics Inc
Application granted granted Critical
Publication of ATE220715T1 publication Critical patent/ATE220715T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5002—Partitioning blood components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Secondary Cells (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT92923129T 1991-10-23 1992-10-22 Verfahren zur selektiven vermehrung von cd34 positiven zellen ATE220715T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78048891A 1991-10-23 1991-10-23
PCT/US1992/009019 WO1993008268A1 (en) 1991-10-23 1992-10-22 Methods for selectively expanding stem cells

Publications (1)

Publication Number Publication Date
ATE220715T1 true ATE220715T1 (de) 2002-08-15

Family

ID=25119727

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92923129T ATE220715T1 (de) 1991-10-23 1992-10-22 Verfahren zur selektiven vermehrung von cd34 positiven zellen

Country Status (8)

Country Link
EP (1) EP0614485B1 (de)
JP (1) JPH07503127A (de)
AT (1) ATE220715T1 (de)
CA (1) CA2122141C (de)
DE (1) DE69232682T2 (de)
DK (1) DK0614485T3 (de)
ES (1) ES2180539T3 (de)
WO (1) WO1993008268A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5554512A (en) * 1993-05-24 1996-09-10 Immunex Corporation Ligands for flt3 receptors
NZ314644A (en) 1993-05-24 2000-11-24 Immunex Corp Use of flt3-ligands as a growth stimulator of stem cells in the transplantation of tissue
US5409813A (en) * 1993-09-30 1995-04-25 Systemix, Inc. Method for mammalian cell separation from a mixture of cell populations
US6190655B1 (en) 1993-12-03 2001-02-20 Immunex Corporation Methods of using Flt-3 ligand for exogenous gene transfer
US7294331B2 (en) 1994-03-07 2007-11-13 Immunex Corporation Methods of using flt3-ligand in hematopoietic cell transplantation
US5580724A (en) * 1994-03-25 1996-12-03 Board Of Regents, The University Of Texas System Differential expansion of fetal stem cells in maternal circulation for use in prenatal genetic analysis
US5972627A (en) * 1994-06-15 1999-10-26 Systemix, Inc. Method of purifying a population of cells enriched for dendritic and/or lymphoid progenitors and populations of cells obtained thereby
US5985660A (en) * 1994-06-15 1999-11-16 Systemix, Inc. Method of identifying biological response modifiers involved in dendritic and/or lymphoid progenitor cell proliferation and/or differentiation
US5663051A (en) * 1994-08-31 1997-09-02 Activated Cell Therapy, Inc. Separation apparatus and method
US5648223A (en) * 1994-08-31 1997-07-15 Activated Cell Therapy, Inc. Methods for enriching breast tumor cells
US5840502A (en) * 1994-08-31 1998-11-24 Activated Cell Therapy, Inc. Methods for enriching specific cell-types by density gradient centrifugation
US5646004A (en) * 1994-08-31 1997-07-08 Activated Cell Therapy, Inc. Methods for enriching fetal cells from maternal body fluids
US5474687A (en) * 1994-08-31 1995-12-12 Activated Cell Therapy, Inc. Methods for enriching CD34+ human hematopoietic progenitor cells
US5674750A (en) * 1995-05-19 1997-10-07 T. Breeders Continuous selective clonogenic expansion of relatively undifferentiated cells
US5728581A (en) * 1995-06-07 1998-03-17 Systemix, Inc. Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein
US6015554A (en) * 1995-06-07 2000-01-18 Systemix, Inc. Method of reconstituting human lymphoid and dendritic cells
US7150992B1 (en) 1995-10-04 2006-12-19 Innunex Corporation Methods of preparing dendritic cells with flt3-ligand and antigen
WO1997012633A1 (en) 1995-10-04 1997-04-10 Immunex Corporation Dendritic cell stimulatory factor
US7361330B2 (en) 1995-10-04 2008-04-22 Immunex Corporation Methods of using flt3-ligand in the treatment of fibrosarcoma
WO1997026326A1 (en) * 1996-01-16 1997-07-24 Depuy Orthopaedics, Inc. Isolation of precursor cells from hematopoietic and non-hematopoietic tissues and their use
US6429012B1 (en) 1997-10-06 2002-08-06 Viacell, Inc. Cell population containing non-fetal hemangioblasts and method for producing same
EP1070757B1 (de) 1998-04-08 2005-02-02 Shionogi & Co., Ltd. Verfahren um Vorläuferzellen von Osteoklasten zu isolieren und ihre Differenzierung in Osteoklasten zu induzieren.
JP2002523039A (ja) * 1998-08-24 2002-07-30 ティー．ブリーダーズ，インコーポレイテッド 非胎児血管芽細胞を含む細胞集団、およびその生産方法
ES2616337T3 (es) 2003-12-12 2017-06-12 Government Of The United States Of America, As Repr. By The Secr. Of The Dept. Of Health And Human Services And His Successors Un epítopo de linfocito T citotóxico humano y su epítopo agonista del número no variable de secuencias de repetición en tándem de MUC-1
EP1773981A1 (de) * 2004-07-12 2007-04-18 Sorin Group Italia S.R.L. Vorrichtung und verfahren zur anzucht menschlicher zellen
US8741639B2 (en) 2008-11-14 2014-06-03 Dnavec Corporation Method for producing dendritic cells

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5087570A (en) * 1988-05-10 1992-02-11 Weissman Irving L Homogeneous mammalian hematopoietic stem cell composition
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5622853A (en) * 1990-05-01 1997-04-22 Becton Dickinson And Company T lymphocyte precursor
US5154921A (en) * 1990-07-13 1992-10-13 Dana-Farber Cancer Institute, Inc. Promotion of maturation of hematopoietic progenitor cells

Also Published As

Publication number Publication date
EP0614485B1 (de) 2002-07-17
CA2122141C (en) 2007-07-17
WO1993008268A1 (en) 1993-04-29
DE69232682T2 (de) 2003-03-13
DE69232682D1 (de) 2002-08-22
DK0614485T3 (da) 2002-10-28
EP0614485A1 (de) 1994-09-14
CA2122141A1 (en) 1993-04-29
JPH07503127A (ja) 1995-04-06
ES2180539T3 (es) 2003-02-16

Similar Documents

Publication Publication Date Title
ATE220715T1 (de) Verfahren zur selektiven vermehrung von cd34 positiven zellen
ATE397752T1 (de) Verfahren und verwendung von anordungen von proteinfixierungsmitteln
SE9404250D0 (sv) Affinity separation method
WO2001071732A3 (de) Porous ferro- or ferrimagnetic glass particles for isolating molecules
DE3382722D1 (de) Mikroporöses blattförmiges Material, Verfahren zur Herstellung und damit hergestellte Gegenstände.
DE69841479D1 (de) Verfahren zur gesichtsbildkorrektuer, simulationsverfahren für make-up, make-up-verfahren, unterstützungsverfahren für make-up, grundierungstransferfilm
ES2124400T3 (es) Separacion de proteinas.
DE68911508D1 (de) Verfahren zur herstellung von linear ausgedehnten polyalkylenpolyaminen.
NL194720B (nl) Werkwijze ter vervaardiging van een asymmetrisch membraan.
DE3579850D1 (de) Verfahren zur herstellung von rohren aus mikriporoesem isoliermaterial und danach hergestellte rohre.
TR200001313T2 (tr) Protein etkileşimlerini ve fonksiyonel ilişkileri kaydeden tarama sistemleri
DE69002941D1 (de) Verfahren zur entfernung von quecksilber und gegebenenfalls arsen aus kohlenwasserstoffen.
ES2169025T3 (es) Compuestos, vectores y procedimiento para expresar fosfolipasa a2 citosolica humana.
DE69633595D1 (de) Verfahren und Gerät zur Erweiterung und Wiedergewinnung von ähnlichen Zeichenfolgen.
ATE126531T1 (de) Verfahren zur gewinnung von natürlich hergestelltem chymosin.
FI973351A0 (fi) Menetelmä kovien vaahtojen valmistamiseksi ja niistä valmistetut tuotteet
DE3869690D1 (de) Verfahren zur magnetisierung von bohrlochrohren.
DE3887938D1 (de) Verfahren zur Gastrennung.
TR199600558A2 (tr) Tütün kümesi hazirlamaya ve genlestirmeye mahsus usul ve cihaz.
ATE522604T1 (de) Verfahren zur herstellung von proteinen durch elektropulsierung
AR242832A1 (es) Polidomas productores de anticuerpos monoclonales hibridos biespecificos contra la fibrina y uk y/o pro uk y metodo para producirlos.
DE69019243D1 (de) Verfahren zur chromatographischen Trennung.
DE59802167D1 (de) Verfahren zur herstellung von expandierten polyolefin-partikel n
DE69319715D1 (de) Verfahren zur Analyse, Abtrennung und Mikroverkapselung von zellulären Elementen
ATA140395A (de) Verfahren zur selektiven abtrennung von verfahren zur selektiven abtrennung von morpholin morpholin

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0614485

Country of ref document: EP

REN Ceased due to non-payment of the annual fee