ATE226728T1 - Verfahren und testsätze zur erzeugung von licht von einer acridan-verbindung - Google Patents
Verfahren und testsätze zur erzeugung von licht von einer acridan-verbindungInfo
- Publication number
- ATE226728T1 ATE226728T1 AT95931030T AT95931030T ATE226728T1 AT E226728 T1 ATE226728 T1 AT E226728T1 AT 95931030 T AT95931030 T AT 95931030T AT 95931030 T AT95931030 T AT 95931030T AT E226728 T1 ATE226728 T1 AT E226728T1
- Authority
- AT
- Austria
- Prior art keywords
- assay
- reaction
- chemiluminescent
- compound
- acridan
- Prior art date
Links
- -1 ACRIDAN COMPOUND Chemical class 0.000 title abstract 3
- HJCUTNIGJHJGCF-UHFFFAOYSA-N acridan acid Natural products C1=CC=C2CC3=CC=CC=C3NC2=C1 HJCUTNIGJHJGCF-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000003556 assay Methods 0.000 abstract 4
- 238000006243 chemical reaction Methods 0.000 abstract 4
- 102000003992 Peroxidases Human genes 0.000 abstract 2
- 108020003215 DNA Probes Proteins 0.000 abstract 1
- 239000003298 DNA probe Substances 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 238000009825 accumulation Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/02—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with only hydrogen, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30046294A | 1994-09-02 | 1994-09-02 | |
| PCT/US1995/011031 WO1996007912A1 (en) | 1994-09-02 | 1995-08-30 | Novel method and kits for producing light from an acridan compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE226728T1 true ATE226728T1 (de) | 2002-11-15 |
Family
ID=23159199
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95931030T ATE226728T1 (de) | 1994-09-02 | 1995-08-30 | Verfahren und testsätze zur erzeugung von licht von einer acridan-verbindung |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0778946B1 (de) |
| JP (1) | JPH10508191A (de) |
| AT (1) | ATE226728T1 (de) |
| AU (1) | AU3461995A (de) |
| CA (1) | CA2197669A1 (de) |
| DE (1) | DE69528661T2 (de) |
| WO (1) | WO1996007912A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6017769A (en) * | 1998-06-17 | 2000-01-25 | Lumigen, Inc. | Non-enzymatic methods of generating chemiluminescence from acridan alkenes |
| US6162610A (en) * | 1998-09-11 | 2000-12-19 | Tropix, Inc. | Xanthan-ester and acridan substrates for horseradish peroxidase |
| US7906293B2 (en) | 2007-04-09 | 2011-03-15 | Abbott Laboratories | Acridinium phenyl esters useful in the analysis of biological |
| CN115993457B (zh) * | 2023-03-22 | 2023-06-09 | 广州科方生物技术股份有限公司 | 一种用于化学发光免疫分析仪检测光子含量的发光剂及其制配方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4918192A (en) * | 1986-10-06 | 1990-04-17 | Ciba Corning Diagnostics Corp. | Polysubstituted aryl acridinium esters |
| US5283334A (en) * | 1987-12-31 | 1994-02-01 | London Diagnostics, Inc. | Side-chain functional chemiluminescent labels and their conjugates, and assays therefrom |
| US5491072A (en) * | 1993-05-17 | 1996-02-13 | Lumigen, Inc. | N-alkylacridan carboxyl derivatives useful for chemiluminescent detection |
-
1995
- 1995-08-30 AT AT95931030T patent/ATE226728T1/de not_active IP Right Cessation
- 1995-08-30 DE DE69528661T patent/DE69528661T2/de not_active Expired - Lifetime
- 1995-08-30 WO PCT/US1995/011031 patent/WO1996007912A1/en not_active Ceased
- 1995-08-30 AU AU34619/95A patent/AU3461995A/en not_active Abandoned
- 1995-08-30 EP EP95931030A patent/EP0778946B1/de not_active Expired - Lifetime
- 1995-08-30 CA CA002197669A patent/CA2197669A1/en not_active Abandoned
- 1995-08-30 JP JP8509567A patent/JPH10508191A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA2197669A1 (en) | 1996-03-14 |
| EP0778946A4 (de) | 1999-01-27 |
| EP0778946B1 (de) | 2002-10-23 |
| JPH10508191A (ja) | 1998-08-18 |
| WO1996007912A1 (en) | 1996-03-14 |
| AU3461995A (en) | 1996-03-27 |
| DE69528661D1 (de) | 2002-11-28 |
| EP0778946A1 (de) | 1997-06-18 |
| DE69528661T2 (de) | 2003-07-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |