ATE242241T1 - Imidazopyridinderivate und verfahren zu ihrer herstellung - Google Patents
Imidazopyridinderivate und verfahren zu ihrer herstellungInfo
- Publication number
- ATE242241T1 ATE242241T1 AT99203478T AT99203478T ATE242241T1 AT E242241 T1 ATE242241 T1 AT E242241T1 AT 99203478 T AT99203478 T AT 99203478T AT 99203478 T AT99203478 T AT 99203478T AT E242241 T1 ATE242241 T1 AT E242241T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- imidazopyridine derivatives
- chem
- compound
- formula
- Prior art date
Links
- 150000005232 imidazopyridines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- HHLFWLYXYJOTON-UHFFFAOYSA-N glyoxylic acid Chemical compound OC(=O)C=O HHLFWLYXYJOTON-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Inert Electrodes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12649499P | 1999-03-25 | 1999-03-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE242241T1 true ATE242241T1 (de) | 2003-06-15 |
Family
ID=22425138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99203478T ATE242241T1 (de) | 1999-03-25 | 1999-10-22 | Imidazopyridinderivate und verfahren zu ihrer herstellung |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6242460B1 (de) |
| EP (1) | EP1038875B1 (de) |
| AT (1) | ATE242241T1 (de) |
| DE (1) | DE69908546T2 (de) |
| DK (1) | DK1038875T3 (de) |
| ES (1) | ES2195510T3 (de) |
| PT (1) | PT1038875E (de) |
| SI (1) | SI1038875T1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001078725A2 (en) | 2000-04-13 | 2001-10-25 | Synthon B.V. | Modified release formulations containing a hypnotic agent |
| ES2239558T3 (es) * | 2000-04-24 | 2007-04-01 | Teva Pharmaceutical Industries Ltd. | Hemitartrato de zolpidem micronizado. |
| EP1475093B1 (de) * | 2000-04-24 | 2006-09-06 | Teva Pharmaceutical Industries Ltd. | Mikronisierter zolpidem Hemitartrat |
| US20030165566A1 (en) * | 2002-01-10 | 2003-09-04 | O'toole Edel | Sedative non-benzodiazepine formulations |
| ES2320758T3 (es) * | 2002-12-18 | 2009-05-28 | Mallinckrodt Inc. | Sintesis de heteroaril acetamidas. |
| GB0329918D0 (en) * | 2003-12-24 | 2004-01-28 | West Pharm Serv Drug Res Ltd | Intranasal compositions |
| EP1715853A4 (de) * | 2004-02-17 | 2012-07-18 | Transcept Pharmaceuticals Inc | Zusammensetzungen zur abgabe von hypnotika im bereich der mundschleimhäute und verwendungsverfahren davon |
| US20080262025A1 (en) * | 2004-07-16 | 2008-10-23 | Yatendra Kumar | Processes for the Preparation of Zolpidem and its Hemitartrate |
| US20070287740A1 (en) * | 2005-05-25 | 2007-12-13 | Transcept Pharmaceuticals, Inc. | Compositions and methods of treating middle-of-the night insomnia |
| US20070225322A1 (en) * | 2005-05-25 | 2007-09-27 | Transoral Pharmaceuticals, Inc. | Compositions and methods for treating middle-of-the night insomnia |
| US20070123562A1 (en) * | 2005-05-25 | 2007-05-31 | Transoral Pharmaceuticals, Inc. | Compositions and methods for treating middle-of-the-night insomnia |
| EP1948134A2 (de) * | 2005-10-17 | 2008-07-30 | Mallinckrodt, Inc. | Polymorph-transformation von zolpidem in einer tablettenmatrix |
| US20070098788A1 (en) * | 2005-10-28 | 2007-05-03 | Gore Subhash P | Non-benzodiazepine hypnotic compositions |
| ATE438381T1 (de) * | 2005-11-18 | 2009-08-15 | Synhton B V | Zolpidemtabletten |
| US7989207B2 (en) * | 2006-02-17 | 2011-08-02 | Tyco Healthcare Group Lp | Testing lumenectomy samples for markers of non-vascular diseases |
| PL2007752T3 (pl) | 2006-03-31 | 2011-02-28 | Janssen Pharmaceutica Nv | Benzoimidazol-2-ilopirymidyny i pirazyny jako modulatory receptora histaminowego H4 |
| US20080145425A1 (en) * | 2006-12-15 | 2008-06-19 | Pliva Research & Development Limited | Pharmaceutical composition of zolpidem |
| US9371311B2 (en) | 2008-06-30 | 2016-06-21 | Janssen Pharmaceutica Nv | Benzoimidazol-2-yl pyrimidine derivatives |
| US8555875B2 (en) | 2008-12-23 | 2013-10-15 | Map Pharmaceuticals, Inc. | Inhalation devices and related methods for administration of sedative hypnotic compounds |
| SMT202000084T1 (it) * | 2013-03-06 | 2020-03-13 | Janssen Pharmaceutica Nv | Modulatori benzoimidazol-2-il pirimidinici del recettore h4 dell'istamina |
| CN104610253B (zh) * | 2015-01-26 | 2016-11-16 | 郑州大学 | 2‑三氟甲基‑2‑羟基‑2‑(2‑芳基吡啶并[1,2‑α]咪唑)乙酸酯类化合物 |
| CN106432233B (zh) * | 2016-09-20 | 2018-08-14 | 华东理工大学 | N,N,6-三甲基-2-(4-甲基苯基)咪唑并[1,2-a]吡啶-3-乙酰胺的制备方法 |
| EP3611256A1 (de) * | 2018-08-14 | 2020-02-19 | Universität Heidelberg | Verwendung von imidazopyridinderivaten in der regenerativen medizin |
| CN116217565B (zh) * | 2021-12-03 | 2026-03-17 | 山东新时代药业有限公司 | 唑吡坦盐及其制备方法 |
| CN116283958B (zh) * | 2021-12-03 | 2026-02-24 | 山东新时代药业有限公司 | 唑吡坦共晶体及其制备方法 |
| CN116283957A (zh) * | 2021-12-03 | 2023-06-23 | 山东新时代药业有限公司 | 唑吡坦水合物及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2492382A1 (fr) * | 1980-10-22 | 1982-04-23 | Synthelabo | Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique |
| FR2600650B1 (fr) | 1986-06-27 | 1988-09-09 | Synthelabo | Procede de preparation d'imidazopyridines et composes intermediaires |
-
1999
- 1999-10-22 AT AT99203478T patent/ATE242241T1/de not_active IP Right Cessation
- 1999-10-22 SI SI9930383T patent/SI1038875T1/xx unknown
- 1999-10-22 EP EP99203478A patent/EP1038875B1/de not_active Expired - Lifetime
- 1999-10-22 DE DE69908546T patent/DE69908546T2/de not_active Expired - Fee Related
- 1999-10-22 PT PT99203478T patent/PT1038875E/pt unknown
- 1999-10-22 ES ES99203478T patent/ES2195510T3/es not_active Expired - Lifetime
- 1999-10-22 DK DK99203478T patent/DK1038875T3/da active
- 1999-11-26 US US09/449,974 patent/US6242460B1/en not_active Expired - Fee Related
-
2000
- 2000-02-25 US US09/512,789 patent/US6281360B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1038875A2 (de) | 2000-09-27 |
| US6281360B1 (en) | 2001-08-28 |
| US6242460B1 (en) | 2001-06-05 |
| DE69908546D1 (de) | 2003-07-10 |
| PT1038875E (pt) | 2003-10-31 |
| DE69908546T2 (de) | 2004-04-29 |
| SI1038875T1 (en) | 2003-12-31 |
| EP1038875A3 (de) | 2001-09-12 |
| ES2195510T3 (es) | 2003-12-01 |
| DK1038875T3 (da) | 2003-09-29 |
| EP1038875B1 (de) | 2003-06-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1038875 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |