ATE224727T1 - Faktor xiii zur behandlung von hautwunden - Google Patents

Faktor xiii zur behandlung von hautwunden

Info

Publication number: ATE224727T1
Authority: AT; Austria
Prior art keywords: factor xiii; treatment; skin wounds; skin; preparation
Prior art date: 1993-03-30

Application number

AT94908476T

Other languages

English (en)

Inventor

Naoko Kato

Takashi Ogawa

Shuji Kondo

Original Assignee

Hoechst Japan

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-03-30

Filing date

1994-03-02

Publication date

2002-10-15

1994-03-02 Application filed by Hoechst Japan filed Critical Hoechst Japan

2002-10-15 Application granted granted Critical

2002-10-15 Publication of ATE224727T1 publication Critical patent/ATE224727T1/de

Links

206010052428 Wound Diseases 0.000 title 1
208000027418 Wounds and injury Diseases 0.000 title 1
229940012444 factor xiii Drugs 0.000 title 1
108010071289 Factor XIII Proteins 0.000 abstract 2
239000004480 active ingredient Substances 0.000 abstract 2
230000002500 effect on skin Effects 0.000 abstract 2
108010039627 Aprotinin Proteins 0.000 abstract 1
206010072170 Skin wound Diseases 0.000 abstract 1
229960004405 aprotinin Drugs 0.000 abstract 1
ZPNFWUPYTFPOJU-LPYSRVMUSA-N iniprol Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC=4C=CC=CC=4)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=4C=CC=CC=4)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2N(CCC2)C(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N2[C@@H](CCC2)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N2[C@@H](CCC2)C(=O)N3)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H](C(=O)N1)C(C)C)[C@@H](C)O)[C@@H](C)CC)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 ZPNFWUPYTFPOJU-LPYSRVMUSA-N 0.000 abstract 1
238000001990 intravenous administration Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Genetics & Genomics (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Dispersion Chemistry (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Dermatology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Materials Engineering (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT94908476T 1993-03-30 1994-03-02 Faktor xiii zur behandlung von hautwunden ATE224727T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP7139593		1993-03-30
PCT/IB1994/000040 WO1994022470A1 (en)	1993-03-30	1994-03-02	Factor xiii for treatment of skin wounds

Publications (1)

Publication Number	Publication Date
ATE224727T1 true ATE224727T1 (de)	2002-10-15

Family

ID=13459291

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94908476T ATE224727T1 (de)	1993-03-30	1994-03-02	Faktor xiii zur behandlung von hautwunden

Country Status (7)

Country	Link
EP (1)	EP0691850B1 (de)
KR (1)	KR100302935B1 (de)
AT (1)	ATE224727T1 (de)
AU (1)	AU674061B2 (de)
DE (1)	DE69431430T2 (de)
ES (1)	ES2182840T3 (de)
WO (1)	WO1994022470A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994002172A1 (en)	1992-07-24	1994-02-03	Oklahoma Medical Research Foundation	Blockade of protein c activation reduces microvascular surgical blood loss
IL125983A0 (en) *	1998-08-30	1999-04-11	Yeda Res & Dev	Pharmaceutical composition comprising factor xiiia
ES2303561T3 (es)	2001-10-09	2008-08-16	Zymogenetics, Inc.	Metodo para inhibir la formacion de seromas utilizando el factor xiii.
RU2308954C2 (ru)	2002-05-09	2007-10-27	Медиджинез	Фармацевтическая композиция для лечения ран, содержащая плазму или сыворотку крови
JP2004075661A (ja) *	2002-06-18	2004-03-11	Shiseido Co Ltd	表皮基底膜ケアを特徴とする皮膚外用剤、皮膚基底膜構造形成促進剤および人工皮膚の製造方法
EP1566183A1 (de) *	2004-02-20	2005-08-24	ZLB Behring GmbH	Verwendung vom Faktor XIII zur Stimulierung der Durchblutung von ischämischem Gewebe
KR101710471B1 (ko)	2008-04-21	2017-02-27	노보 노르디스크 헬스 케어 악티엔게젤샤프트	건조한 트랜스글루타미나제 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4265233A (en) *	1978-04-12	1981-05-05	Unitika Ltd.	Material for wound healing
AT359653B (de) *	1979-02-15	1980-11-25	Immuno Ag	Verfahren zur herstellung eines gewebekleb- stoffes
ATE121776T1 (de) *	1986-09-19	1995-05-15	Zymogenetics Inc	Expression des biologisch aktiven faktors xiii.
DE3808048A1 (de) *	1988-03-11	1989-09-21	Behringwerke Ag	Verfahren zum affinitaetschromatografischen reinigen von faktor xiii
DE3829524A1 (de) *	1988-08-31	1990-03-01	Behringwerke Ag	Verwendung von transglutaminasen als immunsuppressiva

1994
- 1994-03-02 KR KR1019950704242A patent/KR100302935B1/ko not_active Expired - Fee Related
- 1994-03-02 DE DE69431430T patent/DE69431430T2/de not_active Expired - Lifetime
- 1994-03-02 AU AU61557/94A patent/AU674061B2/en not_active Ceased
- 1994-03-02 ES ES94908476T patent/ES2182840T3/es not_active Expired - Lifetime
- 1994-03-02 AT AT94908476T patent/ATE224727T1/de active
- 1994-03-02 EP EP94908476A patent/EP0691850B1/de not_active Expired - Lifetime
- 1994-03-02 WO PCT/IB1994/000040 patent/WO1994022470A1/en not_active Ceased

Also Published As

Publication number	Publication date
EP0691850A1 (de)	1996-01-17
DE69431430T2 (de)	2003-05-22
KR960701657A (ko)	1996-03-28
EP0691850B1 (de)	2002-09-25
WO1994022470A1 (en)	1994-10-13
ES2182840T3 (es)	2003-03-16
AU6155794A (en)	1994-10-24
DE69431430D1 (de)	2002-10-31
KR100302935B1 (ko)	2001-11-30
AU674061B2 (en)	1996-12-05

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Legal Events

Date	Code	Title	Description
2003-01-15	UEP	Publication of translation of european patent specification