ATE411016T1 - Verfahren zur prophylaxis oder behandlung von östrogen-abhängigen krankheiten - Google Patents

Verfahren zur prophylaxis oder behandlung von östrogen-abhängigen krankheiten

Info

Publication number
ATE411016T1
ATE411016T1 AT98940886T AT98940886T ATE411016T1 AT E411016 T1 ATE411016 T1 AT E411016T1 AT 98940886 T AT98940886 T AT 98940886T AT 98940886 T AT98940886 T AT 98940886T AT E411016 T1 ATE411016 T1 AT E411016T1
Authority
AT
Austria
Prior art keywords
estrogen
treatment
prophylaxis
dependent diseases
dependent
Prior art date
Application number
AT98940886T
Other languages
English (en)
Inventor
Donald Mcdonnell
John Norris
Caroline Connor
Ashini Wijayaratne
Original Assignee
Univ Duke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke filed Critical Univ Duke
Application granted granted Critical
Publication of ATE411016T1 publication Critical patent/ATE411016T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98940886T 1997-08-15 1998-08-14 Verfahren zur prophylaxis oder behandlung von östrogen-abhängigen krankheiten ATE411016T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5588197P 1997-08-15 1997-08-15

Publications (1)

Publication Number Publication Date
ATE411016T1 true ATE411016T1 (de) 2008-10-15

Family

ID=22000784

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98940886T ATE411016T1 (de) 1997-08-15 1998-08-14 Verfahren zur prophylaxis oder behandlung von östrogen-abhängigen krankheiten

Country Status (21)

Country Link
US (1) US7307102B2 (de)
EP (1) EP1019057B1 (de)
JP (1) JP2001515038A (de)
KR (1) KR20010022956A (de)
CN (1) CN1275911A (de)
AT (1) ATE411016T1 (de)
AU (1) AU757206B2 (de)
BR (1) BR9811946A (de)
CA (1) CA2301032C (de)
CZ (1) CZ300929B6 (de)
DE (1) DE69840126D1 (de)
EE (1) EE200000077A (de)
ES (1) ES2312189T3 (de)
HU (1) HUP0002852A3 (de)
IL (1) IL134445A0 (de)
NO (1) NO20000752D0 (de)
NZ (1) NZ502738A (de)
PL (1) PL338555A1 (de)
RU (1) RU2214236C2 (de)
UA (1) UA70925C2 (de)
WO (1) WO1999008682A1 (de)

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GB9824207D0 (en) * 1998-11-04 1998-12-30 Zeneca Ltd Neurological disorders
CA2376158C (en) * 1999-07-06 2011-03-15 Endorecherche, Inc. Use of selective estrogen receptor modulators in the manufacture of medicaments for treating and/or suppressing weight gain
CO5271709A1 (es) 2000-01-12 2003-04-30 Pfizer Prod Inc Composiciones y procedimientos para el y tratamiento de afecciones que responden a estrogenos
US6417394B2 (en) * 2000-04-05 2002-07-09 Bristol Myers Squibb Pharma Company Specific salt forms of triphenylethylene derivatives as selective estrogen receptor modulators
US6528681B2 (en) * 2000-04-05 2003-03-04 Bristol-Meyers Squibb Pharma Company Halogenated triphenylethylene derivatives as selective estrogen receptor modulators
US7038595B2 (en) * 2000-07-05 2006-05-02 Seely Andrew J E Method and apparatus for multiple patient parameter variability analysis and display
JP4969016B2 (ja) * 2001-02-15 2012-07-04 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 抗エストロゲン剤とファルネシルプロテイントランスフェラーゼ阻害剤の組み合わせ物
US20020164581A1 (en) * 2001-03-12 2002-11-07 Chawnshang Chang Methods for identifying compounds that do not attenuate the protective effects of estrogen
PL374215A1 (en) 2001-08-11 2005-10-03 Bristol-Myers Squibb Pharma Company Selective estrogen receptor modulators
EP1667955A2 (de) * 2003-07-28 2006-06-14 SmithKline Beecham Corporation Cycloalkylidenverbindungen als modulatoren des östrogenrezeptors
PL1768657T3 (pl) 2004-06-23 2009-01-30 Revision Therapeutics Inc Sposoby i kompozycje do leczenia stanów ocznych za pomocą pochodnych retinylowych
JP2008519054A (ja) 2004-11-04 2008-06-05 シリオン セラピューティクス， インコーポレイテッド レチノール−レチノール結合タンパク質（ｒｂｐ）−トランスチレチン（ｔｔｒ）複合体の形成のモジュレーター
CA2584845C (en) * 2004-12-08 2009-02-17 Sirion Therapeutics, Inc. Methods, assays and compositions for treating retinol-related diseases
US20060264413A1 (en) * 2005-04-18 2006-11-23 Sri International Method and composition for inhibiting cell proliferation and angiogenesis
UA81382C2 (en) * 2005-07-11 2007-12-25 Composition for treating retinol-related diseases by modulation of retinol binding
JP2010540127A (ja) * 2007-10-03 2010-12-24 オタワ ヘルス リサーチ インスティチュート １つ以上の臓器の経時的生理的パラメータ変動を監視するための方法および装置
WO2009151683A2 (en) 2008-03-12 2009-12-17 Link Medicine Corporation Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications
NZ593090A (en) 2008-11-13 2013-06-28 Link Medicine Corp Azaquinolinone derivatives and uses thereof
RS56042B1 (sr) 2010-06-10 2017-09-29 Seragon Pharmaceuticals Inc Modulatori estrogenih receptora i njihove upotrebe
US8853423B2 (en) 2010-06-17 2014-10-07 Seragon Pharmaceuticals, Inc. Indane estrogen receptor modulators and uses thereof
GB2483736B (en) 2010-09-16 2012-08-29 Aragon Pharmaceuticals Inc Estrogen receptor modulators and uses thereof
WO2013090829A1 (en) 2011-12-14 2013-06-20 Aragon Pharmaceuticals, Inc. Estrogen receptor modulators and uses thereof
CN102532073A (zh) * 2011-12-30 2012-07-04 北京赛林泰医药技术有限公司 作为选择性雌激素受体调节剂的乙烯衍生物
CN102584687A (zh) * 2011-12-30 2012-07-18 北京赛林泰医药技术有限公司 作为选择性雌激素受体调节剂的乙烯衍生物
US9499538B2 (en) 2012-03-20 2016-11-22 Seragon Pharmaceuticals, Inc. Estrogen receptor modulators and uses thereof
LT3386500T (lt) * 2015-12-09 2022-12-27 The Board Of Trustees Of The University Of Illinois Selektyvūs estrogenų receptorių slopintojai benzotiofeno pagrindu
US20210094899A1 (en) * 2017-07-28 2021-04-01 Recurium Ip Holdings, Llc Acrylic acid analogs

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Also Published As

Publication number Publication date
HUP0002852A2 (hu) 2001-10-28
HUP0002852A3 (en) 2001-11-28
EP1019057A1 (de) 2000-07-19
PL338555A1 (en) 2000-11-06
AU757206B2 (en) 2003-02-06
NZ502738A (en) 2002-06-28
CA2301032C (en) 2009-01-13
NO20000752L (no) 2000-02-15
CN1275911A (zh) 2000-12-06
NO20000752D0 (no) 2000-02-15
US7307102B2 (en) 2007-12-11
ES2312189T3 (es) 2009-02-16
JP2001515038A (ja) 2001-09-18
DE69840126D1 (de) 2008-11-27
EP1019057A4 (de) 2006-06-14
IL134445A0 (en) 2001-04-30
EE200000077A (et) 2000-12-15
BR9811946A (pt) 2000-08-22
CZ2000531A3 (en) 2001-05-16
UA70925C2 (uk) 2004-11-15
RU2214236C2 (ru) 2003-10-20
EP1019057B1 (de) 2008-10-15
CA2301032A1 (en) 1999-02-25
CZ300929B6 (cs) 2009-09-16
KR20010022956A (ko) 2001-03-26
US20030232795A1 (en) 2003-12-18
AU8906398A (en) 1999-03-08
WO1999008682A1 (en) 1999-02-25

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