ES2182840T3 - Factor xiii para el tratamiento de heridas de la piel. - Google Patents

Factor xiii para el tratamiento de heridas de la piel.

Info

Publication number
ES2182840T3
ES2182840T3 ES94908476T ES94908476T ES2182840T3 ES 2182840 T3 ES2182840 T3 ES 2182840T3 ES 94908476 T ES94908476 T ES 94908476T ES 94908476 T ES94908476 T ES 94908476T ES 2182840 T3 ES2182840 T3 ES 2182840T3
Authority
ES
Spain
Prior art keywords
factor xiii
treatment
skin wounds
skin
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94908476T
Other languages
English (en)
Inventor
Naoko Kato
Takashi Ogawa
Shuji Kondo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis KK
Original Assignee
Hoechst Japan Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Japan Ltd filed Critical Hoechst Japan Ltd
Application granted granted Critical
Publication of ES2182840T3 publication Critical patent/ES2182840T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

UNA PREPARACION DERMICA PARA EL TRATAMIENTO DE HERIDAS EN LA PIEL QUE CONTIENE COMO INGREDIENTE ACTIVO UN FACTOR XIII DE COAGULACION DE LA SANGRE HUMANA. ESTA PREPARACION PUEDE CONTENER ADEMAS APROTININA. LA PREPARACION DERMICA, CUANDO SE APLICA A LA PIEL DAÑADA, ESPECIALMENTE A LA PIEL QUEMADA O ESCALDADA, PUEDE EJERCER UN SUMINISTRO SUPERIOR DEL INGREDIENTE ACTIVO, EL FACTOR XIII DE COAGULACION DE LA SANGRE HUMANA, AL TEJIDO AFECTADO, EN COMPARACION A LA ADMINISTRACION INTRAVENOSA Y SE PUEDE ADMINISTRAR SIN LA AYUDA DE UN MEDICO.
ES94908476T 1993-03-30 1994-03-02 Factor xiii para el tratamiento de heridas de la piel. Expired - Lifetime ES2182840T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7139593 1993-03-30

Publications (1)

Publication Number Publication Date
ES2182840T3 true ES2182840T3 (es) 2003-03-16

Family

ID=13459291

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94908476T Expired - Lifetime ES2182840T3 (es) 1993-03-30 1994-03-02 Factor xiii para el tratamiento de heridas de la piel.

Country Status (7)

Country Link
EP (1) EP0691850B1 (es)
KR (1) KR100302935B1 (es)
AT (1) ATE224727T1 (es)
AU (1) AU674061B2 (es)
DE (1) DE69431430T2 (es)
ES (1) ES2182840T3 (es)
WO (1) WO1994022470A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0651655A4 (en) 1992-07-24 1996-05-29 Oklahoma Med Res Found REDUCTION OF MICROVASCULAR BLEEDING DURING SURGERY BY BLOCKING PROTEIN C ACTIVATION
IL125983A0 (en) * 1998-08-30 1999-04-11 Yeda Res & Dev Pharmaceutical composition comprising factor xiiia
CA2463530A1 (en) 2001-10-09 2003-05-08 Zymogenetics, Inc. Method for inhibiting the formation of seromas using factor xiii
BR0309890A (pt) 2002-05-09 2005-05-10 Medigenes Composição farmacêutica contendo plasma sanguìneo, ou soro sanguìneo utilizada no tratamento de lesões, bem como seu método e processo de aplicação
JP2004075661A (ja) * 2002-06-18 2004-03-11 Shiseido Co Ltd 表皮基底膜ケアを特徴とする皮膚外用剤、皮膚基底膜構造形成促進剤および人工皮膚の製造方法
EP1566183A1 (en) * 2004-02-20 2005-08-24 ZLB Behring GmbH Use of factor XIII for stimulating the perfusion of ischemic tissue
JP6244079B2 (ja) 2008-04-21 2017-12-06 ノボ ノルディスク ヘルス ケア アーゲー 乾燥トランスグルタミナーゼ組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4265233A (en) * 1978-04-12 1981-05-05 Unitika Ltd. Material for wound healing
AT359653B (de) * 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
DK175919B1 (da) * 1986-09-19 2005-06-27 Univ Washington Ekspression af biologisk aktiv faktor XIII
DE3808048A1 (de) * 1988-03-11 1989-09-21 Behringwerke Ag Verfahren zum affinitaetschromatografischen reinigen von faktor xiii
DE3829524A1 (de) * 1988-08-31 1990-03-01 Behringwerke Ag Verwendung von transglutaminasen als immunsuppressiva

Also Published As

Publication number Publication date
KR100302935B1 (ko) 2001-11-30
EP0691850B1 (en) 2002-09-25
DE69431430D1 (de) 2002-10-31
AU674061B2 (en) 1996-12-05
AU6155794A (en) 1994-10-24
ATE224727T1 (de) 2002-10-15
WO1994022470A1 (en) 1994-10-13
EP0691850A1 (en) 1996-01-17
KR960701657A (ko) 1996-03-28
DE69431430T2 (de) 2003-05-22

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