ATE227996T1 - Zusammensetzung und verfahren zur regulierung von zellproliferation und zelltod - Google Patents

Zusammensetzung und verfahren zur regulierung von zellproliferation und zelltod

Info

Publication number
ATE227996T1
ATE227996T1 AT98938555T AT98938555T ATE227996T1 AT E227996 T1 ATE227996 T1 AT E227996T1 AT 98938555 T AT98938555 T AT 98938555T AT 98938555 T AT98938555 T AT 98938555T AT E227996 T1 ATE227996 T1 AT E227996T1
Authority
AT
Austria
Prior art keywords
composition
cell
regulating
dna
cell proliferation
Prior art date
Application number
AT98938555T
Other languages
English (en)
Inventor
Nigel C Phillips
Mario C Fillion
Original Assignee
Bioniche Life Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioniche Life Sciences Inc filed Critical Bioniche Life Sciences Inc
Application granted granted Critical
Publication of ATE227996T1 publication Critical patent/ATE227996T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT98938555T 1997-08-05 1998-08-05 Zusammensetzung und verfahren zur regulierung von zellproliferation und zelltod ATE227996T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5477797P 1997-08-05 1997-08-05
US7506798P 1998-02-18 1998-02-18
US7511198P 1998-02-18 1998-02-18
US8631798P 1998-05-21 1998-05-21
PCT/CA1998/000744 WO1999007383A1 (en) 1997-08-05 1998-08-05 Composition and method for regulating cell proliferation and cell death

Publications (1)

Publication Number Publication Date
ATE227996T1 true ATE227996T1 (de) 2002-12-15

Family

ID=27489673

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98938555T ATE227996T1 (de) 1997-08-05 1998-08-05 Zusammensetzung und verfahren zur regulierung von zellproliferation und zelltod

Country Status (17)

Country Link
US (2) US6326357B1 (de)
EP (1) EP1003525B1 (de)
JP (2) JP4335435B2 (de)
KR (1) KR100533576B1 (de)
AT (1) ATE227996T1 (de)
AU (1) AU736450B2 (de)
BR (1) BR9815602A (de)
CA (1) CA2299548C (de)
DE (1) DE69809561T2 (de)
DK (1) DK1003525T3 (de)
ES (1) ES2187047T3 (de)
HU (1) HU227921B1 (de)
IL (3) IL134371A0 (de)
NO (1) NO322450B1 (de)
NZ (1) NZ502674A (de)
PT (1) PT1003525E (de)
WO (1) WO1999007383A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1003525E (pt) 1997-08-05 2003-03-31 Bioniche Life Sciences Inc Composicao e metodo para a regulacao da proliferacao e da morte celular
DE69829316T2 (de) * 1998-02-18 2006-04-13 Bioniche Life Sciences Inc., Belleville Behandlung des harnblasenkrebses durch mycobacterium phlei zellwand
DK1135161T3 (da) * 1998-12-04 2005-01-24 Bioniche Life Sciences Inc Kemoterapeutisk sammensætning og fremgangsmåde
WO2000033879A1 (en) * 1998-12-04 2000-06-15 Bioniche Life Sciences Inc. Method for the treatment of inflammation
US6809081B1 (en) * 1998-12-04 2004-10-26 Bioniche Life Sciences, Inc. Chemotherapeutic composition and method
PT1165106E (pt) * 1999-04-01 2005-10-31 Bioniche Life Sciences Inc Composicoes e metodo para induzir apoptose em celulas de cancro da prostata, por m-adn e mcc
US6794368B1 (en) 1999-04-01 2004-09-21 Bioniche Life Sciences Inc. Composition and method for inducing apoptosis in prostate cancer cells
US7314926B1 (en) 1999-04-08 2008-01-01 Antisoma Research Limited Antiproliferative activity of g-rich oligonucleotides and method of using same to bind to nucleolin
WO2001022979A1 (en) * 1999-09-29 2001-04-05 Bioniche Life Sciences Inc. Method to disrupt mitochondrial function
CZ20022372A3 (cs) * 1999-12-13 2002-11-13 Bioniche Life Sciences Inc. Terapeuticky pouľitelné syntetické oligonukleotidy
US7125858B2 (en) 1999-12-28 2006-10-24 Bioniche Life Sciences Inc. Hyaluronic acid in the treatment of cancer
US20030044352A1 (en) * 2001-04-24 2003-03-06 Phillips Nigel C. Method for evaluating the efficacy of treatment with bacterial DNA and bacterial cell walls
US6673566B1 (en) 2002-01-10 2004-01-06 The United States Of America As Represented By The Secretary Of Agriculture Diagnosis of pathogen infections through analysis of nitrite production by antigen stimulated leukocytes
JP2009544680A (ja) 2006-07-25 2009-12-17 リポクセン テクノロジーズ リミテッド ポリサッカライドによるタンパク質のｎ末端誘導体化
HUE052413T2 (hu) 2010-10-13 2021-04-28 Telesta Therapeutics Inc Bakteriális ribonukleinsav-sejtfalkészítmények és elõállítási és felhasználási módszereik

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3172815A (en) 1962-04-24 1965-03-09 Warner Lambert Pharmaceutical Method for preparing reticulo-endo-thelial system stimulant and stimulant thereof
US4152423A (en) 1971-11-19 1979-05-01 Agence Nationale De Valorisation De La Recherche (Anvar) Immunological agents
FR2160326B1 (de) 1971-11-19 1975-02-07 Anvar
CH602920A5 (de) 1973-02-23 1978-08-15 Wellcome Found
US3976544A (en) 1973-06-19 1976-08-24 The Agence Nationale De Valorisation De Le Recherche Water-soluble immunological adjuvants, in particular for vaccines, obtained from mycobacteria and related microorganisms and process for their extraction
FR2374042A1 (fr) 1976-06-04 1978-07-13 Merieux Inst Nouveau medicament immunostimulant et son procede de preparation
JPS54140710A (en) 1978-03-10 1979-11-01 Mitsui Toatsu Chem Inc Anti-tumor substance and its preparation
DE3011461C2 (de) 1980-03-25 1986-10-30 Dr. Madaus & Co, 5000 Köln Verwendung von Propionibakterien
US4520019A (en) 1982-04-29 1985-05-28 Ribi Immunochem Research, Inc. Stable composition and preparation thereof
US4579941A (en) 1982-08-13 1986-04-01 Mitsuitoatsu Chemicals, Inc. Thermally-denatured deoxyribonucleic acid MD-011 and antitumor agent
US4663306A (en) 1983-09-23 1987-05-05 Ribi Immunochem Research, Inc. Pyridine-soluble extract-refined detoxified endotoxin composition and use
GB8404280D0 (en) 1984-02-17 1984-03-21 Stanford J L Biological preparations
US4744984A (en) 1985-10-08 1988-05-17 Vetrepharm Research, Inc. Antiviral immunotherapeutic agent and preparation thereof
US4877611A (en) 1986-04-15 1989-10-31 Ribi Immunochem Research Inc. Vaccine containing tumor antigens and adjuvants
CN1102855C (zh) 1993-01-29 2003-03-12 维特里制药有限公司 免疫治疗组合物
PT1003525E (pt) 1997-08-05 2003-03-31 Bioniche Life Sciences Inc Composicao e metodo para a regulacao da proliferacao e da morte celular

Also Published As

Publication number Publication date
JP2001513504A (ja) 2001-09-04
JP4335435B2 (ja) 2009-09-30
EP1003525A1 (de) 2000-05-31
CA2299548A1 (en) 1999-02-18
DK1003525T3 (da) 2003-03-24
WO1999007383A1 (en) 1999-02-18
HUP0003012A2 (hu) 2000-12-28
WO1999007383B1 (en) 1999-03-25
NO322450B1 (no) 2006-10-09
US6326357B1 (en) 2001-12-04
BR9815602A (pt) 2001-12-11
NO20000576L (no) 2000-04-04
IL180924A0 (en) 2007-07-04
PT1003525E (pt) 2003-03-31
HUP0003012A3 (en) 2004-03-29
IL134371A0 (en) 2001-04-30
JP2008208140A (ja) 2008-09-11
AU736450B2 (en) 2001-07-26
IL134371A (en) 2007-07-24
IL180924A (en) 2010-11-30
DE69809561D1 (de) 2003-01-02
KR20010022643A (ko) 2001-03-26
EP1003525B1 (de) 2002-11-20
ES2187047T3 (es) 2003-05-16
HU227921B1 (hu) 2012-06-28
NO20000576D0 (no) 2000-02-04
DE69809561T2 (de) 2003-09-25
CA2299548C (en) 2009-12-29
KR100533576B1 (ko) 2005-12-05
NZ502674A (en) 2002-06-28
US6329347B1 (en) 2001-12-11
AU8723698A (en) 1999-03-01

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