ATE227774T1 - Milchsäurebakterielle supressor mutanten und ihre anwendung als selektive marker und als mässigmittel in milchsäurebakterien - Google Patents

Milchsäurebakterielle supressor mutanten und ihre anwendung als selektive marker und als mässigmittel in milchsäurebakterien

Info

Publication number
ATE227774T1
ATE227774T1 AT94929490T AT94929490T ATE227774T1 AT E227774 T1 ATE227774 T1 AT E227774T1 AT 94929490 T AT94929490 T AT 94929490T AT 94929490 T AT94929490 T AT 94929490T AT E227774 T1 ATE227774 T1 AT E227774T1
Authority
AT
Austria
Prior art keywords
lactic acid
mutants
moderants
supressor
application
Prior art date
Application number
AT94929490T
Other languages
English (en)
Inventor
Francoise Dickely
Eric Johansen
Dan Nilsson
Egon Bech Hansen
Per Stroeman
Original Assignee
Chr Hansen As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chr Hansen As filed Critical Chr Hansen As
Application granted granted Critical
Publication of ATE227774T1 publication Critical patent/ATE227774T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/68—Stabilisation of the vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT94929490T 1993-10-08 1994-10-07 Milchsäurebakterielle supressor mutanten und ihre anwendung als selektive marker und als mässigmittel in milchsäurebakterien ATE227774T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13339093A 1993-10-08 1993-10-08
US08/242,098 US5691185A (en) 1993-10-08 1994-05-13 Lactic acid bacterial suppressor mutants and their use as selective markers and as means of containment in lactic acid bacteria
PCT/DK1994/000376 WO1995010621A1 (en) 1993-10-08 1994-10-07 Lactic acid bacterial suppressor mutants and their use as selective markers and as means of containment in lactic acid bacteria

Publications (1)

Publication Number Publication Date
ATE227774T1 true ATE227774T1 (de) 2002-11-15

Family

ID=26831333

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94929490T ATE227774T1 (de) 1993-10-08 1994-10-07 Milchsäurebakterielle supressor mutanten und ihre anwendung als selektive marker und als mässigmittel in milchsäurebakterien

Country Status (10)

Country Link
US (2) US5691185A (de)
EP (1) EP0722503B1 (de)
AT (1) ATE227774T1 (de)
AU (1) AU684556B2 (de)
CA (1) CA2160166C (de)
DE (1) DE69431727T2 (de)
DK (1) DK0722503T3 (de)
ES (1) ES2185669T3 (de)
NZ (1) NZ274481A (de)
WO (1) WO1995010621A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7358083B1 (en) * 1998-04-21 2008-04-15 Chr. Hansen A/S Food-grade cloning vector and their use in lactic acid bacteria
EP1073757B1 (de) * 1998-04-21 2012-11-28 Chr. Hansen A/S Nahrungmittel-taugliche klonierungsvektoren und deren verwendung in milchsäurebakterien
FR2778921B1 (fr) * 1998-05-22 2001-05-11 Gervais Danone Sa Souches mutantes de lactobacillus bulgaricus depourvues d'activite beta-galactosidase
EP1102837B1 (de) 1998-07-03 2010-05-26 Chr. Hansen A/S Verfahren zur verhinderung von bakteriophageninfektion in bakterienkulturen
US7892585B1 (en) * 1998-07-03 2011-02-22 Chr Hansen A/S Method of preventing bacteriophage infection of bacterial cultures
US6787348B1 (en) * 1998-08-26 2004-09-07 Chr. Hansen Liquid starter cultures having improved storage stability and use thereof
IL130303A0 (en) 1999-06-03 2000-06-01 M G Novobiotech Ltd A bacterial strain processed plant extracts and probiotic compositions for human and veterinary use
US7780961B2 (en) 2001-05-03 2010-08-24 Actogenix N.V. Self-containing Lactococcus strain
US7101565B2 (en) 2002-02-05 2006-09-05 Corpak Medsystems, Inc. Probiotic/prebiotic composition and delivery method
ATE389415T1 (de) 2002-06-19 2008-04-15 Actogenix Nv Verfahren und mittel zur erhöhung der darmabsorption
WO2005052151A1 (en) * 2003-11-19 2005-06-09 Dow Global Technologies Inc. Improved protein expression systems
US8748126B2 (en) 2005-11-29 2014-06-10 Actogenix N.V. Induction of mucosal tolerance to antigens
EP1869983A1 (de) * 2006-06-23 2007-12-26 Chr. Hansen A/S Milchsäurebakterien mit niedriger Nachsäuerungsrate
JP2010516269A (ja) 2007-01-25 2010-05-20 アクトジェニックス・エヌブイ 抗原の粘膜送達による免疫疾患の治療
AU2010247938B2 (en) 2009-05-11 2016-02-18 Pelican Technology Holdings, Inc. Production of recombinant proteins utilizing non-antibiotic selection methods and the incorporation of non-natural amino acids therein
WO2016033088A1 (en) * 2014-08-25 2016-03-03 GeneWeave Biosciences, Inc. Non-replicative transduction particles and transduction particle-based reporter systems
US11008602B2 (en) 2017-12-20 2021-05-18 Roche Molecular Systems, Inc. Non-replicative transduction particles and transduction particle-based reporter systems
DK3584316T1 (da) 2018-06-20 2020-08-03 Eligo Bioscience Bakteriel leveringsvehikel, fremgangsmåde til fremstilling og anvendelser deraf
US12098372B2 (en) 2019-12-30 2024-09-24 Eligo Bioscience Microbiome modulation of a host by delivery of DNA payloads with minimized spread
US11746352B2 (en) 2019-12-30 2023-09-05 Eligo Bioscience Microbiome modulation of a host by delivery of DNA payloads with minimized spread
WO2022144382A1 (en) 2020-12-30 2022-07-07 Eligo Bioscience Chimeric receptor binding proteins resistant to proteolytic degradation
KR20240020271A (ko) 2021-05-12 2024-02-14 엘리고 바이오사이언스 생산 박테리아 세포 및 제조 방법에서 이의 용도

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4687737A (en) * 1982-11-12 1987-08-18 Massachusetts Institute Of Technology Mammalian suppressor genes
JPS6486875A (en) * 1987-09-29 1989-03-31 Hoechst Japan Plasmid vector containing streptomycin-sensitive gene
NL8801529A (nl) * 1988-06-15 1990-01-02 Nl Zuivelonderzoek Inst Werkwijze voor het selecteren en stabiel handhaven van recombinant dna in melkzuurbacterien.

Also Published As

Publication number Publication date
CA2160166A1 (en) 1995-04-20
ES2185669T3 (es) 2003-05-01
WO1995010621A1 (en) 1995-04-20
US5691185A (en) 1997-11-25
CA2160166C (en) 2003-05-20
EP0722503B1 (de) 2002-11-13
AU7852994A (en) 1995-05-04
NZ274481A (en) 1996-12-20
DK0722503T3 (da) 2003-02-24
AU684556B2 (en) 1997-12-18
EP0722503A1 (de) 1996-07-24
DE69431727T2 (de) 2003-08-14
US5866385A (en) 1999-02-02
DE69431727D1 (de) 2002-12-19

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