ATE235504T1 - Verfahren zur kontrollierten synthese von beliebigen peptidmischungen kodierende polynukleotidmischungen - Google Patents

Verfahren zur kontrollierten synthese von beliebigen peptidmischungen kodierende polynukleotidmischungen

Info

Publication number
ATE235504T1
ATE235504T1 AT95943853T AT95943853T ATE235504T1 AT E235504 T1 ATE235504 T1 AT E235504T1 AT 95943853 T AT95943853 T AT 95943853T AT 95943853 T AT95943853 T AT 95943853T AT E235504 T1 ATE235504 T1 AT E235504T1
Authority
AT
Austria
Prior art keywords
peptide
mixtures
polynucleotides
mixture
proportions
Prior art date
Application number
AT95943853T
Other languages
English (en)
Inventor
H Mario Geysen
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Application granted granted Critical
Publication of ATE235504T1 publication Critical patent/ATE235504T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
AT95943853T 1994-12-30 1995-12-15 Verfahren zur kontrollierten synthese von beliebigen peptidmischungen kodierende polynukleotidmischungen ATE235504T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36666294A 1994-12-30 1994-12-30
PCT/US1995/016443 WO1996020947A1 (en) 1994-12-30 1995-12-15 Method for the controlled synthesis of polynucleotide mixtures which encode desired mixtures of peptides

Publications (1)

Publication Number Publication Date
ATE235504T1 true ATE235504T1 (de) 2003-04-15

Family

ID=23443980

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95943853T ATE235504T1 (de) 1994-12-30 1995-12-15 Verfahren zur kontrollierten synthese von beliebigen peptidmischungen kodierende polynukleotidmischungen

Country Status (8)

Country Link
US (1) US5789577A (de)
EP (1) EP0800526B1 (de)
JP (1) JPH10511554A (de)
AT (1) ATE235504T1 (de)
AU (1) AU4522196A (de)
CA (1) CA2208693A1 (de)
DE (1) DE69530119T2 (de)
WO (1) WO1996020947A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6438561B1 (en) * 1998-11-19 2002-08-20 Navigation Technologies Corp. Method and system for using real-time traffic broadcasts with navigation systems
US6917882B2 (en) * 1999-01-19 2005-07-12 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US20030054390A1 (en) * 1999-01-19 2003-03-20 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6376246B1 (en) 1999-02-05 2002-04-23 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6368861B1 (en) 1999-01-19 2002-04-09 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6436675B1 (en) 1999-09-28 2002-08-20 Maxygen, Inc. Use of codon-varied oligonucleotide synthesis for synthetic shuffling
US6961664B2 (en) 1999-01-19 2005-11-01 Maxygen Methods of populating data structures for use in evolutionary simulations
JP2002534965A (ja) 1999-01-19 2002-10-22 マキシジェン， インコーポレイテッド 所望の特徴を有する文字ストリング、ポリヌクレオチドおよびポリペプチドを作製するための方法
US20070065838A1 (en) * 1999-01-19 2007-03-22 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US7024312B1 (en) 1999-01-19 2006-04-04 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US8457903B1 (en) 1999-01-19 2013-06-04 Codexis Mayflower Holdings, Llc Method and/or apparatus for determining codons
US7873477B1 (en) 2001-08-21 2011-01-18 Codexis Mayflower Holdings, Llc Method and system using systematically varied data libraries
US7702464B1 (en) 2001-08-21 2010-04-20 Maxygen, Inc. Method and apparatus for codon determining
ATE542916T1 (de) * 1999-08-18 2012-02-15 Illumina Inc Methoden zur erzeugung von oligonukleotidlösungen
US7430477B2 (en) 1999-10-12 2008-09-30 Maxygen, Inc. Methods of populating data structures for use in evolutionary simulations
US20050095648A1 (en) * 2003-10-30 2005-05-05 Mario Geysen Method for designing linear epitopes and algorithm therefor and polypeptide epitopes
US20100113287A1 (en) * 2004-09-10 2010-05-06 Rosetta Inpharmatics Llc Methods for assessing the representation of nucleic acid molecules in a nucleic acid library
US7642539B2 (en) * 2005-12-13 2010-01-05 Macronix International Co., Ltd. Thin film fuse phase change cell with thermal isolation pad and manufacturing method
US20210147830A1 (en) 2018-06-29 2021-05-20 Thermo Fisher Scientific Geneart Gmbh High throughput assembly of nucleic acid molecules

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5010175A (en) * 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
US5223409A (en) * 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
DE69020143T2 (de) * 1989-02-17 1996-01-25 Chiron Mimotopes Pty Ltd Verfahren zur verwendung und herstellung von peptiden.
ES2118066T3 (es) * 1989-10-05 1998-09-16 Optein Inc Sintesis y aislamiento, exentos de celulas, de nuevos genes y polipeptidos.
US5723286A (en) * 1990-06-20 1998-03-03 Affymax Technologies N.V. Peptide library and screening systems
WO1992002536A1 (en) * 1990-08-02 1992-02-20 The Regents Of The University Of Colorado Systematic polypeptide evolution by reverse translation
US5264563A (en) * 1990-08-24 1993-11-23 Ixsys Inc. Process for synthesizing oligonucleotides with random codons
IL99553A0 (en) * 1990-09-28 1992-08-18 Ixsys Inc Compositions containing oligonucleotides linked to expression elements,a kit for the preparation of vectors useful for the expression of a diverse population of random peptides and methods utilizing the same
ATE199726T1 (de) * 1992-04-15 2001-03-15 Univ Johns Hopkins Synthese von verschiedenen und nützlichen oligonukleotidsammlungen
PL308204A1 (en) * 1992-09-24 1995-07-24 Chiron Corp Synthesis of n-substituted oligomers

Also Published As

Publication number Publication date
DE69530119T2 (de) 2003-09-25
EP0800526B1 (de) 2003-03-26
AU4522196A (en) 1996-07-24
EP0800526A1 (de) 1997-10-15
US5789577A (en) 1998-08-04
CA2208693A1 (en) 1996-07-11
WO1996020947A1 (en) 1996-07-11
JPH10511554A (ja) 1998-11-10
DE69530119D1 (de) 2003-05-08

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