ATE223432T1 - Zyklische peptide mit fungizider wirkung - Google Patents

Zyklische peptide mit fungizider wirkung

Info

Publication number: ATE223432T1
Authority: AT; Austria
Prior art keywords: chem; cyclic peptides; alkyl; fungicidal effect; alkoxy
Prior art date: 1995-05-26

Application number

AT96303603T

Other languages

English (en)

Inventor

Lisa Marie Hammond Lagrandeur

Michael John Rodriguez

Mark James Zweifel

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-26

Filing date

1996-05-21

Publication date

2002-09-15

1996-05-21 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2002-09-15 Application granted granted Critical

2002-09-15 Publication of ATE223432T1 publication Critical patent/ATE223432T1/de

Links

102000001189 Cyclic Peptides Human genes 0.000 title 1
108010069514 Cyclic Peptides Proteins 0.000 title 1
230000000855 fungicidal effect Effects 0.000 title 1
125000004642 (C1-C12) alkoxy group Chemical group 0.000 abstract 1
125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 1
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000002538 fungal effect Effects 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
230000003071 parasitic effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Biophysics (AREA)
Communicable Diseases (AREA)
Biochemistry (AREA)
Oncology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Tropical Medicine & Parasitology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AT96303603T 1995-05-26 1996-05-21 Zyklische peptide mit fungizider wirkung ATE223432T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US45170595A	1995-05-26	1995-05-26

Publications (1)

Publication Number	Publication Date
ATE223432T1 true ATE223432T1 (de)	2002-09-15

Family

ID=23793379

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96303603T ATE223432T1 (de)	1995-05-26	1996-05-21	Zyklische peptide mit fungizider wirkung

Country Status (12)

Country	Link
US (1)	US5629290A (de)
EP (1)	EP0744406B1 (de)
JP (1)	JPH11505846A (de)
AT (1)	ATE223432T1 (de)
AU (1)	AU5799396A (de)
CA (1)	CA2220688A1 (de)
DE (1)	DE69623387T2 (de)
ES (1)	ES2178693T3 (de)
IL (1)	IL118332A0 (de)
PE (1)	PE38297A1 (de)
WO (1)	WO1996037511A1 (de)
ZA (1)	ZA964012B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5965525A (en) *	1992-03-19	1999-10-12	Eli Lilly And Company	Cyclic peptide antifungal agents
US6384013B1 (en)	1992-03-19	2002-05-07	Eli Lilly And Company	Cyclic peptide antifungal agents and process for preparation thereof
US6743777B1 (en) *	1992-03-19	2004-06-01	Eli Lilly And Company	Cyclic peptide antifungal agents and process for preparation thereof
US6323176B1 (en)	1998-02-25	2001-11-27	Eli Lilly And Company	Cyclic peptide antifungal agents
ES2233070T3 (es)	1998-08-20	2005-06-01	ELI LILLY & COMPANY	Sintesis de analogos peptidicos ciclicos modificados en el anillo.
DE69933046T2 (de)	1998-12-09	2007-09-13	Eli Lilly And Co., Indianapolis	Reinigung von echinocandin cyclopeptiden
KR20020003864A (ko) *	1999-03-03	2002-01-15	피터 지. 스트링거	에키노칸딘/탄수화물 착물
WO2000051567A1 (en)	1999-03-03	2000-09-08	Eli Lilly And Company	Processes for making pharmaceutical oral ecb formulations and compositions
AU767956B2 (en)	1999-03-03	2003-11-27	Eli Lilly And Company	Formation and anion-exchange of crystalline echinocandin ammonium salts
EP1582204B1 (de) *	1999-03-03	2013-09-25	Eli Lilly & Company	Echinocandin pharmazeutische Zusammensetzungen enthaltend Mizellen bildende Tenside
US6991800B2 (en) *	2002-06-13	2006-01-31	Vicuron Pharmaceuticals Inc.	Antifungal parenteral products
US7109519B2 (en) *	2003-07-15	2006-09-19	3M Innovative Properties Company	Bis(2-acenyl)acetylene semiconductors
CN116903706B (zh) *	2023-06-13	2024-05-17	深圳市祥根生物有限公司	一种棘白菌素类药物及其制备方法和用途

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4320052A (en) *	1979-12-13	1982-03-16	Eli Lilly And Company	Derivatives of A-30912A nucleus
US4293489A (en) *	1979-12-13	1981-10-06	Eli Lilly And Company	Derivatives of A-30912A nucleus
US4293488A (en) *	1979-12-13	1981-10-06	Eli Lilly And Company	Derivatives of A-30912B nucleus
US5166135A (en) *	1988-09-12	1992-11-24	Merck & Company, Inc.	Method for the control of pneumocystis carinii
DK173802B1 (da) *	1988-09-12	2001-11-05	Merck & Co Inc	Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner
CA2037957A1 (en) *	1990-03-12	1991-09-13	Merck & Co., Inc.	N-acylated cyclohexapeptide compounds
GB2241956A (en) *	1990-03-16	1991-09-18	Merck & Co Inc	N-acylated cyclohexapeptide compounds
US5049546A (en) *	1990-03-19	1991-09-17	Merck & Co., Inc.	Antibiotic agents
IL97347A0 (en) *	1990-03-19	1992-05-25	Merck & Co Inc	Lipopeptide derivatives and antimicrobial compositions containing them
IE910892A1 (en) *	1990-03-19	1991-09-25	Merck & Co Inc	Lipopeptide compounds
US5310726A (en) *	1990-03-19	1994-05-10	Merck & Co., Inc.	Lipopeptide compounds
US5386009A (en) *	1990-03-19	1995-01-31	Merck & Co. Inc.	Lipopeptide derivatives
US5330973A (en) *	1990-03-19	1994-07-19	Merck & Co., Inc.	Lipopeptide derivatives
IE990233A1 (en) *	1990-06-18	2000-11-15	Fujisawa Pharmaceutical Co	New Polypeptide Compound and a Process for Preparation thereof
US5369093A (en) *	1991-03-15	1994-11-29	Merck & Co., Inc.	Lipopeptide derivatives
US5233023A (en) *	1991-07-30	1993-08-03	Merck & Co., Inc.	Process for phosphate ester compounds of certain cyclohexapeptides
NZ247149A (en) *	1992-03-19	1996-10-28	Lilly Co Eli	Cyclic peptide antifungal agents and compositions thereof

1996
- 1996-03-08 US US08/611,611 patent/US5629290A/en not_active Expired - Fee Related
- 1996-05-20 AU AU57993/96A patent/AU5799396A/en not_active Abandoned
- 1996-05-20 JP JP8535784A patent/JPH11505846A/ja not_active Withdrawn
- 1996-05-20 CA CA002220688A patent/CA2220688A1/en not_active Abandoned
- 1996-05-20 WO PCT/US1996/007251 patent/WO1996037511A1/en not_active Ceased
- 1996-05-20 ZA ZA9604012A patent/ZA964012B/xx unknown
- 1996-05-20 IL IL11833296A patent/IL118332A0/xx unknown
- 1996-05-21 AT AT96303603T patent/ATE223432T1/de not_active IP Right Cessation
- 1996-05-21 DE DE69623387T patent/DE69623387T2/de not_active Expired - Fee Related
- 1996-05-21 ES ES96303603T patent/ES2178693T3/es not_active Expired - Lifetime
- 1996-05-21 EP EP96303603A patent/EP0744406B1/de not_active Expired - Lifetime
- 1996-05-22 PE PE1996000371A patent/PE38297A1/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0744406A3 (de)	1998-05-20
JPH11505846A (ja)	1999-05-25
WO1996037511A1 (en)	1996-11-28
EP0744406A2 (de)	1996-11-27
DE69623387D1 (de)	2002-10-10
CA2220688A1 (en)	1996-11-28
ES2178693T3 (es)	2003-01-01
IL118332A0 (en)	1996-09-12
DE69623387T2 (de)	2003-01-09
PE38297A1 (es)	1997-10-09
US5629290A (en)	1997-05-13
AU5799396A (en)	1996-12-11
EP0744406B1 (de)	2002-09-04
ZA964012B (en)	1997-11-20

Legal Events

Date	Code	Title	Description
2003-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE223432T1 (de)	2002-09-15	Zyklische peptide mit fungizider wirkung
EA200300792A1 (ru)	2004-02-26	Хиназолины в качестве ингибиторов ммр-13
FI950309A0 (fi)	1995-01-24	Proliiniamidijohdannaisia
NZ337118A (en)	2000-03-27	3-piperidyl-4-oxoquinazoline derivatives and pharmaceutical compositions comprising the same useful in treating or preventing arteriosclerotic and/or hyper-lipemia disease, pancreatitis, obesity, hypercholesterolemia and hypertriglyceridemia.
ES2148254T3 (es)	2000-10-16	Peptidos antimicrobianos ciclicos y preparacion de los mismos.
EP0976748A4 (de)	2001-08-08	Pyrrolidin-derivate die eine phospholipase-a2-hemmende wirkung haben
BR9608502A (pt)	1999-07-06	Derivado da pirrola e composição medicinal
EA199700307A1 (ru)	1998-04-30	Циклические пептидные антигрибковые агенты
EP0744407A3 (de)	1998-05-20	Zyklische Peptide mit fungizider Wirkung
EP1193256A8 (de)	2002-08-28	Pharmazeutisch aktive Benzolsulfonamidderivate als JNK-Proteininhibitoren
ATE197460T1 (de)	2000-11-11	Zyklische peptide mit antifungischer wirkung
KR940014336A (ko)	1994-07-18	에이즈의 치료에 유용한 에이치아이브이(hiv) 프로테아제 억제제
ATE233786T1 (de)	2003-03-15	Zyklische peptide mit fungizider wirkung
ATE374750T1 (de)	2007-10-15	Serotoninwiederaufnahme-inhibitoren
OA09119A (fr)	1991-10-31	Nouveaux céphèmes et leur préparation.
EA200000374A2 (ru)	2000-12-25	Новые соединения 2,3-метаноаминокислоты, способ их получения и содержащие их фармацевтические композиции
ATE86117T1 (de)	1993-03-15	Zusammensetzung gegen leberkrankheiten.
EA200200682A1 (ru)	2003-02-27	Новые соединения n-бензилпиперазина, способ их получения и фармацевтические композиции, их содержащие
DE69826034D1 (de)	2004-10-07	1,2-dihydro-2-oxochinolin-derivate
DK0904783T3 (da)	2002-09-02	Benzoe(b)thiophen derivater til sænkning af blodpladetælling
WO2000078793A3 (en)	2001-03-22	Antimicrobial agents