ATE229078T1 - Methode zur synthese von amino-deoxy- disacchariden und amino-deoxy-oligosacchariden - Google Patents

Methode zur synthese von amino-deoxy- disacchariden und amino-deoxy-oligosacchariden

Info

Publication number
ATE229078T1
ATE229078T1 AT94916464T AT94916464T ATE229078T1 AT E229078 T1 ATE229078 T1 AT E229078T1 AT 94916464 T AT94916464 T AT 94916464T AT 94916464 T AT94916464 T AT 94916464T AT E229078 T1 ATE229078 T1 AT E229078T1
Authority
AT
Austria
Prior art keywords
amino
deoxy
synthesis
disaccharides
oligosaccharides
Prior art date
Application number
AT94916464T
Other languages
English (en)
Inventor
Kurt G I Nilsson
Original Assignee
Bioflexin Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioflexin Ab filed Critical Bioflexin Ab
Application granted granted Critical
Publication of ATE229078T1 publication Critical patent/ATE229078T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

Landscapes

  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT94916464T 1993-05-14 1994-05-17 Methode zur synthese von amino-deoxy- disacchariden und amino-deoxy-oligosacchariden ATE229078T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9301677A SE9301677L (sv) 1993-05-14 1993-05-14 Syntesmetod
PCT/SE1994/000461 WO1994029477A1 (en) 1993-05-14 1994-05-17 Method for the synthesis of amino-deoxy-disaccharides and amino-deoxy-oligosaccharides

Publications (1)

Publication Number Publication Date
ATE229078T1 true ATE229078T1 (de) 2002-12-15

Family

ID=20389953

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94916464T ATE229078T1 (de) 1993-05-14 1994-05-17 Methode zur synthese von amino-deoxy- disacchariden und amino-deoxy-oligosacchariden

Country Status (9)

Country Link
US (1) US5856143A (de)
EP (1) EP0698114B1 (de)
JP (1) JP3723208B2 (de)
AT (1) ATE229078T1 (de)
CZ (1) CZ294859B6 (de)
DE (1) DE69431839T2 (de)
SE (1) SE9301677L (de)
SK (1) SK283138B6 (de)
WO (1) WO1994029477A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9301270D0 (sv) 1993-04-19 1993-04-17 Biosensor
SE9400034D0 (sv) * 1994-01-06 1994-01-06 Glycorex Ab Laktosaminderivat
US5716812A (en) * 1995-12-12 1998-02-10 The University Of British Columbia Methods and compositions for synthesis of oligosaccharides, and the products formed thereby
US6284494B1 (en) 1995-12-12 2001-09-04 The University Of British Columbia Methods and compositions for synthesis of oligosaccharides using mutant glycosidase enzymes
DE69737496D1 (de) 1996-01-30 2007-05-03 Glycomimetics Inc SIALYL-LEWISa UND SIALYL LEWISx EPITOP-ANALOGE
US6187754B1 (en) * 1996-01-30 2001-02-13 Glycotech Corp. Sialyl-Lewisa and sialyl-Lewisx epitode analogues
US7014049B2 (en) 1996-12-23 2006-03-21 Glycorex Transplantation Ab Device for bio-affinity material
DE19812156A1 (de) * 1998-03-20 1999-09-30 Forschungszentrum Juelich Gmbh Nucleotidaktivierte Di- und Oligosaccharide sowie Verfahren zu deren Herstellung II
DE19812162A1 (de) * 1998-03-20 1999-09-30 Forschungszentrum Juelich Gmbh Nucleotidaktivierte Di- und Oligosaccharide sowie Verfahren zu deren Herstellung I
WO2001042264A1 (en) * 1999-12-10 2001-06-14 National Research Council Of Canada Method for the synthesis of sialylated oligosaccharide donors
EP1438387A4 (de) * 2001-09-14 2004-10-13 Momenta Pharmaceuticals Inc Verfahren zur herstellung von glycomolekülen mit verstärkten aktivitäten und verwendungen davon
JP5183010B2 (ja) 2002-05-16 2013-04-17 グリコミメティクス， インコーポレイテッド セレクチンによって媒介される機能を阻害するための化合物および方法
DE602004011272T2 (de) 2003-11-19 2008-12-24 Glycomimetics, Inc. Spezifischer antagonist sowohl für e- als auch p-selektine
WO2007021721A2 (en) 2005-08-09 2007-02-22 Glycomimetics, Inc. Glycomimetic inhibitors of the pa-il lectin, pa-iil lectin or both the lectins from pseudomonas
SI2264043T1 (en) 2005-09-02 2018-01-31 Glycomimetics, Inc. HETEROBIFUNCTIONAL PAN-SELECTINE INHIBITORS
US8895510B2 (en) 2008-04-08 2014-11-25 Glycomimetics, Inc. Pan-selectin inhibitor with enhanced pharmacokinetic activity
AU2011237442A1 (en) 2010-04-07 2012-10-18 Momenta Pharmaceuticals, Inc. High mannose glycans
US8921328B2 (en) 2010-09-14 2014-12-30 Glycomimetics, Inc. E-selectin antagonists
WO2012125553A2 (en) 2011-03-12 2012-09-20 Momenta Pharmaceuticals, Inc. N-acetylhexosamine-containing n-glycans in glycoprotein products
EP2794626B3 (de) 2011-12-22 2020-08-05 GlycoMimetics, Inc. E-selectin-antagonistenverbindungen
US9695244B2 (en) 2012-06-01 2017-07-04 Momenta Pharmaceuticals, Inc. Methods related to denosumab
WO2014018747A2 (en) 2012-07-26 2014-01-30 Momenta Pharmaceuticals, Inc. Glycoproteins with anti-inflammatory properties
HUE038423T2 (hu) 2012-12-07 2018-10-29 Glycomimetics Inc E-szelektin antagonistákat felhasználó vegyületek, készítmények és eljárások vérképzõ sejtek mobilizációjára
US10450361B2 (en) 2013-03-15 2019-10-22 Momenta Pharmaceuticals, Inc. Methods related to CTLA4-Fc fusion proteins
ES2708759T3 (es) 2013-05-13 2019-04-11 Momenta Pharmaceuticals Inc Procedimientos para el tratamiento de la neurodegeneración
EP3058084A4 (de) 2013-10-16 2017-07-05 Momenta Pharmaceuticals, Inc. Sialylierte glycoproteine
CN107108679B (zh) 2014-12-03 2020-10-23 糖模拟物有限公司 E-选择蛋白和cxcr4趋化因子受体的异双官能抑制剂
WO2017127422A1 (en) 2016-01-22 2017-07-27 Glycomimetics, Inc. Glycomimetic inhibitors of pa-il and pa-iil lectins
US11291678B2 (en) 2016-03-02 2022-04-05 Glycomimetics, Inc Methods for the treatment and/or prevention of cardiovascular disease by inhibition of E-selectin
US11433086B2 (en) 2016-08-08 2022-09-06 Glycomimetics, Inc. Combination of T-cell checkpoint inhibitors with inhibitors of e-selectin or CXCR4, or with heterobifunctional inhibitors of both E-selectin and CXCR4
BR112019006642A2 (pt) 2016-10-07 2019-07-02 Glycomimetics Inc antagonistas multiméricos de e-selectina altamente potentes
CA3054605A1 (en) 2017-03-15 2018-09-20 Glycomimetics, Inc. Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists
EP3717013A1 (de) 2017-11-30 2020-10-07 GlycoMimetics, Inc. Verfahren zur mobilisierung von knochenmarkinfiltrierenden lymphozyten und deren verwendung
US11548908B2 (en) 2017-12-29 2023-01-10 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3
AU2019230013A1 (en) 2018-03-05 2020-09-10 Glycomimetics, Inc. Methods for treating acute myeloid leukemia and related conditions
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415665A (en) * 1980-12-12 1983-11-15 Pharmacia Fine Chemicals Ab Method of covalently binding biologically active organic substances to polymeric substances
SE451849B (sv) * 1985-12-11 1987-11-02 Svenska Sockerfabriks Ab Sett att syntetisera glykosidiska bindningar samt anvendning av pa detta sett erhallna produkter
ZA881430B (de) * 1988-03-02 1988-10-28
SE466403B (sv) * 1988-03-24 1992-02-10 Kurt G I Nilsson Saett att syntetisera oligosackarider
SE466521B (sv) * 1988-10-03 1992-02-24 Kurt G I Nilsson Reagens vid analys bestaaende av ett enzym och en annan ligand, vilka aer kovalent bundna till en vattenoloeslig partikel med en diameter paa mindre aen 500 aa
SE465516B (sv) * 1989-08-18 1991-09-23 Kurt G I Nilsson Saett att framstaella en oligosackaridfoerening varvid glykosidas fraan en mollusk anvaendes
JPH04353521A (ja) * 1991-05-30 1992-12-08 Toray Dow Corning Silicone Co Ltd オルガノポリシルセスキオキサンおよびその製造方法
EP0589951A1 (de) * 1991-06-10 1994-04-06 Glycomed Incorporated Modifizierte Sialyl Lewis X-Verbindungen
SE9102292L (sv) * 1991-08-06 1993-02-07 Kurt G I Nilsson Enzymatisk metod
US5326867A (en) * 1992-07-16 1994-07-05 Bristol-Myers Squibb Company Pradimic acids, amides, and pradimicin derivatives

Also Published As

Publication number Publication date
DE69431839T2 (de) 2003-04-10
CZ294859B6 (cs) 2005-04-13
DE69431839D1 (de) 2003-01-16
WO1994029477A1 (en) 1994-12-22
EP0698114A1 (de) 1996-02-28
SE9301677D0 (sv) 1993-05-14
EP0698114B1 (de) 2002-12-04
JP2002502223A (ja) 2002-01-22
US5856143A (en) 1999-01-05
SE9301677L (sv) 1994-11-18
SK283138B6 (sk) 2003-03-04
JP3723208B2 (ja) 2005-12-07
CZ301895A3 (en) 1996-03-13
SK145095A3 (en) 1996-06-05

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