ATE222489T1 - Thyroxin-analoga ohne bedeutende hormonale wirkung zur behandlung von bösartigen tumoren - Google Patents

Thyroxin-analoga ohne bedeutende hormonale wirkung zur behandlung von bösartigen tumoren

Info

Publication number
ATE222489T1
ATE222489T1 AT98955056T AT98955056T ATE222489T1 AT E222489 T1 ATE222489 T1 AT E222489T1 AT 98955056 T AT98955056 T AT 98955056T AT 98955056 T AT98955056 T AT 98955056T AT E222489 T1 ATE222489 T1 AT E222489T1
Authority
AT
Austria
Prior art keywords
thyroxine
malignant tumors
ketone
treatment
significant hormonal
Prior art date
Application number
AT98955056T
Other languages
English (en)
Inventor
Ernest Kun
Jerome Mendeleyev
Kalman G Buki
Original Assignee
Octamer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octamer Inc filed Critical Octamer Inc
Application granted granted Critical
Publication of ATE222489T1 publication Critical patent/ATE222489T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT98955056T 1997-10-23 1998-10-23 Thyroxin-analoga ohne bedeutende hormonale wirkung zur behandlung von bösartigen tumoren ATE222489T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/956,711 US5922775A (en) 1997-10-23 1997-10-23 Method of treating malignant tumors with ketone thyroxine analogues having no significant hormonal activity
PCT/US1998/022383 WO1999020263A1 (en) 1997-10-23 1998-10-23 Thyroxine analogues having no significant hormonal activity to treat malignant tumors

Publications (1)

Publication Number Publication Date
ATE222489T1 true ATE222489T1 (de) 2002-09-15

Family

ID=25498590

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98955056T ATE222489T1 (de) 1997-10-23 1998-10-23 Thyroxin-analoga ohne bedeutende hormonale wirkung zur behandlung von bösartigen tumoren

Country Status (7)

Country Link
US (1) US5922775A (de)
EP (1) EP1024800B1 (de)
AT (1) ATE222489T1 (de)
AU (1) AU1195499A (de)
DE (1) DE69807349T2 (de)
ES (1) ES2181298T3 (de)
WO (1) WO1999020263A1 (de)

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Publication number Priority date Publication date Assignee Title
US6017958A (en) * 1996-06-04 2000-01-25 Octamer, Inc. Method of treating malignant tumors with thyroxine analogues having no significant hormonal activity
JP2002507567A (ja) * 1998-03-25 2002-03-12 ラージ スケール バイオロジー コーポレイション 血管形成を阻害するための安息香酸誘導体
US6433012B1 (en) * 1998-03-25 2002-08-13 Large Scale Biology Corp. Method for inhibiting inflammatory disease
US6326402B1 (en) 1998-08-12 2001-12-04 Octamer, Inc. Methods for treating viral infections using a compound capable of inhibiting microtubules
US6677473B1 (en) 1999-11-19 2004-01-13 Corvas International Inc Plasminogen activator inhibitor antagonists
US6638977B1 (en) 1999-11-19 2003-10-28 Corvas International, Inc. Plasminogen activator inhibitor antagonists
US6613534B2 (en) 2001-03-20 2003-09-02 Wake Forest University Health Sciences MAP-2 as a determinant of metastatic potential
CN1882327A (zh) * 2003-11-19 2006-12-20 症变治疗公司 含磷的新的拟甲状腺素药
MX2007014502A (es) 2005-05-26 2008-02-07 Metabasis Therapeutics Inc Tiromimeticos para el tratamiento de enfermedades del higado graso.
WO2006128056A2 (en) * 2005-05-26 2006-11-30 Metabasis Therapeutics, Inc. Novel phosphinic acid-containing thyromimetics
ZA200800907B (en) * 2005-07-18 2010-04-28 Bipar Sciences Inc Treatment of cancer
US20080262062A1 (en) * 2006-11-20 2008-10-23 Bipar Sciences, Inc. Method of treating diseases with parp inhibitors
JP2010504079A (ja) * 2006-06-12 2010-02-12 バイパー サイエンシズ,インコーポレイティド Parp阻害剤を用いる疾病の治療方法
WO2008030892A2 (en) * 2006-09-05 2008-03-13 Bipar Sciences, Inc. Drug design for tubulin inhibitors, compositions, and methods of treatment thereof
CN101534836B (zh) * 2006-09-05 2011-09-28 彼帕科学公司 Parp抑制剂在制备治疗肥胖症的药物中的用途
WO2008030887A2 (en) * 2006-09-05 2008-03-13 Bipar Sciences, Inc. Methods for designing parp inhibitors and uses thereof
WO2008030883A2 (en) 2006-09-05 2008-03-13 Bipar Sciences, Inc. Treatment of cancer
CN101903025A (zh) * 2007-10-19 2010-12-01 彼帕科学公司 利用苯并吡喃酮-型parp抑制剂治疗癌症的方法和组合物
US7732491B2 (en) 2007-11-12 2010-06-08 Bipar Sciences, Inc. Treatment of breast cancer with a PARP inhibitor alone or in combination with anti-tumor agents
MX2010008572A (es) * 2008-02-04 2010-11-30 Bipar Sciences Inc Metodos de diagnostico y tratamiento de enfermedades mediadas por poli(adp-ribosa) polimerasa.
WO2018022851A1 (en) 2016-07-28 2018-02-01 Mitobridge, Inc. Methods of treating acute kidney injury
RU2019114863A (ru) 2016-11-02 2020-12-03 Иммуноджен, Инк. Комбинированное лечение конъюгатами антитело-лекарственное средство и ингибиторами parp
JP2020500199A (ja) 2016-11-21 2020-01-09 バイキング・セラピューティクス・インコーポレイテッド グリコーゲン蓄積症の治療方法
MX2019009200A (es) * 2017-02-03 2019-10-21 Univ California Composiciones y métodos para inhibir el reticulón 4.
AU2018280118B2 (en) 2017-06-05 2021-07-15 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis
US11433074B2 (en) 2017-06-22 2022-09-06 Triact Therapeutics, Inc. Methods of treating glioblastoma
EP3687501A4 (de) 2017-09-29 2021-06-23 Triact Therapeutics, Inc. Iniparib-formulierungen und verwendungen davon
WO2020039094A1 (en) * 2018-08-24 2020-02-27 Xeniopro GmbH Phenoxy(hetero)aryl ethers of antiproliferative activity
ES3053674T3 (en) 2018-03-22 2026-01-23 Viking Therapeutics Inc Crystalline forms and methods of producing crystalline forms of a compound
WO2019195658A1 (en) 2018-04-05 2019-10-10 Dana-Farber Cancer Institute, Inc. Sting levels as a biomarker for cancer immunotherapy
WO2020117962A1 (en) 2018-12-05 2020-06-11 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis and inflammation
US20220305048A1 (en) 2019-08-26 2022-09-29 Dana-Farber Cancer Institute, Inc. Use of heparin to promote type 1 interferon signaling

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GB642159A (en) * 1947-10-23 1950-08-30 Glaxo Lab Ltd Improvements in or relating to the preparation of diphenyl ethers
GB643089A (en) * 1947-10-23 1950-09-15 Glaxo Lab Ltd Improvements in or relating to the preparation of 2:6-dihalogeno diphenyl ethers
US4724234A (en) * 1982-09-17 1988-02-09 Therapeutical Systems Corp. Method for producing oncolysis
US4816255A (en) * 1985-07-31 1989-03-28 Ghent William R Treatment of iodine deficiency breast syndrome
GB9211415D0 (en) * 1992-05-29 1992-07-15 Ici Plc Process for the production of purified terephthalic acid
US5736576A (en) * 1996-06-04 1998-04-07 Octamer, Inc. Method of treating malignant tumors with thyroxine analogues having no significant hormonal activity
US6017958A (en) * 1996-06-04 2000-01-25 Octamer, Inc. Method of treating malignant tumors with thyroxine analogues having no significant hormonal activity

Also Published As

Publication number Publication date
EP1024800B1 (de) 2002-08-21
US5922775A (en) 1999-07-13
WO1999020263A1 (en) 1999-04-29
DE69807349T2 (de) 2003-01-02
AU1195499A (en) 1999-05-10
ES2181298T3 (es) 2003-02-16
EP1024800A1 (de) 2000-08-09
DE69807349D1 (de) 2002-09-26

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