ATE227703T1 - Aminotetralon-derivate und verfahren zu deren herstellung - Google Patents

Aminotetralon-derivate und verfahren zu deren herstellung

Info

Publication number
ATE227703T1
ATE227703T1 AT96903202T AT96903202T ATE227703T1 AT E227703 T1 ATE227703 T1 AT E227703T1 AT 96903202 T AT96903202 T AT 96903202T AT 96903202 T AT96903202 T AT 96903202T AT E227703 T1 ATE227703 T1 AT E227703T1
Authority
AT
Austria
Prior art keywords
production
aminotetralone
preparation
derivative
derivatives
Prior art date
Application number
AT96903202T
Other languages
English (en)
Inventor
Shinji Kamihara
Kazuaki Kanai
Shigeru Noguchi
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Application granted granted Critical
Publication of ATE227703T1 publication Critical patent/ATE227703T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C07C233/15—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/41—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT96903202T 1995-02-22 1996-02-21 Aminotetralon-derivate und verfahren zu deren herstellung ATE227703T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3337695 1995-02-22
PCT/JP1996/000390 WO1996026181A1 (en) 1995-02-22 1996-02-21 Aminotetralone derivatives and process for producing the same

Publications (1)

Publication Number Publication Date
ATE227703T1 true ATE227703T1 (de) 2002-11-15

Family

ID=12384880

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96903202T ATE227703T1 (de) 1995-02-22 1996-02-21 Aminotetralon-derivate und verfahren zu deren herstellung

Country Status (14)

Country Link
US (1) US5849945A (de)
EP (1) EP0811603B1 (de)
KR (1) KR100406020B1 (de)
CN (1) CN1104409C (de)
AT (1) ATE227703T1 (de)
CA (1) CA2213201A1 (de)
DE (1) DE69624796T2 (de)
DK (1) DK0811603T3 (de)
EA (1) EA000122B1 (de)
ES (1) ES2187634T3 (de)
FI (1) FI973434A7 (de)
NO (1) NO973842D0 (de)
PT (1) PT811603E (de)
WO (1) WO1996026181A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8575361B2 (en) 2010-03-02 2013-11-05 Concert Pharmaceuticals Inc. Tetrahydronaphthalene derivatives
EP2542534A1 (de) 2010-03-02 2013-01-09 Concert Pharmaceuticals Inc. Deuterierte tetrahydronaphthalenderivate
JP7248578B2 (ja) 2017-08-31 2023-03-29 第一三共株式会社 抗体－薬物コンジュゲートの新規製造方法
CN118221763A (zh) 2019-03-29 2024-06-21 免疫医疗有限公司 化合物及其缀合物
CN114516808B (zh) * 2020-11-20 2024-01-19 华东师范大学 一种氨基保护的苯并环酮类化合物的制备方法
CN115197088A (zh) * 2021-04-02 2022-10-18 江苏恒瑞医药股份有限公司 一种喜树碱衍生物中间体的制备方法
US20240343678A1 (en) * 2021-08-17 2024-10-17 Jiangsu Mabwell Health Pharmaceutical R&D Co., Ltd. Method for synthesizing 5,8-diamino-3,4-dihydro-2h-1-naphthalenone and intermediate compound used therein
CN115724758B (zh) * 2021-08-24 2024-12-27 杭州中美华东制药有限公司 喜树碱衍生物中间体及其合成方法和利用中间体合成喜树碱衍生物的方法
US20250059143A1 (en) * 2021-10-26 2025-02-20 Shanghai Best-Link Bioscience, Llc Camptothecin derivative intermediate, and preparation method therefor and use thereof
CN116375594A (zh) * 2021-12-24 2023-07-04 山东恒屹生物医药有限公司 一种依喜替康中间体制备工艺

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3008226B2 (ja) * 1991-01-16 2000-02-14 第一製薬株式会社 六環性化合物
US5637770A (en) * 1991-01-16 1997-06-10 Daiichi Pharmaceutical Co., Ltd. Hexa-cyclic compound
JP3359955B2 (ja) * 1992-07-16 2002-12-24 第一製薬株式会社 抗腫瘍剤

Also Published As

Publication number Publication date
CN1175943A (zh) 1998-03-11
FI973434L (fi) 1997-08-21
US5849945A (en) 1998-12-15
EA199700189A1 (ru) 1998-02-26
FI973434A0 (fi) 1997-08-21
EP0811603B1 (de) 2002-11-13
PT811603E (pt) 2003-03-31
CN1104409C (zh) 2003-04-02
DE69624796D1 (de) 2002-12-19
FI973434A7 (fi) 1997-08-21
EP0811603A1 (de) 1997-12-10
KR19980702346A (ko) 1998-07-15
KR100406020B1 (ko) 2004-03-20
EP0811603A4 (de) 1998-10-07
NO973842L (no) 1997-08-21
DE69624796T2 (de) 2003-04-03
DK0811603T3 (da) 2002-12-16
CA2213201A1 (en) 1996-08-29
ES2187634T3 (es) 2003-06-16
NO973842D0 (no) 1997-08-21
WO1996026181A1 (en) 1996-08-29
EA000122B1 (ru) 1998-08-27

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