ATE233745T1 - Arzneistoffe - Google Patents
ArzneistoffeInfo
- Publication number
- ATE233745T1 ATE233745T1 AT96945283T AT96945283T ATE233745T1 AT E233745 T1 ATE233745 T1 AT E233745T1 AT 96945283 T AT96945283 T AT 96945283T AT 96945283 T AT96945283 T AT 96945283T AT E233745 T1 ATE233745 T1 AT E233745T1
- Authority
- AT
- Austria
- Prior art keywords
- medicinal substances
- cryptophycin compounds
- novel cryptophycin
- disrupting
- administering
- Prior art date
Links
- 239000000126 substance Substances 0.000 title 1
- PSNOPSMXOBPNNV-VVCTWANISA-N cryptophycin 1 Chemical class C1=C(Cl)C(OC)=CC=C1C[C@@H]1C(=O)NC[C@@H](C)C(=O)O[C@@H](CC(C)C)C(=O)O[C@H]([C@H](C)[C@@H]2[C@H](O2)C=2C=CC=CC=2)C/C=C/C(=O)N1 PSNOPSMXOBPNNV-VVCTWANISA-N 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US914595P | 1995-12-22 | 1995-12-22 | |
| US2507996P | 1996-08-30 | 1996-08-30 | |
| PCT/US1996/020633 WO1997023211A1 (en) | 1995-12-22 | 1996-12-20 | Pharmaceutical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE233745T1 true ATE233745T1 (de) | 2003-03-15 |
Family
ID=26679113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96945283T ATE233745T1 (de) | 1995-12-22 | 1996-12-20 | Arzneistoffe |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0869786B1 (de) |
| JP (1) | JP2000502351A (de) |
| AT (1) | ATE233745T1 (de) |
| AU (1) | AU1469097A (de) |
| CA (1) | CA2241086A1 (de) |
| DE (1) | DE69626544T2 (de) |
| ES (1) | ES2194129T3 (de) |
| WO (1) | WO1997023211A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6680311B1 (en) | 1996-08-30 | 2004-01-20 | Eli Lilly And Company | Cryptophycin compounds |
| CZ64599A3 (cs) * | 1996-08-30 | 1999-10-13 | Eli Lilly And Company | Farmaceutické sloučeniny |
| JP2001513775A (ja) * | 1997-02-26 | 2001-09-04 | イーライ・リリー・アンド・カンパニー | トリペプチドおよびテトラペプチド医薬化合物 |
| IL131162A0 (en) * | 1997-02-26 | 2001-01-28 | Lilly Co Eli | Selective epoxidation process for preparing pharmaceutical compounds |
| EP0870506A1 (de) * | 1997-04-11 | 1998-10-14 | Eli Lilly And Company | Zusammentsetzungen enthaltend ein Cryptophycin Derivat in Kombination mit einem synchronisierten Wirkstoff oder Aktivierungsmittel zur Behandlung von Krebs |
| US6103913A (en) * | 1998-10-16 | 2000-08-15 | Eli Lilly And Company | Process for preparing enollactone derivatives |
| US6376230B1 (en) | 1998-10-16 | 2002-04-23 | Eli Lilly And Company | Stereoselective process for producing intermediates of cryptophycins |
| HK1049787B (en) | 1999-10-01 | 2014-07-25 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5116954A (en) * | 1988-04-06 | 1992-05-26 | Lipha, Lyonnaise Industrielle Pharmaceutique | Pharmaceutically useful flavonoic compounds containing at least one substituent on the benzopyranone ring moiety |
| GB8814813D0 (en) * | 1988-06-22 | 1988-07-27 | Beecham Group Plc | Novel compounds |
| US4845085A (en) * | 1988-08-09 | 1989-07-04 | Merck & Co., Inc. | Antifungal agent |
| US4845086A (en) * | 1988-08-09 | 1989-07-04 | Merck & Co., Inc. | Antifungal agent |
| CA2179490A1 (en) * | 1993-12-21 | 1995-06-29 | Trimurtulu Golakoti | New cryptophycins |
| WO1997008334A1 (en) * | 1995-08-30 | 1997-03-06 | University Of Hawaii | Cryptophycins from aberrant biosynthesis |
| WO1998008829A1 (en) * | 1996-08-30 | 1998-03-05 | Eli Lilly And Company | Pharmaceutical compounds |
| AU4330097A (en) * | 1996-08-30 | 1998-03-19 | Eli Lilly And Company | Pharmaceutical compounds |
-
1996
- 1996-12-20 EP EP96945283A patent/EP0869786B1/de not_active Expired - Lifetime
- 1996-12-20 AU AU14690/97A patent/AU1469097A/en not_active Abandoned
- 1996-12-20 ES ES96945283T patent/ES2194129T3/es not_active Expired - Lifetime
- 1996-12-20 CA CA002241086A patent/CA2241086A1/en not_active Abandoned
- 1996-12-20 AT AT96945283T patent/ATE233745T1/de not_active IP Right Cessation
- 1996-12-20 WO PCT/US1996/020633 patent/WO1997023211A1/en not_active Ceased
- 1996-12-20 DE DE69626544T patent/DE69626544T2/de not_active Expired - Fee Related
- 1996-12-20 JP JP09523866A patent/JP2000502351A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0869786B1 (de) | 2003-03-05 |
| DE69626544D1 (de) | 2003-04-10 |
| ES2194129T3 (es) | 2003-11-16 |
| CA2241086A1 (en) | 1997-07-03 |
| JP2000502351A (ja) | 2000-02-29 |
| EP0869786A4 (de) | 1999-04-14 |
| AU1469097A (en) | 1997-07-17 |
| EP0869786A1 (de) | 1998-10-14 |
| WO1997023211A1 (en) | 1997-07-03 |
| DE69626544T2 (de) | 2004-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |