ATE236399T1 - Vorrichtung zum züchten von organischen zellen und erforschung ihrer elektrophysiologischen aktivität und dabei verwendete membran - Google Patents

Vorrichtung zum züchten von organischen zellen und erforschung ihrer elektrophysiologischen aktivität und dabei verwendete membran

Info

Publication number
ATE236399T1
ATE236399T1 AT99923354T AT99923354T ATE236399T1 AT E236399 T1 ATE236399 T1 AT E236399T1 AT 99923354 T AT99923354 T AT 99923354T AT 99923354 T AT99923354 T AT 99923354T AT E236399 T1 ATE236399 T1 AT E236399T1
Authority
AT
Austria
Prior art keywords
cells
support
electrophysiological activity
studying
membrane used
Prior art date
Application number
AT99923354T
Other languages
English (en)
Inventor
Claude Haenni
Luc Stoppini
Original Assignee
Bio Cell Interface S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Cell Interface S A filed Critical Bio Cell Interface S A
Application granted granted Critical
Publication of ATE236399T1 publication Critical patent/ATE236399T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • G01N33/4836—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures using multielectrode arrays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/04—Flat or tray type, drawers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Clinical Laboratory Science (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99923354T 1998-06-08 1999-06-04 Vorrichtung zum züchten von organischen zellen und erforschung ihrer elektrophysiologischen aktivität und dabei verwendete membran ATE236399T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9807596A FR2779443B1 (fr) 1998-06-08 1998-06-08 Dispositif de culture de cellules organiques et d'etude de leur activite electrophysiologique et membrane utilisee dans un tel dispositif
PCT/CH1999/000243 WO1999064559A2 (fr) 1998-06-08 1999-06-04 Dispositif de culture de cellules organiques et d'etude de leur activite electrophysiologique et membrane utilisee dans un tel dispositif

Publications (1)

Publication Number Publication Date
ATE236399T1 true ATE236399T1 (de) 2003-04-15

Family

ID=9527465

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99923354T ATE236399T1 (de) 1998-06-08 1999-06-04 Vorrichtung zum züchten von organischen zellen und erforschung ihrer elektrophysiologischen aktivität und dabei verwendete membran

Country Status (10)

Country Link
US (1) US6689594B1 (de)
EP (1) EP1133691B1 (de)
JP (1) JP2002517225A (de)
AT (1) ATE236399T1 (de)
AU (1) AU4027999A (de)
DE (1) DE69906574T2 (de)
ES (1) ES2195572T3 (de)
FR (1) FR2779443B1 (de)
IL (1) IL140174A (de)
WO (1) WO1999064559A2 (de)

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US7485454B1 (en) * 2000-03-10 2009-02-03 Bioprocessors Corp. Microreactor
IL136232A0 (en) * 2000-05-18 2001-05-20 Bar Ilan University Res Author Measurements of enzymatic activity in a single, individual cell in population
WO2002099408A1 (fr) * 2001-06-05 2002-12-12 Matsushita Electric Industrial Co., Ltd. Capteur de detection de signaux pourvu de multiples electrodes
EP1438385A1 (de) * 2001-10-25 2004-07-21 Bar-Ilan University Interaktiver transparenter biochip-prozessor für einzeln adressierbare zellen
JP4370082B2 (ja) * 2002-08-26 2009-11-25 独立行政法人科学技術振興機構 神経細胞培養マイクロチャンバー
IL154677A0 (en) * 2003-02-27 2003-09-17 Univ Bar Ilan A method and apparatus for manipulating an individual cell
EP1654347B1 (de) * 2003-06-26 2014-06-04 Seng Enterprises Limited Verbesserte Materialien zur Konstruktion von Zellchips, Zellchip-Abdeckungen, Zellchip-Hüllen, prozessierte Zellchips und Verwendungen davon
US8597597B2 (en) * 2003-06-26 2013-12-03 Seng Enterprises Ltd. Picoliter well holding device and method of making the same
US7888110B2 (en) * 2003-06-26 2011-02-15 Seng Enterprises Ltd. Pico liter well holding device and method of making the same
US9200245B2 (en) 2003-06-26 2015-12-01 Seng Enterprises Ltd. Multiwell plate
WO2005008626A1 (en) * 2003-07-11 2005-01-27 University Of North Carolina At Chapel Hill Methods and systems for controlling a computer using a video image and for combining the video image with a computer desktop
US20050064524A1 (en) * 2003-08-11 2005-03-24 Mordechai Deutsch Population of cells utilizable for substance detection and methods and devices using same
ATE430802T1 (de) 2003-08-21 2009-05-15 Monsanto Technology Llc Fettsäuredesaturasen aus primula
WO2005074893A1 (en) * 2004-02-03 2005-08-18 Chemagis Ltd. Stable amorphous forms of montelukast sodium
US7403647B2 (en) * 2004-09-13 2008-07-22 Seng Enterprises Ltd. Method for identifying an image of a well in an image of a well-bearing component
US20080063251A1 (en) * 2004-07-07 2008-03-13 Mordechai Deutsch Method and Device for Identifying an Image of a Well in an Image of a Well-Bearing
US20080009051A1 (en) * 2004-08-25 2008-01-10 Seng Enterprises Ltd. Method and Device for Isolating Cells
WO2006037527A1 (en) * 2004-09-30 2006-04-13 Pamgene Bv Masked solid porous supports allowing fast and easy reagent exchange to accelerate electrode-based microarrays
DE602005023534D1 (de) 2005-01-25 2010-10-21 Seng Entpr Ltd Mikrofluidische vorrichtung zur untersuchung zellen
GB0512216D0 (en) * 2005-06-15 2005-07-27 Capsant Neurotechnologies Ltd Device
GB0512214D0 (en) 2005-06-15 2005-07-27 Capsant Neurotechnologies Ltd Method
US20070141555A1 (en) * 2005-10-11 2007-06-21 Mordechai Deutsch Current damper for the study of cells
US8288120B2 (en) * 2005-11-03 2012-10-16 Seng Enterprises Ltd. Method for studying floating, living cells
US20060223999A1 (en) * 2006-05-10 2006-10-05 Chemagis Ltd. Process for preparing montelukast and precursors thereof
WO2008011876A2 (de) * 2006-07-24 2008-01-31 Biocer Entwicklungs Gmbh Anordnung für online-messungen an zellen
DE102007016629A1 (de) * 2007-04-05 2008-10-09 Micronas Gmbh Sensor zur Erfassung eines toxischen oder gefährlichen Gasgemisches und Betriebsverfahren
US9145540B1 (en) 2007-11-15 2015-09-29 Seng Enterprises Ltd. Device for the study of living cells
EP2237887A2 (de) 2007-12-26 2010-10-13 Seng Enterprises Ltd. Vorrichtung zur untersuchung von lebenden zellen
JP5200888B2 (ja) * 2008-11-21 2013-06-05 大日本印刷株式会社 パターン細胞培養用器具
WO2012147463A1 (ja) * 2011-04-28 2012-11-01 株式会社日立製作所 細胞培養容器および細胞培養装置
CN102680526B (zh) * 2012-05-16 2014-07-02 清华大学 单细胞阵列微芯片及其制造、电测量和电穿孔方法
CN103630579A (zh) * 2013-02-27 2014-03-12 中国科学院电子学研究所 细胞阻抗分析的芯片及仪器
EP4170014A1 (de) 2021-10-21 2023-04-26 Alpvision SA Mikrofluidisches system zur robusten elektrischen langzeitmessung und/oder stimulation von zellkulturen
WO2024145528A1 (en) * 2022-12-29 2024-07-04 The Board Of Trustees Of The Leland Stanford Junior University Devices, systems and methods for electrophysical recordings of suspension cultures

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1124022A1 (ru) * 1983-04-15 1984-11-15 Специальное конструкторское бюро биологического приборостроения АН СССР Камера дл регистрации электрофизиологических характеристик и фиксации потенциала мембраны биологического объекта
US5563067A (en) * 1994-06-13 1996-10-08 Matsushita Electric Industrial Co., Ltd. Cell potential measurement apparatus having a plurality of microelectrodes
FR2733055B1 (fr) * 1995-04-12 1997-12-19 Chemodyne Sa Nouveau dispositif d'etude de cultures organotypiques et ses applications en electrophysiologie
US6303082B1 (en) * 1999-12-15 2001-10-16 Nanogen, Inc. Permeation layer attachment chemistry and method

Also Published As

Publication number Publication date
EP1133691B1 (de) 2003-04-02
DE69906574T2 (de) 2004-01-29
EP1133691A2 (de) 2001-09-19
FR2779443B1 (fr) 2000-08-04
ES2195572T3 (es) 2003-12-01
FR2779443A1 (fr) 1999-12-10
JP2002517225A (ja) 2002-06-18
WO1999064559A2 (fr) 1999-12-16
DE69906574D1 (de) 2003-05-08
IL140174A0 (en) 2002-02-10
IL140174A (en) 2003-12-10
WO1999064559A3 (fr) 2001-07-12
AU4027999A (en) 1999-12-30
US6689594B1 (en) 2004-02-10

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