ATE258067T1 - Kombinationspräparat zur behandlung der parkinsonschen krankheit, das selektive nmda- antagonisten enthält - Google Patents

Kombinationspräparat zur behandlung der parkinsonschen krankheit, das selektive nmda- antagonisten enthält

Info

Publication number
ATE258067T1
ATE258067T1 AT95918111T AT95918111T ATE258067T1 AT E258067 T1 ATE258067 T1 AT E258067T1 AT 95918111 T AT95918111 T AT 95918111T AT 95918111 T AT95918111 T AT 95918111T AT E258067 T1 ATE258067 T1 AT E258067T1
Authority
AT
Austria
Prior art keywords
parkinson
treatment
selective nmda
combination drug
nmda antagonists
Prior art date
Application number
AT95918111T
Other languages
English (en)
Inventor
Bertrand L Chenard
Frank S Menniti
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE258067T1 publication Critical patent/ATE258067T1/de

Links

Classifications

    • G—PHYSICS
    • G10—MUSICAL INSTRUMENTS; ACOUSTICS
    • G10H—ELECTROPHONIC MUSICAL INSTRUMENTS; INSTRUMENTS IN WHICH THE TONES ARE GENERATED BY ELECTROMECHANICAL MEANS OR ELECTRONIC GENERATORS, OR IN WHICH THE TONES ARE SYNTHESISED FROM A DATA STORE
    • G10H5/00—Instruments in which the tones are generated by means of electronic generators
    • G10H5/10—Instruments in which the tones are generated by means of electronic generators using generation of non-sinusoidal basic tones, e.g. saw-tooth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Multimedia (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Hydrogenated Pyridines (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
AT95918111T 1995-05-26 1995-05-26 Kombinationspräparat zur behandlung der parkinsonschen krankheit, das selektive nmda- antagonisten enthält ATE258067T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IB1995/000398 WO1996037226A2 (en) 1995-05-26 1995-05-26 Combinations for the treatment of parkinsonism containing selective nmda antagonists
HU9601419A HUP9601419A3 (en) 1995-05-26 1996-05-24 Synergetic pharmaceutical compositions for treating parkinson-disease

Publications (1)

Publication Number Publication Date
ATE258067T1 true ATE258067T1 (de) 2004-02-15

Family

ID=89994003

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95918111T ATE258067T1 (de) 1995-05-26 1995-05-26 Kombinationspräparat zur behandlung der parkinsonschen krankheit, das selektive nmda- antagonisten enthält

Country Status (26)

Country Link
US (1) US6258827B1 (de)
EP (1) EP0828513B1 (de)
JP (1) JPH11505828A (de)
CN (1) CN1159325A (de)
AT (1) ATE258067T1 (de)
AU (1) AU696258B2 (de)
BR (1) BR9602485A (de)
CA (1) CA2219911C (de)
CO (1) CO4700422A1 (de)
CZ (1) CZ283979B6 (de)
DE (1) DE69532482T2 (de)
DK (1) DK0828513T3 (de)
ES (1) ES2211904T3 (de)
FI (1) FI974323A0 (de)
HU (1) HUP9601419A3 (de)
IL (1) IL118328A (de)
MX (1) MX9709112A (de)
NO (1) NO962130L (de)
NZ (1) NZ286656A (de)
PL (1) PL314413A1 (de)
PT (1) PT828513E (de)
RU (1) RU2176145C2 (de)
SG (1) SG45479A1 (de)
TR (1) TR199600436A2 (de)
TW (1) TW470740B (de)
WO (1) WO1996037226A2 (de)

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NZ502785A (en) * 1997-10-24 2003-03-28 Warner Lambert Co Use of NR1A/2B site-selective NMDA receptor antagonist compounds for treating disease-related or drug-induced dyskinesias
US6432976B1 (en) 1999-10-29 2002-08-13 Merck & Co., Inc. 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
US6316474B1 (en) 1999-10-29 2001-11-13 Merck & Co., Inc. 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
US6489477B1 (en) 1999-10-29 2002-12-03 Merck & Co., Inc. 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists
US6495561B2 (en) 1999-10-29 2002-12-17 Merck & Co., Inc. 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
CA2386441A1 (en) 1999-10-29 2001-05-03 Merck Sharp & Dohme Limited Method to treat pain utilizing benzimidazole nmda/nr2b antagonists
US6380205B1 (en) 1999-10-29 2002-04-30 Merck & Co., Inc. 2-cyclohexyl quinazoline NMDA/NR2B antagonists
US6291499B1 (en) 1999-10-29 2001-09-18 Merck & Co., Inc. 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
EP1186303A3 (de) * 2000-09-06 2003-12-10 Pfizer Products Inc. Ein Neutrophilhemmender Faktor und ein selektive NMDA-NR2B Rezeptor Antagonisten enthaltende Kombinationspräparate zur Behandlung von Schlaganfällen und traumatischen Gehirnschäden
US7053089B2 (en) 2001-02-23 2006-05-30 Merck & Co., Inc. N-substituted nonaryl-heterocyclic NMDA/NR2B antagonists
WO2002069974A1 (en) * 2001-03-05 2002-09-12 Andrew Holman Administration of sleep restorative agents
JP2005506292A (ja) * 2001-03-08 2005-03-03 エモリー　ユニバーシティ ｐＨに依存するＮＭＤＡレセプターアンタゴニスト
US7259157B2 (en) 2001-04-03 2007-08-21 Merck & Co., Inc. N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B Antagonists
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
DE10142176A1 (de) * 2001-08-29 2003-03-27 Eucro Europe Contract Res Gmbh Verwendung einer Kombination aus ß-adrenergen Agonisten und NDMA-Antagonisten
EP1472248A1 (de) 2002-01-17 2004-11-03 Eli Lilly And Company Acetylcholinrezeptor-modulatoren
US6743921B2 (en) 2002-01-24 2004-06-01 Dsm Catalytica Pharmaceuticals, Inc. Process for the preparation of nonracemic syn-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenyl-piperidin-1-yl)-1-propanol compounds
RU2213565C1 (ru) * 2002-06-24 2003-10-10 Общество с ограниченной ответственностью "Паркинфарм" Способ лечебного воздействия на организм пациента при лечении болезни паркинсона
RU2332218C2 (ru) * 2002-10-08 2008-08-27 Аллерган, Инк. Применение (2-имидазолин-2-иламино) хиноксалинов для лечения деменции и болезни паркинсона
AR044007A1 (es) * 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
US7763588B2 (en) * 2003-06-13 2010-07-27 The Salk Institute For Biological Studies Method for increasing cognitive function and neurogenesis
CA2537765A1 (en) * 2003-09-04 2005-03-17 Board Of Regents, The University Of Texas System Methods and compositions for the prevention and treatment of genitourinary disorders, including pre-term labor and leiomyomas
US20070010584A1 (en) * 2003-09-04 2007-01-11 Peroutka Stephen J Compositions and methods for orthostatic intolerance
EP1588704A1 (de) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamidderivate zur Behandlung des Restless-Leg-Syndroms und der Suchterkrankungen
US20060240043A1 (en) * 2004-10-08 2006-10-26 Meyerson Laurence R Methods and compositions for treating migraine pain
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
RU2281695C1 (ru) * 2004-12-24 2006-08-20 Дмитрий Владимирович Похабов Способ лечения болезни паркинсона
WO2006075004A2 (en) * 2005-01-13 2006-07-20 Neurosearch A/S 3, 8 - substituted 8-aza-bicyclo[3.2.1] octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
EP2243475B1 (de) * 2005-04-06 2016-01-13 Adamas Pharmaceuticals, Inc. Kombination von Memantin und Donepezil zur Behandlung von Erkrankungen des ZNS
US20070118044A1 (en) * 2005-07-18 2007-05-24 Mega Elektroniikka Oy Method and device for identifying; measuring and analyzing abnormal neurological responses
EP1870097A1 (de) * 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamidederivate zur Behandlung von kognitiven Störungen
RU2324492C1 (ru) * 2006-12-04 2008-05-20 Общество с ограниченной ответственностью "Березовый мир" Средство для профилактики и лечения болезни паркинсона
EA201070077A1 (ru) * 2007-06-29 2010-08-30 Эмори Юниверсити Антагонисты nmda-рецепторов с нейропротективным действием
RU2393860C2 (ru) * 2008-05-30 2010-07-10 Государственное образовательное учреждение высшего профессионального образования "Воронежская государственная медицинская академия им. Н.Н. Бурденко Федерального агентства по здравоохранению и социальному развитию" Использование тизанидина в качестве корректора лекарственного паркинсонизма
HUE037974T2 (hu) * 2008-06-06 2018-09-28 Pharma Two B Ltd Gyógyászati kompozíció Parkinson-kór kezelésére
RU2386458C1 (ru) * 2008-09-04 2010-04-20 Государственное Учреждение Научный Центр Неврологии Российской Академии Медицинских Наук Способ лечения болезни паркинсона
US8648198B2 (en) 2011-01-19 2014-02-11 Cold Spring Harbor Laboratory Phenylethanolamine-based NMDA receptor antagonists
JP6042968B2 (ja) * 2012-04-20 2016-12-14 ユセベ ファルマ ソシエテ アノニム パーキンソン病の処置方法
EP4299128A3 (de) 2014-03-13 2024-04-17 Neuroderm Ltd. Dopa-decarboxylase-inhibitor-zusammensetzungen
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease
US12161612B2 (en) 2023-04-14 2024-12-10 Neuroderm, Ltd. Methods and compositions for reducing symptoms of Parkinson's disease

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US5272160A (en) 1989-05-17 1993-12-21 Pfizer Inc 2-piperidino-1-alkanol derivatives as antiischemic agents
HU222726B1 (hu) 1990-02-06 2003-09-29 Pfizer, Inc., Piperidinszármazékok, eljárás elżállításukra és az ezeket tartalmazó gyógyszerkészítmények
US5455250A (en) 1991-04-18 1995-10-03 Pfizer Inc. Prodrug esters of phenolic 2-piperidino-1-alkanols
DE4118740A1 (de) 1991-06-05 1992-12-10 Schering Ag Neue kombinationspraeparate zur behandlung des morbus parkinson
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Also Published As

Publication number Publication date
JPH11505828A (ja) 1999-05-25
HU9601419D0 (en) 1996-07-29
HUP9601419A2 (en) 1997-09-29
HUP9601419A3 (en) 1998-01-28
PL314413A1 (en) 1996-12-09
WO1996037226A2 (en) 1996-11-28
TR199600436A2 (tr) 1996-12-21
CO4700422A1 (es) 1998-12-29
US6258827B1 (en) 2001-07-10
TW470740B (en) 2002-01-01
EP0828513A2 (de) 1998-03-18
PT828513E (pt) 2004-05-31
AU5451996A (en) 1996-12-05
CZ283979B6 (cs) 1998-07-15
ES2211904T3 (es) 2004-07-16
FI974323L (fi) 1997-11-25
DE69532482T2 (de) 2004-11-25
RU2176145C2 (ru) 2001-11-27
SG45479A1 (en) 1998-01-16
DK0828513T3 (da) 2004-04-13
IL118328A (en) 2001-06-14
FI974323A7 (fi) 1997-11-25
EP0828513B1 (de) 2004-01-21
WO1996037226A3 (en) 1996-12-27
CZ152496A3 (cs) 1998-04-15
NO962130L (no) 1996-11-27
IL118328A0 (en) 1996-09-12
FI974323A0 (fi) 1997-11-25
DE69532482D1 (de) 2004-02-26
CN1159325A (zh) 1997-09-17
AU696258B2 (en) 1998-09-03
MX9709112A (es) 1998-02-28
BR9602485A (pt) 1998-04-22
NO962130D0 (no) 1996-05-24
NZ286656A (en) 2001-03-30
CA2219911A1 (en) 1996-11-28
CA2219911C (en) 2004-07-27

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