ATE227582T1 - Chemokin rezeptor antagonist und cyclosporin in kombinationstherapie - Google Patents

Chemokin rezeptor antagonist und cyclosporin in kombinationstherapie

Info

Publication number: ATE227582T1
Authority: AT; Austria
Prior art keywords: cyclosporin; receptor antagonist; combination therapy; chemokine receptor; chemokine
Prior art date: 1998-09-18

Application number

AT99948760T

Other languages

English (en)

Inventor

Hermann-Joseph Grone

Peter J Nelson

Amanda Proudfoot

Timothy N C Wells

Original Assignee

Applied Research Systems

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-18

Filing date

1999-09-16

Publication date

2002-11-15

1999-09-16 Application filed by Applied Research Systems filed Critical Applied Research Systems

2002-11-15 Application granted granted Critical

2002-11-15 Publication of ATE227582T1 publication Critical patent/ATE227582T1/de

Links

229940122444 Chemokine receptor antagonist Drugs 0.000 title 1
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
229930105110 Cyclosporin A Natural products 0.000 title 1
108010036949 Cyclosporine Proteins 0.000 title 1
239000002559 chemokine receptor antagonist Substances 0.000 title 1
229960001265 ciclosporin Drugs 0.000 title 1
238000002648 combination therapy Methods 0.000 title 1
229930182912 cyclosporin Natural products 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Toxicology (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Transplantation (AREA)
Epidemiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

AT99948760T 1998-09-18 1999-09-16 Chemokin rezeptor antagonist und cyclosporin in kombinationstherapie ATE227582T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98117697A EP1000626A1 (de)	1998-09-18	1998-09-18	Kombination von chemokin-rezeptor antagonisten und cyclosporin zur therapie
PCT/EP1999/006844 WO2000016796A1 (en)	1998-09-18	1999-09-16	Chemokine receptor antagonist and cyclosporin in combined therapy

Publications (1)

Publication Number	Publication Date
ATE227582T1 true ATE227582T1 (de)	2002-11-15

Family

ID=8232654

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99948760T ATE227582T1 (de)	1998-09-18	1999-09-16	Chemokin rezeptor antagonist und cyclosporin in kombinationstherapie

Country Status (23)

Country	Link
US (1)	US6902728B1 (de)
EP (2)	EP1000626A1 (de)
JP (1)	JP2003519082A (de)
KR (1)	KR100613950B1 (de)
CN (1)	CN1177613C (de)
AR (1)	AR021810A1 (de)
AT (1)	ATE227582T1 (de)
AU (1)	AU766595B2 (de)
BR (1)	BR9913846A (de)
CA (1)	CA2344370A1 (de)
DE (1)	DE69903964T2 (de)
DK (1)	DK1113811T3 (de)
EA (1)	EA003181B1 (de)
EE (1)	EE04705B1 (de)
ES (1)	ES2186411T3 (de)
HK (1)	HK1041225B (de)
IL (2)	IL141899A0 (de)
NO (1)	NO20011371D0 (de)
PT (1)	PT1113811E (de)
SI (1)	SI1113811T1 (de)
UA (1)	UA60379C2 (de)
WO (1)	WO2000016796A1 (de)
ZA (1)	ZA200101909B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7259136B2 (en)	1999-04-30	2007-08-21	Amylin Pharmaceuticals, Inc.	Compositions and methods for treating peripheral vascular disease
US6740636B2 (en)	2000-07-31	2004-05-25	Schering Aktiengesellschaft	Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection
LT5132B (lt)	2000-07-31	2004-05-25	Schering Aktiengesellschaft	Nepeptidiniai ccr1 receptorių antagonistai derinyje su ciklosporinu a širdies transplanto atmetimui gydyti
CA2695237A1 (en)	2007-08-02	2009-04-30	Novimmune S.A.	Anti-rantes antibodies and methods of use thereof
WO2017040520A1 (en)	2015-08-31	2017-03-09	Hitachi Chemical Co., Ltd.	Molecular methods for assessing urothelial disease
US20180265914A1 (en) *	2015-08-31	2018-09-20	Hitachi Chemical Co., Ltd.	Molecular methods for assessing post kidney transplant complications

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CZ290850B6 (cs) *	1994-12-08	2002-10-16	Glaxo Group Limited	Polypeptid, způsob jeho výroby, kódující DNA nebo RNA, vektor a buňka
AU712606B2 (en) *	1995-08-09	1999-11-11	Schering Corporation	Combined use of interleukin-10 and cyclosporin for immunosuppression therapy
EP0927167A1 (de) *	1996-08-14	1999-07-07	Warner-Lambert Company	2-phenylbenzimidazol-derivate als mcp-1 antagonisten
WO1998006751A1 (en) *	1996-08-16	1998-02-19	Research Corporation Technologies, Inc.	Mcp-3, rantes and mip-1alpha receptor antagonists

1998
- 1998-09-18 EP EP98117697A patent/EP1000626A1/de not_active Withdrawn
1999
- 1999-09-16 EE EEP200100159A patent/EE04705B1/xx not_active IP Right Cessation
- 1999-09-16 AR ARP990104655A patent/AR021810A1/es unknown
- 1999-09-16 UA UA2001042570A patent/UA60379C2/uk unknown
- 1999-09-16 EA EA200100366A patent/EA003181B1/ru not_active IP Right Cessation
- 1999-09-16 ZA ZA200101909A patent/ZA200101909B/xx unknown
- 1999-09-16 US US09/787,335 patent/US6902728B1/en not_active Expired - Fee Related
- 1999-09-16 EP EP99948760A patent/EP1113811B1/de not_active Expired - Lifetime
- 1999-09-16 IL IL141899??A patent/IL141899A0/xx active IP Right Grant
- 1999-09-16 DE DE69903964T patent/DE69903964T2/de not_active Expired - Lifetime
- 1999-09-16 AU AU61914/99A patent/AU766595B2/en not_active Ceased
- 1999-09-16 CN CNB998111252A patent/CN1177613C/zh not_active Expired - Fee Related
- 1999-09-16 BR BR9913846-8A patent/BR9913846A/pt not_active Application Discontinuation
- 1999-09-16 KR KR1020017003199A patent/KR100613950B1/ko not_active Expired - Fee Related
- 1999-09-16 DK DK99948760T patent/DK1113811T3/da active
- 1999-09-16 SI SI9930157T patent/SI1113811T1/xx unknown
- 1999-09-16 PT PT99948760T patent/PT1113811E/pt unknown
- 1999-09-16 CA CA002344370A patent/CA2344370A1/en not_active Abandoned
- 1999-09-16 AT AT99948760T patent/ATE227582T1/de active
- 1999-09-16 WO PCT/EP1999/006844 patent/WO2000016796A1/en not_active Ceased
- 1999-09-16 JP JP2000573757A patent/JP2003519082A/ja not_active Withdrawn
- 1999-09-16 ES ES99948760T patent/ES2186411T3/es not_active Expired - Lifetime
- 1999-09-16 HK HK02103034.0A patent/HK1041225B/zh not_active IP Right Cessation
2001
- 2001-03-08 IL IL141899A patent/IL141899A/en not_active IP Right Cessation
- 2001-03-16 NO NO20011371A patent/NO20011371D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
HK1041225B (zh)	2005-04-22
EP1000626A1 (de)	2000-05-17
CN1177613C (zh)	2004-12-01
CA2344370A1 (en)	2000-03-30
ES2186411T3 (es)	2003-05-01
HK1041225A1 (en)	2002-07-05
US6902728B1 (en)	2005-06-07
IL141899A0 (en)	2002-03-10
NO20011371L (no)	2001-03-16
UA60379C2 (uk)	2003-10-15
EP1113811A1 (de)	2001-07-11
KR100613950B1 (ko)	2006-08-18
PT1113811E (pt)	2003-03-31
SI1113811T1 (en)	2003-04-30
IL141899A (en)	2007-12-03
EP1113811B1 (de)	2002-11-13
DE69903964D1 (en)	2002-12-19
DK1113811T3 (da)	2003-03-10
WO2000016796A1 (en)	2000-03-30
NO20011371D0 (no)	2001-03-16
EA003181B1 (ru)	2003-02-27
EE04705B1 (et)	2006-10-16
CN1319021A (zh)	2001-10-24
AR021810A1 (es)	2002-08-07
BR9913846A (pt)	2001-06-05
KR20010075060A (ko)	2001-08-09
EE200100159A (et)	2002-08-15
AU766595B2 (en)	2003-10-16
EA200100366A1 (ru)	2001-08-27
ZA200101909B (en)	2001-09-11
AU6191499A (en)	2000-04-10
JP2003519082A (ja)	2003-06-17
DE69903964T2 (de)	2003-03-27

Legal Events

Date

Code

Title

Description

2003-02-15

UEP

Publication of translation of european patent specification

Ref document number: 1113811

Country of ref document: EP

2011-04-15

EEFA

Change of the company name

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DE69841509D1 (de)	2010-04-01	Lektrodenfomstück und elektrochemische elemente
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DE69708461D1 (de)	2002-01-03	Bioresponsive pharmakologisch aktive polymere und daraus hergestellte gegenstände
NO975976L (no)	1998-06-22	Vitronektinreseptor-antagonister, fremstilling samt anvendelse derav
DE69831750D1 (de)	2006-02-09	Biozide und biozide tücher
DE69903961D1 (de)	2002-12-19	Muscarinagonisten und antagonisten
DE59903751D1 (de)	2003-01-23	2',2'-difluornucleoside zur immunosuppressiven therapie und kombinationspräparate
NO20004274D0 (no)	2000-08-25	Proteaseaktivert reseptor 4 og anvendelse derav
ATE368742T1 (de)	2007-08-15	Aminoterminalen verkürzten c-c chemokine und als chemokine antagonist
TR199701645A3 (tr)	1998-07-21	Vitronektin reseptör antagonistleri,bunlarin imalati ve kullanimi
DE60004989D1 (de)	2003-10-09	Fluoroalkansulfonylazid-monomere und copolymere davon
CZ2000522A3 (cs)	2000-09-13	Farmaceutický prostředek na bázi piperidinalkanolového antihistaminika a použití
GB9820014D0 (en)	1998-11-04	Receptor antagonists and uses thereof
ATE227582T1 (de)	2002-11-15	Chemokin rezeptor antagonist und cyclosporin in kombinationstherapie
PL363048A1 (en)	2004-11-15	Azabicyclic derivatives and their therapeutic use
DE69932577D1 (de)	2006-09-14	Stangenbehandlungsgerät und Stangenladegerät
DE69822446D1 (de)	2004-04-22	Cyclosporin derivate und deren verwendung
ZA981782B (en)	1999-03-03	The use of levobupivacaine in combination with other drugs
HU0000744D0 (en)	2000-04-28	Transposing unit and flaw
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FR2757403B3 (fr)	1999-02-12	Coussin thermotherapeutique et/ou frigotherapeutique plus
GB9818018D0 (en)	1998-10-14	Microparticles and their use in therapy
GB9810427D0 (en)	1998-07-15	Levobupivacaine and its use
SE9803771D0 (sv)	1998-11-05	Pharmaceutical composition and use