ATE228003T1 - Verwendung von cntf (ciliary neurotrophic factor) rezeptoraktivatoren fur behandlung von fettleibigkeit - Google Patents

Verwendung von cntf (ciliary neurotrophic factor) rezeptoraktivatoren fur behandlung von fettleibigkeit

Info

Publication number
ATE228003T1
ATE228003T1 AT97946043T AT97946043T ATE228003T1 AT E228003 T1 ATE228003 T1 AT E228003T1 AT 97946043 T AT97946043 T AT 97946043T AT 97946043 T AT97946043 T AT 97946043T AT E228003 T1 ATE228003 T1 AT E228003T1
Authority
AT
Austria
Prior art keywords
obesity
cntf
treatment
neurotrophic factor
ciliary neurotrophic
Prior art date
Application number
AT97946043T
Other languages
English (en)
Inventor
Gennaro Ciliberto
Patrizia Costa
Giacomo Paonessa
Domenico Lazzaro
Isabelle Gloaguen
Marco Annalise Di
Martis Anna De
Ralph Laufer
Riccardo Cortese
Original Assignee
Angeletti P Ist Richerche Bio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeletti P Ist Richerche Bio filed Critical Angeletti P Ist Richerche Bio
Application granted granted Critical
Publication of ATE228003T1 publication Critical patent/ATE228003T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2264—Obesity-gene products, e.g. leptin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
AT97946043T 1996-11-19 1997-11-18 Verwendung von cntf (ciliary neurotrophic factor) rezeptoraktivatoren fur behandlung von fettleibigkeit ATE228003T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96RM000790A IT1288388B1 (it) 1996-11-19 1996-11-19 Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia
PCT/IT1997/000283 WO1998022128A1 (en) 1996-11-19 1997-11-18 Use of cntf (ciliary neurotrophic factor) receptor activators for the treatment of obesity

Publications (1)

Publication Number Publication Date
ATE228003T1 true ATE228003T1 (de) 2002-12-15

Family

ID=11404538

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97946043T ATE228003T1 (de) 1996-11-19 1997-11-18 Verwendung von cntf (ciliary neurotrophic factor) rezeptoraktivatoren fur behandlung von fettleibigkeit

Country Status (14)

Country Link
US (2) US6565869B1 (de)
EP (1) EP0946189B1 (de)
JP (1) JP4067127B2 (de)
CN (2) CN101703761B (de)
AT (1) ATE228003T1 (de)
AU (1) AU727174B2 (de)
CA (1) CA2271781C (de)
DE (1) DE69717308T2 (de)
DK (1) DK0946189T3 (de)
ES (1) ES2187830T3 (de)
IL (2) IL129968A0 (de)
IT (1) IT1288388B1 (de)
PT (1) PT946189E (de)
WO (1) WO1998022128A1 (de)

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WO2018128745A1 (en) * 2017-01-06 2018-07-12 The Board Of Trustees Of The Leland Stanford Junior University Ciliary neurotrophic factor receptor ligands and methods of using the same
KR20200100089A (ko) 2017-12-18 2020-08-25 리제너론 파마슈티칼스 인코포레이티드 렙틴 수용체 및/또는 gp130에 결합하는 이중 특이적 항원 결합 분자 및 이의 사용 방법
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CA3248332A1 (en) * 2018-06-19 2025-11-29 Cella Therapeutics, Llc Drug delivery systems comprising a neurotrophic agent, an apoptosis signaling fragment inhibitor (fas) or fas ligand (fasl) inhibitor, a tumor necrosis factor-alpha (tnf-alpha) or tnf receptor inhibitor, a mitochondrial peptide, an oligonucleotide, a chemokine inhibitor, or a cysteine-aspartic protease
JP2021531327A (ja) * 2018-06-19 2021-11-18 セラ セラピューティクス エルエルシー 眼圧降下剤、ｃｎｐ化合物、ｎｒｐ−ｂ化合物、ｔｉｅ−２アゴニスト、または神経栄養剤を含む、緑内障または高眼圧症を治療するための徐放性薬剤送達系
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Also Published As

Publication number Publication date
WO1998022128A1 (en) 1998-05-28
JP2000511561A (ja) 2000-09-05
DE69717308T2 (de) 2003-07-10
JP4067127B2 (ja) 2008-03-26
CN101703761A (zh) 2010-05-12
AU727174B2 (en) 2000-12-07
IL129968A (en) 2005-11-20
IT1288388B1 (it) 1998-09-22
DK0946189T3 (da) 2002-12-16
IL129968A0 (en) 2000-02-29
CN102145163A (zh) 2011-08-10
US20030176346A1 (en) 2003-09-18
CN102145163B (zh) 2013-09-18
ITRM960790A1 (it) 1998-05-19
EP0946189A1 (de) 1999-10-06
CA2271781A1 (en) 1998-05-28
ITRM960790A0 (it) 1996-11-19
CA2271781C (en) 2002-11-12
US6565869B1 (en) 2003-05-20
CN101703761B (zh) 2013-11-20
AU5134498A (en) 1998-06-10
ES2187830T3 (es) 2003-06-16
EP0946189B1 (de) 2002-11-20
US6960558B2 (en) 2005-11-01
DE69717308D1 (de) 2003-01-02
PT946189E (pt) 2003-02-28

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