ATE231002T1 - Menschliche, neutralisierende, monoklonale antikörper gegen das respiratorische synzytialvirus - Google Patents

Menschliche, neutralisierende, monoklonale antikörper gegen das respiratorische synzytialvirus

Info

Publication number
ATE231002T1
ATE231002T1 AT93921646T AT93921646T ATE231002T1 AT E231002 T1 ATE231002 T1 AT E231002T1 AT 93921646 T AT93921646 T AT 93921646T AT 93921646 T AT93921646 T AT 93921646T AT E231002 T1 ATE231002 T1 AT E231002T1
Authority
AT
Austria
Prior art keywords
monoclonal antibodies
pct
virus
synzytial
antibodies against
Prior art date
Application number
AT93921646T
Other languages
English (en)
Inventor
Dennis R Burton
Carlos F Barbas Iii
Robert M Chanock
Brian R Murphy
James E Crowe Jr
Original Assignee
Scripps Research Inst
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst, Us Gov Health & Human Serv filed Critical Scripps Research Inst
Application granted granted Critical
Publication of ATE231002T1 publication Critical patent/ATE231002T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1006—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being against or targeting material from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/11—Paramyxoviridae (F); Pneumoviridae (F), e.g. respiratory syncytial virus [RSV]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
AT93921646T 1992-09-16 1993-09-16 Menschliche, neutralisierende, monoklonale antikörper gegen das respiratorische synzytialvirus ATE231002T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94551592A 1992-09-16 1992-09-16
PCT/US1993/008786 WO1994006448A1 (en) 1992-09-16 1993-09-16 Human neutralizing monoclonal antibodies to respiratory syncytial virus

Publications (1)

Publication Number Publication Date
ATE231002T1 true ATE231002T1 (de) 2003-02-15

Family

ID=25483204

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93921646T ATE231002T1 (de) 1992-09-16 1993-09-16 Menschliche, neutralisierende, monoklonale antikörper gegen das respiratorische synzytialvirus

Country Status (12)

Country Link
US (1) US5762905A (de)
EP (1) EP0671927B1 (de)
JP (1) JP3976333B2 (de)
AT (1) ATE231002T1 (de)
AU (1) AU686113B2 (de)
CA (1) CA2144043C (de)
DE (1) DE69332643T2 (de)
DK (1) DK0671927T3 (de)
ES (1) ES2191016T3 (de)
FI (2) FI108991B (de)
NO (1) NO323768B1 (de)
WO (1) WO1994006448A1 (de)

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EP0853487B1 (de) 1995-09-18 2000-07-05 Intracel Corporation Neutralisierende monoklonale antikörper gegen respiratorischen synzytialvirus
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ITRM960808A1 (it) * 1996-11-26 1998-05-26 Rossolini Gianmaria Immunoconiugati comprendenti anticorpi monoclonali umani o frammenti di essi per diagnosi in vivo e terapia
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US7229619B1 (en) 2000-11-28 2007-06-12 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
WO2001064751A2 (en) 2000-03-01 2001-09-07 Medimmune, Inc. High potency recombinant antibodies and method for producing them
US20050175986A1 (en) * 2000-05-09 2005-08-11 Smit Kline Beecham Corporation Human monoclonal antibody
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US7179900B2 (en) * 2000-11-28 2007-02-20 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
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EP2486941B1 (de) 2006-10-02 2017-03-15 E. R. Squibb & Sons, L.L.C. CXCR4-bindende humane Antikörper und deren Verwendungen
BRPI0717902A2 (pt) 2006-12-01 2013-10-29 Medarex Inc "anticorpo monoclonal humano isolado, composição, conjugado anticorpo-molécula parceria, imunoconjugado, molécula de ácido nucléico isolada, vetor de expressão, célula hospedeira, método para prepar um anticorpo anti-cd22, método para inibir o desenvolvimento de uma célula tumoral que expressa cd22 e método para tratar uma doença inflamatória ou autoimuneem um indivíduo"
CL2007003622A1 (es) 2006-12-13 2009-08-07 Medarex Inc Anticuerpo monoclonal humano anti-cd19; composicion que lo comprende; y metodo de inhibicion del crecimiento de celulas tumorales.
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AR072999A1 (es) 2008-08-11 2010-10-06 Medarex Inc Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
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TWI659968B (zh) 2013-03-14 2019-05-21 再生元醫藥公司 針對呼吸道融合病毒ｆ蛋白質的人類抗體及其使用方法
JO3555B1 (ar) 2015-10-29 2020-07-05 Merck Sharp & Dohme جسم مضاد يبطل فعالية فيروس الالتهاب الرئوي البشري
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US11479600B2 (en) 2016-10-21 2022-10-25 Adimab, Llc Anti-respiratory syncytial virus antibodies, and methods of their generation and use
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CN113015748B (zh) 2018-10-31 2025-12-12 默沙东有限责任公司 抗人pd-1抗体晶体及其使用方法
CN113316458B (zh) 2018-11-07 2024-08-02 默沙东有限责任公司 抗lag3抗体和抗pd-1抗体的共制剂
CN109762067B (zh) 2019-01-17 2020-02-28 北京天广实生物技术股份有限公司 结合人Claudin 18.2的抗体及其用途
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Also Published As

Publication number Publication date
ES2191016T3 (es) 2003-09-01
NO950881L (no) 1995-05-15
FI108991B (fi) 2002-05-15
US5762905A (en) 1998-06-09
NO323768B1 (no) 2007-07-02
EP0671927B1 (de) 2003-01-15
CA2144043C (en) 2005-01-18
DE69332643D1 (de) 2003-02-20
DE69332643T2 (de) 2003-11-27
AU4927193A (en) 1994-04-12
EP0671927A4 (de) 1997-05-21
DK0671927T3 (da) 2003-04-22
EP0671927A1 (de) 1995-09-20
FI951164L (fi) 1995-05-12
NO950881D0 (no) 1995-03-07
FI20020184L (fi) 2002-01-31
FI111553B (fi) 2003-08-15
JPH08505520A (ja) 1996-06-18
FI951164A0 (fi) 1995-03-13
AU686113B2 (en) 1998-02-05
WO1994006448A1 (en) 1994-03-31
JP3976333B2 (ja) 2007-09-19
CA2144043A1 (en) 1994-03-31

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