ATE221779T1 - Behandlung und vorbeugung von erhöhten lyso-paf- spiegel mediierten mentalen erkrankungen mit paf- antagonisten - Google Patents

Behandlung und vorbeugung von erhöhten lyso-paf- spiegel mediierten mentalen erkrankungen mit paf- antagonisten

Info

Publication number
ATE221779T1
ATE221779T1 AT91118745T AT91118745T ATE221779T1 AT E221779 T1 ATE221779 T1 AT E221779T1 AT 91118745 T AT91118745 T AT 91118745T AT 91118745 T AT91118745 T AT 91118745T AT E221779 T1 ATE221779 T1 AT E221779T1
Authority
AT
Austria
Prior art keywords
paf
lyso
treatment
antagonists
ginkgolide
Prior art date
Application number
AT91118745T
Other languages
English (en)
Inventor
Ruth-Maria Korth
Original Assignee
Ruth-Maria Korth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8207297&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE221779(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ruth-Maria Korth filed Critical Ruth-Maria Korth
Application granted granted Critical
Publication of ATE221779T1 publication Critical patent/ATE221779T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Anesthesiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT91118745T 1991-11-04 1991-11-04 Behandlung und vorbeugung von erhöhten lyso-paf- spiegel mediierten mentalen erkrankungen mit paf- antagonisten ATE221779T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91118745A EP0540767B9 (de) 1991-11-04 1991-11-04 Behandlung und Vorbeugung von erhöhten Lyso-PAF-Spiegel mediierten mentalen Erkrankungen mit PAF-Antagonisten

Publications (1)

Publication Number Publication Date
ATE221779T1 true ATE221779T1 (de) 2002-08-15

Family

ID=8207297

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91118745T ATE221779T1 (de) 1991-11-04 1991-11-04 Behandlung und vorbeugung von erhöhten lyso-paf- spiegel mediierten mentalen erkrankungen mit paf- antagonisten

Country Status (6)

Country Link
US (3) US5346894A (de)
EP (1) EP0540767B9 (de)
JP (1) JPH06305981A (de)
AT (1) ATE221779T1 (de)
DE (2) DE540767T1 (de)
ES (1) ES2181665T3 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5895785A (en) * 1987-10-20 1999-04-20 Ruth Korth Treatment and prevention of disorders mediated by LA-paf or endothelial cells
US5530023A (en) * 1987-10-20 1996-06-25 Korth; Ruth Production of binding sites for PAF, PAF analogues and PAF antagonists in endothelial cells
US6274621B1 (en) 1995-11-09 2001-08-14 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Ginkgolides for inhibition of membrane expression of benzodiazepine receptors
US5854279A (en) * 1996-06-04 1998-12-29 Eisai Co., Ltd Therapeutic agent for dermatosis
US7078434B1 (en) 1999-08-12 2006-07-18 Societe De Conseils De Recherches Et D'applications Scientifiques Sas Use of Ginkgo extract
JP4733801B2 (ja) * 1999-08-23 2011-07-27 丸善製薬株式会社 エストロゲン様作用剤および皮膚化粧料
US6583152B2 (en) * 2001-04-30 2003-06-24 Dexgen Pharmaceuticals, Inc. Composition for reducing the risk or progression of cardiovascular diseases
US20050032713A1 (en) * 2002-03-27 2005-02-10 Wurtman Richard J. Platelet-activating factor antagonists as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agents
US11039997B2 (en) 2005-12-27 2021-06-22 Ruth-Maria Korth Cosmetic, dermatic, protective compositions comprising phospholipids, lecithins with peptides and at least one acetylating compound
DE102005062417A1 (de) * 2005-12-27 2007-08-23 Korth, Ruth-Maria, Dr.med. Kompositionen mit spezifischen und unspezifischen Lipidantagonisten
RU2342131C2 (ru) * 2007-01-29 2008-12-27 Алена Борисовна Конькова-Рейдман Применение цитофлавина для лечения клещевых нейроинфекций
JP5982676B2 (ja) * 2011-02-28 2016-08-31 学校法人 いわき明星大学 抗ｐａｆ活性を有するビオチニル化ペプチド化合物
DE202011108417U1 (de) * 2011-11-29 2012-03-01 Ruth-Maria Korth Örtliche und dietätische Kompositionen ohne Etherlipide, Etherphospholipide, Alkylradikale, die geeignet sind für sensible Personen
CN108096241B (zh) * 2017-11-24 2020-06-16 江苏康缘药业股份有限公司 银杏内酯组合物的医药用途
ES2958082T3 (es) 2019-01-15 2024-02-01 Dr Willmar Schwabe Gmbh & Co Kg Procedimiento para la producción de comprimidos de fácil toma con extracto seco de hojas de Ginkgo biloba
DE202019003092U1 (de) 2019-07-24 2020-02-27 Ruth-Maria Korth Test zur Bestimmung von Proteophospholipiden und FIDA-Formeln zur Bestimmung von Schutzfaktoren , die mit Substraten auszugleichen sind

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8705890A3 (es) * 1971-06-18 1986-11-16 Yoshitomi Pharmaceutical Un metodo de preparacion de compuesto de triazolotienodiaze-pina
DE3338995A1 (de) * 1983-10-27 1985-05-09 Dr. Willmar Schwabe GmbH & Co, 7500 Karlsruhe Bilobalid enthaltende arzneimittel
DE2732921A1 (de) * 1977-07-21 1979-02-08 Boehringer Sohn Ingelheim Neue substituierte 1-acyl-piperidino- bzw. -piperazino-4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4- diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
US4183912A (en) * 1978-01-16 1980-01-15 American Home Products Corporation Inhalation therapy for relieving bronchial spasm using quaternary salts of promethazine
DE2830782A1 (de) * 1978-07-13 1980-01-24 Boehringer Sohn Ingelheim Neue substituierte 4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4-diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
JPS6045518A (ja) * 1983-08-22 1985-03-12 Takeda Chem Ind Ltd 抗シヨツク剤
US4540709A (en) * 1983-10-13 1985-09-10 Merck & Co., Inc. Method for treatment of diseases mediated by PAF using 5-allyl-2-(3,4-Dimethoxyphenyl)-3a,α-methoxy-3-methyl-2,3,3a,6-tetrahydro-6-oxobenzofuran
US4595693A (en) * 1984-06-04 1986-06-17 Merck & Co., Inc. Method of use of 2,5-diaryl tetrahydrofurans and analogs thereof as PAF-antagonists
GB8418424D0 (en) * 1984-07-19 1984-08-22 Scras Inhibition of platelets aggregation
DE3435973A1 (de) * 1984-10-01 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
DE3502392A1 (de) * 1985-01-25 1986-07-31 Boehringer Ingelheim KG, 6507 Ingelheim Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
ES2037013T3 (es) * 1986-01-21 1993-06-16 Boehringer Ingelheim Kg Procedimiento para preparar tieno-1,4-diazepinas.
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
JPS63225373A (ja) * 1986-07-24 1988-09-20 Sumitomo Pharmaceut Co Ltd 新規チアゾリジン−４−オン誘導体およびその酸付加塩
YU136287A (en) * 1986-07-25 1990-06-30 Boehringer Kg Process for preparing new 1,4 benzodiazepines
DE3735524C2 (de) * 1986-10-21 1996-07-11 Korth Ruth Maria Verfahren zur Bestimmung des paf-Acether- oder Peak X-Gehaltes von Blut
DE3710921C2 (de) * 1986-10-21 1996-09-26 Korth Ruth Verwendung der Gingkolide BN 52020, BN 52021 und BN 52063 zur Behandlung von Arteriosklerose
DE3716004A1 (de) * 1987-05-13 1988-11-24 Bischof Hubert Sicherheitsfolie, deren verwendung und mit dieser hergestelltes sicherheitsglas
DE3735525C2 (de) * 1987-10-20 1997-02-20 Korth Ruth Maria Verfahren zur Bestimmung der Wirksamkeit von paf-Acether-Rezeptor-Antagonisten
DE4244265C2 (de) * 1992-12-28 1999-08-12 Korth Ruth Maria Verwendung von Paf-Antagonisten gegen die neue Ausbildung von Paf-Bindungsstellen auf endothelialen Zellen zur Behandlung oder Vorbeugung des Hyperinsulinismus
GB8725871D0 (en) * 1987-11-04 1987-12-09 Scras Ginkgolide derivatives
DE8716044U1 (de) * 1987-12-04 1988-03-24 Lewitz, Reinwald, 3100 Celle Einbau-Häng-Globus
US5334592A (en) * 1988-04-27 1994-08-02 Schering Corporation Certain PAF antagonist antihistamine combinations and methods
US5147864A (en) * 1988-12-19 1992-09-15 American Cyanamid Company Bis-arylphosphate ester antagonists of platelet activating factor
US5240922A (en) * 1989-05-05 1993-08-31 Northern Sydney Area Health Service Fertility enhancement
IT1238684B (it) * 1990-02-09 1993-09-01 Indena Spa Derivati del bilobalide,loro usi e formulazioni che li contegono
DE69132379T2 (de) * 1990-06-06 2001-03-01 Ruth-Maria Korth Behandlung von Erkrankungen mit Paf-Antagonisten und Verfahren zur Bestimmung deren Wirksamkeit

Also Published As

Publication number Publication date
JPH06305981A (ja) 1994-11-01
EP0540767B9 (de) 2004-12-22
DE69133083D1 (de) 2002-09-12
US5346894A (en) 1994-09-13
DE540767T1 (de) 2001-10-25
ES2181665T3 (es) 2003-03-01
EP0540767B1 (de) 2002-08-07
DE69133083T2 (de) 2003-05-08
US5852052A (en) 1998-12-22
US5605927A (en) 1997-02-25
DE69133083C5 (de) 2007-05-31
EP0540767A1 (de) 1993-05-12

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