ATE231147T1 - Antidepressiv und gegen die parkinsonsche krankheit wirkende verbindungen - Google Patents

Antidepressiv und gegen die parkinsonsche krankheit wirkende verbindungen

Info

Publication number
ATE231147T1
ATE231147T1 AT93610065T AT93610065T ATE231147T1 AT E231147 T1 ATE231147 T1 AT E231147T1 AT 93610065 T AT93610065 T AT 93610065T AT 93610065 T AT93610065 T AT 93610065T AT E231147 T1 ATE231147 T1 AT E231147T1
Authority
AT
Austria
Prior art keywords
antidepressant
parkinson
compounds
disease compounds
disease
Prior art date
Application number
AT93610065T
Other languages
English (en)
Inventor
Peter Moldt
Jorgen Scheel-Krueger
Leif Helth Jensen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK921541A external-priority patent/DK154192D0/da
Application filed by Neurosearch As filed Critical Neurosearch As
Application granted granted Critical
Publication of ATE231147T1 publication Critical patent/ATE231147T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Hydrogenated Pyridines (AREA)
AT93610065T 1992-12-23 1993-12-20 Antidepressiv und gegen die parkinsonsche krankheit wirkende verbindungen ATE231147T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK921541A DK154192D0 (da) 1992-12-23 1992-12-23 Heterocycliske forbindelser
US08/093,182 US5374636A (en) 1992-12-23 1993-07-16 2,3-trans-disubstituted tropane compounds which have useful pharmaceutical utility

Publications (1)

Publication Number Publication Date
ATE231147T1 true ATE231147T1 (de) 2003-02-15

Family

ID=26065882

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93610065T ATE231147T1 (de) 1992-12-23 1993-12-20 Antidepressiv und gegen die parkinsonsche krankheit wirkende verbindungen

Country Status (9)

Country Link
EP (1) EP0604354B1 (de)
JP (1) JP3841449B2 (de)
AT (1) ATE231147T1 (de)
AU (1) AU672052B2 (de)
CA (1) CA2112084C (de)
DE (1) DE69332636T2 (de)
FI (1) FI935800A7 (de)
NO (1) NO303578B1 (de)
NZ (1) NZ250515A (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0697871A4 (de) * 1993-05-18 1998-04-22 Univ Wake Forest Behandlungsverfahren mit biologisch aktiven tropanderivaten
BR9507489A (pt) * 1994-04-19 1997-08-12 Neurosearch As Derivados tropano sua preparacão e uso
ATE362931T1 (de) * 1995-10-13 2007-06-15 Neurosearch As 8-azabicyclo(3.2.1)oct-2en-derivate, deren herstellung und anwendung
JP3238414B2 (ja) * 1996-02-22 2001-12-17 ニューロサーチ・アクティーゼルスカブ トロパン―誘導体、その製造方法及びその使用方法
WO1999038866A1 (en) * 1998-01-28 1999-08-05 Neurosearch A/S 8-azabicyclo[3.2.1]oct-2-ene derivatives in labelled form and use of 8-azabicyclo[3.2.1]oct-2-ene derivatives in labelled and unlabelled form
CA2335336A1 (en) * 1998-06-19 1999-12-23 James Edmund Audia Inhibition of serotonin reuptake
RU2211216C2 (ru) * 1998-12-22 2003-08-27 Мерк Патент Гмбх Производные амидов и мочевины в качестве ингибиторов вторичного поглощения 5-ht и лигандов 5-ht1b/1d
DE60135634D1 (de) * 2000-01-11 2008-10-16 Molecular Insight Pharm Inc Polypharmacophore verbindungen
EP1417174A2 (de) * 2001-08-08 2004-05-12 Neurosearch A/S Substituierte amin derivative und ihre verwendung als inhibitoren der monomin-aufname
EP1429811A4 (de) * 2001-08-17 2006-05-17 Harvard College Theurapeutische tropanverbindungen
WO2003045388A1 (en) 2001-11-30 2003-06-05 Neurosearch A/S Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases
JP2006517568A (ja) * 2003-02-12 2006-07-27 ニューロサーチ、アクティーゼルスカブ ８−アザ−ビシクロ［３．２．１］オクタン誘導体及びこれをモノアミン神経伝達物質再取り込み阻害薬として使用する方法
JP2006517567A (ja) * 2003-02-12 2006-07-27 ニューロサーチ、アクティーゼルスカブ 新規８−アザ−ビシクロ［３．２．１］オクタン誘導体及びこれをモノアミン神経伝達物質再取り込み阻害薬として使用する方法
JP2007508336A (ja) * 2003-10-16 2007-04-05 ニューロサーチ、アクティーゼルスカブ モノアミン神経伝達物質再取り込みインヒビター及びアセチルコリンエステラーゼインヒビターを含む医薬組成物
WO2007028770A1 (en) * 2005-09-05 2007-03-15 Neurosearch A/S Monoamine neurotransmitter re-uptake inhibitors for neuroprotection in patients suffering from an advanced stage of a mental disease
EP1779851A1 (de) 2005-10-31 2007-05-02 Boehringer Ingelheim Pharma GmbH & Co.KG Behandlung von Diabetes

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3813404A (en) * 1972-11-15 1974-05-28 Sterling Drug Inc Tropane-2-carboxylates and derivatives
US3901892A (en) * 1973-12-14 1975-08-26 Sterling Drug Inc 1,3-ethanoindeno(2,1-c)-pyridines and 1,3-ethanobenz(g)isoquinolines
FR2276823A1 (fr) * 1974-07-04 1976-01-30 Roussel Uclaf Nouveaux derives de la dibenzo(b.e)thiepine et leurs sels, procede de preparation et application a titre de medicaments desdits produits
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
IL88156A (en) * 1987-11-13 1997-02-18 Novo Nordisk As Azacyclic compounds their preparation and pharmaceutical compositions containing them
NZ227684A (en) * 1988-01-30 1991-07-26 Merck Sharp & Dohme Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions
ES2098248T3 (es) * 1989-05-17 1997-05-01 Pfizer Derivados de 2-piperidino-1-alcanoles como agentes antiisquemicos.
DK198590D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK0644775T3 (da) * 1991-11-15 2000-03-06 Nat Inst Health Kokainreceptorbindende ligander
US5262428A (en) * 1992-03-13 1993-11-16 Wake Forest University Biologically active tropane derivatives
US5268480A (en) * 1992-09-22 1993-12-07 Mayo Foundation For Medical Education And Research Cocaine analogs

Also Published As

Publication number Publication date
NO934761D0 (no) 1993-12-22
JP3841449B2 (ja) 2006-11-01
DE69332636D1 (de) 2003-02-20
AU672052B2 (en) 1996-09-19
AU5236293A (en) 1994-07-07
JPH06293758A (ja) 1994-10-21
FI935800L (fi) 1994-06-24
NO934761L (no) 1994-06-24
CA2112084A1 (en) 1994-06-24
NZ250515A (en) 1996-09-25
NO303578B1 (no) 1998-08-03
EP0604354B1 (de) 2003-01-15
FI935800A7 (fi) 1994-06-24
CA2112084C (en) 2002-06-11
FI935800A0 (fi) 1993-12-22
EP0604354A3 (de) 1995-02-08
EP0604354A2 (de) 1994-06-29
DE69332636T2 (de) 2003-09-11

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