ATE233557T1 - Verwendung von konjugiertes linolensäure zur steigerung der aktivität von natural killer- lymphozyten - Google Patents
Verwendung von konjugiertes linolensäure zur steigerung der aktivität von natural killer- lymphozytenInfo
- Publication number
- ATE233557T1 ATE233557T1 AT97945605T AT97945605T ATE233557T1 AT E233557 T1 ATE233557 T1 AT E233557T1 AT 97945605 T AT97945605 T AT 97945605T AT 97945605 T AT97945605 T AT 97945605T AT E233557 T1 ATE233557 T1 AT E233557T1
- Authority
- AT
- Austria
- Prior art keywords
- activity
- natural killer
- increase
- killer lymphocytes
- linolenic acid
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 4
- 210000004698 lymphocyte Anatomy 0.000 title abstract 4
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 title 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 title 1
- 229960004488 linolenic acid Drugs 0.000 title 1
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 title 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000031942 natural killer cell mediated cytotoxicity Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3039496P | 1996-11-05 | 1996-11-05 | |
| PCT/US1997/020098 WO1998019675A1 (en) | 1996-11-05 | 1997-11-04 | Use of conjugated linoleic acid to enhance natural killer lymphocyte function |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE233557T1 true ATE233557T1 (de) | 2003-03-15 |
Family
ID=21854010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97945605T ATE233557T1 (de) | 1996-11-05 | 1997-11-04 | Verwendung von konjugiertes linolensäure zur steigerung der aktivität von natural killer- lymphozyten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5914346A (de) |
| EP (1) | EP0941088B1 (de) |
| JP (1) | JP2001503430A (de) |
| AT (1) | ATE233557T1 (de) |
| AU (1) | AU5104198A (de) |
| CA (1) | CA2267109C (de) |
| DE (1) | DE69719539D1 (de) |
| WO (1) | WO1998019675A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7776353B1 (en) * | 1998-03-17 | 2010-08-17 | Aker Biomarine Asa | Conjugated linoleic acid compositions |
| DE19836339B4 (de) | 1998-08-11 | 2011-12-22 | N.V. Nutricia | Kohlenhydratmischung |
| EP1231913A2 (de) * | 1999-07-09 | 2002-08-21 | Pharmacia Corporation | Behandlung von cyclooxygenase-2 bedingten erkrankungen unter verwendung von conjugierten fettsäureverbindungen |
| US6077868A (en) * | 1999-07-20 | 2000-06-20 | Wisconsin Alumni Research Foundation | Selective inhibition of cyclooxygenase-2 |
| CA2404799C (en) * | 2000-04-06 | 2007-08-07 | Conlinco, Inc. | Conjugated linoleic acid compositions |
| JP4786030B2 (ja) * | 2000-12-27 | 2011-10-05 | 森永乳業株式会社 | ナチュラルキラー細胞活性化剤 |
| US6395782B1 (en) | 2001-03-02 | 2002-05-28 | Wisconsin Alumni Research Foundation | Method of increasing longevity and preventing body weight wasting in autoimmune disease by using conjugated linoleic acid |
| US6479683B1 (en) | 2001-03-06 | 2002-11-12 | Ag Processing Inc | Process for conjugating fatty acid esters |
| US7098352B2 (en) * | 2001-11-16 | 2006-08-29 | Virtus Nutrition Llc | Calcium salt saponification of polyunsaturated oils |
| CA2396840A1 (en) * | 2002-08-06 | 2004-02-06 | Juan Miguel Garro Galvez | New conjugated linolenic acids and methods for commercial preparation, purification and uses |
| CA2436650A1 (en) * | 2003-08-06 | 2005-02-06 | Naturia Inc. | Conjugated linolenic acid (clnatm) compositions: synthesis, purification and uses |
| WO2005063230A1 (en) * | 2003-12-30 | 2005-07-14 | Universite Laval | Use of conjugated linolenic acids for reducing body fat mass |
| JP2005194222A (ja) * | 2004-01-06 | 2005-07-21 | Otsuka Pharmaceut Factory Inc | サイトカイン誘発剤 |
| US20050154059A1 (en) * | 2004-01-13 | 2005-07-14 | Cook Mark E. | Method of treating type III hypersensitive reaction-related diseases and conditions by using conjugated linoleic acid |
| EA200602014A1 (ru) * | 2004-04-30 | 2007-08-31 | ВИРТУС НЬЮТРИШН ЭлЭлСи | Синтез солей одновалентных и двухвалентных металлов полиненасыщенных жирных кислот |
| EP1597978A1 (de) | 2004-05-17 | 2005-11-23 | Nutricia N.V. | Synergie von GOS und polyfruktose |
| US8252769B2 (en) | 2004-06-22 | 2012-08-28 | N. V. Nutricia | Intestinal barrier integrity |
| CN101658678A (zh) * | 2004-09-15 | 2010-03-03 | 森永乳业株式会社 | 筛选具有自然杀伤细胞增殖作用的物质和增殖自然杀伤细胞的方法 |
| KR101148901B1 (ko) | 2004-09-29 | 2012-05-29 | 모리나가 뉴교 가부시키가이샤 | 고혈당 개선용 음식품 |
| PT1835021E (pt) * | 2004-12-28 | 2011-04-29 | Meiji Seika Kaisha | Nova estirpe que confere a um hospedeiro propriedades anti-doença e composição de células bacterianas |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4282265A (en) * | 1980-01-14 | 1981-08-04 | Bristol-Myers Company | Fat compositions for infant formulas |
| IE54795B1 (en) * | 1982-04-29 | 1990-02-14 | Efamol Ltd | Pharmaceutical composition |
| US4603142A (en) * | 1984-06-01 | 1986-07-29 | Wisconsin Alumni Research Foundation | Cholesterol lowering method of use |
| JPS61216658A (ja) * | 1985-03-20 | 1986-09-26 | Agency Of Ind Science & Technol | 生理活性物質を含有する卵、肉、および乳 |
| JPS6398355A (ja) * | 1986-10-16 | 1988-04-28 | Kazumitsu Maruta | 動物用飼料 |
| US5017614A (en) * | 1989-02-17 | 1991-05-21 | Wisconsin Alumni Research Foundation | Methods of preventing oxidation, quenching singlet oxygen and inhibiting mold growth and novel compositions therefor |
| US5070104A (en) * | 1989-02-17 | 1991-12-03 | Wisconsin Alumni Research Foundation | Methods of chelating metal and novel compositions therefor |
| US5045338A (en) * | 1989-09-19 | 1991-09-03 | Nabisco Brands, Inc. | Secondary amide esters as low calorie fat mimetics |
| US5068119A (en) * | 1990-09-28 | 1991-11-26 | Nabisco Brands, Inc. | Acid-hydrolyzable ester derivatives as low calorie fat mimetics |
| CA2097800C (en) * | 1990-12-07 | 2003-04-29 | Edward L. Wheeler | Reduced calorie triglyceride mixtures |
| US5430066A (en) * | 1992-04-29 | 1995-07-04 | Wisconsin Alumni Research Foundation | Methods for preventing weight loss, reduction in weight gain, and anorexia due to immune stimulation |
| US5428072A (en) * | 1992-04-29 | 1995-06-27 | Wisconsin Alumni Research Foundation | Method of increasing the efficiency of feed conversion in animals |
| US5554646A (en) * | 1992-04-29 | 1996-09-10 | Wisconsin Alumni Research Foundation | Method for reducing body fat in animals |
| JP3138358B2 (ja) * | 1993-03-31 | 2001-02-26 | 雪印乳業株式会社 | 共役リノール酸の製造方法およびそれを含有させた食品 |
| US5470839A (en) * | 1993-04-22 | 1995-11-28 | Clintec Nutrition Company | Enteral diet and method for providing nutrition to a diabetic |
| US5814663A (en) * | 1994-08-29 | 1998-09-29 | Wisconsin Alumni Research Foundation | Method for maintaining an existing level of body fat |
| US5760082C1 (en) * | 1994-08-29 | 2001-03-06 | Wisconsin Alumni Res Found | Dietetic foods containing conjugated linoleic acids |
| ES2161969T3 (es) * | 1995-11-14 | 2001-12-16 | Unilever Nv | Grasa comestible para untar. |
-
1997
- 1997-11-04 US US08/963,740 patent/US5914346A/en not_active Expired - Lifetime
- 1997-11-04 CA CA002267109A patent/CA2267109C/en not_active Expired - Lifetime
- 1997-11-04 DE DE69719539T patent/DE69719539D1/de not_active Expired - Lifetime
- 1997-11-04 JP JP52171998A patent/JP2001503430A/ja not_active Ceased
- 1997-11-04 AU AU51041/98A patent/AU5104198A/en not_active Abandoned
- 1997-11-04 EP EP97945605A patent/EP0941088B1/de not_active Expired - Lifetime
- 1997-11-04 AT AT97945605T patent/ATE233557T1/de not_active IP Right Cessation
- 1997-11-04 WO PCT/US1997/020098 patent/WO1998019675A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69719539D1 (de) | 2003-04-10 |
| EP0941088A1 (de) | 1999-09-15 |
| CA2267109C (en) | 2006-08-22 |
| WO1998019675A1 (en) | 1998-05-14 |
| AU5104198A (en) | 1998-05-29 |
| US5914346A (en) | 1999-06-22 |
| EP0941088B1 (de) | 2003-03-05 |
| JP2001503430A (ja) | 2001-03-13 |
| CA2267109A1 (en) | 1998-05-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |