ATE222908T1 - Spiro(piperidin-4,1'-pyrrolo(3,4-c)pyrrole) - Google Patents

Spiro(piperidin-4,1'-pyrrolo(3,4-c)pyrrole)

Info

Publication number: ATE222908T1
Authority: AT; Austria
Prior art keywords: pyrroles; pyrrolo; spiro; piperidine
Prior art date: 1998-06-12

Application number

AT99110944T

Other languages

English (en)

Inventor

Geo Adam

Frank Dautzenberg

Sabine Kolczewski

Stephan Roever

Juergen Wichmann

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-12

Filing date

1999-06-07

Publication date

2002-09-15

1999-06-07 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2002-09-15 Application granted granted Critical

2002-09-15 Publication of ATE222908T1 publication Critical patent/ATE222908T1/de

Links

KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/20—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Addiction (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

AT99110944T 1998-06-12 1999-06-07 Spiro(piperidin-4,1'-pyrrolo(3,4-c)pyrrole) ATE222908T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98110803		1998-06-12
EP98124119		1998-12-18

Publications (1)

Publication Number	Publication Date
ATE222908T1 true ATE222908T1 (de)	2002-09-15

Family

ID=26149342

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99110944T ATE222908T1 (de)	1998-06-12	1999-06-07	Spiro(piperidin-4,1'-pyrrolo(3,4-c)pyrrole)

Country Status (27)

Country	Link
US (1)	US6075034A (de)
EP (1)	EP0963987B1 (de)
JP (1)	JP3308507B2 (de)
KR (1)	KR100346607B1 (de)
AR (1)	AR018650A1 (de)
AT (1)	ATE222908T1 (de)
AU (1)	AU749995B2 (de)
BR (1)	BR9902245A (de)
CA (1)	CA2274204C (de)
CO (1)	CO5060459A1 (de)
DE (1)	DE69902606T2 (de)
DK (1)	DK0963987T3 (de)
ES (1)	ES2181336T3 (de)
HR (1)	HRP990189A2 (de)
HU (1)	HUP9901909A3 (de)
ID (1)	ID23283A (de)
IL (1)	IL130376A0 (de)
MA (1)	MA26643A1 (de)
NO (1)	NO312069B1 (de)
NZ (1)	NZ336186A (de)
PE (1)	PE20000549A1 (de)
PL (1)	PL333694A1 (de)
PT (1)	PT963987E (de)
SG (1)	SG76623A1 (de)
TR (1)	TR199901304A3 (de)
TW (1)	TW523516B (de)
YU (1)	YU26599A (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2002224038B2 (en)	2000-11-15	2006-03-09	Banyu Pharmaceutical Co., Ltd.	Benzimidazole derivatives
EP1406629A1 (de) *	2001-07-02	2004-04-14	Omeros Corporation	Verfahren zur induzierung von analgesie beinhaltend die verabreichung alternativ eines opiat-rezeptoragonists und eines opiat-rezeptor ähnlichen-1 rezeptoragonists und eine implantierbare infusionspumpe
US20030040479A1 (en) *	2001-07-02	2003-02-27	Omeros Corporation	Rotational intrathecal analgesia method and device
JP2005289816A (ja)	2002-05-14	2005-10-20	Banyu Pharmaceut Co Ltd	ベンズイミダゾール誘導体
AU2004241134A1 (en) *	2003-05-23	2004-12-02	Zealand Pharma A/S	Triaza-spiro compounds as nociceptin analogues and uses thereof
US20050228023A1 (en) *	2003-12-19	2005-10-13	Sri International	Agonist and antagonist ligands of the nociceptin receptor
JP4446978B2 (ja) *	2006-04-28	2010-04-07	トヨタ自動車株式会社	車両用駆動力制御装置
MX2009009355A (es) *	2007-03-01	2009-09-11	Mitsubishi Tanabe Pharma Corp	Compuesto de bencimidazol y uso farmaceutico del mismo.
KR101561666B1 (ko)	2014-08-12	2015-10-20	최인석	골프 퍼팅 교정장치

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5534520A (en) *	1990-04-10	1996-07-09	Fisher; Abraham	Spiro compounds containing five-membered rings
CA2226058C (en) *	1997-01-30	2008-01-29	F. Hoffmann-La Roche Ag	8-substituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives

1999
- 1999-06-07 AT AT99110944T patent/ATE222908T1/de active
- 1999-06-07 ES ES99110944T patent/ES2181336T3/es not_active Expired - Lifetime
- 1999-06-07 DE DE69902606T patent/DE69902606T2/de not_active Expired - Lifetime
- 1999-06-07 EP EP99110944A patent/EP0963987B1/de not_active Expired - Lifetime
- 1999-06-07 PT PT99110944T patent/PT963987E/pt unknown
- 1999-06-07 DK DK99110944T patent/DK0963987T3/da active
- 1999-06-08 PE PE1999000485A patent/PE20000549A1/es not_active Application Discontinuation
- 1999-06-09 SG SG1999002779A patent/SG76623A1/en unknown
- 1999-06-09 CA CA002274204A patent/CA2274204C/en not_active Expired - Fee Related
- 1999-06-09 IL IL13037699A patent/IL130376A0/xx unknown
- 1999-06-09 HU HU9901909A patent/HUP9901909A3/hu unknown
- 1999-06-09 NZ NZ336186A patent/NZ336186A/xx unknown
- 1999-06-09 CO CO99036175A patent/CO5060459A1/es unknown
- 1999-06-10 YU YU26599A patent/YU26599A/sh unknown
- 1999-06-10 MA MA25615A patent/MA26643A1/fr unknown
- 1999-06-10 JP JP16397599A patent/JP3308507B2/ja not_active Expired - Fee Related
- 1999-06-10 TR TR1999/01304A patent/TR199901304A3/tr unknown
- 1999-06-10 KR KR1019990021570A patent/KR100346607B1/ko not_active Expired - Fee Related
- 1999-06-10 AR ARP990102765A patent/AR018650A1/es active IP Right Grant
- 1999-06-11 US US09/330,857 patent/US6075034A/en not_active Expired - Fee Related
- 1999-06-11 PL PL99333694A patent/PL333694A1/xx unknown
- 1999-06-11 HR HR98124119.3A patent/HRP990189A2/hr not_active Application Discontinuation
- 1999-06-11 NO NO19992872A patent/NO312069B1/no unknown
- 1999-06-11 BR BR9902245A patent/BR9902245A/pt not_active Application Discontinuation
- 1999-06-11 AU AU35003/99A patent/AU749995B2/en not_active Ceased
- 1999-06-14 ID IDP990577A patent/ID23283A/id unknown
- 1999-06-21 TW TW088110336A patent/TW523516B/zh active

Also Published As

Publication number	Publication date
AU749995B2 (en)	2002-07-04
EP0963987B1 (de)	2002-08-28
MA26643A1 (fr)	2004-12-20
NO992872L (no)	1999-12-13
HRP990189A2 (en)	2000-02-29
DK0963987T3 (da)	2002-12-30
TR199901304A2 (xx)	2000-01-21
ID23283A (id)	2000-04-05
TR199901304A3 (tr)	2000-01-21
YU26599A (sh)	2002-09-19
CO5060459A1 (es)	2001-07-30
CA2274204C (en)	2009-09-15
AU3500399A (en)	1999-12-23
BR9902245A (pt)	2000-03-21
KR100346607B1 (ko)	2002-08-07
ES2181336T3 (es)	2003-02-16
DE69902606T2 (de)	2003-04-24
KR20000006079A (ko)	2000-01-25
EP0963987A2 (de)	1999-12-15
TW523516B (en)	2003-03-11
EP0963987A3 (de)	2001-01-17
NO992872D0 (no)	1999-06-11
SG76623A1 (en)	2000-11-21
DE69902606D1 (de)	2002-10-02
HUP9901909A2 (hu)	2000-04-28
IL130376A0 (en)	2000-06-01
JP2000053680A (ja)	2000-02-22
NZ336186A (en)	2000-10-27
PL333694A1 (en)	1999-12-20
PE20000549A1 (es)	2000-07-24
AR018650A1 (es)	2001-11-28
CA2274204A1 (en)	1999-12-12
US6075034A (en)	2000-06-13
NO312069B1 (no)	2002-03-11
HU9901909D0 (en)	1999-08-30
PT963987E (pt)	2003-01-31
HUP9901909A3 (en)	2001-11-28
JP3308507B2 (ja)	2002-07-29

Legal Events

Date	Code	Title	Description
2003-01-15	UEP	Publication of translation of european patent specification

Publication	Publication Date	Title
DE59409351D1 (de)	2000-06-21	Pyrrolo[3,4-c]pyrrole
HUP9900575A3 (en)	2001-11-28	Pyrazolopyrimidines as crf receptor antagonists
FI944970A7 (fi)	1995-04-23	Trisyklisiä pyrrolijohdannaisia
ATE202105T1 (de)	2001-06-15	8-substituierte-1,3,8-triazaspiro(4,5)decan-4- onderivate
ZA976492B (en)	1998-01-29	Substituted pyrroles.
DK0837860T3 (da)	2002-05-27	Tricykliske 5,6-dihydro-9H-pyrazolo[3,4-c]-1,2,4-triazolo-[4,3-alfa]pyridiner
DE69902606D1 (de)	2002-10-02	Spiro(piperidin-4,1'-pyrrolo(3,4-c)pyrrole)
DK0970957T3 (da)	2001-12-03	Diaza-spiro[3.5]nonan-derivativer
ZA972829B (en)	1997-10-31	Novel pyrimido [1,2-a]indoles.
ZA993853B (en)	1999-12-13	Spiro[piperidine-4,1'-pyrolo(3,4-C)pyrrole].
ZA974538B (en)	1997-12-01	Novel pyrrole derivatives.
ZA976487B (en)	1998-01-29	Substituted pyrroles.
DE59606457D1 (de)	2001-03-29	Monophasige feste Lösungen mit asymmetrischen Pyrrolo-[4,3-c]-pyrrolen als Wirten
FI943808A7 (fi)	1994-10-24	Triatsolopyrimidiinijohdannaisia angiotensiini II:n reseptoreiden vast avaikuttajina
DE59510186D1 (de)	2002-06-06	Cyaniminogruppen enthaltende Pyrrolo(3,4-c)pyrrole
DE69516467D1 (de)	2000-05-31	Feste Lösungen von Pyrrolo-(3,4-c)-pyrrolen mit Chinacridonchinonen
FI952724A7 (fi)	1995-06-02	Allergian vastaisia triatsolo(pyrrolo, tieno tai furano)-atsepiinijohd annaisia
EP0424315A3 (en)	1992-03-04	Tetracyclic pyrrole lactam derivatives
DE59500031D1 (de)	1996-11-28	Aminoxidgruppen enthaltende Pyrrolo[3,4-c]pyrrole als Photorezeptoren
SI0880523T1 (sl)	2007-04-30	Pirazolopirimidini kot crf receptorski antagonisti
GB9614247D0 (en)	1996-09-04	Pyrrole derivatives