ATE229078T1 - Methode zur synthese von amino-deoxy- disacchariden und amino-deoxy-oligosacchariden - Google Patents

Methode zur synthese von amino-deoxy- disacchariden und amino-deoxy-oligosacchariden

Info

Publication number
ATE229078T1
ATE229078T1 AT94916464T AT94916464T ATE229078T1 AT E229078 T1 ATE229078 T1 AT E229078T1 AT 94916464 T AT94916464 T AT 94916464T AT 94916464 T AT94916464 T AT 94916464T AT E229078 T1 ATE229078 T1 AT E229078T1
Authority
AT
Austria
Prior art keywords
amino
deoxy
synthesis
disaccharides
oligosaccharides
Prior art date
Application number
AT94916464T
Other languages
English (en)
Inventor
Kurt G I Nilsson
Original Assignee
Bioflexin Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioflexin Ab filed Critical Bioflexin Ab
Application granted granted Critical
Publication of ATE229078T1 publication Critical patent/ATE229078T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

Landscapes

  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT94916464T 1993-05-14 1994-05-17 Methode zur synthese von amino-deoxy- disacchariden und amino-deoxy-oligosacchariden ATE229078T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9301677A SE9301677L (sv) 1993-05-14 1993-05-14 Syntesmetod
PCT/SE1994/000461 WO1994029477A1 (en) 1993-05-14 1994-05-17 Method for the synthesis of amino-deoxy-disaccharides and amino-deoxy-oligosaccharides

Publications (1)

Publication Number Publication Date
ATE229078T1 true ATE229078T1 (de) 2002-12-15

Family

ID=20389953

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94916464T ATE229078T1 (de) 1993-05-14 1994-05-17 Methode zur synthese von amino-deoxy- disacchariden und amino-deoxy-oligosacchariden

Country Status (9)

Country Link
US (1) US5856143A (de)
EP (1) EP0698114B1 (de)
JP (1) JP3723208B2 (de)
AT (1) ATE229078T1 (de)
CZ (1) CZ294859B6 (de)
DE (1) DE69431839T2 (de)
SE (1) SE9301677L (de)
SK (1) SK283138B6 (de)
WO (1) WO1994029477A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9301270D0 (sv) 1993-04-19 1993-04-17 Biosensor
SE9400034D0 (sv) * 1994-01-06 1994-01-06 Glycorex Ab Laktosaminderivat
US5716812A (en) * 1995-12-12 1998-02-10 The University Of British Columbia Methods and compositions for synthesis of oligosaccharides, and the products formed thereby
US6284494B1 (en) 1995-12-12 2001-09-04 The University Of British Columbia Methods and compositions for synthesis of oligosaccharides using mutant glycosidase enzymes
US6187754B1 (en) * 1996-01-30 2001-02-13 Glycotech Corp. Sialyl-Lewisa and sialyl-Lewisx epitode analogues
US6169077B1 (en) 1996-01-30 2001-01-02 Glycotech Corp. Sialyl-Lewisa and sialyl-Lewisx epitope analogues
US7014049B2 (en) 1996-12-23 2006-03-21 Glycorex Transplantation Ab Device for bio-affinity material
DE19812162A1 (de) * 1998-03-20 1999-09-30 Forschungszentrum Juelich Gmbh Nucleotidaktivierte Di- und Oligosaccharide sowie Verfahren zu deren Herstellung I
DE19812156A1 (de) * 1998-03-20 1999-09-30 Forschungszentrum Juelich Gmbh Nucleotidaktivierte Di- und Oligosaccharide sowie Verfahren zu deren Herstellung II
AU2136201A (en) * 1999-12-10 2001-06-18 National Research Council Of Canada Method for the synthesis of sialylated oligosaccharide donors
WO2003025133A2 (en) * 2001-09-14 2003-03-27 Mimeon, Inc. Methods of making glycolmolecules with enhanced activities and uses thereof
AU2003249641B2 (en) 2002-05-16 2009-08-20 Glycomimetics, Inc. Compounds and methods for inhibiting selectin-mediated function
US7361644B2 (en) 2003-11-19 2008-04-22 Glycomimetics, Inc. Specific antagonist for both E- and P-selectins
JP5175190B2 (ja) 2005-08-09 2013-04-03 グリコミメティクス， インコーポレイテッド シュードモナス由来のｐａ−ｉｌレクチン、ｐａ−ｉｉｌレクチンまたは両方のレクチンのグリコミメティック阻害剤
US7728117B2 (en) 2005-09-02 2010-06-01 Glycomimetics, Inc. Heterobifunctional pan-selectin inhibitors
WO2009126556A1 (en) 2008-04-08 2009-10-15 Glycomimetics, Inc. Pan-selectin inhibitor with enhanced pharmacokinetic activity
CA2794697A1 (en) 2010-04-07 2011-10-13 Momenta Pharmaceuticals, Inc. High mannose glycans
US8921328B2 (en) 2010-09-14 2014-12-30 Glycomimetics, Inc. E-selectin antagonists
US9170249B2 (en) 2011-03-12 2015-10-27 Momenta Pharmaceuticals, Inc. N-acetylhexosamine-containing N-glycans in glycoprotein products
SI2794626T1 (en) 2011-12-22 2018-02-28 Glycomimetics, Inc. E-SELECTINE ANTAGONIST COMPOUNDS
EP2856159A4 (de) 2012-06-01 2016-04-13 Momenta Pharmaceuticals Inc Verfahren im zusammenhang mit denosumab
EP2877589B1 (de) 2012-07-26 2024-03-06 Momenta Pharmaceuticals, Inc. Glykoproteine mit entzündungshemmenden eigenschaften
LT2928476T (lt) 2012-12-07 2018-05-25 Glycomimetics, Inc. Junginiai, kompozicijos ir būdai, naudojant e-selektino antagonistus, hemopoetinių ląstelių mobilizacijai
EP2855533A4 (de) 2013-03-15 2015-11-25 Momenta Pharmaceuticals Inc Verfahren in zusammenhang mit ctla4-fc-fusionsproteinen
US10464996B2 (en) 2013-05-13 2019-11-05 Momenta Pharmaceuticals, Inc. Methods for the treatment of neurodegeneration
WO2015057622A1 (en) 2013-10-16 2015-04-23 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins
HUE045542T2 (hu) 2014-12-03 2019-12-30 Glycomimetics Inc E-szelektinek és CXCR4 kemokin receptorok heterobifunkcionális inhibitorai
WO2017127422A1 (en) 2016-01-22 2017-07-27 Glycomimetics, Inc. Glycomimetic inhibitors of pa-il and pa-iil lectins
WO2017151708A1 (en) 2016-03-02 2017-09-08 Glycomimetics, Inc. Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin
EP3497131B1 (de) 2016-08-08 2022-03-09 GlycoMimetics, Inc. Kombination von t-zell-checkpoint-inhibitoren mit e-selectin- oder cxcr4-inhibitoren oder mit heterobifunktionellen e-selectin- wie auch cxcr4-inhibitoren
CA3037850A1 (en) 2016-10-07 2018-04-12 Glycomimetics, Inc. Highly potent multimeric e-selectin antagonists
CA3054605A1 (en) 2017-03-15 2018-09-20 Glycomimetics, Inc. Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists
EP3717013A1 (de) 2017-11-30 2020-10-07 GlycoMimetics, Inc. Verfahren zur mobilisierung von knochenmarkinfiltrierenden lymphozyten und deren verwendung
EP3732186A1 (de) 2017-12-29 2020-11-04 GlycoMimetics, Inc. Heterobifunktionale inhibitoren von e-selektin und galectin-3
US11707474B2 (en) 2018-03-05 2023-07-25 Glycomimetics, Inc. Methods for treating acute myeloid leukemia and related conditions
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415665A (en) * 1980-12-12 1983-11-15 Pharmacia Fine Chemicals Ab Method of covalently binding biologically active organic substances to polymeric substances
SE451849B (sv) * 1985-12-11 1987-11-02 Svenska Sockerfabriks Ab Sett att syntetisera glykosidiska bindningar samt anvendning av pa detta sett erhallna produkter
ZA881430B (de) * 1988-03-02 1988-10-28
SE466403B (sv) * 1988-03-24 1992-02-10 Kurt G I Nilsson Saett att syntetisera oligosackarider
SE466521B (sv) * 1988-10-03 1992-02-24 Kurt G I Nilsson Reagens vid analys bestaaende av ett enzym och en annan ligand, vilka aer kovalent bundna till en vattenoloeslig partikel med en diameter paa mindre aen 500 aa
SE465516B (sv) * 1989-08-18 1991-09-23 Kurt G I Nilsson Saett att framstaella en oligosackaridfoerening varvid glykosidas fraan en mollusk anvaendes
JPH04353521A (ja) * 1991-05-30 1992-12-08 Toray Dow Corning Silicone Co Ltd オルガノポリシルセスキオキサンおよびその製造方法
CA2110797C (en) * 1991-06-10 2001-02-20 Andre P. Venot Modified sialyl lewis x compounds
SE9102292L (sv) * 1991-08-06 1993-02-07 Kurt G I Nilsson Enzymatisk metod
US5326867A (en) * 1992-07-16 1994-07-05 Bristol-Myers Squibb Company Pradimic acids, amides, and pradimicin derivatives

Also Published As

Publication number Publication date
EP0698114A1 (de) 1996-02-28
CZ294859B6 (cs) 2005-04-13
DE69431839T2 (de) 2003-04-10
US5856143A (en) 1999-01-05
JP3723208B2 (ja) 2005-12-07
JP2002502223A (ja) 2002-01-22
WO1994029477A1 (en) 1994-12-22
EP0698114B1 (de) 2002-12-04
SK145095A3 (en) 1996-06-05
SE9301677D0 (sv) 1993-05-14
SK283138B6 (sk) 2003-03-04
SE9301677L (sv) 1994-11-18
CZ301895A3 (en) 1996-03-13
DE69431839D1 (de) 2003-01-16

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