ATE225666T1 - Verwendung von igf-1 und igfbp-3 zur herstellung eines arzneimittels zur behandlung von einer nierenerkrankung - Google Patents
Verwendung von igf-1 und igfbp-3 zur herstellung eines arzneimittels zur behandlung von einer nierenerkrankungInfo
- Publication number
- ATE225666T1 ATE225666T1 AT95901918T AT95901918T ATE225666T1 AT E225666 T1 ATE225666 T1 AT E225666T1 AT 95901918 T AT95901918 T AT 95901918T AT 95901918 T AT95901918 T AT 95901918T AT E225666 T1 ATE225666 T1 AT E225666T1
- Authority
- AT
- Austria
- Prior art keywords
- igfbp
- igf
- acute
- producing
- kidney disease
- Prior art date
Links
- 102000004374 Insulin-like growth factor binding protein 3 Human genes 0.000 title abstract 2
- 108090000965 Insulin-like growth factor binding protein 3 Proteins 0.000 title abstract 2
- 208000017169 kidney disease Diseases 0.000 title abstract 2
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 title 1
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 230000001154 acute effect Effects 0.000 abstract 2
- 208000009304 Acute Kidney Injury Diseases 0.000 abstract 1
- 208000003918 Acute Kidney Tubular Necrosis Diseases 0.000 abstract 1
- 206010018364 Glomerulonephritis Diseases 0.000 abstract 1
- 208000033626 Renal failure acute Diseases 0.000 abstract 1
- 206010038540 Renal tubular necrosis Diseases 0.000 abstract 1
- 201000011040 acute kidney failure Diseases 0.000 abstract 1
- 208000012998 acute renal failure Diseases 0.000 abstract 1
- 230000001363 autoimmune Effects 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 208000020832 chronic kidney disease Diseases 0.000 abstract 1
- 208000022831 chronic renal failure syndrome Diseases 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 206010061989 glomerulosclerosis Diseases 0.000 abstract 1
- 201000006334 interstitial nephritis Diseases 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 230000003907 kidney function Effects 0.000 abstract 1
- 230000008085 renal dysfunction Effects 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Marine Sciences & Fisheries (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15286293A | 1993-11-15 | 1993-11-15 | |
| PCT/US1994/013178 WO1995013824A1 (en) | 1993-11-15 | 1994-11-15 | Method of treating renal disease by administering igf-i and igfbp-3 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE225666T1 true ATE225666T1 (de) | 2002-10-15 |
Family
ID=22544774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95901918T ATE225666T1 (de) | 1993-11-15 | 1994-11-15 | Verwendung von igf-1 und igfbp-3 zur herstellung eines arzneimittels zur behandlung von einer nierenerkrankung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5723441A (de) |
| EP (1) | EP0732933B1 (de) |
| JP (1) | JPH09509141A (de) |
| AT (1) | ATE225666T1 (de) |
| AU (1) | AU690941B2 (de) |
| CA (1) | CA2176709A1 (de) |
| DE (1) | DE69431527T2 (de) |
| WO (1) | WO1995013824A1 (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5728676A (en) * | 1994-09-08 | 1998-03-17 | Ciba-Geigy Corporation | Use of insulin-like growth factors I and II for inhibition of inflammatory response |
| US5741776A (en) * | 1995-05-22 | 1998-04-21 | Genentech, Inc. | Method of administration of IGF-I |
| US6498142B1 (en) * | 1996-05-06 | 2002-12-24 | Curis, Inc. | Morphogen treatment for chronic renal failure |
| WO1998011913A1 (en) * | 1996-09-16 | 1998-03-26 | Dalhousie University | Use of igf-i for the treatment of polycystic kidney disease and related indications |
| US6514937B1 (en) | 1997-02-25 | 2003-02-04 | Celtrix Pharmaceuticals, Inc. | Method of treating psychological and metabolic disorders using IGF or IGF/IGFBP-3 |
| US6015786A (en) * | 1997-02-25 | 2000-01-18 | Celtrix Pharmaceuticals, Inc. | Method for increasing sex steroid levels using IGF or IGF/IGFBP-3 |
| US6025368A (en) * | 1997-02-25 | 2000-02-15 | Celtrix Pharmaceuticals, Inc. | Method for treating the symptoms of chronic stress-related disorders using IGF |
| CA2289123A1 (en) * | 1997-05-05 | 1998-11-12 | Creative Biomolecules, Inc. | Therapies for acute renal failure |
| US6417330B1 (en) | 1998-06-01 | 2002-07-09 | Celtrix Pharmaceuticals, Inc. | Insulin-like growth factor binding protein variants |
| US6436897B2 (en) * | 1998-06-01 | 2002-08-20 | Celtrix Pharmaceuticals, Inc. | Pharmaceutical formulations for IGF/IGFBP |
| US7288516B1 (en) | 1999-09-20 | 2007-10-30 | Celtrix Pharmaceuticals, Inc. | Null IGF for the treatment of cancer |
| US6040292A (en) * | 1999-06-04 | 2000-03-21 | Celtrix Pharmaceuticals, Inc. | Methods for treating diabetes |
| BR0113626A (pt) | 2000-08-30 | 2003-06-17 | Pfizer Prod Inc | Formulações de liberação sustentada para secretores de hormÈnio do crescimento |
| CA2422625A1 (en) * | 2000-09-19 | 2002-03-28 | Bioexpertise, Llc | Method for use of igf-binding protein for selective sensitization of target cells in vivo |
