ATE229535T1 - Benzo(6)thiophen-verbindungen, zwischenprodukte, zusammensetzungen und verfahren dafür - Google Patents

Benzo(6)thiophen-verbindungen, zwischenprodukte, zusammensetzungen und verfahren dafür

Info

Publication number
ATE229535T1
ATE229535T1 AT97307882T AT97307882T ATE229535T1 AT E229535 T1 ATE229535 T1 AT E229535T1 AT 97307882 T AT97307882 T AT 97307882T AT 97307882 T AT97307882 T AT 97307882T AT E229535 T1 ATE229535 T1 AT E229535T1
Authority
AT
Austria
Prior art keywords
benzo
compositions
methods
intermediate products
thiophene compounds
Prior art date
Application number
AT97307882T
Other languages
English (en)
Inventor
Henry Uhlman Bryant
Michael John Martin
Ken Matsumoto
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE229535T1 publication Critical patent/ATE229535T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
    • C07F9/655354—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT97307882T 1996-10-10 1997-10-07 Benzo(6)thiophen-verbindungen, zwischenprodukte, zusammensetzungen und verfahren dafür ATE229535T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2856096P 1996-10-10 1996-10-10

Publications (1)

Publication Number Publication Date
ATE229535T1 true ATE229535T1 (de) 2002-12-15

Family

ID=21844132

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97307882T ATE229535T1 (de) 1996-10-10 1997-10-07 Benzo(6)thiophen-verbindungen, zwischenprodukte, zusammensetzungen und verfahren dafür

Country Status (7)

Country Link
US (1) US5958969A (de)
EP (1) EP0835878B1 (de)
JP (1) JPH10147583A (de)
AT (1) ATE229535T1 (de)
CA (1) CA2217135A1 (de)
DE (1) DE69717759T2 (de)
ES (1) ES2188871T3 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1401446B1 (de) * 2001-05-22 2005-02-09 Eli Lilly And Company Tetrahydrochinolin-derivate zur behandlung von krankheiten ausgelöst durch zu hohem oder zu niedrigem oestrogenspiegel
WO2002094788A1 (en) * 2001-05-22 2002-11-28 Eli Lilly And Company 2-substituted 1,2,3,4-tetrahydroquinolines and derivatives thereof, compositions and methods

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3293263A (en) * 1963-12-09 1966-12-20 Upjohn Co Diphenylbenzocycloalkenes
US3394125A (en) * 1965-10-23 1968-07-23 Bristol Myers Co 2-phenyl-3-tertiary-aminoalkoxy phenyl-and corresponding tertiaryaminoalkyl thio benzfurans substituted in the benzo nucleus with an alkoxy or tertiaryamino alkoxy or alkylthio group
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4230862A (en) * 1975-10-28 1980-10-28 Eli Lilly And Company Antifertility compounds
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
GB8311678D0 (en) * 1983-04-28 1983-06-02 Ici Plc Phenol derivatives
GB8705174D0 (en) * 1987-03-05 1987-04-08 Ici Plc Heterocyclic compounds
US5013761A (en) * 1988-06-03 1991-05-07 Eli Lilly And Company Serotonin antagonists
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
US5254568A (en) * 1990-08-09 1993-10-19 Council Of Scientific & Industrial Research Benzopyrans as antiestrogenic agents
DE4117512A1 (de) * 1991-05-25 1992-11-26 Schering Ag 2-phenylbenzo(b)furane und -thiophene, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
JP3157882B2 (ja) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 新規なベンゾチオフエン誘導体
US5424334A (en) * 1991-12-19 1995-06-13 G. D. Searle & Co. Peptide mimetic compounds useful as platelet aggregation inhibitors
US6756388B1 (en) * 1993-10-12 2004-06-29 Pfizer Inc. Benzothiophenes and related compounds as estrogen agonists
US5384332A (en) * 1994-05-11 1995-01-24 Eli Lilly And Company Methods for inhibiting aortal smooth muscle cell proliferation and restenosis with 1,1,2-triphenylbut-1-ene derivatives
TW398975B (en) * 1994-07-22 2000-07-21 Lilly Co Eli Pharmaceutical composition for inhibiting bone loss
US6479517B1 (en) * 1995-02-28 2002-11-12 Eli Lilly And Company Phosphorous-containing benzothiophenes
US5510357A (en) * 1995-02-28 1996-04-23 Eli Lilly And Company Benzothiophene compounds as anti-estrogenic agents

Also Published As

Publication number Publication date
DE69717759T2 (de) 2003-07-17
JPH10147583A (ja) 1998-06-02
ES2188871T3 (es) 2003-07-01
CA2217135A1 (en) 1998-04-10
EP0835878B1 (de) 2002-12-11
EP0835878A1 (de) 1998-04-15
DE69717759D1 (de) 2003-01-23
US5958969A (en) 1999-09-28

Similar Documents

Publication Publication Date Title
HU9501151D0 (en) Substituted pyridylpyrazoles
ATE504562T1 (de) 7-, 8- und 9-substitutierte tetracyclinverbindungen
ATE207913T1 (de) Benzothiophen-verbindungen, zwischenprodukte, zusammensetzungen und verfahren
PT639577E (pt) Eteres fosfono-oximetilicos ou metiltiometilicos de derivados do taxano como agentes anti-tumor
DE69031158D1 (de) Blasverfahren und Zusammensetzungen
DE69913884D1 (de) Photohärtbare Zusammensetzung und lichtgehärtete geformte Gegenstände
ATE273025T1 (de) Dha-pharmazeutisches produkt konjugate
ATE219938T1 (de) Neue 4-arylpiperazine und 4-arylpiperidine
EP0659211A4 (de) Verfahren und therapeutische zusammensetzungen zur behandlung von zystischer fibrose.
DE69421296D1 (de) Schmelzbehandlung
EP0715164A3 (de) Einrichtung zur Inspektion der Seitenflächen von Presslingen, Fördergerät für Presslinge und Einrichtung zur Inspektion des Aussehens von Presslingen
FI951856L (fi) Farmaseuttinen koostumus osteoporoosin hoitamiseksi
ES2088965T3 (es) Derivados de rodanina aril-sustituidos.
DE69520998D1 (de) Faserbehandlungszusammensetzungen
FI965008L (fi) Koostumukset ja menetelmät kasvainten hoitamiseksi
IL107554A0 (en) Taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
NO974153D0 (no) Anordning for behandling av krumme flater
MX167776B (es) Compuestos volatiles de silicio
FI972306A7 (fi) Substituoituja 2-aryylikarbonyylioksimetyyli-1,2,5-tiadiatsolidin -3- oni-1,1-dioksidi-johdannaisia ja niitä sisältäviä koostumuksia ja mene telmiä niiden käyttämiseksi
DK1146043T3 (da) Taxaner med en alkylsubstitueret sidekæde og farmaceutiske præparater indeholdende disse
DE69739855D1 (de) Benzothiophene und denen enthaltende zusammensetzungen
ATE277026T1 (de) Naphthylverbindungen, zusammensetzungen und verfahren
HUP9800396A3 (en) Pharmaceutical composition for treating dementia
DE69717759D1 (de) Benzo(6)Thiophen-Verbindungen, Zwischenprodukte, Zusammensetzungen und Verfahren dafür
ATE318807T1 (de) Benzo(b)thiophenderivate, zwischenprodukte, zubereitungen und verfahren

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties