ATE221057T1 - Quinoneverbindung, seine herstellung und anwendung. - Google Patents
Quinoneverbindung, seine herstellung und anwendung.Info
- Publication number
- ATE221057T1 ATE221057T1 AT96927194T AT96927194T ATE221057T1 AT E221057 T1 ATE221057 T1 AT E221057T1 AT 96927194 T AT96927194 T AT 96927194T AT 96927194 T AT96927194 T AT 96927194T AT E221057 T1 ATE221057 T1 AT E221057T1
- Authority
- AT
- Austria
- Prior art keywords
- optionally substituted
- pct
- group
- sec
- substituted hydrocarbon
- Prior art date
Links
- -1 QUINONE COMPOUND Chemical class 0.000 title 1
- AZQWKYJCGOJGHM-UHFFFAOYSA-N para-benzoquinone Natural products O=C1C=CC(=O)C=C1 AZQWKYJCGOJGHM-UHFFFAOYSA-N 0.000 title 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000000687 hydroquinonyl group Chemical class C1(O)=C(C=C(O)C=C1)* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000005415 substituted alkoxy group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C07D295/116—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings with the doubly bound oxygen or sulfur atoms directly attached to a carbocyclic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21162995 | 1995-08-21 | ||
| PCT/JP1996/002313 WO1997007109A1 (en) | 1995-08-21 | 1996-08-19 | Quinone compound, its production and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE221057T1 true ATE221057T1 (de) | 2002-08-15 |
Family
ID=16608945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96927194T ATE221057T1 (de) | 1995-08-21 | 1996-08-19 | Quinoneverbindung, seine herstellung und anwendung. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6011046A (de) |
| EP (1) | EP0846109B1 (de) |
| AT (1) | ATE221057T1 (de) |
| AU (1) | AU6709896A (de) |
| CA (1) | CA2227985A1 (de) |
| DE (1) | DE69622569T2 (de) |
| WO (1) | WO1997007109A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
| US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
| EP1879875A1 (de) * | 2005-04-22 | 2008-01-23 | Wyeth | Kristallformen von {[(2r)-7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methyl}amin-hydrochlorid |
| EA035619B1 (ru) | 2005-06-01 | 2020-07-16 | ПиТиСи ТЕРАПЬЮТИКС, ИНК. | Композиции для использования в способе лечения митохондриальных нарушений |
| JP2009508867A (ja) * | 2005-09-15 | 2009-03-05 | エジソン ファーマシューティカルズ， インコーポレイテッド | ミトコンドリア病および関連した様態の治療ならびにエネルギーバイオマーカーの調節のための酸化還元活性治療剤のテイル改変体 |
| EP1986636B1 (de) | 2006-02-22 | 2013-04-24 | Edison Pharmaceuticals, Inc. | Phenol- und 1,4-benzochinon-derivate zur verwendung in der behandlung von erkrankungen der mitochondrien |
| US7618350B2 (en) * | 2007-06-04 | 2009-11-17 | Icon Ip, Inc. | Elliptical exercise machine with adjustable ramp |
| PL2220030T3 (pl) | 2007-11-06 | 2016-07-29 | Bioelectron Tech Corp | Pochodne 4-(p-chinonylo)-2-hydroksybutanamidu do leczenia chorób mitochondrialnych |
| WO2009111576A2 (en) | 2008-03-05 | 2009-09-11 | Edison Pharmaceuticals, Inc. | 2-SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES |
| EP2344142B1 (de) | 2008-09-10 | 2024-06-26 | PTC Therapeutics, Inc. | Behandlung von pervasiven entwicklungsstörungen mit redox-aktiven therapeutika |
| HUE058877T2 (hu) | 2014-12-16 | 2022-09-28 | Ptc Therapeutics Inc | (R)-2-hidroxi-2-metil-4-(2,4,5-trimetil-3,6-dioxociklohexa-1,4-dienil)butánamid polimorf és amorf alakjai |
| EP3389646A1 (de) | 2015-12-17 | 2018-10-24 | BioElectron Technology Corporation | Flouralkyl, flouralkoxy, phenoxy, heteroaryloxy, alkoxy und amin-1,4-benzochinon-derivate zur behandlung von oxidativen stresserkrankungen |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58177934A (ja) * | 1982-04-13 | 1983-10-18 | Takeda Chem Ind Ltd | ベンゾキノン誘導体 |
| CA1338012C (en) * | 1987-04-27 | 1996-01-30 | John Michael Mccall | Pharmaceutically active amines |
| JPH08768B2 (ja) * | 1989-08-24 | 1996-01-10 | 武田薬品工業株式会社 | 神経成長因子分泌誘導剤 |
| US5283546A (en) * | 1991-05-13 | 1994-02-01 | Motorola, Inc. | Vandal-resistant call box |
| FR2681324B1 (fr) * | 1991-09-18 | 1993-10-29 | Adir Cie | Nouveaux derives de la trimetazidine, leur procede de preparation et les compositions pharmaceutiques les contenant. |
| EP0576766A1 (de) * | 1992-06-29 | 1994-01-05 | Novo Nordisk A/S | Propanolamin-Derivate, ihre Herstellung und Verwendung |
| NZ290946A (en) * | 1994-08-12 | 1997-12-19 | Toyama Chemical Co Ltd | Quinolone- or naphthyridone-carboxylic acid derivatives |
-
1996
- 1996-08-19 WO PCT/JP1996/002313 patent/WO1997007109A1/en not_active Ceased
- 1996-08-19 AT AT96927194T patent/ATE221057T1/de not_active IP Right Cessation
- 1996-08-19 AU AU67098/96A patent/AU6709896A/en not_active Abandoned
- 1996-08-19 DE DE69622569T patent/DE69622569T2/de not_active Expired - Fee Related
- 1996-08-19 CA CA002227985A patent/CA2227985A1/en not_active Abandoned
- 1996-08-19 US US08/727,599 patent/US6011046A/en not_active Expired - Fee Related
- 1996-08-19 EP EP96927194A patent/EP0846109B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2227985A1 (en) | 1997-02-27 |
| EP0846109B1 (de) | 2002-07-24 |
| DE69622569D1 (de) | 2002-08-29 |
| AU6709896A (en) | 1997-03-12 |
| WO1997007109A1 (en) | 1997-02-27 |
| US6011046A (en) | 2000-01-04 |
| EP0846109A1 (de) | 1998-06-10 |
| DE69622569T2 (de) | 2003-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |