ATE230923T1 - Verfahren und zusammensetzungen zur herstellung getrockneter, lagerungsstabiler blutplättchen - Google Patents

Verfahren und zusammensetzungen zur herstellung getrockneter, lagerungsstabiler blutplättchen

Info

Publication number
ATE230923T1
ATE230923T1 AT98904260T AT98904260T ATE230923T1 AT E230923 T1 ATE230923 T1 AT E230923T1 AT 98904260 T AT98904260 T AT 98904260T AT 98904260 T AT98904260 T AT 98904260T AT E230923 T1 ATE230923 T1 AT E230923T1
Authority
AT
Austria
Prior art keywords
compositions
storage
producing dried
stable blood
blood plates
Prior art date
Application number
AT98904260T
Other languages
English (en)
Inventor
Valentine Charlton Menys
Diana Johanna Phipps
Lynda Mary Grandage
Bruce Joseph Roser
Original Assignee
Elan Drug Delivery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Drug Delivery Ltd filed Critical Elan Drug Delivery Ltd
Application granted granted Critical
Publication of ATE230923T1 publication Critical patent/ATE230923T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331—Preservative, buffer, anticoagulant or diluent

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98904260T 1997-02-07 1998-02-06 Verfahren und zusammensetzungen zur herstellung getrockneter, lagerungsstabiler blutplättchen ATE230923T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3749397P 1997-02-07 1997-02-07
PCT/GB1998/000375 WO1998034478A1 (en) 1997-02-07 1998-02-06 Methods and compositions for producing dried, storage-stable platelets

Publications (1)

Publication Number Publication Date
ATE230923T1 true ATE230923T1 (de) 2003-02-15

Family

ID=21894636

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98904260T ATE230923T1 (de) 1997-02-07 1998-02-06 Verfahren und zusammensetzungen zur herstellung getrockneter, lagerungsstabiler blutplättchen

Country Status (12)

Country Link
US (1) US6221575B1 (de)
EP (1) EP0967862B1 (de)
JP (1) JP2001511174A (de)
CN (1) CN1246778A (de)
AT (1) ATE230923T1 (de)
AU (1) AU732274B2 (de)
CA (1) CA2279376A1 (de)
DE (1) DE69810755T2 (de)
DK (1) DK0967862T3 (de)
ES (1) ES2190063T3 (de)
WO (1) WO1998034478A1 (de)
ZA (1) ZA981031B (de)

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DE60002103T2 (de) 1999-11-12 2003-12-18 Elan Drug Delivery Ltd., Ruddington Stabilisierung von blutplättchen
DE19964109A1 (de) 1999-12-29 2001-07-05 Dade Behring Marburg Gmbh Gebrauchsfertiges langzeitstabiles Ristocetin Cofaktor Testreagenz
CA2397362A1 (en) 2000-02-10 2001-08-16 The Regents Of The University Of California Therapeutic platelets and methods
DE10010959A1 (de) * 2000-03-06 2001-09-20 Eppendorf Geraetebau Netheler Verfahren zum Übertragen von Material in einem Zellsystem
US6653062B1 (en) * 2000-07-26 2003-11-25 Wisconsin Alumni Research Foundation Preservation and storage medium for biological materials
US8101077B2 (en) * 2001-05-07 2012-01-24 Sivaprasad Sukavaneshvar Device for separating platelets from fluid suspensions
US7011852B2 (en) * 2001-05-07 2006-03-14 Hemogenesis, Llc Separation of platelets from whole blood for use as a healant
AU2003268033A1 (en) * 2002-07-26 2004-02-16 The General Hospital Corporation Systems and methods for cell preservation
AU2003304289A1 (en) * 2002-11-29 2005-01-21 The Regents Of The University Of California A method and therapeutic platelets
JP2008509226A (ja) 2004-05-24 2008-03-27 ジェンボールト コーポレイション 回収可能な形式での安定なタンパク質保管および安定な核酸保管
US7811558B2 (en) * 2004-08-12 2010-10-12 Cellphire, Inc. Use of stabilized platelets as hemostatic agent
EP1784639B1 (de) * 2004-08-12 2010-01-20 CELLPHIRE, Inc. Verfahren zur herstellung gefriergetrockneter blutplättchen, gefriergetrocknete blutplättchen enthaltende zusammensetzungen und verwendungsverfahren
US20060035383A1 (en) * 2004-08-12 2006-02-16 David Ho Dry platelet preparations for use in diagnostics
WO2008051245A2 (en) * 2005-12-02 2008-05-02 Novartis Ag Nanoparticles for use in immunogenic compositions
US8097403B2 (en) * 2006-12-14 2012-01-17 Cellphire, Inc. Freeze-dried platelets, method of making and method of use as a diagnostic agent
US20090081785A1 (en) * 2007-09-24 2009-03-26 Hememics Biotechnologies, Inc. Desiccated Biologics And Methods Of Preparing The Same
US20090090022A1 (en) * 2007-10-09 2009-04-09 Hememics Biotechnologies, Inc. Desiccation Chamber and Methods for Drying Biological Materials
WO2009155612A2 (en) * 2008-06-20 2009-12-23 Genvault Corporation Sample collection and storage devices and methods of use thereof
CN102177237B (zh) 2008-09-12 2013-10-30 金沃特公司 用于贮存和稳定生物分子的基质和介质
US8734854B2 (en) * 2009-07-09 2014-05-27 Orogen Biosciences Inc. Process for removing growth factors from platelets
US20110183311A1 (en) * 2010-01-27 2011-07-28 David Ho Dry platelet preparations for use in diagnostics
WO2011103114A1 (en) * 2010-02-17 2011-08-25 Hememics Biotechnologies, Inc. Preservation solutions for biologics and methods related thereto
US8802363B2 (en) * 2010-04-08 2014-08-12 Inserm (Institut National De La Sante Et De La Recherche Medicale) Zeodration method for the preservation of blood platelets
CN101957364A (zh) * 2010-09-19 2011-01-26 李勇 冻干型血小板抗原谱细胞的制备方法
CN102327288B (zh) * 2011-10-17 2012-11-14 济南环肽医药科技有限公司 一种注射用血小板冻干粉制剂及其制备方法
EP3769618A1 (de) 2014-06-09 2021-01-27 Terumo BCT, Inc. Behälter zur lyophilisierung
CN104964909B (zh) * 2015-05-28 2018-04-24 上海市血液中心 一种血小板跨膜电位检测方法
US10448631B2 (en) 2015-09-22 2019-10-22 East Carolina University Cryopreservation using sucralose
CN111295094A (zh) 2017-10-09 2020-06-16 泰尔茂比司特生物技术有限公司 冻干容器及使用冻干容器的方法
AU2019387368A1 (en) 2018-11-30 2021-06-17 Cellphire, Inc. Platelets as delivery agents
WO2020112963A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets as delivery agents
WO2020185916A1 (en) 2019-03-14 2020-09-17 Terumo Bct Biotechnologies, Llc Lyophilization container fill fixture, system and method of use
CA3138529C (en) * 2019-05-03 2025-10-07 Cellphire, Inc. MATERIALS AND PROCESSES FOR THE PRODUCTION OF BLOOD PRODUCTS
CA3150936A1 (en) 2019-08-16 2021-02-25 Cellphire, Inc. Thrombosomes as an antiplatelet agent reversal agent
EP4013432A4 (de) * 2019-08-16 2023-10-18 Cellphire Inc. Thrombosomen als mittel zur aufhebung der gerinnungshemmenden wirkung
CA3170198A1 (en) * 2020-02-04 2021-08-12 Cellphire, Inc Methods of treating acquired hemophilia with anti-fibrinolytic loaded platelets
US20220273724A1 (en) 2021-02-17 2022-09-01 Cellphire Inc. Freeze-dried platelet derivative compositions for treating antiplatelet induced coagulopathy
US20240164367A1 (en) * 2021-04-20 2024-05-23 Retham Technologies, Llc Methods for maintaining long-term platelet viability and activatability
WO2024233577A1 (en) 2023-05-11 2024-11-14 Vetstem, Inc. Platelet-rich plasma compositions, preparation, and uses thereof

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CH660634A5 (de) 1983-08-30 1987-05-15 Dimitrios Giannitsis Verfahren zur herstellung von natuerlichem immunoadsorbens.
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US5242792A (en) * 1991-02-25 1993-09-07 The United States Of America As Represented By The Secretary Of The Navy Method for the preservation of red blood cells by lyophilization using glycerol or inositol with disaccharides
GB9114202D0 (en) 1991-07-01 1991-08-21 Quadrant Holdings Cambridge Blood products
WO1993014191A1 (en) * 1992-01-21 1993-07-22 Cryopharm Corporation Method of freezing cells and cell-like materials
DE69333924T2 (de) * 1992-05-29 2006-08-17 University Of North Carolina At Chapel Hill Im immobilisierten Zustand getrocknete pharmazeutisch verträgliche menschliche Blutplättchen
JPH06154318A (ja) 1992-11-25 1994-06-03 Fukuda Sangyo Kaihatsu Center Kk 点滴用輸液量測定装置
EP0668013B1 (de) * 1994-02-22 2005-04-20 Nippon Telegraph And Telephone Corporation Gefriergetrocknete Blutzellen, Stammzellen und Plättchen und Verfahren zu deren Herstellung
JPH0920687A (ja) * 1995-07-03 1997-01-21 Nippon Telegr & Teleph Corp <Ntt> 凍結乾燥血液の戻し液
US5827741A (en) * 1996-11-19 1998-10-27 The Regents Of The University Of California Cryopreservation of human adult and fetal pancreatic cells and human platelets

Also Published As

Publication number Publication date
AU732274B2 (en) 2001-04-12
JP2001511174A (ja) 2001-08-07
DE69810755D1 (de) 2003-02-20
CA2279376A1 (en) 1998-08-13
EP0967862A1 (de) 2000-01-05
WO1998034478A1 (en) 1998-08-13
DK0967862T3 (da) 2003-05-12
EP0967862B1 (de) 2003-01-15
DE69810755T2 (de) 2003-08-07
ES2190063T3 (es) 2003-07-16
CN1246778A (zh) 2000-03-08
AU6220898A (en) 1998-08-26
ZA981031B (en) 1998-08-11
US6221575B1 (en) 2001-04-24

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