| PT1384075E (pt) * | 2001-03-28 | 2010-03-23 | Heska Corp | Métodos de detecção de doença renal inicial em animais |
| US6861406B2 (en) * | 2001-09-18 | 2005-03-01 | Bioexpertise, Llc | IGF-binding protein-derived peptide |
| US6887851B2 (en) * | 2001-09-18 | 2005-05-03 | Bioexpertise, Llc | IGF-binding protein-derived peptide |
| US6914049B2 (en) | 2001-09-18 | 2005-07-05 | Bioexpertise, Llc | IGF-binding protein-derived peptide or small molecule |
| US20040152170A1 (en) * | 2001-12-14 | 2004-08-05 | Lee Chichang | Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media |
| US20030166147A1 (en) * | 2001-12-14 | 2003-09-04 | Lee Chichang | Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media |
| WO2003052064A2 (en) * | 2001-12-14 | 2003-06-26 | Centocor Inc. | Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media |
| US20050272649A1 (en) * | 2002-08-28 | 2005-12-08 | Hruska Keith A | Conjoint administration of morphogens and ACE inhibitors in treatment of chronic renal failure |
| US20050049210A1 (en) * | 2003-08-27 | 2005-03-03 | Idexx Laboratories, Inc. | Methods for the controlled delivery of pharmacologically active compounds |
| US20100028302A1 (en) * | 2004-09-27 | 2010-02-04 | Ludwig-Maximilians- Universität München | Use of IGFBP-2 in Senescence Diseases and for the Maintenance of Organ Functions |
| US20090176864A1 (en) * | 2004-11-24 | 2009-07-09 | Hill's Pet Nutrition, Inc. | Methods For Improving Hepatic and Immune Function In An Animal |
| EP1817058B1 (de) * | 2004-11-24 | 2015-09-02 | Hill's Pet Nutrition, Inc. | Zusammensetzung zur verwendung der verbesserung der beseitigung von xenobiotischen substanzen aus der leber bei einem tier |
| WO2006069029A1 (en) * | 2004-12-24 | 2006-06-29 | Insmed, Inc. | Purified rhigf-i/rhigfbp-3 complexes and their method of manufacture |
| US8647660B2 (en) | 2004-12-29 | 2014-02-11 | Hill's Pet Nutrition, Inc. | Combination of limited nutrients and enhanced dietary antioxidants to impart improved kidney health |
| US8252742B2 (en) * | 2004-12-30 | 2012-08-28 | Hill's Pet Nutrition, Inc. | Methods for enhancing the quality of life of a senior animal |
| AU2005322887B2 (en) * | 2004-12-30 | 2010-03-11 | Hill's Pet Nutrition, Inc. | Methods for enhancing the quality of life of a senior animal |
| AU2006236345B2 (en) * | 2005-04-19 | 2011-03-31 | Hill's Pet Nutrition, Inc. | Methods and compositions for the prevention and treatment of kidney disease |
| AU2006242463A1 (en) * | 2005-04-29 | 2006-11-09 | Hill's Pet Nutrition, Inc. | Methods for prolonging feline life |
| CA2608670C (en) * | 2005-05-20 | 2019-03-05 | Hill's Pet Nutrition, Inc. | Methods for promoting health or wellness in adult animals |
| EP1896070A4 (de) * | 2005-06-29 | 2009-04-29 | Hills Pet Nutrition Inc | Verfahren und zusammensetzungen für die vorbeugung und behandlung von nierenerkrankungen |
| CN101287460B (zh) | 2005-08-17 | 2012-04-25 | 希尔氏宠物营养品公司 | 预防和治疗肾病的组合物 |
| EP1952823A1 (de) * | 2007-01-30 | 2008-08-06 | AM-Pharma B.V. | Verwendung von alkalischer Phosphatase bei der Behandlung eingeschränkter Nierenfunktion |
| ES2810813T3 (es) | 2014-01-24 | 2021-03-09 | Am Pharma Bv | Procesamiento para recuperación y purificación de una fosfatasa alcalina |
| CA2937328C (en) | 2014-01-24 | 2022-09-27 | Am-Pharma B.V. | Chimeric alkaline phosphatase-like proteins |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| IL71991A (en) * | 1983-06-06 | 1994-05-30 | Genentech Inc | Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes |
| EP0327503B1 (de) * | 1988-02-05 | 1993-03-10 | Ciba-Geigy Ag | Verwendung von IGF I zur Herstellung eines Präparates für die Behandlung von Nierenkrankheiten |
| US5273961A (en) * | 1992-09-22 | 1993-12-28 | Genentech, Inc. | Method of prophylaxis of acute renal failure |
-
1994
- 1994-11-15 CA CA002176709A patent/CA2176709A1/en not_active Abandoned
- 1994-11-15 DE DE69431527T patent/DE69431527T2/de not_active Expired - Fee Related
- 1994-11-15 EP EP95901918A patent/EP0732933B1/de not_active Expired - Lifetime
- 1994-11-15 AU AU10982/95A patent/AU690941B2/en not_active Ceased
- 1994-11-15 JP JP7514568A patent/JPH09509141A/ja active Pending
- 1994-11-15 AT AT95901918T patent/ATE225666T1/de not_active IP Right Cessation
- 1994-11-15 WO PCT/US1994/013178 patent/WO1995013824A1/en not_active Ceased
-
1995
- 1995-08-31 US US08/521,907 patent/US5723441A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69431527D1 (de) | 2002-11-14 |
| EP0732933B1 (de) | 2002-10-09 |
| EP0732933A1 (de) | 1996-09-25 |
| DE69431527T2 (de) | 2003-06-26 |
| JPH09509141A (ja) | 1997-09-16 |
| CA2176709A1 (en) | 1995-05-26 |
| EP0732933A4 (de) | 1996-11-06 |
| AU1098295A (en) | 1995-06-06 |
| US5723441A (en) | 1998-03-03 |
| WO1995013824A1 (en) | 1995-05-26 |
| AU690941B2 (en) | 1998-05-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |