ATE236907T1 - Misoprostol, verfahren zur deren herstellung mit verwendung eines organometall-kupferkomplexes - Google Patents

Misoprostol, verfahren zur deren herstellung mit verwendung eines organometall-kupferkomplexes

Info

Publication number: ATE236907T1
Authority: AT; Austria
Prior art keywords: misoprostol; reaction; organometall; production; copper complex
Prior art date: 1996-05-17

Application number

AT97303062T

Other languages

English (en)

Inventor

Yee Fung Lu

Raymond So

Dan To

Casimir Antczak

Original Assignee

Torcan Chemical Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-17

Filing date

1997-05-06

Publication date

2003-04-15

1996-05-17 Priority claimed from CA002176763A external-priority patent/CA2176763C/en

1996-05-17 Priority claimed from US08/649,402 external-priority patent/US5684177A/en

1997-05-06 Application filed by Torcan Chemical Ltd filed Critical Torcan Chemical Ltd

2003-04-15 Application granted granted Critical

2003-04-15 Publication of ATE236907T1 publication Critical patent/ATE236907T1/de

Links

238000000034 method Methods 0.000 title abstract 2
OJLOPKGSLYJEMD-URPKTTJQSA-N methyl 7-[(1r,2r,3r)-3-hydroxy-2-[(1e)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl]heptanoate Chemical compound CCCCC(C)(O)C\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC OJLOPKGSLYJEMD-URPKTTJQSA-N 0.000 title abstract 2
229960005249 misoprostol Drugs 0.000 title abstract 2
-1 alkyl lithium compound Chemical class 0.000 abstract 3
125000002524 organometallic group Chemical group 0.000 abstract 2
BZKFMUIJRXWWQK-UHFFFAOYSA-N Cyclopentenone Chemical class O=C1CCC=C1 BZKFMUIJRXWWQK-UHFFFAOYSA-N 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
229910052744 lithium Inorganic materials 0.000 abstract 1
229910000080 stannane Inorganic materials 0.000 abstract 1
229920002554 vinyl polymer Polymers 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/08—Copper compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT97303062T 1996-05-17 1997-05-06 Misoprostol, verfahren zur deren herstellung mit verwendung eines organometall-kupferkomplexes ATE236907T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CA002176763A CA2176763C (en)	1996-05-17	1996-05-17	Misoprostol
US08/649,402 US5684177A (en)	1996-05-17	1996-05-17	Misoprostol

Publications (1)

Publication Number	Publication Date
ATE236907T1 true ATE236907T1 (de)	2003-04-15

Family

ID=25678471

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97303062T ATE236907T1 (de)	1996-05-17	1997-05-06	Misoprostol, verfahren zur deren herstellung mit verwendung eines organometall-kupferkomplexes

Country Status (3)

Country	Link
EP (1)	EP0807634B1 (de)
AT (1)	ATE236907T1 (de)
DE (1)	DE69720587D1 (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3965143A (en) *	1974-03-26	1976-06-22	G. D. Searle & Co.	16-Oxygenated prostanoic acid derivatives
US4087621A (en) *	1974-03-26	1978-05-02	G. D. Searle & Co.	7-{3-Hydroxy-2β-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-oxocyclopent-1α-yl}hept-5-cis-enoic acids and related compounds
US4904820A (en) *	1987-06-09	1990-02-27	G. D. Searle & Co.	Process for substituting a hydrocarbon group

1997
- 1997-05-06 DE DE69720587T patent/DE69720587D1/de not_active Expired - Lifetime
- 1997-05-06 AT AT97303062T patent/ATE236907T1/de not_active IP Right Cessation
- 1997-05-06 EP EP97303062A patent/EP0807634B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0807634A3 (de)	1998-10-21
DE69720587D1 (de)	2003-05-15
EP0807634A2 (de)	1997-11-19
EP0807634B1 (de)	2003-04-09

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Legal Events

Date	Code	Title	Description
2003-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties