ATE233319T1 - Transfektierte zelllinie, exprimierend dns die für die nmda-r2a rezeptor untereinheit und für isoformen der nmda-r1 untereinheit des menschlichen nmda-rezeptors kodieren - Google Patents
Transfektierte zelllinie, exprimierend dns die für die nmda-r2a rezeptor untereinheit und für isoformen der nmda-r1 untereinheit des menschlichen nmda-rezeptors kodierenInfo
- Publication number
- ATE233319T1 ATE233319T1 AT93924747T AT93924747T ATE233319T1 AT E233319 T1 ATE233319 T1 AT E233319T1 AT 93924747 T AT93924747 T AT 93924747T AT 93924747 T AT93924747 T AT 93924747T AT E233319 T1 ATE233319 T1 AT E233319T1
- Authority
- AT
- Austria
- Prior art keywords
- nmda
- subunit
- receptor
- human
- cell line
- Prior art date
Links
- 102000001708 Protein Isoforms Human genes 0.000 title abstract 4
- 108010029485 Protein Isoforms Proteins 0.000 title abstract 4
- 108090001041 N-Methyl-D-Aspartate Receptors Proteins 0.000 title abstract 3
- 102000004868 N-Methyl-D-Aspartate Receptors Human genes 0.000 title abstract 3
- 108020003175 receptors Proteins 0.000 title abstract 3
- 102000005962 receptors Human genes 0.000 title abstract 3
- HOKKHZGPKSLGJE-GSVOUGTGSA-N N-Methyl-D-aspartic acid Chemical compound CN[C@@H](C(O)=O)CC(O)=O HOKKHZGPKSLGJE-GSVOUGTGSA-N 0.000 abstract 3
- 108010084867 N-methyl D-aspartate receptor subtype 2A Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 239000002299 complementary DNA Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 210000003527 eukaryotic cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929223769A GB9223769D0 (en) | 1992-11-12 | 1992-11-12 | Receptor cloning |
| GB939307026A GB9307026D0 (en) | 1993-04-02 | 1993-04-02 | Receptor cloning |
| PCT/GB1993/002324 WO1994011501A1 (en) | 1992-11-12 | 1993-11-11 | cDNAs ENCODING HUMAN NMDA-22A RECEPTOR SUBUNIT AND ISOFORMS OF THE HUMAN NMDA-R1 RECEPTOR SUBUNIT, TRANSFECTED CELL LINE EXPRESSING THEM |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE233319T1 true ATE233319T1 (de) | 2003-03-15 |
Family
ID=26301962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93924747T ATE233319T1 (de) | 1992-11-12 | 1993-11-11 | Transfektierte zelllinie, exprimierend dns die für die nmda-r2a rezeptor untereinheit und für isoformen der nmda-r1 untereinheit des menschlichen nmda-rezeptors kodieren |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6130058A (de) |
| EP (1) | EP0672140B1 (de) |
| JP (1) | JPH08503362A (de) |
| AT (1) | ATE233319T1 (de) |
| AU (1) | AU5429794A (de) |
| CA (1) | CA2148599C (de) |
| DE (1) | DE69332715T2 (de) |
| DK (1) | DK0672140T3 (de) |
| WO (1) | WO1994011501A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2110934A1 (en) | 1992-12-11 | 1994-06-12 | Robert L. Foldes | Human cns receptors of the nmda-r1 family |
| JPH08509607A (ja) | 1993-04-20 | 1996-10-15 | ザ ソールク インスチチュート バイオテクノロジー／インダストリアル アソシエイツ，インコーポレイテッド | ヒトｎ−メチル−ｄ−アスパラギン酸受容体サブユニット、これをコードする核酸およびその用途 |
| EP0674003A3 (de) * | 1994-03-25 | 1997-09-10 | Allelix Biopharma | Proteine die menschliche CNS Rezeptoren modulieren. |
| GB9414997D0 (en) * | 1994-07-26 | 1994-09-14 | Merck Sharp & Dohme | Receptor cloning |
| US20050037969A1 (en) * | 1999-05-14 | 2005-02-17 | Arbor Vita Corporation | Molecular interactions in hematopoietic cells |
| JP4114029B2 (ja) * | 1999-07-16 | 2008-07-09 | 株式会社セガ | 画像処理装置、画像処理方法及び記録媒体 |
| CA2505786C (en) * | 2002-11-25 | 2011-06-21 | Sequenom, Inc. | Methods for identifying risk of breast cancer and treatments thereof |
| WO2004048546A2 (en) * | 2002-11-25 | 2004-06-10 | Sequenom, Inc. | Methods for identifying risk of breast cancer and treatments thereof |
| WO2005014846A2 (en) * | 2003-07-24 | 2005-02-17 | Sequenom, Inc. | Methods for identifying risk of breast cancer and treatments thereof |
| CA2567973A1 (en) * | 2004-05-27 | 2005-12-15 | Sequenom, Inc. | Methods for identifying risk of breast cancer and treatments thereof |
| WO2017109709A2 (en) | 2015-12-22 | 2017-06-29 | Novartis Ag | A high-throughput assay method for identifying allosteric nmda receptor modulators |
| CN122150571A (zh) * | 2019-09-13 | 2026-06-05 | 欧蒙医学实验诊断股份公司 | 改进的nmda受体自身抗体检测 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4216321A1 (de) * | 1992-05-16 | 1993-11-18 | Basf Ag | Untereinheiten von NMDA-Rezeptoren, Verfahren zu ihrer Herstellung und ihre Verwendung |
-
1993
- 1993-11-11 WO PCT/GB1993/002324 patent/WO1994011501A1/en not_active Ceased
- 1993-11-11 US US08/436,332 patent/US6130058A/en not_active Expired - Fee Related
- 1993-11-11 CA CA002148599A patent/CA2148599C/en not_active Expired - Fee Related
- 1993-11-11 DE DE69332715T patent/DE69332715T2/de not_active Expired - Fee Related
- 1993-11-11 JP JP6511856A patent/JPH08503362A/ja active Pending
- 1993-11-11 AT AT93924747T patent/ATE233319T1/de not_active IP Right Cessation
- 1993-11-11 AU AU54297/94A patent/AU5429794A/en not_active Abandoned
- 1993-11-11 EP EP93924747A patent/EP0672140B1/de not_active Expired - Lifetime
- 1993-11-11 DK DK93924747T patent/DK0672140T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| WO1994011501A1 (en) | 1994-05-26 |
| EP0672140A1 (de) | 1995-09-20 |
| AU5429794A (en) | 1994-06-08 |
| DE69332715D1 (de) | 2003-04-03 |
| CA2148599C (en) | 2004-01-20 |
| US6130058A (en) | 2000-10-10 |
| DK0672140T3 (da) | 2003-03-31 |
| EP0672140B1 (de) | 2003-02-26 |
| CA2148599A1 (en) | 1994-05-26 |
| JPH08503362A (ja) | 1996-04-16 |
| DE69332715T2 (de) | 2003-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |