ATE236929T1 - Transformierenden waeckstumsfaktor beta krystalle - Google Patents

Transformierenden waeckstumsfaktor beta krystalle

Info

Publication number: ATE236929T1
Authority: AT; Austria
Prior art keywords: growth factor; transforming growth; tgf; factor beta; beta
Prior art date: 1995-07-25

Application number

AT96927031T

Other languages

English (en)

Inventor

Peer Mittl

Markus Gruetter

Tudor Arvinte

Original Assignee

Novartis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-25

Filing date

1996-07-17

Publication date

2003-04-15

1996-07-17 Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh

2003-04-15 Application granted granted Critical

2003-04-15 Publication of ATE236929T1 publication Critical patent/ATE236929T1/de

Links

102000004887 Transforming Growth Factor beta Human genes 0.000 title abstract 4
108090001012 Transforming Growth Factor beta Proteins 0.000 title abstract 4
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 title abstract 4
238000001179 sorption measurement Methods 0.000 abstract 2
239000003795 chemical substances by application Substances 0.000 abstract 1
239000013078 crystal Substances 0.000 abstract 1
238000009510 drug design Methods 0.000 abstract 1
230000001590 oxidative effect Effects 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Compounds Of Unknown Constitution (AREA)
Crystals, And After-Treatments Of Crystals (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Liquid Crystal Substances (AREA)

AT96927031T 1995-07-25 1996-07-17 Transformierenden waeckstumsfaktor beta krystalle ATE236929T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP95810484		1995-07-25
PCT/EP1996/003140 WO1997005166A1 (en)	1995-07-25	1996-07-17	Transforming growth factor beta crystals

Publications (1)

Publication Number	Publication Date
ATE236929T1 true ATE236929T1 (de)	2003-04-15

Family

ID=8221775

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96927031T ATE236929T1 (de)	1995-07-25	1996-07-17	Transformierenden waeckstumsfaktor beta krystalle

Country Status (12)

Country	Link
US (1)	US6294656B1 (de)
EP (1)	EP0840748B1 (de)
JP (1)	JP4246795B2 (de)
AT (1)	ATE236929T1 (de)
AU (1)	AU6700696A (de)
CA (1)	CA2225963C (de)
DE (1)	DE69627340T2 (de)
DK (1)	DK0840748T3 (de)
ES (1)	ES2196164T3 (de)
PT (1)	PT840748E (de)
WO (1)	WO1997005166A1 (de)
ZA (1)	ZA966274B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6079213A (en) *	1997-12-12	2000-06-27	Magnetic Imaging Technologies Incorporated	Methods of collecting, thawing, and extending the useful life of polarized gases and associated accumulators and heating jackets
US6128918A (en) *	1998-07-30	2000-10-10	Medi-Physics, Inc.	Containers for hyperpolarized gases and associated methods
US7622562B2 (en)	2002-06-26	2009-11-24	Zimmer Orthobiologics, Inc.	Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
KR20050090430A (ko)	2002-12-31	2005-09-13	알투스 파마슈티컬스 인코포레이티드	인간 성장 호르몬 결정 및 이것의 제조 방법
US20050074453A1 (en) *	2003-10-02	2005-04-07	Ferree Bret A.	Methods of preventing adhesions following laminectomies and other surgical procedures
EP2338441B1 (de)	2003-12-11	2013-01-23	Isto Technologies Inc.	Teilchenförmiges Knorpelsystem
EP1916964A4 (de)	2005-08-26	2015-11-04	Zimmer Inc	Implantate und verfahren zur behebung, ersetzung und behandlung von gelenkkrankheiten
GB0604966D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Medicaments and proteins
GB0604964D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Protein folding
GB0604938D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Proteins, nucleic acids and medicaments
US8163549B2 (en)	2006-12-20	2012-04-24	Zimmer Orthobiologics, Inc.	Method of obtaining viable small tissue particles and use for tissue repair
CA2671925A1 (en) *	2006-12-21	2008-07-10	Stryker Corporation	Sustained-release formulations comprising crystals, macromolecular gels, and particulate suspensions of biologic agents
CA2684040C (en)	2007-04-12	2016-12-06	Isto Technologies, Inc.	Method of forming an implant using a mold that mimics the shape of the tissue defect site and implant formed therefrom
GB0724204D0 (en) *	2007-12-12	2008-01-23	Renovo Ltd	Methods for inhibition of scarring
US20140178343A1 (en)	2012-12-21	2014-06-26	Jian Q. Yao	Supports and methods for promoting integration of cartilage tissue explants

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1126561B (de)	1960-07-05	1962-03-29	Hoechst Ag	Verfahren zur Herstellung von mikrokristallinem Insulin
DE2256215C3 (de)	1972-11-16	1981-01-08	Hoechst Ag, 6000 Frankfurt	Insulin-Zubereitung mit einem Gehalt an kristallinem Insulin und amorphem Desphenylalanin8' -insulin
EG12098A (en)	1974-04-13	1980-12-31	Hoechst Ag	New pharmaceutical insulin preparations having antidiabetic activity and process for their manufacture
DE2933946A1 (de)	1979-08-22	1981-03-12	Hoechst Ag, 6000 Frankfurt	Insulinkristallsuspension und verfahren zu ihrer herstellung.
DE3327709A1 (de)	1983-07-29	1985-02-07	Hoechst Ag, 6230 Frankfurt	Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DE3327928A1 (de)	1983-08-03	1985-02-21	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung von insulin-derivaten
DE3606163A1 (de)	1986-02-26	1987-08-27	Hoechst Ag	Vorrichtung zur applikation von arzneimittelsuspensionen
ATE101620T1 (de)	1988-06-23	1994-03-15	Hoechst Ag	Mini-proinsulin, seine herstellung und verwendung.
US5322933A (en) *	1992-05-07	1994-06-21	The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services	Crystal structure of TGF-β-2
JPH08503969A (ja)	1993-09-29	1996-04-30	アルコンラボラトリーズ，インコーポレイテッド	増殖因子と組織形成抑制剤を含有する組成物

1996
- 1996-07-17 AT AT96927031T patent/ATE236929T1/de not_active IP Right Cessation
- 1996-07-17 DE DE69627340T patent/DE69627340T2/de not_active Expired - Lifetime
- 1996-07-17 AU AU67006/96A patent/AU6700696A/en not_active Abandoned
- 1996-07-17 JP JP50718197A patent/JP4246795B2/ja not_active Expired - Fee Related
- 1996-07-17 PT PT96927031T patent/PT840748E/pt unknown
- 1996-07-17 CA CA002225963A patent/CA2225963C/en not_active Expired - Fee Related
- 1996-07-17 EP EP96927031A patent/EP0840748B1/de not_active Expired - Lifetime
- 1996-07-17 WO PCT/EP1996/003140 patent/WO1997005166A1/en not_active Ceased
- 1996-07-17 US US09/000,069 patent/US6294656B1/en not_active Expired - Fee Related
- 1996-07-17 DK DK96927031T patent/DK0840748T3/da active
- 1996-07-17 ES ES96927031T patent/ES2196164T3/es not_active Expired - Lifetime
- 1996-07-24 ZA ZA966274A patent/ZA966274B/xx unknown

Also Published As

Publication number	Publication date
ZA966274B (en)	1997-01-27
JP4246795B2 (ja)	2009-04-02
US6294656B1 (en)	2001-09-25
PT840748E (pt)	2003-08-29
JP2000502243A (ja)	2000-02-29
DE69627340T2 (de)	2004-02-05
DK0840748T3 (da)	2003-07-28
AU6700696A (en)	1997-02-26
EP0840748A1 (de)	1998-05-13
DE69627340D1 (de)	2003-05-15
CA2225963A1 (en)	1997-02-13
ES2196164T3 (es)	2003-12-16
CA2225963C (en)	2008-02-05
EP0840748B1 (de)	2003-04-09
WO1997005166A1 (en)	1997-02-13

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2004-02-15

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