ATE227276T1 - Neue pyrimidinderivate - Google Patents
Neue pyrimidinderivateInfo
- Publication number
- ATE227276T1 ATE227276T1 AT98934105T AT98934105T ATE227276T1 AT E227276 T1 ATE227276 T1 AT E227276T1 AT 98934105 T AT98934105 T AT 98934105T AT 98934105 T AT98934105 T AT 98934105T AT E227276 T1 ATE227276 T1 AT E227276T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrimidine derivatives
- new pyrimidine
- new
- purinoceptor
- transmembrane
- Prior art date
Links
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical class C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
- 229940123344 GPR antagonist Drugs 0.000 abstract 1
- 102000007466 Purinergic P2 Receptors Human genes 0.000 abstract 1
- 108010085249 Purinergic P2 Receptors Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9702794A SE9702794D0 (sv) | 1997-07-24 | 1997-07-24 | New compounds |
| PCT/SE1998/001391 WO1999005123A1 (en) | 1997-07-24 | 1998-07-15 | Novel pyrimidin derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE227276T1 true ATE227276T1 (de) | 2002-11-15 |
Family
ID=20407823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98934105T ATE227276T1 (de) | 1997-07-24 | 1998-07-15 | Neue pyrimidinderivate |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6200981B1 (de) |
| EP (1) | EP1000038B1 (de) |
| JP (1) | JP2001510833A (de) |
| AT (1) | ATE227276T1 (de) |
| AU (1) | AU8370498A (de) |
| DE (1) | DE69809242D1 (de) |
| SE (1) | SE9702794D0 (de) |
| WO (1) | WO1999005123A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1042320B1 (de) * | 1997-11-21 | 2002-02-13 | AstraZeneca UK Limited | Neue verbindungen, welche antagonisten sind für p2-purinorezeptor 7-transmembran (tm) g-protein gekoppelte rezeptoren |
| US7179481B2 (en) * | 2002-09-19 | 2007-02-20 | Kimberly-Clark Worldwide, Inc. | Vaginal health products |
| US7056889B2 (en) | 2002-12-16 | 2006-06-06 | Kimberly-Clark, Worldwide, Inc. | Compounds that bind P2Y2 or P2Y1 receptors |
| US7098189B2 (en) * | 2002-12-16 | 2006-08-29 | Kimberly-Clark Worldwide, Inc. | Wound and skin care compositions |
| US7485666B2 (en) * | 2004-06-17 | 2009-02-03 | Kimberly-Clark Worldwide, Inc. | Vaginal health products |
| RS53599B1 (sr) | 2005-05-10 | 2015-02-27 | Intermune, Inc. | Piridon derivati za modulaciju stresom aktiviranog sistema proteinskih kinaza |
| EP1893603B1 (de) | 2005-06-02 | 2009-10-14 | F. Hoffmann-La Roche AG | Piperidin-4-yl-amidderivate und ihre verwendung als antagonisten des sst-rezeptors vom subtyp 5 |
| JP5627574B2 (ja) | 2008-06-03 | 2014-11-19 | インターミューン， インコーポレイテッド | 炎症性および線維性疾患を治療するための化合物および方法 |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| CN106459042B (zh) | 2014-04-02 | 2019-06-28 | 英特穆恩公司 | 抗纤维化吡啶酮类 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6930196A (en) * | 1995-09-12 | 1997-04-01 | Bayer Aktiengesellschaft | Uracil derivative |
-
1997
- 1997-07-24 SE SE9702794A patent/SE9702794D0/xx unknown
-
1998
- 1998-07-15 US US09/155,091 patent/US6200981B1/en not_active Expired - Fee Related
- 1998-07-15 EP EP98934105A patent/EP1000038B1/de not_active Expired - Lifetime
- 1998-07-15 JP JP2000504122A patent/JP2001510833A/ja active Pending
- 1998-07-15 WO PCT/SE1998/001391 patent/WO1999005123A1/en not_active Ceased
- 1998-07-15 AT AT98934105T patent/ATE227276T1/de not_active IP Right Cessation
- 1998-07-15 DE DE69809242T patent/DE69809242D1/de not_active Expired - Lifetime
- 1998-07-15 AU AU83704/98A patent/AU8370498A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US6200981B1 (en) | 2001-03-13 |
| DE69809242D1 (de) | 2002-12-12 |
| EP1000038A1 (de) | 2000-05-17 |
| JP2001510833A (ja) | 2001-08-07 |
| WO1999005123A1 (en) | 1999-02-04 |
| EP1000038B1 (de) | 2002-11-06 |
| AU8370498A (en) | 1999-02-16 |
| SE9702794D0 (sv) | 1997-07-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |