ATE237138T1 - Durch gruppen erweiterte fluorophore polymere, die eine hydrophobe und konformativ eingeschrankte mikroumgebung schaffen - Google Patents

Durch gruppen erweiterte fluorophore polymere, die eine hydrophobe und konformativ eingeschrankte mikroumgebung schaffen

Info

Publication number
ATE237138T1
ATE237138T1 AT97904060T AT97904060T ATE237138T1 AT E237138 T1 ATE237138 T1 AT E237138T1 AT 97904060 T AT97904060 T AT 97904060T AT 97904060 T AT97904060 T AT 97904060T AT E237138 T1 ATE237138 T1 AT E237138T1
Authority
AT
Austria
Prior art keywords
hydrophobic
groups
conformatively
fluorophore
create
Prior art date
Application number
AT97904060T
Other languages
English (en)
Inventor
Christopher Bieniarz
Jeffrey B Huff
Michael J Cornwell
Venkata Seshagiri R Tata
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE237138T1 publication Critical patent/ATE237138T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B69/00Dyes not provided for by a single group of this subclass
    • C09B69/10Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/141111Diverse hetero atoms in same or different rings [e.g., alkaloids, opiates, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/17Nitrogen containing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/18Sulfur containing

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AT97904060T 1996-02-01 1997-01-30 Durch gruppen erweiterte fluorophore polymere, die eine hydrophobe und konformativ eingeschrankte mikroumgebung schaffen ATE237138T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/595,092 US5994143A (en) 1996-02-01 1996-02-01 Polymeric fluorophores enhanced by moieties providing a hydrophobic and conformationally restrictive microenvironment
PCT/US1997/001429 WO1997028447A1 (en) 1996-02-01 1997-01-30 Polymeric fluorophores enhanced by moieties providing a hydrophobic and conformationally restrictive microenvironment

Publications (1)

Publication Number Publication Date
ATE237138T1 true ATE237138T1 (de) 2003-04-15

Family

ID=24381697

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97904060T ATE237138T1 (de) 1996-02-01 1997-01-30 Durch gruppen erweiterte fluorophore polymere, die eine hydrophobe und konformativ eingeschrankte mikroumgebung schaffen

Country Status (7)

Country Link
US (1) US5994143A (de)
EP (1) EP1019722B1 (de)
JP (1) JP4255514B2 (de)
AT (1) ATE237138T1 (de)
DE (1) DE69720809T2 (de)
ES (1) ES2197332T3 (de)
WO (1) WO1997028447A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6437099B1 (en) * 1998-01-07 2002-08-20 Hamamatsu Photonics K.K. Fluorescene—activating antisera and IgG fraction therefrom
JP3437094B2 (ja) * 1998-07-03 2003-08-18 松下電器産業株式会社 多波長蛍光偏光法
US20050069962A1 (en) * 2001-10-12 2005-03-31 Archer Robert M Antibody complexes and methods for immunolabeling
US8323903B2 (en) * 2001-10-12 2012-12-04 Life Technologies Corporation Antibody complexes and methods for immunolabeling
DE10331093A1 (de) * 2003-07-09 2005-02-10 Schering Ag Vorrichtung und Verfahren zur direkten quantitativen in vitro-Bestimmung einer in einer Probe enthaltenen Substanz
WO2005119223A1 (en) * 2004-04-14 2005-12-15 Bioprocessors Corp. Compositions of matter useful as ph indicators and related methods
DE102004033050A1 (de) * 2004-07-08 2006-01-26 International University Bremen Gmbh Photostabilisierung von Fluoreszenzfarbstoffen
WO2007053594A2 (en) * 2005-10-31 2007-05-10 Clontech Laboratories, Inc. Large dynamic range proteomic analysis methods and compositions for practicing the same
US7781187B2 (en) * 2005-12-30 2010-08-24 Corning Incorporated Fluorescent dyes
GB2437545B (en) * 2006-04-28 2011-07-06 Novexin Ltd Dextrin-containing reagents for detecting and quantifying proteins
JP2013040136A (ja) * 2011-08-17 2013-02-28 Tosoh Corp 4−アルコキシ−2−(4−アミノスチリル)ベンゾチアゾリウム塩、その製造方法およびそれを用いる核酸の検出方法
JP6190534B2 (ja) 2013-08-22 2017-08-30 ソニー株式会社 水溶性蛍光染料又は有色染料及びその使用方法
CN103525117A (zh) * 2013-10-30 2014-01-22 苏州大学 一种半花菁荧光染料、制备方法及应用
CN106459608A (zh) * 2014-08-02 2017-02-22 株式会社Lg化学 染料复合物、光转换膜和包括其的电子装置
KR102676814B1 (ko) 2015-02-26 2024-06-21 소니그룹주식회사 접합 그룹을 포함하는 수용성 형광 또는 착색 염료
CN104788991B (zh) * 2015-03-04 2017-01-25 苏州大学 一种二氯三嗪反应基半花菁荧光活性染料及其制备方法
CN107580618A (zh) 2016-04-01 2018-01-12 索尼公司 超亮二聚或多聚染料
CN109415574B (zh) 2016-04-01 2021-05-28 索尼公司 具有刚性间隔基团的超亮二聚体或聚合物染料
JP7069033B2 (ja) 2016-04-06 2022-05-17 ソニーグループ株式会社 スペーシングリンカー基を有する超明色ダイマーまたはポリマー染料
JP7527537B2 (ja) 2016-05-10 2024-08-05 ソニーグループ株式会社 ペプチド骨格を有する超明色ポリマー染料
WO2017197014A2 (en) * 2016-05-10 2017-11-16 Sony Corporation Compositions comprising a polymeric dye and a cyclodextrin and uses thereof
AU2017264861B2 (en) 2016-05-11 2021-09-23 Sony Group Corporation Ultra bright dimeric or polymeric dyes
WO2017214165A1 (en) 2016-06-06 2017-12-14 Sony Corporation Ionic polymers comprising fluorescent or colored reporter groups
US12018159B2 (en) 2016-07-29 2024-06-25 Sony Group Corporation Ultra bright dimeric or polymeric dyes and methods for preparation of the same
JP7551056B2 (ja) 2017-10-05 2024-09-17 ソニーグループ株式会社 プログラマブルなポリマー薬物
EP3691689A1 (de) 2017-10-05 2020-08-12 Sony Corporation Programmierbare dendritische arzneimittel
JP2021503450A (ja) 2017-11-16 2021-02-12 ソニー株式会社 プログラム可能なポリマー薬
JP7813098B2 (ja) 2018-01-12 2026-02-12 ソニーグループ株式会社 生物学的に活性な化合物を含む剛性間隔基を有するポリマー
JP2021510698A (ja) 2018-01-12 2021-04-30 ソニー株式会社 生物学的に活性な化合物を含むホスホアルキルリボースポリマー
CN111565757A (zh) 2018-01-12 2020-08-21 索尼公司 包含生物活性化合物的磷酸烷基聚合物
KR102742386B1 (ko) 2018-03-19 2024-12-16 소니그룹주식회사 형광 신호 향상을 위한 2가 금속의 사용
WO2019182766A1 (en) 2018-03-21 2019-09-26 Sony Corporation Polymeric tandem dyes with linker groups
KR102854332B1 (ko) 2018-06-27 2025-09-03 소니그룹주식회사 디옥시리보오스를 포함하는 링커 군을 갖는 중합체성 염료
EP3820944A1 (de) 2018-07-13 2021-05-19 Sony Corporation Polymere farbstoffe mit einem gerüst mit organophosphateinheiten
WO2021062176A2 (en) 2019-09-26 2021-04-01 Sony Corporation Polymeric tandem dyes with linker groups
JP7816141B2 (ja) 2019-09-30 2026-02-18 ソニーグループ株式会社 ヌクレオチドプローブ
CN111500110B (zh) * 2020-04-28 2022-09-06 陕西大风印务科技有限公司 烟用包装纸用透明油墨及其涂层、烟用包装纸
EP4256078A1 (de) 2020-12-07 2023-10-11 Sony Group Corporation Abstandslinkergruppendesign zur helligkeitsverstärkung in dimeren oder polymeren farbstoffen

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619990A (en) * 1985-03-11 1986-10-28 Minnesota Mining And Manufacturing Company Polymeric dyes with pendent chromophore groups capable of undergoing thermoplastic deformation
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5002883A (en) * 1987-10-30 1991-03-26 Abbott Laboratories Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents
AU622426B2 (en) * 1987-12-11 1992-04-09 Abbott Laboratories Assay using template-dependent nucleic acid probe reorganization
DE3921498A1 (de) * 1988-09-28 1990-03-29 Bayer Ag Polymer-gebundene-farbstoffe, verfahren zu deren herstellung und verwendung
US5401469A (en) * 1989-04-19 1995-03-28 Ibiden Co., Ltd. Plastic optical biomaterials assay device
DE69118930T2 (de) * 1990-01-26 1997-01-09 Abbott Lab Verbessertes Verfahren zur Amplifikation von Nuklein säurezielsequenz, einsetzbar für die Polymerase und Ligasekettenreaktion
US5401847A (en) * 1990-03-14 1995-03-28 Regents Of The University Of California DNA complexes with dyes designed for energy transfer as fluorescent markers
DE4114482A1 (de) * 1991-05-03 1992-11-05 Bayer Ag Polymere farbstoffe, verfahren zu deren herstellung und deren verwendung
AU1929292A (en) * 1991-05-14 1992-12-30 Hybritech Incorporated Polymeric compositions having bound antibodies
EP0708837B1 (de) * 1993-07-13 2006-03-08 Abbott Laboratories Durch fluoreszierenden polymer markierte konjugate und zwischen produkte

Also Published As

Publication number Publication date
DE69720809D1 (de) 2003-05-15
ES2197332T3 (es) 2004-01-01
EP1019722B1 (de) 2003-04-09
WO1997028447A1 (en) 1997-08-07
DE69720809T2 (de) 2004-04-01
US5994143A (en) 1999-11-30
JP4255514B2 (ja) 2009-04-15
JP2000509412A (ja) 2000-07-25
EP1019722A1 (de) 2000-07-19

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