ATE227582T1 - Chemokin rezeptor antagonist und cyclosporin in kombinationstherapie - Google Patents

Chemokin rezeptor antagonist und cyclosporin in kombinationstherapie

Info

Publication number: ATE227582T1
Authority: AT; Austria
Prior art keywords: cyclosporin; receptor antagonist; combination therapy; chemokine receptor; chemokine
Prior art date: 1998-09-18

Application number

AT99948760T

Other languages

English (en)

Inventor

Hermann-Joseph Grone

Peter J Nelson

Amanda Proudfoot

Timothy N C Wells

Original Assignee

Applied Research Systems

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-18

Filing date

1999-09-16

Publication date

2002-11-15

1999-09-16 Application filed by Applied Research Systems filed Critical Applied Research Systems

2002-11-15 Application granted granted Critical

2002-11-15 Publication of ATE227582T1 publication Critical patent/ATE227582T1/de

Links

229940122444 Chemokine receptor antagonist Drugs 0.000 title 1
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
229930105110 Cyclosporin A Natural products 0.000 title 1
108010036949 Cyclosporine Proteins 0.000 title 1
239000002559 chemokine receptor antagonist Substances 0.000 title 1
229960001265 ciclosporin Drugs 0.000 title 1
238000002648 combination therapy Methods 0.000 title 1
229930182912 cyclosporin Natural products 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Toxicology (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Transplantation (AREA)
Epidemiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

AT99948760T 1998-09-18 1999-09-16 Chemokin rezeptor antagonist und cyclosporin in kombinationstherapie ATE227582T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98117697A EP1000626A1 (de)	1998-09-18	1998-09-18	Kombination von chemokin-rezeptor antagonisten und cyclosporin zur therapie
PCT/EP1999/006844 WO2000016796A1 (en)	1998-09-18	1999-09-16	Chemokine receptor antagonist and cyclosporin in combined therapy

Publications (1)

Publication Number	Publication Date
ATE227582T1 true ATE227582T1 (de)	2002-11-15

Family

ID=8232654

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99948760T ATE227582T1 (de)	1998-09-18	1999-09-16	Chemokin rezeptor antagonist und cyclosporin in kombinationstherapie

Country Status (23)

Country	Link
US (1)	US6902728B1 (de)
EP (2)	EP1000626A1 (de)
JP (1)	JP2003519082A (de)
KR (1)	KR100613950B1 (de)
CN (1)	CN1177613C (de)
AR (1)	AR021810A1 (de)
AT (1)	ATE227582T1 (de)
AU (1)	AU766595B2 (de)
BR (1)	BR9913846A (de)
CA (1)	CA2344370A1 (de)
DE (1)	DE69903964T2 (de)
DK (1)	DK1113811T3 (de)
EA (1)	EA003181B1 (de)
EE (1)	EE04705B1 (de)
ES (1)	ES2186411T3 (de)
HK (1)	HK1041225B (de)
IL (2)	IL141899A0 (de)
NO (1)	NO20011371L (de)
PT (1)	PT1113811E (de)
SI (1)	SI1113811T1 (de)
UA (1)	UA60379C2 (de)
WO (1)	WO2000016796A1 (de)
ZA (1)	ZA200101909B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7259136B2 (en)	1999-04-30	2007-08-21	Amylin Pharmaceuticals, Inc.	Compositions and methods for treating peripheral vascular disease
US6740636B2 (en)	2000-07-31	2004-05-25	Schering Aktiengesellschaft	Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection
LT5132B (lt)	2000-07-31	2004-05-25	Schering Aktiengesellschaft	Nepeptidiniai ccr1 receptorių antagonistai derinyje su ciklosporinu a širdies transplanto atmetimui gydyti
ES2453592T3 (es)	2007-08-02	2014-04-08	Novimmune Sa	Anticuerpos anti-RANTES y métodos de uso de los mismos
JP6733968B2 (ja) *	2015-08-31	2020-08-05	日立化成株式会社	腎移植後合併症を評価するための分子法
DE112016003948T5 (de)	2015-08-31	2018-05-09	City Of Sapporo	Molekulare verfahren zum beurteilen einer urothelialen erkrankung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI972433A0 (fi) *	1994-12-08	1997-06-06	Glaxo Group Ltd	Rantes-peptidi ja fragmentteja sekä tätä sisältäviä tulehduksen hoitoon soveltuvia koostumuksia
CA2228379A1 (en) *	1995-08-09	1997-02-20	Schering Corporation	Combined use of interleukin-10 and cyclosporin for immunosuppression therapy
WO1998006703A1 (en) *	1996-08-14	1998-02-19	Warner-Lambert Company	2-phenyl benzimidazole derivatives as mcp-1 antagonists
WO1998006751A1 (en) *	1996-08-16	1998-02-19	Research Corporation Technologies, Inc.	Mcp-3, rantes and mip-1alpha receptor antagonists

1998
- 1998-09-18 EP EP98117697A patent/EP1000626A1/de not_active Withdrawn
1999
- 1999-09-16 KR KR1020017003199A patent/KR100613950B1/ko not_active Expired - Fee Related
- 1999-09-16 HK HK02103034.0A patent/HK1041225B/zh not_active IP Right Cessation
- 1999-09-16 AT AT99948760T patent/ATE227582T1/de active
- 1999-09-16 CN CNB998111252A patent/CN1177613C/zh not_active Expired - Fee Related
- 1999-09-16 EE EEP200100159A patent/EE04705B1/xx not_active IP Right Cessation
- 1999-09-16 ES ES99948760T patent/ES2186411T3/es not_active Expired - Lifetime
- 1999-09-16 IL IL141899??A patent/IL141899A0/xx active IP Right Grant
- 1999-09-16 JP JP2000573757A patent/JP2003519082A/ja not_active Withdrawn
- 1999-09-16 SI SI9930157T patent/SI1113811T1/xx unknown
- 1999-09-16 WO PCT/EP1999/006844 patent/WO2000016796A1/en not_active Ceased
- 1999-09-16 EA EA200100366A patent/EA003181B1/ru not_active IP Right Cessation
- 1999-09-16 AU AU61914/99A patent/AU766595B2/en not_active Ceased
- 1999-09-16 AR ARP990104655A patent/AR021810A1/es unknown
- 1999-09-16 DK DK99948760T patent/DK1113811T3/da active
- 1999-09-16 EP EP99948760A patent/EP1113811B1/de not_active Expired - Lifetime
- 1999-09-16 ZA ZA200101909A patent/ZA200101909B/xx unknown
- 1999-09-16 DE DE69903964T patent/DE69903964T2/de not_active Expired - Lifetime
- 1999-09-16 PT PT99948760T patent/PT1113811E/pt unknown
- 1999-09-16 UA UA2001042570A patent/UA60379C2/uk unknown
- 1999-09-16 BR BR9913846-8A patent/BR9913846A/pt not_active Application Discontinuation
- 1999-09-16 CA CA002344370A patent/CA2344370A1/en not_active Abandoned
- 1999-09-16 US US09/787,335 patent/US6902728B1/en not_active Expired - Fee Related
2001
- 2001-03-08 IL IL141899A patent/IL141899A/en not_active IP Right Cessation
- 2001-03-16 NO NO20011371A patent/NO20011371L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO2000016796A1 (en)	2000-03-30
IL141899A (en)	2007-12-03
EE04705B1 (et)	2006-10-16
JP2003519082A (ja)	2003-06-17
CN1177613C (zh)	2004-12-01
EP1113811B1 (de)	2002-11-13
EE200100159A (et)	2002-08-15
PT1113811E (pt)	2003-03-31
CN1319021A (zh)	2001-10-24
HK1041225A1 (en)	2002-07-05
BR9913846A (pt)	2001-06-05
ES2186411T3 (es)	2003-05-01
AU766595B2 (en)	2003-10-16
KR20010075060A (ko)	2001-08-09
EP1113811A1 (de)	2001-07-11
AR021810A1 (es)	2002-08-07
NO20011371D0 (no)	2001-03-16
DE69903964T2 (de)	2003-03-27
EA003181B1 (ru)	2003-02-27
EP1000626A1 (de)	2000-05-17
DE69903964D1 (en)	2002-12-19
KR100613950B1 (ko)	2006-08-18
CA2344370A1 (en)	2000-03-30
US6902728B1 (en)	2005-06-07
DK1113811T3 (da)	2003-03-10
HK1041225B (zh)	2005-04-22
NO20011371L (no)	2001-03-16
AU6191499A (en)	2000-04-10
UA60379C2 (uk)	2003-10-15
IL141899A0 (en)	2002-03-10
ZA200101909B (en)	2001-09-11
SI1113811T1 (en)	2003-04-30
EA200100366A1 (ru)	2001-08-27

Legal Events

Date

Code

Title

Description

2003-02-15

UEP

Publication of translation of european patent specification

Ref document number: 1113811

Country of ref document: EP

2011-04-15

EEFA

Change of the company name

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ATE449849T1 (de)	2009-12-15	Ob rezeptor-variante und liganden
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DE69832657D1 (de)	2006-01-12	Empfangseinrichtungen und Empfangsverfahren
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ATE227724T1 (de)	2002-11-15	Muscarinagonisten und antagonisten
DE69831750D1 (de)	2006-02-09	Biozide und biozide tücher
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TR199701645A3 (tr)	1998-07-21	Vitronektin reseptör antagonistleri,bunlarin imalati ve kullanimi
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ZA981782B (en)	1999-03-03	The use of levobupivacaine in combination with other drugs
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