ATE222601T1 - Methode zur expression in und isolation von biologisch aktiven molekülen aus urin - Google Patents

Methode zur expression in und isolation von biologisch aktiven molekülen aus urin

Info

Publication number
ATE222601T1
ATE222601T1 AT96916890T AT96916890T ATE222601T1 AT E222601 T1 ATE222601 T1 AT E222601T1 AT 96916890 T AT96916890 T AT 96916890T AT 96916890 T AT96916890 T AT 96916890T AT E222601 T1 ATE222601 T1 AT E222601T1
Authority
AT
Austria
Prior art keywords
expression
urine
isolation
biologically active
active molecules
Prior art date
Application number
AT96916890T
Other languages
English (en)
Inventor
Tung-Tien Sun
Original Assignee
Univ New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York filed Critical Univ New York
Application granted granted Critical
Publication of ATE222601T1 publication Critical patent/ATE222601T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Husbandry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT96916890T 1995-06-05 1996-05-31 Methode zur expression in und isolation von biologisch aktiven molekülen aus urin ATE222601T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/464,961 US5824543A (en) 1995-06-05 1995-06-05 Method for expression and isolation of biologically active molecules in urine using a mouse uroplakin-II promoter
PCT/US1996/008233 WO1996039494A1 (en) 1995-06-05 1996-05-31 Method for expression and isolation of biologically active molecules in urine

Publications (1)

Publication Number Publication Date
ATE222601T1 true ATE222601T1 (de) 2002-09-15

Family

ID=23845974

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96916890T ATE222601T1 (de) 1995-06-05 1996-05-31 Methode zur expression in und isolation von biologisch aktiven molekülen aus urin

Country Status (7)

Country Link
US (2) US5824543A (de)
EP (1) EP0837931B1 (de)
AT (1) ATE222601T1 (de)
AU (1) AU5961596A (de)
CA (1) CA2221453A1 (de)
DE (1) DE69623122T2 (de)
WO (1) WO1996039494A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179611B2 (en) * 1997-02-10 2007-02-20 Bd Lee Laboratories Mono-specific polyclonal antibodies and methods for detecting Clostridium difficile Toxin A
US20020184655A1 (en) * 1997-12-01 2002-12-05 Henryk Lubon Methods for the degradation and detoxification of organic material using urine produced by transgenic animals and related transgenic animals and proteins
US7157615B2 (en) 1998-03-17 2007-01-02 Nexia Biotechnologies, Inc. Production of biofilaments in transgenic animals
JP2002525047A (ja) * 1998-09-16 2002-08-13 ネクシア バイオテクノロジーズ， インコーポレイテッド 尿における組換え蛋白質の産生
US6888047B1 (en) 1998-11-13 2005-05-03 New York University Transgenic animals as urinary bioreactors for the production of polypeptide in the urine, recombinant DNA construct for kidney-specific expression, and method of using same
EP1148779B1 (de) * 1999-01-06 2007-12-12 Merrimack Pharmaceuticals, Inc. Expression von ausgeschiedenem, menschlichem alpha-fetoprotein in transgenen tieren
US6692736B2 (en) * 2000-03-24 2004-02-17 Cell Genesys, Inc. Cell-specific adenovirus vectors comprising an internal ribosome entry site
AU2001245944B2 (en) * 2000-03-24 2007-01-18 Cell Genesys, Inc. Human urothelial cell specific uroplakin transcriptional regulatory sequences, vectors comprising the same, and methods of use thereof
US7048920B2 (en) * 2000-03-24 2006-05-23 Cell Genesys, Inc. Recombinant oncolytic adenovirus for human melanoma
WO2004042062A1 (en) * 2002-11-04 2004-05-21 Cho-A Pharm Co., Ltd. Porcine uroplakin ii promoter and the production method of useful proteins using said promoter
KR100552634B1 (ko) * 2002-11-04 2006-02-20 조아제약주식회사 돼지의 유로플라킨 ⅱ 유전자의 프로모터 및 이를 이용한유용단백질의 생산 방법
US20070061899A1 (en) * 2005-04-13 2007-03-15 The Trustees Of Columbia University In The City Of New York Transgenic mammal with constitutive, tissue-specific cytokine expression and use as a cancer model
TWI682941B (zh) 2013-02-01 2020-01-21 美商再生元醫藥公司 含嵌合恆定區之抗體

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4873191A (en) * 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
WO1994005782A1 (en) * 1992-09-10 1994-03-17 Trustees Of Tufts College In vivo production of transgenic organ by introducing the transgene via lumen

Also Published As

Publication number Publication date
EP0837931A1 (de) 1998-04-29
DE69623122D1 (de) 2002-09-26
US5824543A (en) 1998-10-20
DE69623122T2 (de) 2002-12-12
CA2221453A1 (en) 1996-12-12
EP0837931A4 (de) 1999-06-02
US6001646A (en) 1999-12-14
EP0837931B1 (de) 2002-08-21
AU5961596A (en) 1996-12-24
WO1996039494A1 (en) 1996-12-12

Similar Documents

Publication Publication Date Title
DE69623122D1 (de) Methode zur expression in und isolation von biologisch aktiven molekülen aus urin
DE69432540D1 (de) Verfahren zur Herstellung von Nucleinsäuren aus einer biologischen Probe bei niedrigem pH und unter Verwendung einer Säureprotease
FI880899A0 (fi) Oleellisesti puhdas DNA ja RNA ja menetelmä erytropoietiinin ekspressoimiseksi
DE69031237D1 (de) Verfahren zur Reinigung von Nukleinsäuren
DE69634043D1 (de) Zirkuläres dna molekül mit einem abhängigen replikationsursprung, seine herstellungsverfahren und seine verwendung in der gentherapie
DE69132098D1 (de) Verfahren zur amplifikation von nukleinsäuren
DK257984D0 (da) Fremgangsmaade til fremstilling af en rekombinant baculovirus-udtrykkelsesvektor
DE69838521D1 (de) Methode zur Erhöhung der Konzentration von Nucleinsäuremolekülen
DE69331550D1 (de) Klonierung und expression von biologisch aktiver alpha-galaktosidase a
ATE323510T1 (de) Gentherapeutische verfahren zur bereitstellung von apolipoprotein a-i agonisten sowie deren verwendung zur behandlung dyslipidämischer erkrankungen
PL334530A1 (en) Novel genes specific in respect to n-axecetyl-l-phosphotricin, used to code amino acids deacetylase, their isolation and application
DE69231745D1 (de) Gensequenzen kodierend für Flavonoid-Stoffwechselwegenzyme und deren Verwendung
ATE239036T1 (de) Rekombinantes core-streptavidin
DE69637579D1 (de) Methode zur Amplifizierung von Nukleinsäure und entsprechende Regenzien dafür
ATE217905T1 (de) Zellinien, die einen biologisch aktiven faktor-ix exprimieren
DE69109298D1 (de) Verfahren zur modifizierung von zell-, gewebe- oder wirts-tropismus eines mikroorganismus, so erhaltene rekombinante mikroorganismen sowie deren verwendung in medizin und tiermedizin.
ATE338814T1 (de) Verfahren zur kultivierung von zellen und zur vermehrung von viren
DE69637154D1 (de) Hocheffizientes gewebespezifisches system zur bereitstellung von verbindungen unter verwendung eines streptavidin-protein a fusionsproteins
DE59708441D1 (de) Verfahren zur desintegration von nucleinsäuren und herstellung von qualitätsgesicherten biologischen produkten
DE68926025D1 (de) Methode zur Herstellung von alpha-Amylase hemmenden Substanzen aus Weizen
DE69430975D1 (de) Verfahren zur Herstellung von Proteinen
ATE147437T1 (de) Verfahren zur endoproteolytischen bearbeitung von (vorläufer)proteinen und zur (mikro)biologischen herstellung
DE60038565D1 (de) Verfahren zur herstellung von ubiquinon-10
DE3782560D1 (de) Hefestaemme zur expression fremder gene.
ATE209683T1 (de) Planze resistent gegen mindestens zwei viren und dessen preparation

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties