ATE229537T1 - Arylsulfon-linker zur massenspektrometrischen analyse - Google Patents

Arylsulfon-linker zur massenspektrometrischen analyse

Info

Publication number
ATE229537T1
ATE229537T1 AT99933033T AT99933033T ATE229537T1 AT E229537 T1 ATE229537 T1 AT E229537T1 AT 99933033 T AT99933033 T AT 99933033T AT 99933033 T AT99933033 T AT 99933033T AT E229537 T1 ATE229537 T1 AT E229537T1
Authority
AT
Austria
Prior art keywords
analyte
arylsulfone
linkers
mass spectrometric
spectrometric analysis
Prior art date
Application number
AT99933033T
Other languages
English (en)
Inventor
Guenter Schmidt
Andrew Hugin Thompson
Robert Alexander Wal Johnstone
Original Assignee
Xzillion Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xzillion Gmbh & Co Kg filed Critical Xzillion Gmbh & Co Kg
Application granted granted Critical
Publication of ATE229537T1 publication Critical patent/ATE229537T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6872—Methods for sequencing involving mass spectrometry

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT99933033T 1998-07-13 1999-07-13 Arylsulfon-linker zur massenspektrometrischen analyse ATE229537T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9815163.2A GB9815163D0 (en) 1998-07-13 1998-07-13 Compounds
PCT/GB1999/002257 WO2000002895A1 (en) 1998-07-13 1999-07-13 Arylsulfone linkers for mass spectrometric analysis

Publications (1)

Publication Number Publication Date
ATE229537T1 true ATE229537T1 (de) 2002-12-15

Family

ID=10835417

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99933033T ATE229537T1 (de) 1998-07-13 1999-07-13 Arylsulfon-linker zur massenspektrometrischen analyse

Country Status (12)

Country Link
EP (1) EP1095053B1 (de)
JP (1) JP3692299B2 (de)
AT (1) ATE229537T1 (de)
AU (1) AU769966B2 (de)
CA (2) CA2337761A1 (de)
DE (1) DE69904478T2 (de)
DK (1) DK1095053T3 (de)
ES (1) ES2189443T3 (de)
GB (2) GB9815163D0 (de)
NZ (1) NZ509518A (de)
PT (1) PT1095053E (de)
WO (1) WO2000002895A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0006141D0 (en) * 2000-03-14 2000-05-03 Brax Group Ltd Mass labels
WO2002029003A2 (en) 2000-10-06 2002-04-11 The Trustees Of Columbia University In The City Of New York Massive parallel method for decoding dna and rna
US9708358B2 (en) 2000-10-06 2017-07-18 The Trustees Of Columbia University In The City Of New York Massive parallel method for decoding DNA and RNA
US7057026B2 (en) 2001-12-04 2006-06-06 Solexa Limited Labelled nucleotides
GB0129012D0 (en) 2001-12-04 2002-01-23 Solexa Ltd Labelled nucleotides
WO2003078446A2 (en) * 2002-03-15 2003-09-25 Nuevolution A/S A building block forming a c-c or a c-hetero atom bond upon reaction
US11008359B2 (en) 2002-08-23 2021-05-18 Illumina Cambridge Limited Labelled nucleotides
ES2407681T3 (es) 2002-08-23 2013-06-13 Illumina Cambridge Limited Nucleótidos modificados para la secuenciación de polinucleótidos.
US7414116B2 (en) 2002-08-23 2008-08-19 Illumina Cambridge Limited Labelled nucleotides
GB0317123D0 (en) * 2003-07-22 2003-08-27 Xzillion Gmbh & Co Kg Characterising polypeptides
JP2005140755A (ja) * 2003-11-10 2005-06-02 Japan Science & Technology Agency 質量分析用プローブ及びそれを用いた質量分析方法
GB0515323D0 (en) 2005-07-26 2005-08-31 Electrophoretics Ltd Mass labels
GB0517097D0 (en) 2005-08-19 2005-09-28 Solexa Ltd Modified nucleosides and nucleotides and uses thereof
GB0518585D0 (en) 2005-09-12 2005-10-19 Electrophoretics Ltd Mass labels
WO2008042067A2 (en) 2006-09-28 2008-04-10 Illumina, Inc. Compositions and methods for nucleotide sequencing
WO2008069973A2 (en) 2006-12-01 2008-06-12 The Trustees Of Columbia University In The City Of New York Four-color dna sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators
GB0704764D0 (en) 2007-03-12 2007-04-18 Electrophoretics Ltd Isobarically labelled reagents and methods of their use
WO2009051807A1 (en) 2007-10-19 2009-04-23 The Trustees Of Columbia University In The City Of New York Design and synthesis of cleavable fluorescent nucleotides as reversible terminators for dna sequencing by synthesis
US9115163B2 (en) 2007-10-19 2015-08-25 The Trustees Of Columbia University In The City Of New York DNA sequence with non-fluorescent nucleotide reversible terminators and cleavable label modified nucleotide terminators
GB0809488D0 (en) 2008-05-23 2008-07-02 Electrophoretics Ltd Mass spectrometric analysis
GB0916881D0 (en) 2009-09-25 2009-11-11 Electrophoretics Ltd Mass labels
WO2012162429A2 (en) 2011-05-23 2012-11-29 The Trustees Of Columbia University In The City Of New York Dna sequencing by synthesis using raman and infrared spectroscopy detection
US10648026B2 (en) 2013-03-15 2020-05-12 The Trustees Of Columbia University In The City Of New York Raman cluster tagged molecules for biological imaging
WO2014139596A1 (en) 2013-03-15 2014-09-18 Illumina Cambridge Limited Modified nucleosides or nucleotides
GB201322567D0 (en) 2013-12-19 2014-02-05 Electrophoretics Ltd Mass labels
US20170089915A1 (en) * 2015-09-30 2017-03-30 Agilent Technologies, Inc. Methods of analyte derivatization and enhanced soft ionization

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5118605A (en) * 1984-10-16 1992-06-02 Chiron Corporation Polynucleotide determination with selectable cleavage sites
US4960700A (en) * 1986-12-24 1990-10-02 Genentech, Inc. Compositions and methods for the synthesis and assay of a mammalian enkephalinase
US5216141A (en) * 1988-06-06 1993-06-01 Benner Steven A Oligonucleotide analogs containing sulfur linkages
JPH08508464A (ja) * 1992-12-16 1996-09-10 ベイヤー コーポレイション カテプシンｄはアルツハイマー病におけるアミロイド生成プロテアーゼである
DE69701671T3 (de) * 1996-01-23 2006-08-17 Qiagen Genomics, Inc., Bothell Verfahren und zusammenstellungen zur sequenzbestimmung von nukleinsäuremolekülen
BR9707060A (pt) * 1996-01-23 1999-12-28 Rapigene Inc Métodos e composições para detectar o ligamento de par ligante usando indicador não-fluorescente.
EP0979305B1 (de) * 1997-01-15 2006-09-27 Xzillion GmbH & CO.KG Massenmarkierte hybridisierungssonden
NZ502088A (en) * 1997-07-11 2002-05-31 Brax Group Ltd Characterising nucleic acids using mass spectroscopy
GB9823646D0 (en) * 1997-12-19 1998-12-23 Brax Genomics Ltd Compounds for mass spectrometry

Also Published As

Publication number Publication date
EP1095053B1 (de) 2002-12-11
AU769966B2 (en) 2004-02-12
AU4921099A (en) 2000-02-01
DE69904478T2 (de) 2003-09-25
GB9916405D0 (en) 1999-09-15
DK1095053T3 (da) 2003-04-07
JP2002520580A (ja) 2002-07-09
WO2000002895A1 (en) 2000-01-20
GB9815163D0 (en) 1998-09-09
GB2340602A (en) 2000-02-23
CA2385987A1 (en) 2000-01-20
JP3692299B2 (ja) 2005-09-07
ES2189443T3 (es) 2003-07-01
EP1095053A1 (de) 2001-05-02
PT1095053E (pt) 2003-04-30
CA2337761A1 (en) 2000-01-20
NZ509518A (en) 2003-07-25
DE69904478D1 (de) 2003-01-23

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