ATE220916T1 - Ligand antagonisten zur behandlung von brustkrebs - Google Patents

Ligand antagonisten zur behandlung von brustkrebs

Info

Publication number
ATE220916T1
ATE220916T1 AT94909578T AT94909578T ATE220916T1 AT E220916 T1 ATE220916 T1 AT E220916T1 AT 94909578 T AT94909578 T AT 94909578T AT 94909578 T AT94909578 T AT 94909578T AT E220916 T1 ATE220916 T1 AT E220916T1
Authority
AT
Austria
Prior art keywords
receptor
ligands
growth
hormone
novel
Prior art date
Application number
AT94909578T
Other languages
English (en)
Inventor
Germaine Fuh
James A Wells
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE220916T1 publication Critical patent/ATE220916T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT94909578T 1993-02-19 1994-02-09 Ligand antagonisten zur behandlung von brustkrebs ATE220916T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2032793A 1993-02-19 1993-02-19
PCT/US1994/001444 WO1994019004A1 (en) 1993-02-19 1994-02-09 Ligand antagonists for treatment of breast cancer

Publications (1)

Publication Number Publication Date
ATE220916T1 true ATE220916T1 (de) 2002-08-15

Family

ID=21798003

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94909578T ATE220916T1 (de) 1993-02-19 1994-02-09 Ligand antagonisten zur behandlung von brustkrebs

Country Status (9)

Country Link
EP (1) EP0684835B1 (de)
JP (1) JP3983280B2 (de)
AT (1) ATE220916T1 (de)
CA (1) CA2154163C (de)
DE (1) DE69431041T2 (de)
DK (1) DK0684835T3 (de)
ES (1) ES2180571T3 (de)
PT (1) PT684835E (de)
WO (1) WO1994019004A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
ATE366114T1 (de) * 1998-05-12 2007-07-15 Greenville Hospital System Verwendung von anti-prolaktin agentien zur behandlung von krebs
JP4593754B2 (ja) * 2000-10-13 2010-12-08 一般財団法人 化学物質評価研究機構 化学物質の50%阻害濃度決定方法
FR2833011B1 (fr) * 2001-12-04 2004-10-29 Univ Claude Bernard Lyon Nouvelle proteine a activite inhibitrice de l'il-6
JP4912894B2 (ja) 2004-02-19 2012-04-11 イェール ユニバーシティー プロテオーム技術を使用した癌タンパク質バイオマーカーの同定

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992019736A1 (en) * 1991-05-01 1992-11-12 Ohio University Growth hormone antagonists
JP3417558B2 (ja) * 1991-05-10 2003-06-16 ジェネンテク,インコーポレイテッド 配位子作用薬および拮抗薬の選択

Also Published As

Publication number Publication date
WO1994019004A1 (en) 1994-09-01
EP0684835A1 (de) 1995-12-06
JP3983280B2 (ja) 2007-09-26
CA2154163A1 (en) 1994-09-01
DE69431041D1 (de) 2002-08-29
ES2180571T3 (es) 2003-02-16
DK0684835T3 (da) 2002-11-11
JPH08506591A (ja) 1996-07-16
AU685434B2 (en) 1998-01-22
EP0684835B1 (de) 2002-07-24
DE69431041T2 (de) 2003-02-06
AU6237894A (en) 1994-09-14
CA2154163C (en) 2009-12-01
HK1010990A1 (en) 1999-07-02
PT684835E (pt) 2002-12-31

Similar Documents

Publication Publication Date Title
ATE196548T1 (de) Auswählen von agonisten und antagonisten von liganden
LESNIAK et al. Human growth hormone radioreceptor assay using cultured human lymphocytes
Ehrlich et al. Mixing two monoclonal antibodies yields enhanced affinity for antigen.
Edmundson et al. A search for site-filling ligands in the Mcg Bence-Jones dimer: crystal binding studies of fluorescent compounds
SOAMES et al. Interactions between human complement components factor H, factor I and C3b
ATE184019T1 (de) Monoklonale antikörper gegen rezeptor-induzierte bindungsstellen
DE2717741C2 (de)
KR850004594A (ko) 펩타이드의 제조방법
DE69636677D1 (de) Kristalle der mit einem Ligand komplexierten Ligandenbindedomäne des Schilddrüsenhormonrezeptors
TR200002257T2 (tr) Nükleer reseptör ligandları ve ligand bağlanma domainleri.
EP0048357A1 (de) Verfahren zum Bestimmen eines Antigens in einer Lösung
DE69511399D1 (de) Isolierte, von mage-3 abgeleitete peptide, welche mit hla-a2 molekülen komplexieren
Perkins A study of the amino-acid complexes formed by metals of Group II of the periodic classification
Haurowitz et al. The specificity of antibodies to antigens containing two different determinant groups
ATE220916T1 (de) Ligand antagonisten zur behandlung von brustkrebs
TW272197B (de)
DE69030494T2 (de) Karzinomverwandtes haptoglobin (hpr)
Moyle et al. Detection of conformational changes in human chorionic gonadotropin upon binding to rat gonadal receptors.
Heusser et al. Monoclonal antibodies to human renin: properties and applications
Whitla et al. The crystal structure of [PtCl (OMe)(dicyclopentadiene)]
Baran et al. Characterization of the soluble murine IL-2R and estimation of its affinity for IL-2.
KR850002399A (ko) 액체 서방출성 제형의 제조방법
Lien et al. The mechanism of cobalamin binding to hog intrinsic factor
Hong et al. Univalence of half-molecules of rabbit antibody
Everhart Antibody response of goldfish to a protein immunogen and to haptenic determinants

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee