ATE225808T1 - Ligand fähig zur bindung an der adenosinedeaminase-bindungsstelle von cd26 - Google Patents

Ligand fähig zur bindung an der adenosinedeaminase-bindungsstelle von cd26

Info

Publication number
ATE225808T1
ATE225808T1 AT95900671T AT95900671T ATE225808T1 AT E225808 T1 ATE225808 T1 AT E225808T1 AT 95900671 T AT95900671 T AT 95900671T AT 95900671 T AT95900671 T AT 95900671T AT E225808 T1 ATE225808 T1 AT E225808T1
Authority
AT
Austria
Prior art keywords
binding
functional derivative
ligand
adenosinedeaminase
immuno
Prior art date
Application number
AT95900671T
Other languages
English (en)
Inventor
Meester Ingrid De
Ham Guido Van
Luc Kestens
Greta Vanhoof
Peggy Verhelst
Filip Goossens
Dirk Hendriks
Marianne Borloo
Achiel Haemers
Eugene Bosmans
Simon Scharpe
Original Assignee
Eurogenetics Nv
Universitaire Instelling Antwe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurogenetics Nv, Universitaire Instelling Antwe filed Critical Eurogenetics Nv
Application granted granted Critical
Publication of ATE225808T1 publication Critical patent/ATE225808T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
AT95900671T 1993-11-04 1994-11-04 Ligand fähig zur bindung an der adenosinedeaminase-bindungsstelle von cd26 ATE225808T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP93203093 1993-11-04
NL9400309A NL9400309A (nl) 1993-11-04 1994-02-28 Ligande die in staat is te binden aan de adenosine deaminase bindingsplaats van CD26.
PCT/EP1994/003632 WO1995012618A1 (en) 1993-11-04 1994-11-04 A ligand capable of binding to the adenosine deaminase binding-site of cd26

Publications (1)

Publication Number Publication Date
ATE225808T1 true ATE225808T1 (de) 2002-10-15

Family

ID=8214159

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95900671T ATE225808T1 (de) 1993-11-04 1994-11-04 Ligand fähig zur bindung an der adenosinedeaminase-bindungsstelle von cd26

Country Status (9)

Country Link
EP (2) EP1179542A1 (de)
AT (1) ATE225808T1 (de)
AU (1) AU8140494A (de)
DE (1) DE69431526T2 (de)
DK (1) DK0726915T3 (de)
ES (1) ES2180619T3 (de)
NL (1) NL9400309A (de)
PT (1) PT726915E (de)
WO (1) WO1995012618A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6825169B1 (en) 1991-10-22 2004-11-30 Trustees Of Tufts College Inhibitors of dipeptidyl-aminopeptidase type IV
WO1997000083A1 (en) * 1995-06-16 1997-01-03 Enzon, Inc. Method of treating cd4+ t cell lymphopenia in immuno-compromised patients
US5728560A (en) * 1996-06-14 1998-03-17 Enzon, Inc. Method of treating CD4+ T cell lymphopenia in immuno-compromised patients
US5965532A (en) * 1996-06-28 1999-10-12 Trustees Of Tufts College Multivalent compounds for crosslinking receptors and uses thereof
US6040145A (en) 1997-05-07 2000-03-21 Tufts University Potentiation of the immune response
US6100234A (en) 1997-05-07 2000-08-08 Tufts University Treatment of HIV
ATE357509T1 (de) 1997-09-29 2007-04-15 Point Therapeutics Inc Stimulierung von hämatopoietischen zellen im vitro
IL139247A0 (en) 1998-05-04 2001-11-25 Point Therapeutics Inc Hematopoietic stimulation
JP2002517401A (ja) 1998-06-05 2002-06-18 ポイント セラピューティクス， インコーポレイテッド 環状ボロプロリン化合物
US6979697B1 (en) 1998-08-21 2005-12-27 Point Therapeutics, Inc. Regulation of substrate activity
US6890904B1 (en) 1999-05-25 2005-05-10 Point Therapeutics, Inc. Anti-tumor agents
EP2767549A1 (de) * 2013-02-19 2014-08-20 Adienne S.A. Anti-CD26-Antikörper und Verwendungen davon
US11242399B2 (en) 2013-02-19 2022-02-08 Adienne S.A. Anti-CD26 antibodies
TWI677505B (zh) * 2014-08-18 2019-11-21 瑞士商艾迪安納股份有限公司 抗ｃｄ２６抗體及其用途

Also Published As

Publication number Publication date
DE69431526T2 (de) 2003-07-10
ES2180619T3 (es) 2003-02-16
AU8140494A (en) 1995-05-23
DK0726915T3 (da) 2003-02-17
EP0726915A1 (de) 1996-08-21
WO1995012618A1 (en) 1995-05-11
NL9400309A (nl) 1995-06-01
PT726915E (pt) 2003-02-28
DE69431526D1 (de) 2002-11-14
EP0726915B1 (de) 2002-10-09
EP1179542A1 (de) 2002-02-13

Similar Documents

Publication Publication Date Title
ATE225808T1 (de) Ligand fähig zur bindung an der adenosinedeaminase-bindungsstelle von cd26
DE3586479D1 (de) Markierte antikoerperfragmente.
GR3026658T3 (en) Hydrazino-type radionuclide chelators having an n 3?s configuration
DE3766157D1 (de) Kupplungsmittel zum radiomarkieren von proteinen.
ES2067604T3 (es) Anticuerpos frente a proteina que se une a tnf i y a sus fragmentos f(ab).
ATE128974T1 (de) Neue kondensierte heterocyclische verbindungen und ihre verwendung für heilmittel.
IT1244876B (it) Nerofumo e composizioni elastomeriche che lo incorporano.
DE69433285D1 (de) Hepatitis-b-virusmutanten, und verbindungen und verfahren für ihre bestimmung
CA2093928A1 (en) Monoclonal antibodies for detection and treatment of cancer
GR1000118B (el) Συνθεσις 1,2-διοξετανων & ενδιαμεσαι ουσιαι δι αυτην.
ES2141086T3 (es) Anticuerpos contra los ligando-analogos y su uso en los dosificados ligando-receptores.
SE9003571D0 (sv) Ljuddaempare foer motorfordon
IL93207A0 (en) A monoclonal antibody which binds to factor betaxiia and shows no substantial binding to factor xii
EE03783B1 (et) Farmatseutiline kompositsioon epitelioomide raviks ja antikeha või antikeha molekuli kasutamine
ATE191568T1 (de) Spezifische bindungssubstanzen für antikörper und deren verwendung für immunoassays oder vakzine
FI963638L (fi) Menetelmiä HIV-1-injektion diagnosoimiseksi ja hoitamiseksi
YU46858B (sh) Postupak za dobijanje imunoglobulinskih konjugata
TR199600117A2 (tr) Ikame edilen benzolsülfonilüre ve tiyoüre, bu maddelerin elde edilmesi ve eczanecilikle ilgili maddelerin bu bilesimler ve bu bilesimleri iceren iyilestirici maddelere dayanarak kullanilmasi ile ilgili usul.
DE69022795D1 (de) Nachweis eines Antikörpers und dessen Immunglobulin-Klasse.
DE69013372D1 (de) Ori-gehemmte und niederschlagsbeständige Motorkraftstoffzusammensetzung.
NO913293L (no) Komponenter til motorer og kjoeretoey.
OA08559A (fr) Anticorps monoclonaux à réactivité et à protectivité croisées vis-à-vis des sérotypes de P. Aeruginosa.
DE3852914D1 (de) Monoklonale Antikörper und Diagnoseverfahren für Phytophthora-Infektionen.
FI956041A0 (fi) Kompositiot ja diagnostiset menetelmät, joissa käytetään monoklonaalisia vasta-aineita CD44V6 vastaan
FI875475A7 (fi) Hiiren hybridoma Lym-1 ja sillä tuotettu diagnostinen vasta-aine.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0726915

Country of ref document: EP

REN Ceased due to non-payment of the annual fee