ATE230274T1 - Physiologisch aktives polypeptid enthaltende zubereitung mit verzögerter freisetzung und deren herstellung - Google Patents

Physiologisch aktives polypeptid enthaltende zubereitung mit verzögerter freisetzung und deren herstellung

Info

Publication number
ATE230274T1
ATE230274T1 AT99909234T AT99909234T ATE230274T1 AT E230274 T1 ATE230274 T1 AT E230274T1 AT 99909234 T AT99909234 T AT 99909234T AT 99909234 T AT99909234 T AT 99909234T AT E230274 T1 ATE230274 T1 AT E230274T1
Authority
AT
Austria
Prior art keywords
release preparation
polypeptide
physiologically active
sustained
organic solvent
Prior art date
Application number
AT99909234T
Other languages
English (en)
Inventor
Yutaka Yamagata
Masafumi Misaki
Susumu Iwasa
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE230274T1 publication Critical patent/ATE230274T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
AT99909234T 1998-03-20 1999-03-18 Physiologisch aktives polypeptid enthaltende zubereitung mit verzögerter freisetzung und deren herstellung ATE230274T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7185398 1998-03-20
PCT/JP1999/001359 WO1999048519A1 (en) 1998-03-20 1999-03-18 Sustained-release preparation of physiologically active polypeptide and production thereof

Publications (1)

Publication Number Publication Date
ATE230274T1 true ATE230274T1 (de) 2003-01-15

Family

ID=13472521

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99909234T ATE230274T1 (de) 1998-03-20 1999-03-18 Physiologisch aktives polypeptid enthaltende zubereitung mit verzögerter freisetzung und deren herstellung

Country Status (12)

Country Link
US (1) US6482864B1 (de)
EP (1) EP1061948B1 (de)
KR (1) KR20010042079A (de)
CN (1) CN1301172A (de)
AT (1) ATE230274T1 (de)
AU (1) AU744354B2 (de)
BR (1) BR9908936A (de)
CA (1) CA2324568A1 (de)
DE (1) DE69904701T2 (de)
DK (1) DK1061948T3 (de)
WO (1) WO1999048519A1 (de)
ZA (1) ZA200004597B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2383144A1 (en) 1999-09-17 2001-03-29 Takeda Chemical Industries, Ltd. Process for producing protein powder
CA2430934C (en) 2000-12-01 2011-06-21 Takeda Chemical Industries, Ltd. A method of producing sustained-release preparations of a bioactive substance using high-pressure gas
CA2433037C (en) 2000-12-28 2010-12-21 Takeda Chemical Industries, Ltd. Sustained-release preparation
WO2002085399A1 (fr) * 2001-04-20 2002-10-31 Takeda Chemical Industries, Ltd. Preparations contenant un peptide
US20040142043A1 (en) * 2001-07-09 2004-07-22 Atsushi Maeda Sustained-release compositions for injection and process for producing the same
KR100684682B1 (ko) * 2002-09-24 2007-02-22 아사히 가세이 케미칼즈 가부시키가이샤 글리콜산 공중합체 및 그의 제조 방법
EP1694278A4 (de) * 2003-12-16 2009-08-12 Ipsen Pharma Glp-1 pharmazeutische zusammensetzungen
US7582312B2 (en) 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
US7464012B2 (en) * 2004-12-10 2008-12-09 L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude Simplified process simulator
US20070004616A1 (en) * 2005-06-30 2007-01-04 Roland Cherif-Cheikh GLP-1 pharmaceutical compositions
CN101258163B (zh) * 2005-06-30 2013-08-21 益普生制药股份有限公司 Glp-1药物组合物
CA2704111C (en) * 2007-05-14 2017-06-20 Sustained Nano Systems Llc Hypercompressed particles for controlled release of ophthalmic medications
US8071119B2 (en) 2007-05-14 2011-12-06 Sustained Nano Systems Llc Controlled release implantable dispensing device and method
CA2759807C (en) * 2009-04-23 2018-03-20 Sustained Nano Systems Llc Controlled release dispensing device
CN102145160A (zh) * 2011-03-07 2011-08-10 深圳市健元医药科技有限公司 一种lhrh拮抗剂注射用的缓释植入制剂
CN102580056B (zh) * 2011-12-16 2014-04-09 深圳市健元医药科技有限公司 一种含抗利尿成分的缓释注射剂及其制备方法
CN113695370B (zh) * 2021-08-30 2022-06-07 河北科技大学 一种天然低共熔离子液体及其制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962091A (en) 1986-05-23 1990-10-09 Syntex (U.S.A.) Inc. Controlled release of macromolecular polypeptides
ES2062530T3 (es) 1989-05-01 1994-12-16 Alkermes Inc Procedimiento para producir particulas pequeñas de moleculas biologicamente activas.
US5478564A (en) 1990-02-22 1995-12-26 Teva Pharmaceutical Industries, Ltd. Preparation of microparticles for controlled release of water-soluble substances
FR2658432B1 (fr) 1990-02-22 1994-07-01 Medgenix Group Sa Microspheres pour la liberation controlee des substances hydrosolubles et procede de preparation.
EP0625069B1 (de) 1992-10-26 1998-12-30 Schwarz Pharma Ag Verfahren zur herstellung von mikrokapseln
CA2150803C (en) 1992-12-02 2006-01-31 Henry Auer Controlled release growth hormone containing microspheres
US6087324A (en) * 1993-06-24 2000-07-11 Takeda Chemical Industries, Ltd. Sustained-release preparation
NZ260909A (en) 1993-07-05 1995-04-27 Takeda Chemical Industries Ltd Production of sustained release preparation by allowing a water-soluble polypeptide to permeate into a biodegradable matrix in an aqueous solution
AU6242096A (en) * 1995-06-27 1997-01-30 Takeda Chemical Industries Ltd. Method of producing sustained-release preparation
US6190702B1 (en) 1996-03-28 2001-02-20 Takeda Chemical Industries, Ltd. Sustained-released material prepared by dispersing a lyophilized polypeptide in an oil phase
WO1998027980A2 (en) 1996-12-20 1998-07-02 Takeda Chemical Industries, Ltd. Method of producing a sustained-release preparation
US6287587B2 (en) 1997-07-15 2001-09-11 Takeda Chemical Industries, Ltd. Process for producing sustained-release preparation by in-water drying

Also Published As

Publication number Publication date
AU744354B2 (en) 2002-02-21
DK1061948T3 (da) 2003-03-31
DE69904701D1 (de) 2003-02-06
US6482864B1 (en) 2002-11-19
AU2853399A (en) 1999-10-18
WO1999048519A1 (en) 1999-09-30
EP1061948A1 (de) 2000-12-27
BR9908936A (pt) 2005-10-25
KR20010042079A (ko) 2001-05-25
CA2324568A1 (en) 1999-09-30
ZA200004597B (en) 2002-02-27
EP1061948B1 (de) 2003-01-02
CN1301172A (zh) 2001-06-27
DE69904701T2 (de) 2003-11-06

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