ATE223907T1 - Arginnin analoge mit no- syntax inhibierenderwirkung - Google Patents

Arginnin analoge mit no- syntax inhibierenderwirkung

Info

Publication number: ATE223907T1
Authority: AT; Austria
Prior art keywords: pct; carbon atoms; group; alkyl; arginnine
Prior art date: 1995-03-04

Application number

AT96905907T

Other languages

English (en)

Inventor

Colette Broquet

De Lassauniere Pierre Chabrier

Original Assignee

Sod Conseils Rech Applic

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-04

Filing date

1996-03-04

Publication date

2002-09-15

1996-03-04 Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic

2002-09-15 Application granted granted Critical

2002-09-15 Publication of ATE223907T1 publication Critical patent/ATE223907T1/de

Links

230000002401 inhibitory effect Effects 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 3
125000004432 carbon atom Chemical group C* 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
239000011593 sulfur Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/30—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to nitro or nitroso groups
- C07C279/32—N-nitroguanidines
- C07C279/36—Substituted N-nitroguanidines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Immunology (AREA)
Diabetes (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Ophthalmology & Optometry (AREA)
Vascular Medicine (AREA)
Oncology (AREA)
Psychiatry (AREA)
Communicable Diseases (AREA)
Transplantation (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT96905907T 1995-03-04 1996-03-04 Arginnin analoge mit no- syntax inhibierenderwirkung ATE223907T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9504350.1A GB9504350D0 (en)	1995-03-04	1995-03-04	Arginine derivatives
PCT/FR1996/000337 WO1996027593A1 (fr)	1995-03-04	1996-03-04	Analogues de l'arginine ayant une activite en tant qu'inhibiteurs de la no synthase

Publications (1)

Publication Number	Publication Date
ATE223907T1 true ATE223907T1 (de)	2002-09-15

Family

ID=10770627

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96905907T ATE223907T1 (de)	1995-03-04	1996-03-04	Arginnin analoge mit no- syntax inhibierenderwirkung

Country Status (19)

Country	Link
US (1)	US5972940A (de)
EP (1)	EP0813529B1 (de)
JP (1)	JP3496061B2 (de)
KR (1)	KR19980702738A (de)
CN (1)	CN1071328C (de)
AT (1)	ATE223907T1 (de)
AU (1)	AU700871B2 (de)
BG (1)	BG62520B1 (de)
CA (1)	CA2215476C (de)
CZ (1)	CZ290747B6 (de)
DE (1)	DE69623602T2 (de)
ES (1)	ES2182964T3 (de)
GB (1)	GB9504350D0 (de)
HU (1)	HUP9801200A3 (de)
NZ (1)	NZ303235A (de)
PL (1)	PL188916B1 (de)
RU (1)	RU2168493C2 (de)
SK (1)	SK282664B6 (de)
WO (1)	WO1996027593A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9504350D0 (en) *	1995-03-04	1995-04-26	Sod Conseils Rech Applic	Arginine derivatives
FR2808525A1 (fr) *	2000-05-05	2001-11-09	Sod Conseils Rech Applic	Nouveaux derives d'aminoacides et leur application a titre de medicaments
EP1296943A1 (de) *	2000-05-05	2003-04-02	Societe De Conseils De Recherches Et D'applications Scientifiques S.A. (S.C.R.A.S.)	Aminsäure-derivate und ihre verwendung als arzneimittel
FR2824825B1 (fr) *	2001-05-15	2005-05-06	Servier Lab	Nouveaux derives d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2006051314A2 (en) *	2004-11-12	2006-05-18	Ucl Business Plc	Guanidine derivatives as inhibitors of ddah
HU0800031D0 (en) *	2008-01-16	2008-03-28	Biotech Hungary Kutato Es Fejl	Method for stabilization of s-nitrosoglutathione and composition prepared by the same

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL165652C (nl) *	1973-08-13	1981-05-15	Mitsubishi Chem Ind	Werkwijze ter bereiding van een preparaat met anti- trombosewerking en/of diagnosticum voor trombine in bloed op basis van l-argininederivaten, het gevormde preparaat, het gevormde diagnosticum en werkwijze ter bereiding van l-argininederivaten.
US3978045A (en) *	1973-08-13	1976-08-31	Mitsubishi Chemical Industries Ltd.	N2 -dansyl-L-arginine derivatives, and the pharmaceutically acceptable acid addition salts thereof
US4133880A (en) *	1974-11-08	1979-01-09	Mitsubishi Chemical Industries Ltd.	N2 -Substituted-L-arginine derivatives and the pharmaceutically acceptable acid addition salts thereof
CA1106851A (en) *	1975-08-08	1981-08-11	Shosuke Okamoto	N.sup.2-substituted-l-arginine derivatives and the pharmaceutically acceptable acid addition salts thereof
US4585757A (en)	1984-07-27	1986-04-29	Texas Tech University Health Sciences Center	Hypotensive active peptides
US4687840A (en)	1986-02-11	1987-08-18	Texas Tech University Health Sciences Center	Hypotensive active peptides
DE4011505C2 (de) *	1990-04-10	1995-01-12	Sanol Arznei Schwarz Gmbh	Nitratoalkancarbonsäure-Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US5028627A (en) *	1989-09-13	1991-07-02	Cornell Research Foundation, Inc.	Method of using arginine derivatives to inhibit systemic hypotension associated with nitric oxide production or endothelial derived relaxing factor
GB8929076D0 (en) *	1989-12-22	1990-02-28	Scras	Treatment of shock by blocking agents of edrf effect or formation
GB9200114D0 (en) *	1992-01-04	1992-02-26	Scras	Dual inhibitors of no synthase and cyclooxygenase
US5281627A (en) *	1992-05-28	1994-01-25	Cornell Research Foundation, Inc.	Substituted arginines and substituted homoarginines and use thereof
GB9504350D0 (en) *	1995-03-04	1995-04-26	Sod Conseils Rech Applic	Arginine derivatives

1995
- 1995-03-04 GB GBGB9504350.1A patent/GB9504350D0/en active Pending
1996
- 1996-03-04 WO PCT/FR1996/000337 patent/WO1996027593A1/fr not_active Ceased
- 1996-03-04 CN CN96192885A patent/CN1071328C/zh not_active Expired - Fee Related
- 1996-03-04 AT AT96905907T patent/ATE223907T1/de not_active IP Right Cessation
- 1996-03-04 CA CA002215476A patent/CA2215476C/fr not_active Expired - Fee Related
- 1996-03-04 EP EP96905907A patent/EP0813529B1/de not_active Expired - Lifetime
- 1996-03-04 KR KR1019970706145A patent/KR19980702738A/ko not_active Ceased
- 1996-03-04 AU AU49479/96A patent/AU700871B2/en not_active Ceased
- 1996-03-04 US US08/913,455 patent/US5972940A/en not_active Expired - Fee Related
- 1996-03-04 NZ NZ303235A patent/NZ303235A/xx not_active IP Right Cessation
- 1996-03-04 JP JP52665796A patent/JP3496061B2/ja not_active Expired - Fee Related
- 1996-03-04 SK SK1121-97A patent/SK282664B6/sk not_active IP Right Cessation
- 1996-03-04 HU HU9801200A patent/HUP9801200A3/hu unknown
- 1996-03-04 CZ CZ19972687A patent/CZ290747B6/cs not_active IP Right Cessation
- 1996-03-04 ES ES96905907T patent/ES2182964T3/es not_active Expired - Lifetime
- 1996-03-04 PL PL96322069A patent/PL188916B1/pl not_active IP Right Cessation
- 1996-03-04 DE DE69623602T patent/DE69623602T2/de not_active Expired - Lifetime
- 1996-03-04 RU RU97116496/04A patent/RU2168493C2/ru not_active IP Right Cessation
1997
- 1997-10-03 BG BG101942A patent/BG62520B1/bg unknown

Also Published As

Publication number	Publication date
SK282664B6 (sk)	2002-11-06
HUP9801200A2 (hu)	1998-09-28
RU2168493C2 (ru)	2001-06-10
JPH11501043A (ja)	1999-01-26
US5972940A (en)	1999-10-26
DE69623602D1 (de)	2002-10-17
BG62520B1 (bg)	2000-01-31
CN1179774A (zh)	1998-04-22
CZ290747B6 (cs)	2002-10-16
ES2182964T3 (es)	2003-03-16
JP3496061B2 (ja)	2004-02-09
PL188916B1 (pl)	2005-05-31
EP0813529B1 (de)	2002-09-11
GB9504350D0 (en)	1995-04-26
WO1996027593A1 (fr)	1996-09-12
CZ268797A3 (cs)	1998-07-15
NZ303235A (en)	1999-08-30
CN1071328C (zh)	2001-09-19
HUP9801200A3 (en)	1998-12-28
CA2215476A1 (fr)	1996-09-12
DE69623602T2 (de)	2003-07-31
BG101942A (bg)	1999-01-29
HK1013777A1 (en)	1999-09-10
AU4947996A (en)	1996-09-23
AU700871B2 (en)	1999-01-14
KR19980702738A (ko)	1998-08-05
PL322069A1 (en)	1998-01-05
SK112197A3 (en)	1998-01-14
EP0813529A1 (de)	1997-12-29
CA2215476C (fr)	2006-08-15

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