ATE225334T1 - Sulfonamide und sulfonsäure-ester mit je einem trizyclischen heteroring - Google Patents

Sulfonamide und sulfonsäure-ester mit je einem trizyclischen heteroring

Info

Publication number: ATE225334T1
Authority: AT; Austria
Prior art keywords: ring; tricyclic; lower alkyl; heteroring; sulfonamides
Prior art date: 1993-07-26

Application number

AT94921819T

Other languages

English (en)

Inventor

Hiroshi Yoshino

Norihiro Ueda

Jun Niijima

Toru Haneda

Yoshihiko Kotake

Kentaro Yoshimatsu

Tatsuo Watanabe

Takeshi Nagasu

Naoko Tsukahara

Nozomu Koyanagi

Kyosuke Kitoh

Original Assignee

Eisai Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-07-26

Filing date

1994-07-26

Publication date

2002-10-15

1994-07-26 Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd

2002-10-15 Application granted granted Critical

2002-10-15 Publication of ATE225334T1 publication Critical patent/ATE225334T1/de

Links

229940124530 sulfonamide Drugs 0.000 title abstract 2
150000003456 sulfonamides Chemical class 0.000 title abstract 2
150000003459 sulfonic acid esters Chemical class 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
125000002252 acyl group Chemical group 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000006367 bivalent amino carbonyl group Chemical group [H]N([*:1])C([*:2])=O 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C211/54—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to two or three six-membered aromatic rings
- C07C211/55—Diphenylamines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/56—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in ortho-position
- C07C229/58—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in ortho-position having the nitrogen atom of at least one of the amino groups further bound to a carbon atom of a six-membered aromatic ring, e.g. N-phenyl-anthranilic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/06—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
- C07D221/12—Phenanthridines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/38—[b, e]- or [b, f]-condensed with six-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/38—[b, e]-condensed with two six-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D267/18—[b, e]-condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D267/20—[b, f]-condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/20—[b, e]-condensed with two six-membered rings with hydrogen atoms directly attached to the ring nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D281/14—[b, e]-condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Indole Compounds (AREA)
Pyridine Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

AT94921819T 1993-07-26 1994-07-26 Sulfonamide und sulfonsäure-ester mit je einem trizyclischen heteroring ATE225334T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP20246693		1993-07-26
JP15887094		1994-07-11
PCT/JP1994/001231 WO1995003279A1 (en)	1993-07-26	1994-07-26	Sulfonamide and sulfonic ester derivatives each having tricyclic hetero ring

Publications (1)

Publication Number	Publication Date
ATE225334T1 true ATE225334T1 (de)	2002-10-15

Family

ID=26485859

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94921819T ATE225334T1 (de)	1993-07-26	1994-07-26	Sulfonamide und sulfonsäure-ester mit je einem trizyclischen heteroring

Country Status (8)

Country	Link
US (3)	US5834462A (de)
EP (1)	EP0679641B1 (de)
AT (1)	ATE225334T1 (de)
CA (1)	CA2144854A1 (de)
DE (1)	DE69431470T2 (de)
FI (1)	FI951416A7 (de)
NO (1)	NO951108L (de)
WO (1)	WO1995003279A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
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US6025355A (en) *	1997-05-19	2000-02-15	Cambridge Neuroscience, Inc.	Pharmaceutically active compounds and methods of use
TW460295B (en) *	1998-09-18	2001-10-21	Hedonist Biochemical Technolog	Topical pharmaceutical compositions comprising bismuth subgallate and borneol for wound healing and preventing scarring and granulation
US6521658B1 (en)	1999-05-28	2003-02-18	Abbott Laboratories	Cell proliferation inhibitors
GB0113435D0 (en) *	2001-06-04	2001-07-25	Amersham Pharm Biotech Uk Ltd	Acridone derivatives as labels for fluorescence detection of target materials
PL378116A1 (pl) *	2003-02-27	2006-03-06	Abbott Laboratories	Heterocykliczne inhibitory kinazy
US8957070B2 (en) *	2005-04-20	2015-02-17	Takeda Pharmaceutical Company Limited	Glucokinase activator compounds, methods of activating glucokinase and methods of treating diabetes and obesity
TW200829578A (en)	2006-11-23	2008-07-16	Astrazeneca Ab	Chemical compounds 537
JO2754B1 (en)	2006-12-21	2014-03-15	استرازينكا ايه بي	Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders
ES2547303T3 (es)	2007-01-19	2015-10-05	Ardea Biosciences, Inc.	Inhibidores de MEK
UY31832A (es)	2008-05-20	2010-01-05	Astrazeneca Ab	Derivados de indazol sustituidos con fenilo y benzodioxinilo
EP2323982B1 (de)	2008-08-15	2012-02-29	Georgetown University	Fluoreszente regulatoren der rassf1a-expression und der proliferation humaner krebszellen
TWI410408B (zh) *	2010-03-16	2013-10-01	Purzer Pharmaceutical Co Ltd	苯磺醯胺衍生物及其醫藥組合物
CN102199148A (zh) *	2010-03-25	2011-09-28	瑞安大药厂股份有限公司	苯磺酰胺衍生物及其医药组合物
BR112014003567A2 (pt) *	2011-08-16	2018-08-14	Mt Sinai School Of Medicine	composto, uso de um composto, e, composição farmacêutica
RU2015139700A (ru)	2013-02-19	2017-03-27	Икан Скул Оф Медсин Эт Маунт Синай	Трициклические гетероциклические соединения в качестве противораковых средств
CN106458916A (zh)	2014-03-11	2017-02-22	西奈山伊坎医学院	受限制的三环磺酰胺
CN106458936A (zh)	2014-03-11	2017-02-22	西奈山伊坎医学院	作为抗癌药的三环‑2‑氨基环烷醇衍生的磺酰胺
US9768397B2 (en) *	2014-03-31	2017-09-19	Commonwealth Scientific And Industrial Research Organisation	Phenylenediamine compounds for phosphorescent diazaborole metal complexes
US11053255B2 (en)	2015-06-22	2021-07-06	Georgetown University	Synthesis of mahanine and related compounds
JP6966425B2 (ja)	2015-09-09	2021-11-17	アイカーンスクールオブメディスンアットマウントサイナイIcahn School of Medicine at Mt. Sinai	抗がん剤としての複素環式の限定された三環系スルホンアミド
JP6955485B2 (ja)	2015-09-09	2021-10-27	アイカーンスクールオブメディスンアットマウントサイナイＩｃａｈｎＳｃｈｏｏｌｏｆＭｅｄｉｃｉｎｅａｔＭｔ．Ｓｉｎａｉ	抗がん剤としての複素環式の限定された三環系スルホンアミド
US11369618B2 (en) *	2016-06-17	2022-06-28	The Trustees Of The University Of Pennsylvania	Compounds, compositions and methods for prevention and/or treatment of cancer
CN117209426B (zh) *	2023-09-11	2026-05-19	广西中医药大学	类两面针碱-磺胺衍生物及其制备方法和应用

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DE2361492A1 (de) *	1973-12-10	1975-06-12	Thiemann Chem Pharm Fab	1-amino-xanthone und -acridone und solche verbindungen enthaltende arzneimittel
EP0215200B1 (de) *	1985-06-24	1992-09-09	Merck & Co. Inc.	Verwendung von sulfanilamido Quinoxalinen zur Behandlung von neoplastischen Krankheiten
ATE167473T1 (de) *	1990-08-20	1998-07-15	Eisai Co Ltd	Sulfonamid-derivate
JP2790926B2 (ja) *	1990-08-20	1998-08-27	エーザイ株式会社	スルホンアミド誘導体

1994
- 1994-07-26 DE DE69431470T patent/DE69431470T2/de not_active Expired - Lifetime
- 1994-07-26 EP EP94921819A patent/EP0679641B1/de not_active Expired - Lifetime
- 1994-07-26 WO PCT/JP1994/001231 patent/WO1995003279A1/ja not_active Ceased
- 1994-07-26 US US08/397,254 patent/US5834462A/en not_active Expired - Lifetime
- 1994-07-26 CA CA002144854A patent/CA2144854A1/en not_active Abandoned
- 1994-07-26 AT AT94921819T patent/ATE225334T1/de not_active IP Right Cessation
1995
- 1995-03-23 NO NO951108A patent/NO951108L/no unknown
- 1995-03-24 FI FI951416A patent/FI951416A7/fi not_active Application Discontinuation
1996
- 1996-12-05 US US08/760,738 patent/US5854274A/en not_active Expired - Lifetime
1997
- 1997-06-11 US US08/873,033 patent/US5846969A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0679641B1 (de)	2002-10-02
US5846969A (en)	1998-12-08
NO951108D0 (no)	1995-03-23
DE69431470T2 (de)	2003-08-14
FI951416A0 (fi)	1995-03-24
FI951416A7 (fi)	1995-05-17
EP0679641A4 (de)	1996-03-20
US5854274A (en)	1998-12-29
DE69431470D1 (de)	2002-11-07
WO1995003279A1 (en)	1995-02-02
CA2144854A1 (en)	1995-02-02
NO951108L (no)	1995-05-23
EP0679641A1 (de)	1995-11-02
US5834462A (en)	1998-11-10

Legal Events

Date	Code	Title	Description
2003-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69431470D1 (de)	2002-11-07	Sulfonamide und sulfonsäure-ester mit je einem trizyclischen heteroring
NO951813L (no)	1995-05-09	Bicyklisk heterocyklisk sulfonamid og sulfonester-derivater
NO950009D0 (no)	1995-01-02	Heterocykliske forbindelser som farmasöytika
ATE205515T1 (de)	2001-09-15	Versteifte trimethin-cyaninfarbstoffe
ES2063929T3 (es)	1995-01-16	Derivados de acido oxi-fenoxiacetico heterociclicos y su uso como herbicidas.
FI103338B1 (fi)	1999-06-15	Pestisidinä käytettävät N-fenyylipyratsolijohdannaiset
ATE88714T1 (de)	1993-05-15	2'-desoxy-5-fluoruridinderivate.
ATE227322T1 (de)	2002-11-15	Versteifte monomethin-cyaninfarbstoffe
ATE147730T1 (de)	1997-02-15	Neue zwischenverbindungen zur herstellung von guanidinderivaten, ihre herstellung und verwendung
DK0604368T3 (de)	1997-02-24
SE8700328D0 (sv)	1987-01-28	Amine derivatives, processes for their production and their use
BR9103951A (pt)	1992-05-26	Composicao anti-incrustante aquatica
ATE154351T1 (de)	1997-06-15	2,3-diphenyl-5-pyrrolyl-furan derivate, verfahren und zwischenprodukte für ihre herstellung und ihre verwendung als entzündungshemmende, antiallergische und blutplättchenaggregationshemmende mittel
DE69131835D1 (de)	2000-01-13	Methotrexatderivate mit antirheumatischer aktivität
DK0601191T3 (da)	1999-04-26	Hidtil ukendt tetracyklisk forbindelse
DE68906826D1 (de)	1993-07-08	Phenothiazinderivate, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.
PT87050A (pt)	1988-04-01	Process for preparing indane sulfonamides antiarrhythmic agents
ATE69217T1 (de)	1991-11-15	Dialkoxyketone und ein verfahren zu ihrer herstellung.
DE3765206D1 (de)	1990-10-31	Substituierte 2-aminotetraline.
TW275084B (de)	1996-05-01
EP0529100A4 (en)	1993-05-26	Indolinospirobenzopyran derivative
FI821570L (fi)	1982-05-05	Nya aminoalkylfuranderivat och foerfarande foer deras framstaellning
GB1070117A (en)	1967-05-24	Anthraquinone dyes and their production
MX9703112A (es)	1997-07-31	Nitro-benzamidas utiles como agentes antiarritmicos.