ATE225848T1 - Immortalisierte menschliche fötale osteoblastenzellen - Google Patents

Immortalisierte menschliche fötale osteoblastenzellen

Info

Publication number
ATE225848T1
ATE225848T1 AT94923403T AT94923403T ATE225848T1 AT E225848 T1 ATE225848 T1 AT E225848T1 AT 94923403 T AT94923403 T AT 94923403T AT 94923403 T AT94923403 T AT 94923403T AT E225848 T1 ATE225848 T1 AT E225848T1
Authority
AT
Austria
Prior art keywords
human fetal
immortalized human
osteoblast cells
fetal osteoblast
cells
Prior art date
Application number
AT94923403T
Other languages
English (en)
Inventor
Steven A Harris
Thomas C Spelsberg
Original Assignee
Mayo Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/089,848 external-priority patent/US5691175A/en
Application filed by Mayo Foundation filed Critical Mayo Foundation
Application granted granted Critical
Publication of ATE225848T1 publication Critical patent/ATE225848T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/22011—Polyomaviridae, e.g. polyoma, SV40, JC
    • C12N2710/22022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
AT94923403T 1993-07-12 1994-07-12 Immortalisierte menschliche fötale osteoblastenzellen ATE225848T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/089,848 US5691175A (en) 1993-07-12 1993-07-12 Immortalized human fetal osteoblastic cells
US08/273,351 US5681701A (en) 1993-07-12 1994-07-11 Immortalized human fetal osteoblastic cells
PCT/US1994/007723 WO1995002687A1 (en) 1993-07-12 1994-07-12 Immortalized human fetal osteoblastic cells

Publications (1)

Publication Number Publication Date
ATE225848T1 true ATE225848T1 (de) 2002-10-15

Family

ID=26780994

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94923403T ATE225848T1 (de) 1993-07-12 1994-07-12 Immortalisierte menschliche fötale osteoblastenzellen

Country Status (7)

Country Link
US (2) US5681701A (de)
EP (1) EP0743982B1 (de)
AT (1) ATE225848T1 (de)
AU (1) AU7327694A (de)
CA (1) CA2166973C (de)
DE (1) DE69431531T2 (de)
WO (1) WO1995002687A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683906A (en) * 1994-09-09 1997-11-04 Zymogenetics, Inc. Preparation of immortalized cells
WO1996014400A1 (en) 1994-11-08 1996-05-17 Bradley Michael John Stringer Human cell-lines
GB9515327D0 (en) * 1995-07-26 1995-09-20 Univ London Site-directed bone formation
US6713247B1 (en) * 1996-09-03 2004-03-30 Signal Pharmaceuticials, Inc. Human CNS cell lines and methods of use therefor
JP2002502822A (ja) * 1998-02-10 2002-01-29 オレゴン ヘルス サイエンシーズ ユニバーシティー 骨芽細胞の前駆細胞による骨欠損の治療
US6995018B1 (en) * 1999-04-09 2006-02-07 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Complex formed by N-linked glycoproteins (SIBLINGS)and Factor H
BR0014183A (pt) * 1999-09-13 2002-05-14 American Home Pruducts Corp Composições farmaceuticas e metodos de uso de proteìna relacionada frizzled secretada
AU2005201918B2 (en) * 1999-09-13 2009-01-22 Wyeth Pharmaceutical compositions and methods of using secreted frizzled related protein
EP1207196A1 (de) * 2000-10-27 2002-05-22 Societe Des Produits Nestle S.A. Immortalisierte pre-osteoblasten und verfahren zur deren herstellung
US20030036194A1 (en) * 2001-07-06 2003-02-20 Chunhui Xu Mesenchymal cells derived from human embryonic stem cells
CH695985A5 (de) * 2002-01-21 2006-11-15 Straumann Holding Ag Oberflächenmodifizierte Implantate.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03504799A (ja) * 1988-04-12 1991-10-24 マサチューセッツ・インスティチュート・オブ・テクノロジー 真核細胞の細胞型を操作する方法
US5028425A (en) * 1988-07-07 1991-07-02 The United States Of America As Represented By The Department Of Health And Human Services Synthetic vaccine against P. falciparum malaria

Also Published As

Publication number Publication date
EP0743982A1 (de) 1996-11-27
US5693511A (en) 1997-12-02
CA2166973A1 (en) 1995-01-26
WO1995002687A1 (en) 1995-01-26
CA2166973C (en) 2007-01-30
DE69431531T2 (de) 2003-02-27
EP0743982B1 (de) 2002-10-09
US5681701A (en) 1997-10-28
DE69431531D1 (de) 2002-11-14
AU7327694A (en) 1995-02-13

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Legal Events

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