ATE229815T1 - In vitro methoden und verwendung von pharmazeutische zusammensetzungen für die behandlung von innenohrhaarzellen - Google Patents

In vitro methoden und verwendung von pharmazeutische zusammensetzungen für die behandlung von innenohrhaarzellen

Info

Publication number
ATE229815T1
ATE229815T1 AT97949346T AT97949346T ATE229815T1 AT E229815 T1 ATE229815 T1 AT E229815T1 AT 97949346 T AT97949346 T AT 97949346T AT 97949346 T AT97949346 T AT 97949346T AT E229815 T1 ATE229815 T1 AT E229815T1
Authority
AT
Austria
Prior art keywords
treatment
pharmaceutical compositions
inner ear
hair cells
vitro methods
Prior art date
Application number
AT97949346T
Other languages
English (en)
Inventor
Wei-Qiang Gao
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE229815T1 publication Critical patent/ATE229815T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT97949346T 1996-11-01 1997-10-28 In vitro methoden und verwendung von pharmazeutische zusammensetzungen für die behandlung von innenohrhaarzellen ATE229815T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2953696P 1996-11-01 1996-11-01
US08/743,267 US6593290B1 (en) 1996-11-01 1996-11-04 Treatment of inner ear hair cells
PCT/US1997/019585 WO1998019700A1 (en) 1996-11-01 1997-10-28 Treatment of inner ear hair cells

Publications (1)

Publication Number Publication Date
ATE229815T1 true ATE229815T1 (de) 2003-01-15

Family

ID=26705049

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97949346T ATE229815T1 (de) 1996-11-01 1997-10-28 In vitro methoden und verwendung von pharmazeutische zusammensetzungen für die behandlung von innenohrhaarzellen

Country Status (15)

Country Link
US (1) US6593290B1 (de)
EP (1) EP0948349B1 (de)
JP (1) JP4191252B2 (de)
CN (1) CN1313147C (de)
AR (1) AR009603A1 (de)
AT (1) ATE229815T1 (de)
AU (1) AU724988B2 (de)
BR (1) BR9712468A (de)
CA (1) CA2268331C (de)
DE (1) DE69718053T2 (de)
DK (1) DK0948349T3 (de)
ES (1) ES2189002T3 (de)
IL (2) IL129381A0 (de)
WO (1) WO1998019700A1 (de)
ZA (1) ZA979814B (de)

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WO2016037016A1 (en) 2014-09-03 2016-03-10 The Brigham And Women's Hospital, Inc. Compositions, systems, and methods for generating inner ear hair cells for treatment of hearing loss
TWI710635B (zh) 2014-10-09 2020-11-21 美商珍維克公司 編碼人類無調同源物-1(hath1)之腺病毒載體
JP2018504400A (ja) 2015-01-08 2018-02-15 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． Ｌｉｎｇｏ‐１拮抗薬及び脱髄障害の治療のための使用
CN108779437A (zh) 2016-01-08 2018-11-09 麻省理工学院 分化的肠内分泌细胞和胰岛素产生细胞的制备
US11260130B2 (en) 2016-03-02 2022-03-01 Frequency Therapeutics, Inc. Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using a GSK3 inhibitor: IV
US10201540B2 (en) 2016-03-02 2019-02-12 Frequency Therapeutics, Inc. Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: I
US10213511B2 (en) 2016-03-02 2019-02-26 Frequency Therapeutics, Inc. Thermoreversible compositions for administration of therapeutic agents
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Also Published As

Publication number Publication date
CN1251531A (zh) 2000-04-26
DK0948349T3 (da) 2003-04-07
WO1998019700A1 (en) 1998-05-14
AU724988B2 (en) 2000-10-05
CA2268331A1 (en) 1998-05-14
IL129381A0 (en) 2000-02-17
EP0948349B1 (de) 2002-12-18
EP0948349A1 (de) 1999-10-13
IL129381A (en) 2006-07-05
JP4191252B2 (ja) 2008-12-03
US6593290B1 (en) 2003-07-15
ZA979814B (en) 1999-04-30
CA2268331C (en) 2011-07-26
AR009603A1 (es) 2000-04-26
CN1313147C (zh) 2007-05-02
DE69718053D1 (de) 2003-01-30
DE69718053T2 (de) 2003-09-11
ES2189002T3 (es) 2003-07-01
BR9712468A (pt) 1999-10-26
AU7000698A (en) 1998-05-29
JP2002514191A (ja) 2002-05-14

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