ATE233319T1 - Transfektierte zelllinie, exprimierend dns die für die nmda-r2a rezeptor untereinheit und für isoformen der nmda-r1 untereinheit des menschlichen nmda-rezeptors kodieren - Google Patents

Transfektierte zelllinie, exprimierend dns die für die nmda-r2a rezeptor untereinheit und für isoformen der nmda-r1 untereinheit des menschlichen nmda-rezeptors kodieren

Info

Publication number: ATE233319T1
Authority: AT; Austria
Prior art keywords: nmda; subunit; receptor; human; cell line
Prior art date: 1992-11-12

Application number

AT93924747T

Other languages

English (en)

Inventor

Bourdelles Beatrice Le

Janice Ann Myers

Paul John Whiting

Original Assignee

Merck Sharp & Dohme

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-11-12

Filing date

1993-11-11

Publication date

2003-03-15

1992-11-12 Priority claimed from GB929223769A external-priority patent/GB9223769D0/en

1993-04-02 Priority claimed from GB939307026A external-priority patent/GB9307026D0/en

1993-11-11 Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme

2003-03-15 Application granted granted Critical

2003-03-15 Publication of ATE233319T1 publication Critical patent/ATE233319T1/de

Links

102000001708 Protein Isoforms Human genes 0.000 title abstract 4
108010029485 Protein Isoforms Proteins 0.000 title abstract 4
108090001041 N-Methyl-D-Aspartate Receptors Proteins 0.000 title abstract 3
102000004868 N-Methyl-D-Aspartate Receptors Human genes 0.000 title abstract 3
108020003175 receptors Proteins 0.000 title abstract 3
102000005962 receptors Human genes 0.000 title abstract 3
HOKKHZGPKSLGJE-GSVOUGTGSA-N N-Methyl-D-aspartic acid Chemical compound CN[C@@H](C(O)=O)CC(O)=O HOKKHZGPKSLGJE-GSVOUGTGSA-N 0.000 abstract 3
108010084867 N-methyl D-aspartate receptor subtype 2A Proteins 0.000 abstract 1
210000004027 cell Anatomy 0.000 abstract 1
238000010367 cloning Methods 0.000 abstract 1
239000002299 complementary DNA Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
210000003527 eukaryotic cell Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Neurosurgery (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Zoology (AREA)
Toxicology (AREA)
Cell Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyrrole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT93924747T 1992-11-12 1993-11-11 Transfektierte zelllinie, exprimierend dns die für die nmda-r2a rezeptor untereinheit und für isoformen der nmda-r1 untereinheit des menschlichen nmda-rezeptors kodieren ATE233319T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB929223769A GB9223769D0 (en)	1992-11-12	1992-11-12	Receptor cloning
GB939307026A GB9307026D0 (en)	1993-04-02	1993-04-02	Receptor cloning
PCT/GB1993/002324 WO1994011501A1 (en)	1992-11-12	1993-11-11	cDNAs ENCODING HUMAN NMDA-22A RECEPTOR SUBUNIT AND ISOFORMS OF THE HUMAN NMDA-R1 RECEPTOR SUBUNIT, TRANSFECTED CELL LINE EXPRESSING THEM

Publications (1)

Publication Number	Publication Date
ATE233319T1 true ATE233319T1 (de)	2003-03-15

Family

ID=26301962

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93924747T ATE233319T1 (de)	1992-11-12	1993-11-11	Transfektierte zelllinie, exprimierend dns die für die nmda-r2a rezeptor untereinheit und für isoformen der nmda-r1 untereinheit des menschlichen nmda-rezeptors kodieren

Country Status (9)

Country	Link
US (1)	US6130058A (de)
EP (1)	EP0672140B1 (de)
JP (1)	JPH08503362A (de)
AT (1)	ATE233319T1 (de)
AU (1)	AU5429794A (de)
CA (1)	CA2148599C (de)
DE (1)	DE69332715T2 (de)
DK (1)	DK0672140T3 (de)
WO (1)	WO1994011501A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2110934A1 (en)	1992-12-11	1994-06-12	Robert L. Foldes	Human cns receptors of the nmda-r1 family
US5849895A (en)	1993-04-20	1998-12-15	Sibia Neurosciences, Inc.	Human N-methyl-D-aspartate receptor subunits, nucleic acids encoding same and uses therefor
EP0674003A3 (de) *	1994-03-25	1997-09-10	Allelix Biopharma	Proteine die menschliche CNS Rezeptoren modulieren.
GB9414997D0 (en) *	1994-07-26	1994-09-14	Merck Sharp & Dohme	Receptor cloning
US20050037969A1 (en) *	1999-05-14	2005-02-17	Arbor Vita Corporation	Molecular interactions in hematopoietic cells
JP4114029B2 (ja) *	1999-07-16	2008-07-09	株式会社セガ	画像処理装置、画像処理方法及び記録媒体
AU2003293130A1 (en) *	2002-11-25	2004-06-18	Sequenom, Inc.	Methods for identifying risk of breast cancer and treatments thereof
CA2505784A1 (en) *	2002-11-25	2004-06-10	Sequenom, Inc.	Methods for identifying risk of breast cancer and treatments thereof
WO2005014846A2 (en) *	2003-07-24	2005-02-17	Sequenom, Inc.	Methods for identifying risk of breast cancer and treatments thereof
US20090258344A1 (en) *	2004-05-27	2009-10-15	Sequenom, Inc.	Methods for identifying risk of breast cancer and treatments thereof
WO2017109709A2 (en)	2015-12-22	2017-06-29	Novartis Ag	A high-throughput assay method for identifying allosteric nmda receptor modulators
EP4028769A1 (de) *	2019-09-13	2022-07-20	Euroimmun Medizinische Labordiagnostika AG	Verbesserter nachweis von nmda-rezeptor-autoantikörpern

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4216321A1 (de) *	1992-05-16	1993-11-18	Basf Ag	Untereinheiten von NMDA-Rezeptoren, Verfahren zu ihrer Herstellung und ihre Verwendung

1993
- 1993-11-11 DE DE69332715T patent/DE69332715T2/de not_active Expired - Fee Related
- 1993-11-11 JP JP6511856A patent/JPH08503362A/ja active Pending
- 1993-11-11 CA CA002148599A patent/CA2148599C/en not_active Expired - Fee Related
- 1993-11-11 AT AT93924747T patent/ATE233319T1/de not_active IP Right Cessation
- 1993-11-11 WO PCT/GB1993/002324 patent/WO1994011501A1/en not_active Ceased
- 1993-11-11 AU AU54297/94A patent/AU5429794A/en not_active Abandoned
- 1993-11-11 EP EP93924747A patent/EP0672140B1/de not_active Expired - Lifetime
- 1993-11-11 DK DK93924747T patent/DK0672140T3/da active
- 1993-11-11 US US08/436,332 patent/US6130058A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US6130058A (en)	2000-10-10
AU5429794A (en)	1994-06-08
DE69332715D1 (de)	2003-04-03
DE69332715T2 (de)	2003-10-16
CA2148599C (en)	2004-01-20
DK0672140T3 (da)	2003-03-31
WO1994011501A1 (en)	1994-05-26
EP0672140A1 (de)	1995-09-20
CA2148599A1 (en)	1994-05-26
EP0672140B1 (de)	2003-02-26
JPH08503362A (ja)	1996-04-16

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Legal Events

Date	Code	Title	Description
2003-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties