ATE229078T1 - Methode zur synthese von amino-deoxy- disacchariden und amino-deoxy-oligosacchariden - Google Patents

Methode zur synthese von amino-deoxy- disacchariden und amino-deoxy-oligosacchariden

Info

Publication number
ATE229078T1
ATE229078T1 AT94916464T AT94916464T ATE229078T1 AT E229078 T1 ATE229078 T1 AT E229078T1 AT 94916464 T AT94916464 T AT 94916464T AT 94916464 T AT94916464 T AT 94916464T AT E229078 T1 ATE229078 T1 AT E229078T1
Authority
AT
Austria
Prior art keywords
amino
deoxy
synthesis
disaccharides
oligosaccharides
Prior art date
Application number
AT94916464T
Other languages
English (en)
Inventor
Kurt G I Nilsson
Original Assignee
Bioflexin Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioflexin Ab filed Critical Bioflexin Ab
Application granted granted Critical
Publication of ATE229078T1 publication Critical patent/ATE229078T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

Landscapes

  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT94916464T 1993-05-14 1994-05-17 Methode zur synthese von amino-deoxy- disacchariden und amino-deoxy-oligosacchariden ATE229078T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9301677A SE9301677L (sv) 1993-05-14 1993-05-14 Syntesmetod
PCT/SE1994/000461 WO1994029477A1 (en) 1993-05-14 1994-05-17 Method for the synthesis of amino-deoxy-disaccharides and amino-deoxy-oligosaccharides

Publications (1)

Publication Number Publication Date
ATE229078T1 true ATE229078T1 (de) 2002-12-15

Family

ID=20389953

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94916464T ATE229078T1 (de) 1993-05-14 1994-05-17 Methode zur synthese von amino-deoxy- disacchariden und amino-deoxy-oligosacchariden

Country Status (9)

Country Link
US (1) US5856143A (de)
EP (1) EP0698114B1 (de)
JP (1) JP3723208B2 (de)
AT (1) ATE229078T1 (de)
CZ (1) CZ294859B6 (de)
DE (1) DE69431839T2 (de)
SE (1) SE9301677L (de)
SK (1) SK283138B6 (de)
WO (1) WO1994029477A1 (de)

Families Citing this family (36)

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SE9301270D0 (sv) 1993-04-19 1993-04-17 Biosensor
SE9400034D0 (sv) 1994-01-06 1994-01-06 Glycorex Ab Laktosaminderivat
US6284494B1 (en) 1995-12-12 2001-09-04 The University Of British Columbia Methods and compositions for synthesis of oligosaccharides using mutant glycosidase enzymes
US5716812A (en) * 1995-12-12 1998-02-10 The University Of British Columbia Methods and compositions for synthesis of oligosaccharides, and the products formed thereby
EP0886639B1 (de) * 1996-01-30 2008-05-28 GlycoMimetics, Inc. SIALYL-LEWISa UND SIALYL-LEWISx EPITOPE ANALOGE
ATE357452T1 (de) 1996-01-30 2007-04-15 Glycomimetics Inc Sialyl-lewisa und sialyl lewisx epitop-analoge
US7014049B2 (en) 1996-12-23 2006-03-21 Glycorex Transplantation Ab Device for bio-affinity material
DE19812162A1 (de) * 1998-03-20 1999-09-30 Forschungszentrum Juelich Gmbh Nucleotidaktivierte Di- und Oligosaccharide sowie Verfahren zu deren Herstellung I
DE19812156A1 (de) * 1998-03-20 1999-09-30 Forschungszentrum Juelich Gmbh Nucleotidaktivierte Di- und Oligosaccharide sowie Verfahren zu deren Herstellung II
AU2136201A (en) * 1999-12-10 2001-06-18 National Research Council Of Canada Method for the synthesis of sialylated oligosaccharide donors
EP1438387A4 (de) * 2001-09-14 2004-10-13 Momenta Pharmaceuticals Inc Verfahren zur herstellung von glycomolekülen mit verstärkten aktivitäten und verwendungen davon
WO2003097658A2 (en) 2002-05-16 2003-11-27 Glycomimetics, Inc. Compounds and methods for inhibiting selectin-mediated function
EP1763533B1 (de) 2003-11-19 2008-01-09 GlycoMimetics, Inc. Spezifischer antagonist sowohl für e- als auch p-selektine
CN101291946B (zh) 2005-08-09 2011-06-29 糖模拟物有限公司 对来自假单胞菌的pa-il凝集素、pa-iil凝集素或其两者的糖模拟物抑制剂
PL2264043T3 (pl) 2005-09-02 2018-04-30 Glycomimetics, Inc. Heterobifunkcyjne inhibitory pan-selektyny
WO2009126556A1 (en) 2008-04-08 2009-10-15 Glycomimetics, Inc. Pan-selectin inhibitor with enhanced pharmacokinetic activity
WO2011127322A1 (en) 2010-04-07 2011-10-13 Momenta Pharmaceuticals, Inc. High mannose glycans
US8921328B2 (en) 2010-09-14 2014-12-30 Glycomimetics, Inc. E-selectin antagonists
EP2686671A4 (de) 2011-03-12 2015-06-24 Momenta Pharmaceuticals Inc N-acetylhexosamin-haltige n-glykane in glycoproteinprodukten
KR102055958B1 (ko) 2011-12-22 2019-12-13 글리코미메틱스, 인크. E-셀렉틴 길항제 화합물, 조성물, 및 이용 방법
WO2013181575A2 (en) 2012-06-01 2013-12-05 Momenta Pharmaceuticals, Inc. Methods related to denosumab
EP2877589B1 (de) 2012-07-26 2024-03-06 Momenta Pharmaceuticals, Inc. Glykoproteine mit entzündungshemmenden eigenschaften
US9867841B2 (en) 2012-12-07 2018-01-16 Glycomimetics, Inc. Compounds, compositions and methods using E-selectin antagonists for mobilization of hematopoietic cells
US10450361B2 (en) 2013-03-15 2019-10-22 Momenta Pharmaceuticals, Inc. Methods related to CTLA4-Fc fusion proteins
WO2014186310A1 (en) 2013-05-13 2014-11-20 Momenta Pharmaceuticals, Inc. Methods for the treatment of neurodegeneration
WO2015057622A1 (en) 2013-10-16 2015-04-23 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins
JP6689854B2 (ja) 2014-12-03 2020-04-28 グリコミメティクス， インコーポレイテッド Ｅ−セレクチンおよびｃｘｃｒ４ケモカイン受容体のヘテロ二官能性阻害剤
JP2019502727A (ja) 2016-01-22 2019-01-31 グリコミメティクス， インコーポレイテッド Ｐａ−ｉｌおよび／またはｐａ−ｉｉｌレクチンの糖模倣体阻害剤
WO2017151708A1 (en) 2016-03-02 2017-09-08 Glycomimetics, Inc. Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin
US11433086B2 (en) 2016-08-08 2022-09-06 Glycomimetics, Inc. Combination of T-cell checkpoint inhibitors with inhibitors of e-selectin or CXCR4, or with heterobifunctional inhibitors of both E-selectin and CXCR4
AU2017341065B2 (en) 2016-10-07 2023-04-06 Crescent Biopharma, Inc. Highly potent multimeric E-selectin antagonists
EP3596096A1 (de) 2017-03-15 2020-01-22 GlycoMimetics, Inc. Galactopyranosyl-cyclohexyl-derivate als e-selectin-antagonisten
JP7275131B2 (ja) 2017-11-30 2023-05-17 グリコミメティクス， インコーポレイテッド 骨髄浸潤リンパ球を動員する方法、およびその使用
KR20200104889A (ko) 2017-12-29 2020-09-04 글리코미메틱스, 인크. E-셀렉틴 및 갈렉틴-3의 이종이기능성 억제제
KR20200128025A (ko) 2018-03-05 2020-11-11 글리코미메틱스, 인크. 급성 골수성 백혈병 및 관련 병태의 치료 방법
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415665A (en) * 1980-12-12 1983-11-15 Pharmacia Fine Chemicals Ab Method of covalently binding biologically active organic substances to polymeric substances
SE451849B (sv) * 1985-12-11 1987-11-02 Svenska Sockerfabriks Ab Sett att syntetisera glykosidiska bindningar samt anvendning av pa detta sett erhallna produkter
ZA881430B (de) * 1988-03-02 1988-10-28
SE466403B (sv) * 1988-03-24 1992-02-10 Kurt G I Nilsson Saett att syntetisera oligosackarider
SE466521B (sv) * 1988-10-03 1992-02-24 Kurt G I Nilsson Reagens vid analys bestaaende av ett enzym och en annan ligand, vilka aer kovalent bundna till en vattenoloeslig partikel med en diameter paa mindre aen 500 aa
SE465516B (sv) * 1989-08-18 1991-09-23 Kurt G I Nilsson Saett att framstaella en oligosackaridfoerening varvid glykosidas fraan en mollusk anvaendes
JPH04353521A (ja) * 1991-05-30 1992-12-08 Toray Dow Corning Silicone Co Ltd オルガノポリシルセスキオキサンおよびその製造方法
EP0589951A1 (de) * 1991-06-10 1994-04-06 Glycomed Incorporated Modifizierte Sialyl Lewis X-Verbindungen
SE9102292L (sv) * 1991-08-06 1993-02-07 Kurt G I Nilsson Enzymatisk metod
US5326867A (en) * 1992-07-16 1994-07-05 Bristol-Myers Squibb Company Pradimic acids, amides, and pradimicin derivatives

Also Published As

Publication number Publication date
SK283138B6 (sk) 2003-03-04
SK145095A3 (en) 1996-06-05
JP3723208B2 (ja) 2005-12-07
DE69431839T2 (de) 2003-04-10
DE69431839D1 (de) 2003-01-16
EP0698114B1 (de) 2002-12-04
CZ294859B6 (cs) 2005-04-13
JP2002502223A (ja) 2002-01-22
CZ301895A3 (en) 1996-03-13
US5856143A (en) 1999-01-05
SE9301677L (sv) 1994-11-18
WO1994029477A1 (en) 1994-12-22
EP0698114A1 (de) 1996-02-28
SE9301677D0 (sv) 1993-05-14

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