ATE230615T1 - Regulierung der systemischen immunantworten mittels zytokinen und antigenen - Google Patents

Regulierung der systemischen immunantworten mittels zytokinen und antigenen

Info

Publication number: ATE230615T1
Authority: AT; Austria
Prior art keywords: systemic immune; antigen; antigens; immune response; cytokines
Prior art date: 1991-10-04

Application number

AT92921896T

Other languages

English (en)

Inventor

Glenn Dranoff

Richard C Mulligan

Drew Pardoll

Original Assignee

Whitehead Biomedical Inst

Univ Johns Hopkins Med

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-04

Filing date

1992-10-05

Publication date

2003-01-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25091012&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE230615(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1992-10-05 Application filed by Whitehead Biomedical Inst, Univ Johns Hopkins Med filed Critical Whitehead Biomedical Inst

2003-01-15 Application granted granted Critical

2003-01-15 Publication of ATE230615T1 publication Critical patent/ATE230615T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00119—Melanoma antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Microbiology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Mycology (AREA)
Epidemiology (AREA)
Zoology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Virology (AREA)
Oncology (AREA)
Wood Science & Technology (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Toxicology (AREA)
Communicable Diseases (AREA)
Physics & Mathematics (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Hematology (AREA)
Plant Pathology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT92921896T 1991-10-04 1992-10-05 Regulierung der systemischen immunantworten mittels zytokinen und antigenen ATE230615T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US77119491A	1991-10-04	1991-10-04
PCT/US1992/008455 WO1993006867A1 (en)	1991-10-04	1992-10-05	The regulation of systemic immune responses utilizing cytokines and antigens

Publications (1)

Publication Number	Publication Date
ATE230615T1 true ATE230615T1 (de)	2003-01-15

Family

ID=25091012

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT92921896T ATE230615T1 (de)	1991-10-04	1992-10-05	Regulierung der systemischen immunantworten mittels zytokinen und antigenen
AT02002123T ATE322286T1 (de)	1991-10-04	1992-10-05	Regulierung der systemischen immunantworten mittels zytokinen und antigenen

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT02002123T ATE322286T1 (de)	1991-10-04	1992-10-05	Regulierung der systemischen immunantworten mittels zytokinen und antigenen

Country Status (8)

Country	Link
EP (2)	EP1216710B1 (de)
JP (1)	JP3580371B2 (de)
AT (2)	ATE230615T1 (de)
AU (1)	AU677165B2 (de)
CA (1)	CA2120503C (de)
DE (2)	DE69232890T2 (de)
ES (1)	ES2189788T3 (de)
WO (1)	WO1993006867A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5662896A (en)	1988-03-21	1997-09-02	Chiron Viagene, Inc.	Compositions and methods for cancer immunotherapy
US5902576A (en) *	1992-10-22	1999-05-11	Yeda Research And Development Co. Ltd. At Weizmann Institute Of Science	Antitumor pharmaceutical composition comprising IL-6 transfected cells
FR2710536B1 (fr) *	1993-09-29	1995-12-22	Transgene Sa	Usage anti-cancéreux d'un vecteur viral comportant un gène modulateur de la réponse immunitaire et/ou inflammatoire.
JPH09506866A (ja) *	1993-12-14	1997-07-08	ジョーンズホプキンスユニバーシティースクールオブメディシン	医薬として活性のある物質の免疫療法のための放出制御
US5478556A (en) *	1994-02-28	1995-12-26	Elliott; Robert L.	Vaccination of cancer patients using tumor-associated antigens mixed with interleukin-2 and granulocyte-macrophage colony stimulating factor
FR2725726B1 (fr) *	1994-10-17	1997-01-03	Centre Nat Rech Scient	Vecteurs viraux et utilisation en therapie genique
ES2176360T3 (es) *	1994-12-30	2002-12-01	Chiron Corp	Combinacion de vehiculos de administracion de genes.
US6251957B1 (en)	1995-02-24	2001-06-26	Trustees Of The University Of Pennsylvania	Method of reducing an immune response to a recombinant virus
US6372208B1 (en)	1999-09-28	2002-04-16	The Trustees Of The University Of Pennsylvania	Method of reducing an immune response to a recombinant virus
WO1997000085A1 (en) *	1995-06-19	1997-01-03	University Of Medicine & Dentistry Of New Jersey	Gene therapy of solid tumors with interferons alone or with other immuno-effector proteins
US5837231A (en) *	1996-06-27	1998-11-17	Regents Of The University Of Minnesota	GM-CSF administration for the treatment and prevention of recurrence of brain tumors
AU3889997A (en) *	1996-08-16	1998-03-06	Johns Hopkins University School Of Medicine, The	Melanoma cell lines expressing shared immunodominant melanoma antigens nd methods of using same
EP0834323A1 (de) *	1996-09-30	1998-04-08	Introgene B.V.	Cytokin-Gentherapie für die Behandlung von malignen Tumoren
GB9827104D0 (en) *	1998-12-10	1999-02-03	Onyvax Ltd	New cancer treatments
ATE421328T1 (de) *	2002-02-22	2009-02-15	Intracel Recources Llc	Sterile immunogene nicht-tumorigene tumorzell- zusammensetzungen und verfahren
US7176022B2 (en)	2002-12-20	2007-02-13	Cell Genesys, Inc.	Directly injectable formulations which provide enhanced cryoprotection of cell products
US20050019336A1 (en)	2003-07-23	2005-01-27	Dalgleish Angus George	Human prostate cell lines in cancer treatment
WO2005063280A1 (de)	2003-12-30	2005-07-14	Mologen Ag	Allogenes tumortherapeutikum
KR20240024328A (ko)	2016-11-22	2024-02-23	알로플렉스 바이오테라퓨틱스	동종이형 종양 세포 백신

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3875859T2 (de) *	1987-03-02	1993-05-13	Genetics Inst	Zubereitungen zur verbesserung der adcc-therapien.
DE3922444A1 (de) *	1988-03-01	1991-01-10	Deutsches Krebsforsch	Virusmodifizierte tumorvakzine fuer die immuntherapie von tumormetastasen
DE3806565A1 (de) *	1988-03-01	1989-09-14	Deutsches Krebsforsch	Virusmodifizierte tumorvakzinen fuer die immuntherapie von tumormetastasen
DE69114299T3 (de) *	1990-09-14	2005-09-15	The Johns Hopkins University	Verfahren und zusammensetzungen für gentherapie und stärkung des immunsystems.
DE69123981T3 (de) *	1990-10-31	2006-06-14	Cell Genesys Inc	Nützliche retrovirale vektoren für die gentherapie

1992
- 1992-10-05 AT AT92921896T patent/ATE230615T1/de not_active IP Right Cessation
- 1992-10-05 DE DE69232890T patent/DE69232890T2/de not_active Expired - Lifetime
- 1992-10-05 WO PCT/US1992/008455 patent/WO1993006867A1/en not_active Ceased
- 1992-10-05 JP JP50711093A patent/JP3580371B2/ja not_active Expired - Lifetime
- 1992-10-05 AU AU27776/92A patent/AU677165B2/en not_active Expired
- 1992-10-05 EP EP02002123A patent/EP1216710B1/de not_active Expired - Lifetime
- 1992-10-05 AT AT02002123T patent/ATE322286T1/de not_active IP Right Cessation
- 1992-10-05 ES ES92921896T patent/ES2189788T3/es not_active Expired - Lifetime
- 1992-10-05 CA CA002120503A patent/CA2120503C/en not_active Expired - Lifetime
- 1992-10-05 DE DE69233614T patent/DE69233614T2/de not_active Expired - Lifetime
- 1992-10-05 EP EP92921896A patent/EP0607309B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPH07502987A (ja)	1995-03-30
DE69233614T2 (de)	2007-02-15
WO1993006867A1 (en)	1993-04-15
EP1216710A1 (de)	2002-06-26
DE69232890D1 (de)	2003-02-13
AU2777692A (en)	1993-05-03
CA2120503C (en)	2006-04-04
DE69233614D1 (de)	2006-05-18
ES2189788T3 (es)	2003-07-16
EP1216710B1 (de)	2006-04-05
JP3580371B2 (ja)	2004-10-20
CA2120503A1 (en)	1993-04-15
AU677165B2 (en)	1997-04-17
EP0607309B1 (de)	2003-01-08
EP0607309A1 (de)	1994-07-27
DE69232890T2 (de)	2003-10-09
ATE322286T1 (de)	2006-04-15

Legal Events

Date	Code	Title	Description
2003-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE322286T1 (de)	2006-04-15	Regulierung der systemischen immunantworten mittels zytokinen und antigenen
FI920132A0 (fi)	1992-01-13	Stabila vaccinkompositioner innehaollande interleukiner.
NO970993D0 (no)	1997-03-04	Mutant enterotoksin som er effektiv som en ikke-toksisk oral adjuvant
AU6385486A (en)	1987-04-16	Sustained release composition
NO943920L (no)	1994-10-14	Vaksineadjuvans
TR200001705T2 (tr)	2001-07-23	''İmidazonaftiridinler ve bunların sitokin biyosentezinin indüklenmesinde kullanılması''
DK0667901T4 (da)	2008-11-10	Hidtil ukendt cytokin
ATE105334T1 (de)	1994-05-15	Schimaerische glykoproteine enthaltende immunogenische abschnitte von menschlichem parainfluenzavirus typ 3.
FI851859L (fi)	1985-11-13	Antigenpreparat och isolering av saodana preparat.
ATE66613T1 (de)	1991-09-15	Immunstimulierende mittel.
DE69112968D1 (de)	1995-10-19	Aufbau eines regelbaren dämpfers.
DE69300929D1 (de)	1996-01-18	Universaldübel.
FI891283A0 (fi)	1989-03-17	Ifosfamid-mesna-lyofilisat och foerfarande foer dess framstaellning.
DE69034166D1 (de)	2004-10-28	Azellulärer Impfstoff
IT1227972B (it)	1991-05-20	Meccanismo regolabile del flusso d'aria di un ambiente.
FI892222A0 (fi)	1989-05-09	Peptidalkoholer med antikoagulantverkan.
IT8049162A0 (it)	1980-07-03	Belli poltrone e simili dispositivo per trasmissione aerea di impulsi ultrasuonici atto alla regolazione della posizione di sga
DE3867220D1 (de)	1992-02-06	Gasleit der schalldaempfungseinrichtung fuer drehkolbenverdichter.
ITMI920879A1 (it)	1993-10-10	Determinazione della velocita' di volo reale di missili
EP0351876A3 (de)	1990-04-18	Zusammensetzung zur Steigerung der Impfungswirkung
NO922304D0 (no)	1992-06-11	Eliminering av aktiverte lymfocytter
DK324276A (da)	1977-01-24	Afgangsluftlygte med indstillelig tallerkenventil
EP0563288A4 (en)	1994-08-24	Immunopotentiation of vaccines, particularly swine pleuropneumonia vaccines
DK0542895T3 (da)	1997-05-12	Krydsreaktiv influenza A immunisering
ATE60765T1 (de)	1991-02-15	Pyranderivate.