ATE231835T1 - Anti-tumor-mittel - Google Patents

Anti-tumor-mittel

Info

Publication number: ATE231835T1
Authority: AT; Austria
Prior art keywords: alkyl; hydrogen; tumor agents; akanesulphonyloxy; alkanesulphonyloxy
Prior art date: 1998-03-20

Application number

AT99909099T

Other languages

English (en)

Inventor

Francis Thomas Boyle

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-20

Filing date

1999-03-16

Publication date

2003-02-15

1999-03-16 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2003-02-15 Application granted granted Critical

2003-02-15 Publication of ATE231835T1 publication Critical patent/ATE231835T1/de

Links

239000002246 antineoplastic agent Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000003282 alkyl amino group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
230000001028 anti-proliverative effect Effects 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
-1 benzenesulphonyloxy Chemical group 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/34—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having amino groups and esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Saccharide Compounds (AREA)
Hydrogenated Pyridines (AREA)

AT99909099T 1998-03-20 1999-03-16 Anti-tumor-mittel ATE231835T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9805866.2A GB9805866D0 (en)	1998-03-20	1998-03-20	Anti-tumour agents
PCT/GB1999/000787 WO1999048857A1 (en)	1998-03-20	1999-03-16	Anti-tumour agents

Publications (1)

Publication Number	Publication Date
ATE231835T1 true ATE231835T1 (de)	2003-02-15

Family

ID=10828858

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99909099T ATE231835T1 (de)	1998-03-20	1999-03-16	Anti-tumor-mittel

Country Status (18)

Country	Link
US (1)	US6346633B1 (de)
EP (1)	EP1064253B1 (de)
JP (1)	JP2002507590A (de)
KR (1)	KR20010042055A (de)
CN (1)	CN1293654A (de)
AT (1)	ATE231835T1 (de)
AU (1)	AU756651B2 (de)
BR (1)	BR9908932A (de)
CA (1)	CA2324361A1 (de)
DE (1)	DE69905142T2 (de)
DK (1)	DK1064253T3 (de)
ES (1)	ES2190199T3 (de)
GB (1)	GB9805866D0 (de)
IL (1)	IL138589A (de)
NO (1)	NO20004662L (de)
NZ (1)	NZ505856A (de)
WO (1)	WO1999048857A1 (de)
ZA (1)	ZA200004387B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9805868D0 (en)	1998-03-20	1998-05-13	Zeneca Ltd	Anti-tumour agents
US20060099712A1 (en) *	2004-11-08	2006-05-11	Eastman Kodak Company	Correlation of anti-cancer activity of dyes with redox potentials
CA3029228A1 (en) *	2016-06-27	2018-01-04	Systems Oncology, Llc	Combination chemotherapies
CA3136725A1 (en) *	2019-04-12	2020-10-15	Tonix Pharmaceuticals Holding Corp.	Inhibitors of cd40-cd154 binding

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2862107D1 (en)	1977-12-02	1982-11-18	Takeda Chemical Industries Ltd	Glucosamine-peptide derivatives and their pharmaceutical compositions
JPS58177934A (ja)	1982-04-13	1983-10-18	Takeda Chem Ind Ltd	ベンゾキノン誘導体
NZ240785A (en)	1991-11-28	1995-08-28	Cancer Res Campaign Tech	Substituted nitro aniline derivatives and medicaments
GB9805868D0 (en)	1998-03-20	1998-05-13	Zeneca Ltd	Anti-tumour agents

1998
- 1998-03-20 GB GBGB9805866.2A patent/GB9805866D0/en not_active Ceased
1999
- 1999-03-16 BR BR9908932-7A patent/BR9908932A/pt not_active IP Right Cessation
- 1999-03-16 DK DK99909099T patent/DK1064253T3/da active
- 1999-03-16 WO PCT/GB1999/000787 patent/WO1999048857A1/en not_active Ceased
- 1999-03-16 AU AU28468/99A patent/AU756651B2/en not_active Ceased
- 1999-03-16 CN CN99804243A patent/CN1293654A/zh active Pending
- 1999-03-16 EP EP99909099A patent/EP1064253B1/de not_active Expired - Lifetime
- 1999-03-16 US US09/646,459 patent/US6346633B1/en not_active Expired - Fee Related
- 1999-03-16 NZ NZ505856A patent/NZ505856A/xx unknown
- 1999-03-16 KR KR1020007010399A patent/KR20010042055A/ko not_active Ceased
- 1999-03-16 ES ES99909099T patent/ES2190199T3/es not_active Expired - Lifetime
- 1999-03-16 AT AT99909099T patent/ATE231835T1/de not_active IP Right Cessation
- 1999-03-16 DE DE69905142T patent/DE69905142T2/de not_active Expired - Fee Related
- 1999-03-16 JP JP2000537842A patent/JP2002507590A/ja active Pending
- 1999-03-16 CA CA002324361A patent/CA2324361A1/en not_active Abandoned
- 1999-03-16 IL IL13858999A patent/IL138589A/en not_active IP Right Cessation
2000
- 2000-08-24 ZA ZA200004387A patent/ZA200004387B/xx unknown
- 2000-09-19 NO NO20004662A patent/NO20004662L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
US6346633B1 (en)	2002-02-12
CA2324361A1 (en)	1999-09-30
EP1064253A1 (de)	2001-01-03
JP2002507590A (ja)	2002-03-12
AU756651B2 (en)	2003-01-16
NZ505856A (en)	2002-09-27
IL138589A0 (en)	2001-10-31
ZA200004387B (en)	2001-10-31
BR9908932A (pt)	2005-10-25
IL138589A (en)	2004-08-31
DE69905142T2 (de)	2003-10-16
EP1064253B1 (de)	2003-01-29
NO20004662L (no)	2000-11-17
GB9805866D0 (en)	1998-05-13
AU2846899A (en)	1999-10-18
KR20010042055A (ko)	2001-05-25
ES2190199T3 (es)	2003-07-16
DK1064253T3 (da)	2003-06-23
DE69905142D1 (de)	2003-03-06
CN1293654A (zh)	2001-05-02
NO20004662D0 (no)	2000-09-19
WO1999048857A1 (en)	1999-09-30

Legal Events

Date

Code

Title

Description

2003-09-15

UEP

Publication of translation of european patent specification

Ref document number: 1064253

Country of ref document: EP

2006-12-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE304019T1 (de)	2005-09-15	Inhibitoren des nukleosid-metabolismus
GEP20084488B (en)	2008-09-25	Use of therapeutic agents for treating pain
BG103264A (en)	2000-01-31	Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides
HUP0300195A2 (hu)	2003-07-28	Heterociklusos nátrium/proton-csere inhibitorok és ezeket tartalmazó gyógyszerkészítmények
SE0202133D0 (sv)	2002-07-08	Novel compounds
TR200100075T2 (tr)	2001-08-21	2-Kuinolon ihtiva eden farmasötik bileşimler
DE60112330D1 (en)	2005-09-01	Pyrazolopyridinderivate
IL138590A0 (en)	2001-10-31	Anti-tumour agents
MY106065A (en)	1995-03-31	Antipicornaviral pyridazinamines.
MY139612A (en)	2009-10-30	Benzoxazine derivatives as 5-th6 modulators and uses thereof
HUP9801880A2 (hu)	1998-11-30	Új kriptoficinek, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények
AU1367497A (en)	1997-08-01	Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of prostatic carcinoma
IL140070A0 (en)	2002-02-10	Benzamide derivatives and pharmaceutical compositions containing the same
DE69905142D1 (de)	2003-03-06	Anti-tumor-mittel
MXPA05010651A (es)	2005-12-12	Compuestos de pirazol.
PL357082A1 (en)	2004-07-12	Novel tetrahydropyridines, preparation method and pharmaceutical compositions containing same
DE60201074D1 (en)	2004-09-30	Pyrazolopyridinderivate
BG105539A (bg)	2001-12-29	Елетриптан хидробромид монохидрат
PL335012A1 (en)	2000-02-28	Novel derivatives of indan-1-ole, method of obtaining and composition containing them
BR9604907B1 (pt)	2011-10-18	derivados de nucleosidios homocarbociclico de pirimidinodiona substituìda antiviral e composição contendo derivados de nucleosidios homocarbociclico de pirimidinodiona substituìda antiviral com princìpios ativos.
MY159418A (en)	2017-01-13	New derivatives of flavones, their preparation process, their use as medicaments, pharmaceutical compositions and new use
MXPA04005151A (es)	2004-08-11	Compuestos terapeuticos.
NZ310385A (en)	2000-01-28	Novel derivatives of swainsonine, processes for their preparation and their use as therapeutic agents
TR199801175A1 (xx)	1999-01-18	Tetrahidroimidazo(2,1-a)izokuinolin t�revleri.
MX9801130A (es)	1998-11-29	Tiamacrolidos.